T. MITCHELL PRUDDEN, M.D.

[Dr. Prudden is Professor of Pathology in the College of Physicians

and Surgeons, New York. He has bestowed especial attention upon

the means of preventing disease: in that important field he has

written three capital manuals, all published by G. P. Putnam's

Sons, New York:--"Story of the Bacteria," "Dust and Its Dangers,"

"Water and Ice Supplies." His other works, intended for the

professional reader, are of the highest authority. The article

here given appeared in _Harper's Magazine_, March, 1894; copyright

by Harper & Brothers, who have granted permission to reprint.

In May, 1902, these pages were revised by Dr. Prudden.]

It is commonly neither wise nor necessary for people not professionally

concerned to think much about disease, or weigh anxiously the chance or

mode of its acquirement. But now and then conditions arise which demand

general attention and instruction regarding certain diseases in order

that a great, threatening calamity may be averted. Such a condition

faces the people in all lands to-day in the appalling prevalence of

tuberculosis. A disease which in mild or severe form affects at least

one-half of the whole human race, and which causes the death of full

one-seventh of all who pass away, killing about one-third of those who

perish between the ages of fifteen and forty-five--a disease which is

most insidious in its onset, and often relentless in its course, and

which may be largely prevented--is one about which we cannot be

indifferent, and should not be longer inactive.

There has long been reason for believing that tuberculosis is a

communicable disease. Its prevalence in certain families and

communities, its frequent occurrence in those who have personally

attended upon its victims, its onset in those who have occupied

apartments vacated by consumptives--such facts observed over and over

again abundantly justify the belief in its communicability. Up to the

commencement of the last decade the cause of the disease was altogether

unknown, and no definite data were at hand which could enable us to fix

upon a feasible plan for limiting its ravages. But in these later years

a great light has been thrown upon this and other kindred diseases.

Most intelligent people are aware that within the past decade a new

field in the domain of life has been revealed and widely explored. It

has been learned that in earth and air and water there exist countless

myriads of living things so minute as to lie far beyond the limits of

the unaided vision, and yet in the aggregate so potent in the

maintenance of the cycle of life upon earth that without their activity

all life would soon cease to be, and the elements which for a short span

fall under the sway of the life forces in all higher animals and plants

would lapse finally and irrevocably into their primal state. These tiny

organisms are called germs, microbes, or micro-organisms. One great and

important group of them belongs among the microscopic plants called

bacteria. These bacteria as a class are important in their economy of

nature, because they live for the most part on dead organic

material--that is, such material as has once formed a portion of some

living thing.

The world's store of available oxygen, hydrogen, carbon and nitrogen,

out of which all living beings are largely formed, is limited, and if

after these have served their temporary uses, as the medium through

which that mysterious potency called life alone can find expression,

they were not speedily released, new generations of living beings could

neither assume nor maintain their place in the great cycle of life. And

so these tiny plants, year in, year out, by day and by night, unseen and

mostly unheeded, are busy always in making possible the return of each

year's visible vegetation and the maintenance of an unbroken succession

of generations in man and beast.

Different groups and races among the bacteria have different

habitations, and vary widely in their special powers. Complex and

powerful as is the aggregate result which they accomplish in the world,

the performances of the individual are comparatively simple. They are

most liberally endowed with the capacity for multiplication, and each

germ acts as a tiny chemical laboratory, taking into itself the organic

matter on which it feeds, and resolving it into new compounds. Some of

the latter are used in building up and maintaining its own body, while

others are given off into the surrounding media.

We are but just beginning to peer at the mysterious processes which go

on under the influence of the bacteria in this underworld of life, and

to realize that all the lore which unwearied toilers in the past have

gathered in their studies of the visible forms of animals and plants,

makes but one of the many chapters in nature's story-book of life.

