In illustrating this disease, above all others so little understood

by the community, by the medical profession, or, in truth, by the

greatest part of the authors on the subject, I shall rather trespass

beyond the limits of a concise systematic survey of diseases. I had

long since procured the printed annual reports of Bedlam during thirty

years, from 1750 to 1780, wherein it appeared, that out of 6000

lunaticks, the deaths amounted to 1200, or 1 of 5. This information, so

far as it went, was partly truth, but it was not the whole truth; and,

in confirmation of the general proverb, I was compelled to search for

it in a well. I was anxious to extend my inquiries to a vast variety

of particulars, not one of which could be learned from the crowd of

authors, good, bad, and indifferent, whom I perused for this purpose;

from the remote era of the Greek and Roman Catholicon, the Hellebore,

down to the present time.

Chagrined with this unprofitable research, I waited upon the learned

and venerable physician of Bedlam, Dr. Monro; who, with his accustomed

liberality and affability, recommended me to his son, upon whom the

principal medical department of Bedlam now devolves; and in whom the

hereditary virtue and exalted medical reputation of the father, are

not likely to suffer any diminution. Dr. Monro, junior, introduced me

to Mr. Gonza, the apothecary of Bedlam; whose curiosity and learning

induced him to keep a private register of all the patients; and with

all which Mr. Gonza most obligingly furnished me. It is from the

records of this respectable and well-informed gentleman, especially on

the subject of insanity, that I am enabled to form all the following

Tables and data respecting a disease, wherein, except to the few

high-priests of those temples, the rest of the Esculapian train are

nearly as ignorant as the ancients; and the unenlightened mass of the

community stare with superstitious amazement as the Israelites formerly

on the epilepsy.

In penetrating this untrodden wilderness, and reconnoitering an

unexplored host of morbid foes, I shall proceed with the cautious

investigation of astronomers and natural philosophers; first to

establish the facts and phenomena previous to any deduction or

inference. From Bedlam, the largest palace and congregation of insane

in any part of the globe; and from its valuable, but hitherto dormant

archives, I shall attempt to settle all the leading and important data,

by analyzing its internal history and transactions during fifteen

years, or half a generation; which is sufficient to decide every

ambiguity nearly as well as half a century. The materials are extracted

from many volumes; they are condensed, classed, and arranged into a

concise compendium, with no little trouble and fatigue to the author.

In number, and consequently in magnitude of information, they must be

as superior to any solitary individual observations on this subject,

as the swelling flood of the Thames is to one of the thousand smaller

rills which are swallowed up in its majestic stream. In this way we

shall not be confounded with contradictory affirmation and negation,

and the clash of oracles.

The following, therefore, are the general proportions which I shall

endeavour to demonstrate, and upon them to found a multitude of others:

the comparative proportion of insane males and females; their ages;

the cured; incurable, and dead; the length of time they were insane

before admission; the mischievous; those who attempted suicide; and

the harmless; the relapses; the periods when recovery may be despaired

of; the various remote causes. Mr. Gonza had distinguished the married

and single; but in a treatise of this nature, these, and many other

minutiæ, must be omitted.

The usual number, on a general average, of patients in Bedlam is 250;

of which 110 are stationary incurables, male and female; and who remain

there until they either die, or are discharged, for reasons hereafter

to be explained. The remainder are a moving body, upwards of 200 of

whom are annually admitted, and the same number annually discharged:

the difference of males and females is very inconsiderable; in general

the latter rather preponderate. During fifteen years, from 1772 to

1787, of 2829 insane males and females, their respective ages and

numbers in each interval of life, when classed, were as follows:—Under

10 years of age, 1; from 10 to 20, 132; from 20 to 30, 813; from 30 to

40, 908; from 40 to 50, 632; from 50 to 60, 266; from 60 and upwards,

78. Of these the cured were, 934; the incurable, 1694; the dead, 230.

Of these also, the mischievous were 743; attempted suicide, 323; not

mischievous, 886; committed shocking murders, upwards of 20; relapsed,

535.

