THE USE OF RADIUM IN MEDICINE [1]

IT has been unfortunate for the progress of the radioactive

treatment of disease that its methods and claims involve much of

the marvellous. Up till recently, indeed, a large part of

radioactive therapeutics could only be described as bordering on

the occult. It is not surprising that when, in addition to its

occult and marvellous characters, claims were made on its behalf

which in many cases could not be supported, many medical men came

to regard it with a certain amount of suspicion.

Today, I believe, we are in a better position. I think it is

possible to ascribe a rational scientific basis to its legitimate

claims, and to show, in fact, that in radioactive treatment we

are pursuing methods which have been already tried extensively

and found to be of definite value; and that new methods differ

from the old mainly in their power and availability, and little,

or not at all, in kind.

Let us briefly review the basis of the science. Radium is a

metallic element chemically resembling barium. It

[1] A Lecture to Postgraduate Students of Medicine in connection

with the founding of the Dublin Radium Institute, delivered in

the School of Physic in Ireland, Trinity College, on October 2nd,

1914

244

possesses, however, a remarkable property which barium does not.

Its atoms are not equally stable. In a given quantity of radium a

certain very small percentage of the total number of atoms

present break up per second. By "breaking up" we mean their

transmutation to another element. Radium, which is a solid

element under ordinary conditions, gives rise by transmutation to

a gaseous element--the emanation of radium. The new element is a

heavy gas at ordinary temperatures and, like other gases, can be

liquified by extreme cold. The extraordinary property of

transmutation is entirely automatic. No influence which chemist

or physicist can apply can affect the rate of transformation.

The emanation inherits the property of instability, but in its

case the instability is more pronounced. A relatively large

fraction of its atoms transmute per second to a solid element

designated Radium A. In turn this new generation of atoms breaks

up--even faster than the emanation--becoming yet another element

with specific chemical properties. And so on for a whole sequence

of transmutations, till finally a stable substance is formed,

identical with ordinary lead in chemical and physical properties,

but possessing a slightly lower atomic weight.

The genealogy of the radium series of elements shows that radium

is not the starting point. It possesses ancestors which have been

traced back to the element uranium.

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