But this new and stimulating point of view, toward which the studies of

the past decade have led us, does not look so largely into the domain of

the practical that it would greatly attract the majority of business and

pleasure and _ennui_ ridden mankind were it not for one very practical

fact which these recent studies have revealed. This is, that among the

myriads of altogether beneficent bacteria which people the earth, and

air, and water, there are a few forms which have chosen out of all the

world as their most congenial residence the bodies of men. But even this

would be of only passing interest to most people were it not still

further unfortunately true that in the performance of their simple

life-processes these man-loving bacteria, feeding on the tissues of

their host, and setting free certain subtle poisons in his blood, each

after its kind, can induce those disturbances of the body's functions

and those changes in its structure which we call disease.

The diseases caused by the growth of germs in the body are called

infectious. The germs causing some of the infectious diseases are given

off from the bodies of their victims in such form as to be readily

transmitted through the air to others, in whom they may incite similar

disease. Such diseases are spoken of as readily communicable, though it

is not actually the disease itself, but only the germ causing it, which

is transmitted. In other infectious diseases transmission but rarely

occurs. Many infectious diseases are very easily communicated from the

sick to the well under unsanitary and uncleanly conditions, which with

proper care are very little liable to spread.

I need not here put on parade the whole uncanny list of germ diseases,

in which tuberculosis stands foremost, followed by pneumonia,

diphtheria, typhoid fever, scarlatina, cholera, small-pox, and the rest.

Nor need I call to mind the means by which our growing knowledge in this

domain has been day by day laid under tribute for suggestions of hope

and safety for the stricken. It is a record of brilliant conquest in

nature, and already of far-reaching beneficence to man.

But the great fundamental advance which signalizes the past decade is

the lifting of this whole class of fateful germ diseases out of the

region of the intangible and mysterious, and their establishment, on the

basis of positive experimental research, in the domain of the

comprehensible and definite. The things which cause them are no longer

for us mysterious emanations from the sick, or incorporate expressions

of malign forces against which conjurations or prayers could alone

promise protection, but they are particulate beings, never

self-engendered, never evolved in the body, always entering from

without--things which we can see and handle and kill.

Let us now glance at the germ called the tubercle bacillus, the germ

which induces and which alone can induce tuberculosis. It does not exist

and thrive in the body of men or animals in health. Without the entrance

of this particular germ into the human body from without, tuberculosis

cannot develop in it. Without the transmission of this germ in some way

or other in a living condition from the sick to the well, tuberculosis

cannot spread. In the life-story of this tiny germ lie both the potency

for mischief which we deplore and the secret of our release from its

bondage.

The tubercle bacillus is a little colourless, rod-like plant, so small

that even many thousands of them piled together would make a heap far

too small to be visible to the naked eye. It cannot move about, nor can

it grow without moisture, nor at a temperature much above or much below

that of the human body. The material on which it feeds must be very

nicely adapted to its requirements, and it has no lurking and growing

places in nature outside of the bodies of men and a few warm-blooded

animals. It can be cultivated artificially in the laboratory, and we

know more about its life and peculiarities than about almost any other

germ. While it can remain alive in a dried state for many weeks, it is

readily killed by heat, by sunlight, and by many of those chemical

substances which we call disinfectants. It does not flourish equally

well in the bodies of all human beings.

When once it gains lodgment in a body suited to its growth it multiplies

slowly, each germ dividing and subdividing, taking from the tissues

material for its growth, and returning to them certain subtle poisons

which it sets free. The action of the tubercle bacillus is peculiar in

that it stimulates the cells of the body, wherever it may lodge and

grow, to the formation of little masses of new tissue, which we call

tubercles. These tubercles are as a rule short-lived, and, if the

disease progresses, tend to disintegrate. If the tubercles have grown in

such situations as to make this possible, as in the intestinal canal or

the lungs, the disintegrated and broken-down material, often containing

myriads of the living germs, may be cast off from the body. In

tuberculosis of the lungs, or consumption, this waste material is thrown

off with the sputum [spittle]. While almost any part of the body may be

affected, tuberculosis of the lungs is by far the most common form of

the disease.

