In France Pinel was succeeded in 1810 by Jean Étienne Dominique

Esquirol (1772-1840). The influence of Esquirol was as radical for

the scientific study of the subject as had been that of Pinel for the

humane treatment of the sufferers. Esquirol threw himself into the

task of founding properly conducted asylums, and he produced in 1838

his monumental work _On Mental Diseases considered in their Medical,

Hygienic, and Legal relations_. It is the first important, rational,

scientific treatise on the subject. Esquirol abandoned the barren type

of speculation that had characterized previous works on the subject

and devoted himself to the systematic collection of data. He was able

to sketch out some of the main forms of insanity, including that now

known as ‘General Paralysis of the Insane’. This disease was finally

differentiated by one of his pupils. Another pupil of Esquirol was the

first to succeed in the training of idiots. The main school of French

alienists is descended from Esquirol. In the early forties his work

resulted in the foundation of journals and societies devoted to the

study of Insanity in France, England, the United States, and Germany.

England was behind France in her treatment of the Insane. Not until

1828 were there proper laws governing their certification. In 1844 the

great and good Lord Shaftesbury (1801-85), the seventh Earl, brought in

his Bill establishing the Board of Lunacy Commissioners with the duty

of inspecting all lunatic asylums. It was a subject to which that great

philanthropist gave much thought. The same period saw also an awakening

in the United States, where Miss Dorothea Lynde Dix (1802-87) carried

on a very successful campaign for the better treatment of the insane

and the establishment of proper houses for their reception. Her labors

resulted in the foundation of many asylums on a reformed model in the

United States and Canada. In 1845 the provision of asylums out of the

local rates was made compulsory on the local Justices in England.

The late sixties and early seventies saw in every country a further

change for the better in the treatment of the Insane. The causes of

this improvement were two. On the one hand, Insanity came generally

to be recognized as a group of diseases which, like other diseases,

have usually a traceable physical basis. On the other hand, the great

improvement of the system of nursing under the inspiration of Florence

Nightingale (pp. 298-300) began to reach the asylums. In 1877 there

was a Parliamentary investigation into the care of the Insane in

England and Wales, and in 1890 the duties of asylum administration were

transferred from the Justices to the County Councils. This has resulted

in an immense improvement in the accommodation and treatment of the

insane poor in England. At the same time the order of a magistrate

became necessary for the consignment of a private patient to an asylum.

In 1913 provision was made for the mentally defective, who do not come

within the Lunacy Act. Lastly, with the establishment of a Ministry of

Health in 1917, the general control of the Insane has passed to that

body.

Many types of insanity have been traced to an organic cause in the

Nervous System itself. The Morbid Anatomy, both coarse and microscopic,

of some of these diseases has become recognized. Chief among them is

the well-known condition known as ‘General Paralysis of the Insane’.

During the intensive study of the factors in the causation of Insanity

it has become clear that in some groups, as in General Paralysis, which

is always preceded by Syphilis, a ‘toxic cause’ is at work. Other

types of toxic insanity are due to the actual intake of a poisonous

substance. This is sufficiently evident in cases which are associated

with Alcoholism. There is also evidence that in a considerable

number of cases toxic conditions result from perversion of metabolic

processes, or, again, are associated with ‘deficiency’ states (pp.

302-8). This is a very hopeful finding, since by removing the toxic

cause, or by remedying the deficiency, relief may be possible.

Much less hopeful is the outlook with those forms of insanity,

especially common in the adolescent, which are of the nature of a

perversion of development. Such is the large group known as ‘Dementia

praecox’. These cases almost invariably originate from a mentally

unsatisfactory stock. This is less so with the Epileptic insane, though

a considerable proportion of epileptics may be classed with those

who are born mentally defective and are liable to give rise to a bad

stock. Whatever view may be taken of the question of the artificial

limitation of human fertility, it is almost impossible to imagine that

the free breeding of these classes of defectives, epileptics and their

congeners, will continue unchecked in any civilized community.

The general care and treatment of the insane has improved out of

all knowledge during the last quarter of a century. It is probable

that there is now no class of sick person who is more skilfully and

considerately cared for.

