The general _causes_ of Infant Diseases and mortality may be referred

to the sudden and violent changes after birth in its tender machinery;

to weakness and injuries from tedious and laborious parturition;

delivery before the end of the ninth month; hereditary debility;

diseased parents; foul air of cities; improper food and drink; scarcity

of food and milk; ill formed nipples; the tongue tied or retracted;

errors in quantity or quality of nutriment; too long continuance of

vegetable and acescent food; foul stomach and intestines; acidity

in its stomach; errors of the mother or nurse in food, drink, rest,

exercise, excretions, passions of mind, ill temper, passionate,

hysterical, addicted to raw spirituous liquors and drunkenness;

diseased; fasting too long before the infant sucks; unwholesome milk;

adulterated milk and bread; neglect of cleanliness, and suffering the

infant to lay too long in wet cloaths; insufficient exercise, and also

too violent agitation of the infant; the ligatures, bandages, and pins

too tight, and tormenting the infant; improper positions and postures;

cold cloathing and habitations, beds, and scarcity of fuel, especially

in northern regions, and in winter; infants excretions, and especially

by the anus, defective or excessive; improper treatment and quackery

of old women and nurses, and other such medicasters, during its

illness. It is but candid also to confess, that, in numerous instances,

the causes of infantile maladies are not yet sufficiently established

nor explained.

_Convulsions, Inward Spasms, and Tetanus._ From the exquisite

tenderness and irritability of its frame, most diseases of infants,

when fatal, seem to terminate in spasms, epilepsy, and convulsions;

with which they are infinitely more afflicted than adults, and often

endure better. Inward spasms are amongst the first of infantile

maladies: it appears as if slumbering; the eyelids are not perfectly

closed, and the white bulb of the eye is partly turned upwards, and

exposed to view; the eye-lashes twinkle; there is a tremulous motion

of the muscles of the face and lips, sometimes resembling a smile or

laugh: as the disease increases, the breath seems frequently to stop;

the tip of the nose is then contracted, with a pale, sometimes ghastly

and livid circle around the eyes and mouth; it starts on any motion or

noise; sometimes it seems falling into convulsions, but on discharging

flatulent air upwards and downwards, it recovers, and relapses again

into a lethargic state. By continuance, these spasms often terminate

in some of the following diseases; hectic fever, thrush, vomiting,

diarrhœa and green feces, watery gripes, convulsions. Infants also are

sometimes subject to a locked jaw; which we have already noticed under

Tetanus.

The predisposing and occasional _causes_ of convulsions and inward

spasms are, acrid stimulus of food, acidity, or bile, or inflammation

in its stomach or intestines; general debility; the brain compressed

during parturition, hence mould shot, horseshoe head; water in the

brain; teeth cutting the gums; passions and frights of the nurse

affecting her milk, or drinking raw spirituous liquors; improper

food of the nurse or infant; scald head, excretion behind its ears,

and cutaneous rash repelled; they are usually imputed to fulness and

foulness of the stomach and intestines. Lastly, Derangements in its yet

crude machinery.

Some adult mortality, but in all probability a very inconsiderable

portion, is included in convulsions: infants are the principal

victims. The convulsive list diminishes during the latter half of

the present century: but to unravel the problem respecting convulsive

increase or decrease, requires more elaborate investigation than

preceding calculators and criticks seem to have suspected. It is

necessary to contrast the deaths by convulsions and teething with the

christenings; for if more are born, more should be expected to die in

infancy. We must also take cognizance of some other titles of London

diseases, particularly stoppage of the stomach, colick and gripes of

the guts; both which have already been under review. Besides, chrysoms

and infants, an obsolete term, denoting the deaths in the first month

after birth, is long exploded from the bills, and probably ingulfed in

convulsions.