It follows from what has been said that the only way in which we can

acquire tuberculosis is by getting into our bodies tubercle bacilli from

tuberculous men or animals. The only animals liable to convey the

disease to man are tuberculous cattle, and these through the use of

either meat or milk. The danger from the use of uncooked meat or the

unboiled milk from tuberculous cattle is real and serious, but it will

not be considered here at length, because the great and prevailing

danger of infection comes from another source.

Almost as soon as the significance of the tubercle bacillus was

established, a series of studies was undertaken on the possibility of

the spread of the disease by the breath or exhalations of the persons of

consumptives. These studies at once showed that the tubercle bacillus

cannot be given off into the air of the breath from the moist surfaces

of the mouth and air passages, nor from any material which may come from

them while this material remains moist, nor from healthy unsoiled

surfaces of the body. The establishment of this fact is of far-reaching

consequence, because it shows that neither the person nor the breath of

the consumptive is a direct source of danger, even to the most constant

and intimate attendants.

While the discharges from the bowels in persons suffering from

tuberculosis of the intestinal tract may contain many living bacilli,

the usual mode of disposal of these discharges protects us from any

considerable danger from this source.

It is the sputum after its discharge from the body on which our

attention must be fixed. While the sputum is moist it can, as a rule, do

no harm, unless it should be directly transmitted to those who are well

by violent coughing, sneezing, etc., by the use of uncleansed cooking or

eating utensils, by soiled hands, or by such intimate personal contact

as kissing or fondling. But if in any way the sputum becomes dried, on

floors or walls or bedding, on handkerchiefs or towels, or on the person

of the patient, it may soon become disseminated in the air as dust, and

can thus be breathed into the lungs of exposed persons.

The wide distribution of tubercle bacilli in the air of living-rooms,

and in other dusty places where people go, is due partly to the

frequency of the disease and the large numbers of living bacilli which

are cast off in the sputum (sometimes millions in a day), and partly to

the fact that many of the victims of consumption go about among their

fellows for purposes of business or pleasure for months or years. So

each consumptive, if not intelligently careful, may year after year be

to his fellow-men a source of active and serious and continual

infection.

This, then, the dried, uncared-for sputum of those suffering from

pulmonary tuberculosis, is the great source of danger; this the means so

long concealed by which a large part of the human race prematurely

perishes. Let but this discharged material be rendered harmless or

destroyed before it dries in all cases, and the ravages of this scourge

would largely cease. This is not a theoretic matter only, for again and

again have the living and virulent germs been found clinging to the

walls and furniture and bedding and handkerchiefs of consumptive

persons, and in the dust of the rooms in which they dwell. A malady

whose victims far outnumber those of all other infectious diseases put

together, sparing neither rich nor poor, seizing upon life while it is

as yet only a promise, but most inexorable in the fulness of its

tide--this malady can be largely prevented by the universal and

persistent practice of intelligent cleanliness.

We have learned in the past few years one fact about tuberculosis which

is of incalculable comfort to many, and that is that the disease is not

hereditary. It is very important that we should understand this, because

it seems to contradict a long-prevalent tradition, and a belief still

widely and sorrowfully entertained. Bacteria, and especially most

disease-producing bacteria, are very sensitive in the matter of growth

and reproduction to the conditions under which they are placed, and

especially to the material on which they feed. So that a germ which can

induce serious disease in one species of animal is harmless in the body

of a different though closely allied form. More than this, different

individuals of the same species, or the same individual at different

times, may have the most marked differences in susceptibility in the

presence of disease-producing germs. What this subtle difference is we

do not know. Whether the body at one time affords a congenial soil to

the invading germs and at another does not, whether its marvelous and

complex powers of resisting the virulent tendencies of disease-producing

bacteria at one period or in one individual are more vigorous than in

another, and vary at different times, we do not certainly know. This,

however, we do know, that certain individuals are more likely than

others to yield to the incursions of the tubercle bacillus. This

vulnerability in the presence of invading germs we call susceptibility,

and susceptibility to the action of the tubercle bacillus is hereditary.