It seems necessary to be first mentioned, that I made memorandums of

all the different periods, and time elapsed, from the invasion of the

disease, or insane paroxism, to their admission into Bedlam, from one

week to one year and upwards. I do not, however, think it important to

form a distinct class, or table, of these, but merely to observe in the

aggregate, that of the patients admitted into Bedlam, the majority were

not above six months unremittingly deprived of reason; and those, in

all the intervals, from one week to six months. The second great class

were, in the intervals, from six to twelve months. After one year, and

upwards, there are comparatively very few admissions, except on the

incurable list.

The ages at which insanity predominates are obvious, and require no

comment. During the first period under 20, the greatest part of this

small group were between 15 and 20. The ages of about 300, as also

of their cures, incurables, and deaths, are omitted in the records:

fractional exactness cannot be expected: but for gross calculation

there is abundant accuracy. With respect to the cured, incurable, and

dead, I shall make a few remarks: amongst the discharged I found a

considerable number reported as sick and weak; others, and amounting

to some hundreds, as troubled with fits, or with paralytick strokes,

and some with a complication of both the latter maladies; and also

a small fragment of pregnant females; and none of these liberated

from insanity. All these I threw into the incurable list, as I could

discover very few of them ever to return back again. Many of the sick

and weak may safely be added to the dead list; being on the confines

of the grave when dismissed. The incurables likewise contain those

admitted on the incurable list of Bedlam, as well as the great mass

discharged from thence incurable, after one year’s trial.

About one of every three are reported as cured; but from them we

must subtract for relapses, which probably would sink the cured,

radically, to one of 4. The cured are reported in all the intervals,

from one month to one year. Formerly the mortality in Bedlam was

swelled by adventitious diseases, particularly the small pox and

scurvy; both of which are now prevented. Melancholy and confinement

are known to predispose to scurvy, but by an increase of vegetable

diet, this disease is no longer in the mortal catalogue of Bedlam.

The mental derangement, no doubt, must add to the mortality: numbers

discharged, as troubled with epilepsy and palsy, must have fallen into

these afflictions posterior to their admission, as they are always

an exception: and it is observed, that few are cured without the

fits also. The insane generally die of epileptick, apoplectick, and

paralytick strokes, and convulsions, of frenzy, atrophy, or nervous

tabes. If we were to add the sick and weak, the fits and palsy, I

believe lunatick mortality would be doubled; and would then be about

one of five or six. More comparatively die of the insane patients

recently admitted, than of the stationary incurables.

The greatest proportion of patients in Bedlam, especially at the

beginning, have attempted some mischief against themselves, or their

relations and keepers: in the above list there are above a score of

atrocious murderers, exclusive of suicides. There are parricides, and

butchers of their own offspring. Their mischievous acts and attempts

were in various ways, by jumping out of windows, hanging, drowning,

stabbing, shooting, tearing off their cloaths, setting fire to houses,

and several other overt acts of malignity. Some were mischievous by

open acts of violence; others by threats only. Some not mischievous

at first, have become so, and “_vice versa_;” and several reported

as not mischievous, have afterwards hanged themselves. Females, as

well as males, are mischievous; but I do not observe so many dreadful

murders committed by the female sex. By far the greater majority of

patients in Bedlam, except at temporary intervals and exacerbations,

walk peaceably about the wards: separate confinement in their cells,

strait waistcoats, or in the ferocious maniac, handcuffs and chains,

soon render them tractable and obedient: a very small number, even of

incurables, are kept as wild beasts, constantly in fetters. Some, by

time and long confinement in the incurables, and who were extremely

vicious and dangerous, become harmless, and are then discharged. From

all the variety of causes, depressing or stimulating, I perceive

mischievous or harmless. This circumstance seems to make no material

difference in the curable or incurable. Numbers who had attempted

suicide, some who had committed murders, are in the list of cured.