From time to time an alarm is raised at the rapid increase in Insanity,

and it is a fact that the proportion of certified insane has been,

for some time, steadily rising. A considerable part of this rise is

certainly due to the greater willingness of the insane themselves to

enter an asylum, and of their friends to allow them to do so. Part of

the rise in numbers of the insane is due to their increased length of

life under improved treatment. It must be remembered that more than 90

per cent. of the insane in England and a similar percentage in other

countries are paupers, who are not readily discharged as they have no

means of support. Mild mental cases and the senile insane go now to

the improved asylums. Before they would have been kept at home or sent

to a rate-supported or a State infirmary. The general conclusion of

those best qualified to judge is that Insanity, if increasing at all,

is doing so only very slowly.

[Illustration: FIG. 127. ‘THE RETREAT’ NEAR YORK FOUNDED IN 1792

being the first institution in England where the insane were accorded

humane and scientific treatment.]

§ 16. _The New Movement in Psychology._

During the last half-century various new points of view have entered

into our conception of Mind and its disorders. The evolutionary view

of the origin of man, which was brought to wide notice by Charles

Darwin, not only in his _Origin of Species_ of 1859 but also in his

_Descent of Man_ of 1871 and his _Expression of the Emotions_ of 1872,

has given rise to new ideas as to the nature of many instincts and

emotions. These views have been co-ordinated with our knowledge of

lower types of man, both in his existing state and in his extinct and

fossil forms. Much that we call Insanity has been found to be related

to what is normal in other and less developed environments. The Mind,

breaking free from its habitual restraints, ‘reverts to a lower type’.

There is a constant though unconscious ‘conflict’ in the mind, which is

variously resolved.

Whole schools of Psychology have arisen in the discussion of the nature

and resolution of these conflicts. Sigmund Freud of Vienna (1856-)

takes the leading place among those who have dealt with this subject.

He holds these conflicts to be rooted in sex and has introduced

the method of _Psycho-analysis_, which lays great stress on the

subconscious or unconscious element in mental life. Largely under the

direction of C. G. Jung of Zürich (1875-), preventive and curative

measures, based on this view, have been introduced into medicine.

It has been established that painful experiences, lurking in the

unconscious mind, disturb the equilibrium of health. Such disturbance

is often of the nature of a struggle to repress into the unconscious

unpleasant memories which are tending to surge up into the conscious.

The psycho-analyst seeks to release the repressed experience into the

conscious. The recognition and consideration that follow a success in

this attempt is often far less painful than the repression. Persistent

unreasonable fears on the part of adults, but especially of children,

are frequently thus dispersed.

The importance of suitable environment to children has always been

recognized. But a new significance has been given to the mental

impressions received in infancy by cumulative evidence of harmful

results in the adult life of events in the early years of life that

are seemingly forgotten. This recognition of the enduring character of

mental impressions has led to a movement for the better instruction of

mothers, and has thus been a factor in the remarkable development, in

recent years, of work for infant welfare.

It is recognized, moreover, that certain instincts--such, for

example, as the self-regarding instinct and the sex instinct--must

have expression. Mere repression of such instincts is always harmful,

but they are susceptible of a process of transformation, technically

known as _sublimation_, to an almost indefinite extent. Thus the

self-regarding impulse need by no means lead to the inconvenience and

discomfort of others, but, rightly guided, may develop into a sense

of personal responsibility for the welfare of others. So, too, sex

instinct is but one aspect of that creative vital activity on which

depends the continuance not merely of the human race but also of the

culture that the race has built up. The sex instinct is thus habitually

sublimed into other creative channels, and there are many altars,

beside those of Venus, at which young men and women may kindle their

essential fires.

§ 17. _The Revolution in Nursing._

During the Middle Ages, and in Catholic countries after the

Reformation, attendance on the sick in Hospitals and elsewhere was the

task of religious sisterhoods. In Protestant countries the absence of

these sisterhoods necessitated the employment of women specially for

the purpose. The task was not an attractive one, nor did any social

distinction attach to it. The profession of nurse became despised

and was followed, for the most part, by a low and illiterate type of

woman, though midwives were sometimes better educated and of a higher

class (p. 180). The great philanthropists of the eighteenth century

(pp. 171-72) could do little to improve the nursing profession.