It is not the disease, tuberculosis, which comes into the world with

certain individuals or with successive children of the same family, but

the aptitude to contract it should external conditions favour. What

subtle impress on the cells which are to develop into the new individual

renders him more than another an easy prey to the tubercle bacillus

should it later find lodgment in his body we do not know, and we may

not hope soon to be enlightened, since all the intricate mysteries of

heredity seem involved in the problem. But this we do know, that how

ever much the child of tuberculous parents or a member of a tuberculous

family may be predisposed to the disease, he cannot acquire tuberculosis

unless by some mischance the fateful germ enters his body from without.

What has been all through these years regarded as the strongest proof of

the hereditary transmission of tuberculosis--namely, the occurrence of

the disease in several members of the same household--is, in the new

light, simply the result of household infection--the breathing of air

especially liable to contain the noxious germs, or their entrance in

some other way into the bodies of persons especially sensitive to their

presence. I do not mean to imply that under no conditions can the

tubercle bacillus be transmitted from the mother to the child before its

birth. In a few instances this is believed to have happened. But its

occurrence is so extremely infrequent that it may be regarded as

accidental, and of no serious importance from our present point of view.

But it will perhaps be said, "If the tubercle bacilli are so widely

diffused, why do we not all acquire tuberculosis, and why was the world

not long since depopulated?" In order to explain this matter I must ask

the reader to look with me for a moment at some of the body's natural

safeguards against bacterial and other invaders from the air. It has

been found that a person breathing in germ and dust-laden air through

the nose breathes out again air which is both dust and germ free. The

air passages of the nose are tortuous, and lined with a moist membrane,

against which the air impinges in its passage. On these moist surfaces

most of the solid suspended particles, the germs among them, are caught

and held fast, and may be thrown off again by secretion. In breathing

through the mouth this safeguard is not utilized. Again, the upper

passages leading to the lungs are lined with a delicate membrane of

cells, whose free surfaces are thickly beset with tiny hairlike

projections. These projections are constantly moving back and forth with

a quick sweep, in such a way that they carry small particles which may

have escaped the barriers above up into the mouth, from which they may

be readily discharged. In this way much of the evil of breathing dust

and germ-laden air is averted. But in spite of these natural safeguards

a great deal of foreign material does, under the ordinary conditions of

life indoors or in dusty places, find lodgment in the delicate recesses

of the lungs. The body tolerates a good deal of the deleterious

material, but its overtasked toleration fails at last, when serious

disease may ensue.

When ordinary forms of living bacteria get into the tissues of the body,

a very complex cellular mechanism, not fully understood, usually

results in their destruction and ultimate removal. In the presence of

the tubercle bacillus the body cells are often able to build a dense

enclosing wall around the affected region, shutting it off from the rest

of the body. This is one of the modes of natural cure. The body cells

are sometimes able, if sustained by nourishing food and an abundance of

fresh air, to carry on, year after year, a successful struggle with the

invading germs, so that the usefulness and enjoyment of life are but

little interfered with. Finally, a certain proportion of human beings

seem to be endowed at birth with some as yet unknown quality in the

cells or fluids of the body which naturally unfits them for the life

uses of the tubercle bacillus, and so renders the individual for longer

or shorter periods practically immune.

Others, on the contrary, are, as we have seen, from birth unusually

susceptible. This inherited susceptibility to the incursions of the

tubercle bacillus, should this find lodgment in the body from without,

by no means always reveals itself in any apparent lack of vigour or

robustness of the body. Still, any habit or mode of life which

diminishes the bodily vigour, whether in those predisposed to this

malady or in the apparently immune, and gives it a leaning toward

disease, diminishes, as a rule, the chances of a successful contest with

the bacillus. And so it is that in spite of the wide distribution of

these fateful germs in frequented places, and the tendency of certain

vulnerable persons to succumb to their ravages, so many people are not

affected by them, and so many, although not altogether escaping their

malign influence, are yet able to wrest at least a moiety of life from

the hand of the great destroyer.