I also perceive recoveries after reiterated relapses; and the

prognosticks are then nearly as favourable as though it had been

the first attack. No disease is more prone to relapse: these are,

at various intervals, in different persons, from one to upwards of

twenty years, and during this period, either one or many relapses.

Multitudes of the relapses are either after being discharged cured

from Bedlam, or before they were brought there for admission. There

are some few instances, wherein the sagacious physician of Bedlam has

been deceived; and when, after apparent recovery, and the subsequent

lunatick quarantine, patients have been discharged with sound bills of

health, but on the same day have relapsed; and even before departure

from the house. They are in danger of relapses from all the causes

which give birth to insanity. From the proportion of cured and

incurable, and successive relapses, many of which at length become

incurable, we see how difficult it is, as yet, to expel this mental

usurper, and to restore chaos into order.

I do not observe so great a difference in the recovery, from either

age or cause, as might be expected: there are cured and incurable,

promiscuously at all ages; and from all the different causes, whether

adventitious or hereditary. Even from hereditary insanity, they seem

to recover nearly as well as from the less inherent causes: there are

several instances of recovery when hereditary from the parents on both

sides. In some, where the disease was entailed, it has made its first

appearance in all the intervals from puberty to fifty years of age.

I was struck with one curious instance of hereditary insanity from

both parents, in a brother and sister, and nearly about the same time;

the one twenty, the other twenty-three years of age; one of whom was

melancholic, the other maniac. There are some few instances of recovery

after one, two, or even three years pertinacious privation of reason:

some few of the incurable in Bedlam have recovered; but all these are

very rare. After only one year’s uninterrupted perseverance of the

disease, they are generally refused admission into Bedlam, except as

incurables; and of such I cannot perceive the cured above one or two

_per cent._

Many features and particulars of the insane character and history have

now been developed. But I have not yet, as in other diseases, ventured

to affix a nosological signature, or definition, and to circumscribe

the limits between the insane and the multitude of others reputed

as rational beings. In such an attempt I might probably appear as

ridiculous as the Greek philosopher in his concise definition of man.

It is not confined within the porticoes of Bedlam and madhouses: we

might find it sprinkled over the earth; not only amongst the fanaticks

of Asia, the Bonzes and Faquirs, and some of the austere cloistered

devotees of Europe; but thro’ every rank and station of civilized

communities.

Insanity has been usually described in the two extremes of mania,

and melancholia: but it is frequently of a complex nature, with

alternating exacerbations of frenzy, and of melancholy. It is termed a

delirium without fever; of which mental anarchy there are innumerable

symptoms, gradations, shades, species, and varieties: the enumeration

of which would be as infinite as the diversity of their faces and

ideas. Sometimes insanity bursts out unexpectedly, like a squall of

wind or thunder-storm: but in general the paroxism is preceded days,

weeks, or even months, by few or many of the following symptoms, which

vary in different persons; quick motion of the eyelids, redness or

wildness in the eyes and looks, restlessness, headach, vertigo, by

something unusual and different from their ordinary conduct in the

speech, gestures, actions, looks; by high or low spirits, loquacity,

or taciturnity: in some, the appetite is voracious; in others, there is

aversion to food.

On the first ebullition of frantick mania, the looks, voice, and

gestures are wild and impetuous; in many audacious and ferocious:

they are irascible, impatient, and violent on any contradiction or

restraint: they ramble with wonderful rapidity of ideas, and garrulity

of speech, from one object to another; shouting, singing, laughing:

some, transported with extacy, roam in incoherent rhapsody through

all the fairy regions of enchantment and romance: we observe maniacks

in idea personating every being and object celestial and terrestrial,

animate and inanimate. But by such numbers either attempting or

committing mischief upon themselves or others, it is evident that

the disagreeable, turbulent, malevolent, and desponding passions

do often predominate; there is more of the jarring and discordant

than of the harmonick notes and keys: some maniacks are distracted

with malevolence, antipathy, animosity, rancour, and revenge. In the

melancholia, the mind is generally rivetted upon one object and train

of thought, about which they incessantly rave or ponder: many are

cogitative, taciturn, morose, or fixed like statues: and more of this

character are said to commit suicide. Some, plunged into despair, are

haunted with all the horrors of tartarus; or even chained within the

gloomy dungeons and inexorable bars of Cerberus.