_Dentition._ It is probable that the mortality under this head is

exaggerated enormously in the London registers, amounting to one

fifteenth part of the annual burials. Dentition usually commences about

six or seven months after birth; sometimes not before ten, twelve,

or eighteen months, and, in some extraordinary instances, not before

two years of age. These sharp bones, in piercing the tender gums,

often excite exquisite pain, restlessness, fever, flow of saliva;

the infant’s hand is frequently thrust into its mouth; it bites the

nipple; sometimes the gum is swelled at the jutting of the tooth, and

a pale spot appears at the part where it endeavours to protrude. When

dentition is out of the natural order, it is generally painful: in

the natural progress, the two foreteeth of the lower, then those of

the upper jaw; next, the two adjacent of the upper, and afterwards of

the lower jaw, cut their way. After the eye-teeth, or canine, in the

upper, and those two opposite to them in the lower jaw are protruded,

the danger of teething is generally escaped. It is only in the first

dentition, that is, under two years of age, that mortality ensues

from this source: the fatal and most frequent transition is into

convulsions. About two years of age, infants are generally provided

with twenty teeth for the purposes of mastication: and this number

remains stationary until after seven years from birth, when all the

first set are gradually and successively thrust out by others deeper

seated in the jaw bones; about the age of fourteen all are excluded;

and in adults the number is increased to thirty-two.

_Rickets._ Notwithstanding the omission of ancient authors to

discriminate this disease, we cannot believe but that, in this

instance, the same causes would in all ages have produced the same

effects. Rickets would seem by the London registers to decrease; for

in our last group of fifteen years they shrink to 104; whereas in

the thirty last years of the preceding century, ricketty deaths are

numbered at 11,415. To what cause is this decrease to be ascribed?

Does it indicate more maternal attention, and also more propriety in

suckling and rearing of infants? Is implicit faith to be placed in the

London registers, and crimination of diseases?

Rickets, one of the chronic diseases, seldom commence before three,

six, or nine months after birth, generally between nine months and two

or three years of age, and seldom or ever after five. The progressive

symptoms are aversion to motion, and to put the feet to the ground,

decrease of strength, paleness and flaccidity of the muscles, wasting

of flesh, although in many the appetite is voracious; enlarged belly,

liver, spleen, head, and joints; tumid and tympanitick abdomen;

laborious respiration; dentition later or slower than usual; carious

teeth; fetid breath; premature acuteness of genius and reason than is

natural to the years; the countenance serious and ancient; the infant

waddles in its gait, the spine and bones of the lower extremities

become crooked and deformed, the breast prominent. The earlier rickets

commence, they are more contumacious; and when chronic or fatal, are

frequently accompanied with hectic fever: they may continue several

years, and at length terminate in general bad health, atrophy, dropsy.

Should they not be checked before the fifth, or at the utmost, the

eighth year, irremediable deformity must ensue, which in females

is often the cause of distorted pelvis, and difficult labours. The

predisponent and occasional _causes_ are hereditary; weak diseased

parents or nurses; negligent nursing; not sufficient exercise nor

cleanliness; improper diet and gross food; worms; foul stomach and

intestines; scrophulous obstructed mesenteric and lymphatic glands;

diseased liver; general bad health, with hectic fever; various

causes of atrophy; difficult dentition; faulty state of ossification;

deficiency in the ossious rudiments; faults in the organs of nutrition.

_Thrush._ In the preceding century, _Canker_ was often joined together

in the London registers with Thrush; but whether it should be coupled

with this or with gangrene, or with both, I cannot determine. Thrush

is principally a disease of early infancy: it is likewise often a

concomitant symptom of some febrile and acute diseases of adults. It

infests not the young alone, but also aged persons, especially in

cold northern and moist climates, in damp situations, and in warm

rainy seasons. As an idiopathic disease of adults, it is rare in

this island. The disease generally appears first on the tongue and

roof of the mouth, in small superficial red specks, and ash-coloured

ulcers, spreading gradually over the palate, fauces, cheeks and

lips; with anxiety, restlessness, pain, difficulty of suction and

deglutition, fever, nausea, vomiting. After some time, the ulcers

form thick, tenacious incrustations, shining like lard, ash-coloured,

brown, rarely black: these crustaceous layers scale off, but, not

unfrequently, after the interval of a few days, are again renewed: the

oftener the worse: and in such cases they may be protracted weeks.

When the raw skin appears dry under the crusts after desquamation,

they are reproduced; moisture there indicates a speedy and favourable

termination: diarrhœa frequently supervenes.