The degree of success which may attend our crusade against tuberculosis

will largely depend upon the wide diffusion of the knowledge of its

communicability by means of the sputum dried and powdered and floating

in the air as dust, and the intelligent persistence with which the

morbid material may be safely cared for at its sources. The resolute

avoidance by consumptives of the not only filthy but dangerous practice

of spitting upon floors or streets, or anywhere else except into proper

receptacles; the use of receptacles which may be and are frequently and

thoroughly cleansed, and, best of all, of water-proof paper cups, which

with their contents may be burned; or, when circumstances require, the

receiving of the dangerous material on cloths or Japanese paper napkins,

which may be destroyed by fire, and not on more valuable handkerchiefs

on which the sputum is allowed to dry while in use or before

disinfection and washing; scrupulous care by others of the sputum of

those too ill to care for it themselves--these are the comparatively

simple means from which we may most confidently expect relief. The

details of these precautions and their adaptation to the special

circumstances of those suffering from the disease can be most wisely

left to the physician, and though of paramount importance, need not

further engage our attention here.

To the consumptive himself these measures are not without a vital

significance. For his chances of recovery may be in no small degree

diminished if he be more or less constantly liable to a fresh infection

from material which he has once got rid of, and which should have been

destroyed.

The great volumes of fresh, moving air which we encounter out-of-doors

in properly cleansed streets usually so greatly dilutes the dust, of

whatever kind, that little apprehension need be felt from its presence.

When, however, in crowded cities, the streets are, as is nearly always

the case, save for a few favored localities, filthy, and but fitfully

cared for; when choking dust clouds must be encountered by the citizen

during the haphazard and slatternly essays at cleaning made by untrained

and irresponsible sweepers; we cannot ignore a danger from street dust

which may well incite grave apprehension. The citizen can, if he must,

run from the presence of cloud-enwrapped machines furiously whirled

along half-sprinkled pavements; he may avoid a block on which the

hand-sweepers, in the absence or in disregard of rules, ply their

nefarious brooms over unwet surfaces, because too indolent or

indifferent to sprinkle them--these things he can do if he be not

willing or ready to apply the citizen's remedy for municipal misrule.

But it is in rooms either of dwelling or assembling places that the ill

effects of infectious dust are most potent, because the air is here not

so constantly renewed as it is out-of-doors, and is liable to be

breathed over and over again. Dust which gets into houses does not

readily leave them, unless special and intelligent means be directed to

its removal. We do not usually realize that, though the air itself in

inhabited rooms is constantly changing more or less rapidly by

diffusion, by draughts, or by purposed ventilation, fine dust particles

are not removed under the same influences in proportionate degree. They

cling more or less tenaciously to all surfaces on which they have

settled, and especially to fabrics, so that currents of abundant force

and sufficient distribution to change the air may and usually do leave

the lodged dust particles almost entirely undisturbed.

One of the most threatening tendencies of modern times in matters of

health is that of overcrowding in cities, and the great element of

danger from this overcrowding is not only and not chiefly the

insufficiency of air in living-rooms and the lack of ready means for its

renewal, but the accumulation in this air of infectious germs floating

with the dust. Abundant water supply and good sewerage have rendered

possible and measurably safe, so far as the ordinary waste of life is

concerned, the building of vast tenements which swarm with people. But

the means of getting pure air, and especially of disposing of infectious

material often floating in it when it is confined, have not at all kept

pace with the demands of health and cleanliness.