In mania the strength is prodigiously increased. In general, insane

persons endure hunger, cold, nakedness, want of sleep, with astonishing

perseverance and impunity. During the exacerbation, most are restless;

and most are costive. Some obstinately refuse all food and medicine,

and are drenched by compulsion, as horses taking physick; which at

length renders them more docile. Some, if indulged, are ravenous and

insatiable as wolves. Some melancholick, on relapses, have only a

periodical invasion of profound grief, want of sleep and appetite,

restlessness and anxiety. Many persons, universally considered as

insane, will however, at times, act, speak, converse, and reason

acutely on various subjects, until some particular mental string or

chord is touched. With respect to general prognosticks in insanity, we

have been already copious and diffuse; and shall only add, that in some

degree of mania, more favourable hopes are entertained than in gloomy

melancholy: indecency, no intermissions or remissions, epilepsy, palsy,

tabes, frenzy, are all inauspicious. The piercing and intuitive eye of

the experienced physiognomist, will also discern presages which are

concealed from ordinary comprehension and observation.

Of the predisposing and occasional _causes_ of insanity. We all know

by demonstration and reading, that one eighth part of the blood is

circulated through the head: we know the origin and distribution of its

spinal elongation, and forty pairs of nerves; its internal structure

to the most minute discernible filaments; its division into cavities

and prominences, many of them with uncouth names, and swelling the

nauseous vocabulary of anatomy. But still the latent predisposition

or frailty in the recesses of the brain, which render some more than

others liable to this mutiny of reason, on the application of remote

and obvious causes, are totally unknown. Most of the proximate causes

assigned in authors for madness, are mere hypotheses; and of no active

use to the community, or to medicine. The pretended discoveries of

the anatomical knife; and the specific gravity or levity of the brain

in scales, are equally conjectural. The great master, decypherer, and

physiologist of the intellectual functions, Mr. Locke, has here taught

us to despair, and to be convinced of the imperfection of our senses

and faculties. Literature, however, ancient and modern, abounds with

madmen and authors, especially on the intellectual operations, and

springs of sense and motion. Many other subjects yet remain to engage

our attention, and to prevent our digressing into the jaded topick of

temperaments; of original organization; or the progressive revolutions,

corporeal and mental, by age and time. This is an inexhaustible theme

for observation and lucubration.

The late Dr. Mead broached a proposition, which has been transfused

through most succeeding authors: that from sudden transports of joy,

and the exhilirating passions, more were insane than from contrary

causes: and he quotes Bedlam as an instance during the year of the

South-Sea scheme, when great fortunes were suddenly acquired and

lost. I took the trouble, so far as they are recorded, to class the

different causes of insanity; which contain nearly one third of the

whole patients during the fifteen years of our scrutiny; wherein I

do not find a single example in proof of Dr. Mead’s aphorism, but

hundreds in direct contradiction to it; as appears in the following

table of causes:—Misfortunes, troubles, disappointments, grief, 206;

religion and Methodism, 90; love, 74; jealousy, 6; fright, 51; study,

15; pride, 8; drink and intoxication, 58; fever, 110; parturition, 79;

obstruction, 10; family and hereditary, 115; contusion and fracture,

12; venereal, 14; small pox, 7; ulcers and scab dried up, 5.—I have

not time to comment upon these causes: to them may be added all the

train of exasperating passions; long attention of mind rivetted upon

one object; faults of the blood or bile, and circulation in the vena

porta; plethora in the vessels of the head; _furor uterin_; in some of

the Asiatic nations, opium; also intoxicating poisons snuffed by the

nose; “_cum multis aliis_.” The revolution of the seasons seem to have

no effect on insanity; nor are the effect of the moon conspicuous in

Bedlam.