In order to prevent the superfluous multiplication of symptoms

and diseases, and which are common to all ages, I have, under the

respective titles of _Vomiting_ and _Acidity_, _Colick_, _Diarrhœa_

and _Watery Gripes_, diseases so frequent and harassing in infancy,

added the discriminating marks and peculiarities in those early years.

Small pox, measles, hooping cough, croup, dropsy of the head and spine,

phthisis, hectic and atrophy, scald head, rash, worms, have each been

the subjects of preceding investigation: ruptures make a part of our

subsequent inquiry.

* * * * *

A Miscellaneous group of diseases are here associated: several of them

unconnected in symptom, cause, or cure: others are of exotic origin,

and transplanted amongst us. Mankind left exposed, without defence or

remedy, against even this small morbid host, would soon be sensible of

the calamities and scourge of medicinal ignorance: and they would be

less surprised at the incorporation of medicine with divine worship in

ancient times.

_Venereal Disease._ Three hundred years have not altogether elapsed

since the discovery of America, and the importation of the venereal

disease into the old world. Before the discovery of its antidote,

mercury, and in some inferior degree of the native Indian remedy, the

decoction of guiacum, Europe was alarmed with universal confirmation at

the rapid inroads of this disease: multitudes, of all ranks, perished

in lingering torture, under its corroding ulcers, presenting before

death hideous spectacles of cadaverous corruption and deformity.

In the last thirty years of the preceding century, 2360 deaths are

recorded under French pox, in the London bills; and even at this day,

the chart of diseases demonstrates its fatality to be infinitely

greater than medical men could suspect.

It would, in this disease, be ridiculous to inspect hospital registers,

for the purpose of either ascertaining the ages wherein venereal

ravages prevail, or the proportion of cured and incurable. Its ravages

cannot be in infancy, nor in adolescence, nor in the decline of life.

The merest smatterer in medicine knows the infallible remedy and cure I

except that in the application to particular cases, some more judgment

and dexterity is necessary. The multitudes who now perish in these

battles of Venus, are so many sacrifices either to negligence or to

indigence; or to the grossest ignorance and empiricism of licenced

murderers. There is no other disease wherein professed quackery is so

generally resorted to, or wherein its decoys are so pernicious to the

community. The great majority of these victims to seduction, pleasure,

and necessity, are in all probability amongst the swarm of wretched

and unfortunate female prostitutes; and in the male sex amongst the

lower orders: for in those of less straitened circumstances, a small

bribe to the searchers would conjure venereal mortality into sores

or ulcers, or into consumptions. Besides, were we to add to venereal

carnage the shattered constitutions, in consequence of these wounds and

scars, it would appear an object of sufficient magnitude to attract the

attention, interposition, and regulation of the legislature. In every

metropolis, especially amongst the unmarried, and in armies and navies,

it is without doubt, much more fatal to the community. Indeed, in

cities, few of the male sex, arrived at adult years, can boast of not

having been, in some giddy moment, fascinated into impure embraces.

There are two distinct genera, or species, of the venereal disease;

the Local Gonorrhœa, and what is called Confirmed Pox. The gonorrhœa

generally begins from two to six days after the infection, with

titillation of the glans, redness of the orifice of the urethra, and

oozing of mucus; which tinges the linen in spots and hardness. These

symptoms are daily aggravated with strangury, dysury, involuntary

painful priapism, and nocturnal pollution. Sometimes, though rarely,

gonorrhœa is confined to the external mucous glands about the neck or

ring of the glans. In females, the gonorrhœa affects principally the

vagina, with pain, heat, and mucous discharge; but no considerable

dysury. The lues venerea confirmata, or syphilis, commonly begins

with either one or more ulcerations of the penis, or vagina; or with

inflammation in the glands of the groin. The ulcer or chancre appears

as a red spot on the glans, or prepuce, is hot, prurient; in a few days

the top changes into a white speck, ulcerates, and, if not prevented,

gradually spreads and corrodes all around. Inflammation, or bubo in

the lymphatic glands of the groin, may either originate from previous

chancre, or without it. In this a tumour and pain is felt in the groin,

with enlargement of the glands; this tumour and inflammation, if not

checked, increases to a boil, and suppuration; but often with tedious

subsequent ulcerations, fistulas, and sanious discharge.