But when we return to larger and more liberally furnished dwellings of

the well-to-do classes, we are not reassured, for in some respects the

rich are sadly handicapped by the "tyranny of things." Of course, long

and thick piled carpets afford persistent lurking-places for infectious

as well as other dust. Certainly heavy hangings in a measure hinder the

detergent action of the sunlight, shut the used air in and the fresh air

out, and shelter floating matter which might otherwise escape. Without

doubt, complex upholstery with roughened fabrics increases the

difficulties in the maintenance of cleanliness. But the usage of the

householder in these matters will, after all, depend upon whether his

practical devotion be most at Fashion's or Hygeia's shrine. We may hope

for the coming of a time when clean, clear, airy, simply furnished

living-rooms shall replace the stuffy, fabric strewn apartments in which

the fashionable citizen so much delights to-day.

In one particular, however, the devotion to cleanliness may be

unreservedly insistent, and that is that in the cleaning of

living-rooms, whether occupied by the sick or the well, the distinct and

recognized purpose of the operation shall be to remove, and not simply

to stir up, the ever-gathering dust. The past few years, so beneficently

signalized by the exploitation of the new germ lore, have seen marked

departures from the traditional sweepings and dustings of a past era;

and the emancipation of the housekeeper, and incidentally of the

household, from the thrall of the pestiferous feather duster seems

fairly under way. Still, some of the old barbarous travesties upon

cleaning widely persist. The dry broom still seeks out in the deep

recesses of the carpets not the coarser particles of dirt alone, but the

hordes of living germs which were for the time safely ensconced, and

among these such malignant forms as the chances of the day have

gathered. These all are set awhirl in the air; some collect upon salient

points of the fittings and furnishings; many stay with the operator, to

vex for hours the delicate breathing passages or the deeper recesses of

the lungs. Then in the lull which follows, gravity reasserts its sway,

and the myriad particles, both the living and the dead, slowly settle to

the horizontal surfaces, especially to the carpets. Then the feather

duster comes upon the scene, and another cyclone befalls. The result of

it all is that the dust has finally been forced to more or less

completely abandon the smooth and shining surfaces where it would be

visible, and is largely caught in the surface roughness of the carpets

or upholstery or hangings, ready at the lightest footfall or the

chariest touch to dance into the air again, and be taken into the lungs

of the victims of the prevailing delusion--the delusion that the way to

care for always obnoxious and offensive and often dangerous dust is not

to get it out of the house, but to keep it stirring in the air until at

last it has settled where it does not vex the eye.

By the use of moist tea leaves in the sweeping of carpets, by the use of

soft-textured fabrics, frequently shaken out-of-doors, or by moist

cloths or chamois in dusting, much useless dust-scattering may be

avoided. But no matter what the means employed, the final purpose of

every household cleaning should be to get the dust, not afloat, but

away.

Probably the most serious source of infection which one is liable to

encounter in the usual ways of life is the occupancy at hotels of

bed-rooms vacated by consumptives without subsequent efficient

cleansing, and travel in sleeping cars. I need not enter here into the

harrowing details of desperate uncleanness which the ordinary railway

travel brings to light. It is to be hoped that popular demand for reform

in the routine of hotel-keepers and railroad managers in the matter of

ordinary sweeping and dusting, and in the precautions against the spread

of tuberculosis, may soon usher in among them a day of reasonable

sanitary intelligence.

A belief in the communicability of tuberculosis is becoming widely

diffused, and it would seem to be desirable, on the ground of policy

alone, for the managers of summer, and especially of winter resorts

frequented by consumptives, to let it be known in no uncertain way that

their precautions against the spread of infectious diseases are

effectually in line with the demands of modern sanitary science.

The members of families bearing a hereditary susceptibility to the

acquirement of this disease should strive to foster those conditions

which favour a healthy, vigorous life in occupation, food, exercise and

amusement and remember that for them more than for others it is

important to avoid such occupations and places as favour the

distribution, in the air or otherwise, of the tubercle bacillus.

But when the individual has done what he can in making his surroundings

clean, and in thus limiting the spread of the tubercle bacillus, there

still remains work for municipal and State and national authorities in

diffusing the necessary knowledge of the disease and its modes of

prevention; in directly caring for those unable to care for themselves;

in securing for all such freedom from contact with sources of the

disease as the dictates of science and humanity may require.