* * * * *

_Diseases of the External Senses;_ including vision, hearing, smell,

taste; to these we shall add the diseases of the voice and speech;

obstructed deglutition; sterility, and morbid irritability of the

generative organs. The derangement of those delicate and precious

senses through which we derive such supreme delight; through whose

avenues are conveyed into man the first rudiments of all his variegated

ideas and knowledge, are important objects of medical scrutiny;

notwithstanding very few from these causes are precipitated into the

crater of mortality. I could, however, have wished to ascertain from

registers, in conformity with my general plan, the proportion of cured

and incurable; and especially the average of blind in a community.

_Vision._ The principal diseases may be comprehended under opthalmia,

fistula-lachrymalis, gutta-serena, cataract, specks on the cornea.

I exclude some other natural defects, rather than diseases, such as

myops, presbyops; for the cure of which the optician is the best

physician.

Opthalmy, or inflammation of the eyes is a frequent complaint: it

may be in the exterior membranes of the globe, or in the edges of

the eye-lids; or may be a complication of both; it may be in one,

or in both eyes; it may be general, partial, external, internal,

temporary, chronic, idiopathick, symptomatick: of all which species

there are various gradations. In this local malady there is commonly

little or no fever; but heat, pain, redness, and inflammation; the

vessels of the eyes seem gorged with blood; the anterior portion of

the tunica sclerotica, and the conjunctiva, resemble a scarlet cloth,

with impediment in vision, intolerance of light, lachrymation. In the

inflammation of the cartilaginous ring of the eye-lids or tarsus,

there is frequently some remains of small ulcerations in the sebaceous

glands. The external is by far the most frequent form of opthalmy; and,

under discreet management, is attended with trifling danger: sometimes,

however, it is followed by specks on the cornea, or callosity, and

blindness; and violent inflammation has extended to the interior parts

of the eyes and retina. In the internal inflammation of the choroid and

retina, no redness is perceptible externally; but there is excruciating

pain, headach, intolerance of light, restlessness, often delirium, in a

few instances, insanity: and if not relieved in the course of fourteen

days, there is danger of incurable blindness.

Fistula lachrymalis. In this partial inflammation affecting the

lachrymal sac and ducts, and obstructing the descent of the tears, or

superfluous moisture of the eyes into the nose, this fluid necessarily

trickles down the cheeks, and the eye is overflowed with water: on

pressure of the internal angle and puncta lachrymalia, there is a

discharge of glareous serum, by which the eye-lids, during sleep,

are glewed together. The degrees of inflammation and obstruction are

various. In the inveterate stages it may terminate in abscess, ulcers,

and caries of the contiguous nasal bone.

Gutta-serena, amaurosis; in one or in both eyes, and in various

gradations, from obscure vision to cheerless tenebrosity. To a

spectator the eyes appear nearly as in health, only that the pupil is

dilated and inanimate; the retina insensible to the rays of light, and

the iris mute, without corresponding contraction or enlargement: a

physiognomist might say, there are no sensitive emanations or magnetick

rays emitted through this mental mirror. It attacks suddenly or

gradually, and sometimes intermits; but in general it is chronic, and

always dangerous; often irremediable: sometimes it is accompanied with

headach in the anterior part over the eye-brows.

Cataract may affect one eye, but in general both: it arises from

disease or opacity of the crystalline lens obstructing the visual

rays in their course to the retina: the consistence and colour of the

lens is various, white, pearl, green, yellow; and from these the

oculist forms his prognostick: in couching the eye the pearl-coloured

is preferred: the white is too soft; the green and yellow incurable;

as is also that species wherein the strongest rays of light excite no

contraction of the pupil. Cataracts in general are gradual in their

formation; weeks, months.

A Comparative View of the Mortality of the Human Species, at All Ages And of the Diseases and Casualties by Which They Are Destroyed or Annoyed. Illustrated With Charts and Tables · 第 12 / 21 段