The conditions of employment formed the root of the evil. The vast

improvement that has resulted in health and happiness to our whole

population from the improvement in the character and training of nurses

is probably seldom realized, even by medical men. Yet it may reasonably

be doubted whether all modern medical and surgical advances put

together--apart from Preventive Medicine and Infant Hygiene--have saved

as many lives as the Reform of Nursing.

The reader may gain some insight into the life of a nurse from the

conditions that prevailed until beyond the middle of the nineteenth

century at a very good and well-managed English provincial hospital,

the Radcliffe Infirmary at Oxford. The salary of a nurse was £5 a

year. There was no distinction between a nurse and a domestic servant.

One nurse only was the allowance for a ward of seventeen patients. A

nurse’s day began at 6 a.m. The wards were cleaned till 7, when a bell

was rung and each nurse had to bring down her ashes and sift them under

the direction of the porter, who then gave her coals for the day. She

took breakfast with the patients, who helped her, so far as they were

able, with the ward work. At 2 p.m. she went to the servants’ hall,

where she had her dinner in company with the servants on daily hire.

During the dinner the ward was left in charge of a patient. After

dinner she took away a plate of meat and vegetables for her supper. For

the night there was normally only one nurse for the whole hospital of

about 100 beds. There were no regular holidays, and the nurse was never

allowed to leave the hospital before 6 p.m. The practice of nurses

receiving gratuities from patients continued till 1870 and even beyond.

Those patients who wished to secure a nurse’s early attention for their

dressings gave tips, those who did not frequently had to wait.

What sort of woman could such a system produce? That some nurses at

least were kind and skilful, even under such conditions, is a fact, and

is pleasing evidence of the natural goodness and wisdom that reside in

the human heart. Many, however, can have been no better than Sairey

Gamp and Betsy Prig.

The first important reform in Protestant countries began in Germany,

through the influence of Elizabeth Fry (p. 171). In 1822 Theodor

Fliedner (1800-64), the young pastor of the church at Kaiserswerth, a

little town on the Rhine near Düsseldorf, visited England and was much

impressed by Elizabeth’s teaching and example. Returning to his charge,

he devoted himself to the spiritual and physical care of jail-birds. In

1833 he and his devoted wife Frederica (1800-42) opened a refuge for

discharged female convicts. From them the couple turned their attention

to the sick poor. The conception of an organized body of specially

trained women crossed their minds. In 1836 they opened a small hospital.

At this hospital six young women of the most spotless character were

induced to serve as ‘deaconesses’. It was their duty to perform all

the tasks of the hospital in rotation. The physicians who attended the

hospital gave them instruction. The Kaiserswerth idea rapidly spread

and the ‘Kaiserswerth Deaconesses’ became and remain an important

order, which is still occupied in good works in many parts of the

world. The conception of the order is different from that of most

religious orders in that the members make no attempt to withdraw from

the world, and marriage is not forbidden to them. Moreover, the duties

of the Kaiserswerth deaconesses are rather different from and more

varied than those of a sick-nurse. They include teaching, both secular

and religious, nursing, household duties, management of children and

convalescents. In 1865 a preparatory school for probationers was opened.

In England Anglican orders of a somewhat similar character were formed

in the forties and fifties. In 1850 and 1851 Florence Nightingale

(1820-1910), who was a lady of good social rank, visited Kaiserswerth,

and went through a regular training there. She was profoundly impressed

by the extremely high character of the deaconesses, most of whom were

only peasant women. The next three years she spent in writing and in

examining hospitals in her own country.

Florence Nightingale’s opportunity came with the outbreak of

the Crimean War in 1854, and the rapid breakdown of the medical

services, which contained no women nurses. The French had a number

of ‘religieuses’ to nurse their sick, and a feeling of shame arose

in England at the neglect and mismanagement of the British sick and

wounded. The Secretary of State for War asked Florence Nightingale to

go to the Crimea to organize a nursing service. She left at once with

thirty-eight nurses whom she selected personally. Ten of these were

Roman Catholic sisters and all the others had had nursing experience.