To health boards, either national or local, must be largely entrusted

the primary protection of the people against the danger from tuberculous

cattle.

A national bureau of health might be of incalculable service in

stimulating and harmonizing measures for the suppression of tuberculosis

in various parts of the land, and in fostering research in lines which

promise large practical return in the saving of life.

Tuberculosis has in this country been officially almost entirely ignored

in those practical measures which health boards universally recognize as

efficient in the suppression of this class of maladies. Physicians are

not now generally required to report it to the local health boards.

Systematic official measures of disinfection are not widely practised.

But such official measures have been found extremely useful in the

limitation of other communicable diseases. While consumption must

logically be classed with diphtheria and scarlatina and small-pox as a

communicable germ disease, it is, in fact, in the light of our present

knowledge, when intelligently cared for, so little liable to spread that

it is properly exempt from some of those summary measures which health

authorities are justified in adopting with the more readily and less

avoidably communicable maladies. Moreover, consumption is apt to involve

such prolonged illness, and so often permits affected persons for months

and years to go about their usual avocations, that general isolation

would be both impracticable and inhumane. Moreover, for reasons which

it is hoped are evident to the reader, isolation among those capable of

caring for themselves is at present entirely unnecessary.

But while extreme measures are not called for, local health boards must

soon act in the prevention of tuberculosis. For the present the wisest

and most humane course would seem to be to attempt to secure the desired

ends rather by instruction and counsel and help than by direct and

summary procedures. There is no more pitiable spectacle in this land

to-day than that of hundreds of victims of advanced tuberculosis in

every large town who cannot be comfortably or safely cared for in the

dwellings of the poor, and yet who are always unwelcome applicants at

most of our hospitals and at many are denied admission altogether. They

are victims of ignorance and of vicious social and hygienic conditions

for which they are not largely responsible, and States and

municipalities, which are most to blame, owe them at least a shelter and

a place to die. Unquestionably one of the urgent duties immediately

before us in all parts of the land where tuberculosis prevails is the

establishment of special hospitals in which this disease can be treated

and its victims safely cared for.

And now at last remains to be spoken what word of cheer and hope our new

outlooks may have given us for those who are already under the shadow

of this sorrowful affliction. The dreams and aspirations and strenuous

labours of the students of this disease have looked steadily toward the

discovery of some definite and positive means of cure, but as yet full

success lingers beyond their grasp. The methods for the early detection

of tuberculosis which science has pointed out make it possible for

affected persons to plan such modes of life and early seek such

salubrious climates as promise a hope of recovery. We have studied

closely the ways in which the cells of the body often successfully

resist the incursions of the already seated germs, and learned how in

many ways the natural forces of cure may be sustained and strengthened.

We have learned much about certain complicating occurrences which often

form the most serious features in the progress of tuberculosis of the

lungs, and how they may be best avoided. And so to-day the outlook for

those in the earlier stages of this disease is in a considerable

proportion of cases extremely encouraging. It is no longer for us the

hopeless malady which it was earlier believed to be. It is not

necessarily a bitter losing fight upon which one enters who becomes

aware that the finger of this disease is upon him. A long and happy and

useful life may still be his if the conditions which favour his cure be

early and intelligently fixed upon, and patiently and faithfully

persisted in. The wise physician is here the best adviser in climate

and regimen, as well as in the proper selection of remedial measures,

and the earlier his counsel is sought and acted on, the brighter will

usually be the outlook for recovery.

Research in tuberculosis and the ministration of the physician should,

and generally do, go hand in hand, and no time should be lost in

bringing to the aid of the stricken what light and promise the studies

of the laboratory day by day may yield. The great and beneficent work

which has been accomplished by Trudeau in the Adirondack woods, in at

once widening the bounds of knowledge of tuberculosis and in carrying to

a successful issue in so many the varied and delicate processes of cure,

is a cheering example of what may be accomplished with persistent

devotion, by the light of our new knowledge, in mastering a malady so

long considered hopeless.

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