These are the two usual and slight appearances of gonorrhœa, and of

confirmed pox, when the infection is first applied to the genitals;

and frequently these two genera are complicated. But in both genera,

from various causes, originating from the virulence of the disease,

the intemperance of the patient, or mismanagement of his medical

pilot, many adventitious and aggravated symptoms are superadded; in

number and severity varying in different persons; several of them,

when violent and precipitate, requiring speedy alleviation; and often

to be treated as separate diseases. In the malign train of gonorrhœa

are violent inflammation and constriction of the prepuce, before or

behind the glans, or phymosis, and paraphymosis; dysury, strangury,

priapism; painful and inflamed testicles; scirrhous and indurated

testicles; chronic gleet; stricture, caruncles, and obstructions in

the urethra. Confirmed pox, in its inveterate and chronic stages,

contaminates the whole constitution; erodes the genitals, or anus;

ascends to the throat, and excites callous ulceration and dilapidation

in the uvula, tonsils, fauces, palate, nose; hence hoarse, guttural

voice, fetid breath: the patient is variously tormented with gnawing

pains in the legs, shoulders, and hand bones, which are exasperated in

bed; with chronic headach; with cutaneous eruptions on different parts

of the face, trunk, or extremities, and dry, scaly, humid, ulcerated,

red, yellow, or purple; with ophthalmy; with nodes and tumour of the

forehead, exostoses and caries of the bones; atrophy. Chronic warts

about the genitals and anus, and called by different names, porri,

crystæ, condylomata, rhagades, thymi, moræ; are generally innocuous.

The _Causes_. Infection by contact with the genitals: or the pox, when

inveterate, may be communicated by the mouth and nipples; by drinking

out of the same vessels, by touching any diseased or ulcerated part.

When inoculated by suction, it begins first in the mouth or nipples.

_Scurvy._ True scurvy is seldom or ever mentioned by any writer, before

the long voyages, first began three centuries ago by the moderns;

that is, on the discovery of the passage to Asia by the south cape of

Africa; and the discovery of America. Then, in consequence of living

long on salted and gross diet, and the want of fresh vegetables or

fruits, together with their ignorance of the cause and cure, this

disease made dreadful havock amongst naval squadrons, and the other

busy hive employed in nautical commerce. The ancient navigators, who

seldom ventured out of sight of land, or capes; and who probably

were not under the necessity of subsisting long on salted food, do

not appear to have suffered by, nor even to have known, the disease.

Hippocrates is by some supposed slightly to allude to scurvy, under the

name of large spleen; accompanied also with spungy putrid gums, and

offensive breath: it is also, though indistinctly, noticed by Pliny, as

affecting a Roman army encamped on the banks of the Rhine.

Through all the northern kingdoms of Europe, particularly in the winter

season, and in Holland, amongst those who fed chiefly on salted fish

and gross diet; who drank bad waters, and dwelt either in morasses, or

near the sea coasts, and were exposed to cold and moisture, scurvy in

the two last centuries made cruel ravages. Several armies and besieged

garrisons in Germany, intercluded from fresh vegetables; and numbers

of the new settlers in the northern colonies of America, and who

were in nearly the same predicament, were cut off by the scurvy. The

North Americans were at last taught by the Baltickers and Swedes the

sovereign benefit of substituting spruce beer, when fresh vegetables

cannot be found. The industrious Dutch made drains and canals to carry

off water, and trusted the rest of the cure or prevention to pickled

cabbages or sour crout. In the northern parts of Russia, where scurvy

is very universal, they found a particular acidulated bread and sour

drink, powerfully to resist this disease.

By these and other precautions, the scurvy is now much less formidable

on land; but at sea no other, the nervous and putrid fever not

excepted, is so inimical to navigators. On that element it is yet the

devouring monster and tyrant. In the first voyages of our East India

Company’s ships, nearly one fourth of the crews died at sea. Nautical

records teem with tragical narratives of scorbutic ravages. But at

present, the causes and the effectual antidotes, and the cure, are so

well known, that the greatest part of the lives now lost by scurvy at

sea, are either sacrificed to gross negligence, or to impolitic and

inhuman economy. The temperature of sea air is more equal than that on

land: and that it is not pernicious, we have an undoubted proof in one

of the late Captain Cooke’s voyages; wherein, with a company of 118

men, during a voyage of three years, and through all climates, from 52

degrees north to 71 south, he lost only one man by sickness.