From that event dates the Revolution in Nursing. Florence Nightingale

performed marvels under conditions of great difficulty (Fig. 128) and

in the face of determined opposition. She returned home in 1856 a

national heroine. She had no difficulty in establishing a school and

home for nurses at St. Thomas’s Hospital in London in 1860. The example

was followed by the other London hospitals.

Florence Nightingale was a woman of the most powerful will and an

admirable organizer and administrator. Her system of nursing contained

many new features, not quite all of which have stood the test of time.

That nursing rapidly and steadily improved from the moment she was in

authority cannot at all be doubted. Looking back, it is apparent that

the immediate success of her methods was due to two main factors. First

was her capacity to secure women of high character and good social

position to accept positions of responsibility. Second was her removal

of the control of the nursing staff entirely from the hands of men into

those of women. Her influence soon passed across the Atlantic, and she

was associated with the United States Sanitary Commission and the women

who took charge of army nursing during the American Civil War.

While Florence Nightingale was reforming Nursing, her contemporary,

Mary Carpenter (1807-77), was applying herself to the kindred task

of looking after neglected children, establishing Reformatory and

Industrial Schools and improving the position of Indian women. She

obtained a large measure of public support and exercised considerable

influence in America, which she visited in 1873. Many other

distinguished and devoted women worked on similar lines.

Among the indirect results of the activity of Florence Nightingale was

the establishment at Geneva in 1864 of the International Red Cross

Committee, the branches of which have done good service in many wars

and have been no less useful in peace.

Florence Nightingale opposed anything in the way of State registration

of nurses. Concentrating on a high ideal of competence and character

for the nurse, she failed to grasp some of the secondary effects of

her own scheme. A large nursing service is now a necessity in every

civilized country, as a result of her efforts and example. Having

regard to human imperfections, we can as little hope that every woman

who nurses will be a born nurse, devoted to her task, as that every

doctor or teacher will have a natural vocation for his work. In an

imperfect world mankind must protect itself against the incompetent and

the unfit. Registration is a way--doubtless an imperfect way--of doing

this. A Nurses’ Registration Act became law in England in 1919.

There have been many improvements in the details of the training of

nurses, incident on the changes in Medicine and Surgery during the last

half-century. Apart from these, the main improvements in Nursing have

been due firstly to an increased interest in the welfare and health

of the nurse herself, and secondly to the recognition that Nursing is

a profession for which, as for Medicine, some preliminary scientific

knowledge should precede professional training. Thus, the very long

hours of the nurse have of late been reduced, and in the best schools

instruction is now given to nurses in Anatomy, Physiology, Hygiene,

Bandaging, and Cookery, before the commencement of actual hospital work.

Further developments will probably be along the lines of State and

Municipal Nursing Services. Since Health is a public as well as a

private concern, the same must be true of the training and work of

nurses.

[Illustration: FIG. 128. FLORENCE NIGHTINGALE RECEIVING WOUNDED AT

SCUTARI

_From a painting by Jerry Barrett_]

§ 18. _Some Modern Physiological Concepts of Clinical Import._

The vast activity in the sciences of Physiology and Pathology during

the last fifty years, and their repeated divisions into independent

sciences, each prosecuted by its own specialists, have yielded many

ideas which have been imported into the clinical practice of Medicine.

It is impossible to say which of these are of permanent value. All

previous ages have had to discard part of the practice and a large

proportion of the medical ideas that have been handed down to them, and

there is no reason to suppose that the age that follows us will differ

from those which have gone before us. Some ideas that have entered

Medicine from the physiological laboratory, pushed by interested

parties or seized on in despair by physicians at a loss for a line of

treatment, are already seen by men of experience and judgment to be no

permanent addition to our store. Other lines of physiological thought

are still under discussion by them.

There are, however, certain physiological conceptions which, apart from

their general implications in the economy of the body, have received

such wide application that their future, as an organic part of medical

practice, seems assured. Certain of these conceptions demand discussion

in even the most cursory survey of medical development.

