Dionin, C_{17}H_{17}NO(OH) (OC_{2}H_{5}HCl) + H_{2}O =
(C_{19}H_{21}O_{3}ClN + H_{2}O), the hydrochloride of the ethyl ester of
morphine.
Actions and Uses.—It is claimed that this compound acts like morphine
without producing constipation, nausea or lassitude. It is the
conclusion of some good observers that it possesses no advantage over
codeine. Applied to the eye, it causes a local vasodilation, leading to
acute conjunctival edema. Dionin is recommended to relieve pain,
especially in respiratory affections, as an antispasmodic in
whooping-cough, for insomnia and externally in the treatment of corneal
affections, conjunctivitis, iritis, etc. Dosage.—0·015 to 0·06 gramme (¼
to 1 grain). Externally it is applied in 10 to 20 per cent. solutions.
Manufactured by E. Merck, Darmstadt. (Merck & Co., New York.)