From 1671 to 1686, the deaths by scurvy are in the London bills

9,451; but in the succeeding fifteen years, decrease to 569 only:

and throughout the present century, continue progressively on the

declension. Even of this trifling number, what proportion was

engendered at sea, or whether they all died of genuine scurvy, I cannot

decide. The theory of the last century imputed many diseases to this

specific cacoethes, as they called it; which would have some influence

on the searchers reports. In London, the lodgings are now warm and

dry, and the people in general tolerably well cloathed: animal meat

is eat fresh; vegetables, though perhaps not universally consumed in

sufficient quantity, are certainly in much greater abundance than

formerly: beer, fermented liquors, and tea, are drank by all ranks. All

these, in conjunction with exercise, powerfully resist the tendency to

scorbutic corruption.

The progressive gradations and virulence of scurvy, are distinguished

under the three following stages: the countenance becomes pale, sickly,

and bloated, with lassitude and aversion to motion, and debility, on

any exercise. But the cardinal symptom is red, spungy, enlarged gums,

from which, on being rubbed, blood issues, and the teeth begin to

loosen and fall out; the breath and urine are fetid; and, by degrees,

bruises and black spots are seen in various parts, especially the legs.

In the next more aggravated stage, the tendons at the hams begin to

contract and swell; there are pains in different parts; disposition

to salivation and hemorrhages from the gums and nose, with increased

debility and proneness to syncope. In the last and most inveterate

stages, putrid ulcers are formed, particularly in the legs, which

are swelled and enlarged; or old cicatrices of former ulcers are

dissolved, and again break out, from which issue a sanious and fetid

discharge; and within them is generated fungous flesh, in confidence

resembling a bullock’s liver. Throughout there is no fever; nor is

the disease contagious; neither are the appetite and senses impaired,

except that there is great despondency and melancholy. The predisposing

and occasional _causes_ are cold and moisture, and subsisting long on

dried, smoked, salted flesh meat or fish, without vegetables, or these

in small quantity; putrid, and also gross diet difficultly digested,

not perspirable; corrupted stagnant water; low marshy damp situations;

cold situations; the winter season of northern climates: wet cold

cloaths, beds, houses; insufficient or suppressed perspiration,

hence the corrupted animal juices are not carried off; indolence,

sedentary life, confinement, dejection of mind, melancholy; bad health;

impurities of the blood; diseases of the spleen.

_Scrofula_, Struma, King’s Evil. In the last thirty years of the

preceding century, the mortality by evil is only 2,126, in the London

bills; and throughout the present century continues decreasing. This,

however, is a very partial representation of its fatality, which in its

consequence is far more destructive. The disease seldom appears under

two years of age; commonly between three and seven, and sometimes not

until near puberty; after which its evolution and first appearance is

very rare. The children of fair hair, rosy cheeks, smooth skin, soft

delicate complexion and temperament, are more obnoxious to scrofula

than those of an opposite temperament. It is sometimes introduced by

a tumid upper lip, and chop in the middle of it; at other times the

first appearance is oval moveable tumours in the lymphatic glands

of the neck, under the chin, or below the ears. These tumours often

continue inert one, two, or more years, and without pain, until they

tend towards suppuration; and are various in size, from a walnut to

an egg, or larger. At length there is some fluctuation, ulceration,

and exudation of viscid serum, but no concocted pus; the ulcers spread

unequally; their edges are not callous; yet they are very tardy in

cicatrizing. In this way there is a succession of tumours and ulcers

during several years; the former alternately subsiding whilst the

ulcers are open; some cicatrizing, and others breaking out; and most so

in the spring season.

A Comparative View of the Mortality of the Human Species, at All Ages And of the Diseases and Casualties by Which They Are Destroyed or Annoyed. Illustrated With Charts and Tables · 第 19 / 21 段