(a) _Ductless Glands and Internal Secretions._

The nature and action of the various glands of the body has been a

classical physiological field. Malpighi (pp. 116-20) was the first to

investigate the structure of these organs, and he was followed by many

others. It became evident that many glands, such as the liver, the

salivary glands, and the tear glands, are provided with ducts or tubes,

which carry off the characteristic secretion of the glands. These

secretions can be examined with comparative ease--as happened early

with the secretion from the stomach, or ‘gastric juice’ (pp. 146-48),

and later with the secretion of other glands. There remain, however,

certain glands unprovided with ducts. The action of such ‘ductless

glands’ long remained a mystery. Of these the type is the ‘Thyroid

gland’. Much of our physiological knowledge of this organ, together

with the conception of its function as indispensable to normal life,

has come through Surgery.

It had long been known that certain symptoms were associated with

enlarged Thyroid gland or ‘Goitre’. Attempts to remove the organ

surgically were made after the introduction of antiseptic methods.

Goitre is particularly common in Switzerland, and it is not remarkable

that the technique of the very dangerous operation for the surgical

removal of goitres was first perfected by Swiss surgeons, among whom

Theodor Kocher (1841-1917) has taken the first place. The study of

cases that had had their Thyroid glands removed gave a clue to the

nature and action of the gland.

It was found that those surgically deprived of the Thyroid gland

develop abnormal slowness in movement and response. The temperature is

low, the pulse small, the muscles are torpid and sometimes rigid, and

there is a failure in ordinary fine muscular movements. The patient

shows a thickening and swelling of the skin and presents a dull and

very characteristic appearance. When the operation was performed on

one whose growth was not yet complete, development was checked. Such a

patient remains infantile or childish both in body and mind.

The conditions were recognized by Swiss surgeons in the seventies

as resembling those of a spontaneous disease to which the name

_Myxoedema_ was attached. Further the close relationship both of the

surgical and of the spontaneous condition to the state of idiocy known

as _Cretinism_ came gradually into view. In Switzerland, as in other

parts of Europe, stunted beings known as _Cretins_ had long been known.

These defectives are sometimes goitrous, sometimes without a Thyroid

gland, but their general appearance and condition is an exaggerated

version of what has been described for those with Thyroid glands

removed (Fig. 129).

[Illustration: FIGS. 129 and 130. CRETINOUS INFANT BEFORE AND AFTER

THYROID TREATMENT.

_From the Collection of the Royal College of Surgeons._]

The result of these observations was to direct the attention of

physiologists to the Thyroid gland. It was soon found that the symptoms

of Thyroid deprivation could be experimentally produced in animals.

Moreover, it was shown by Moritz Schiff of Berne (1823-1890), in

1884, that the results of the removal of the Thyroid might be avoided

if the animal were fed regularly on an extract of the glands. The

results were soon applied to man and have led to one of the greatest of

medical triumphs. By its means sufferers from myxoedema and cretinism

can be either cured or improved. A drivelling and idiotic cretinous

child, adequately treated with Thyroid, enters on a normal process

of development. The improvement is almost incredible, and the child

rapidly passes into a healthy and happy state, so that it is literally

true to say that his own parents would not recognize him (Fig. 130).

Further, the gland may be given in excessive doses, and a condition

produced that closely resembles a well-known pathological condition

known as ‘Exophthalmic Goitre’, which is similarly susceptible of

experimental investigation.

The facts here enumerated justify the deduction that the Thyroid

gland secretes something which is essential to normal well-being. The

organ has no duct, and the secretion is, therefore, never normally

thrown out of the body. The Thyroid is, in fact, an organ of what is

called ‘internal secretion’. Investigations on this secretion led to

the isolation of the active principle as a pure compound known as

_Thyroxin_ in 1916. The story of the Thyroid has recently (1926) been

rounded off by the preparation of Thyroxin synthetically. The synthetic

product has been given with effect in cases of Myxoedema.

A short history of medicine · 第 18 / 23 段