The eighteenth century was essentially a period of individual effort.

The time was not yet ripe for public action on a large scale in

matters of Hygiene. Pringle, Lind, and Percival had, however, their

humanitarian parallels among prison reformers. Scientific attempts to

improve the ventilation and sanitation of prisons had been instituted

by the Rev. Stephen Hales (pp. 146-7). None brought greater devotion

to the task than John Howard (1726-90), a native of London who spent

his vigorous powers in investigating the prison system. His researches

extended to the hospital, quarantine and prison systems of France,

Flanders, Holland, Germany, Italy, Greece and Turkey (Fig. 88). His

reports were directly instrumental in the improvement of the hygiene

both of prisons and hospitals, as well as in the institution of

special fever hospitals in many countries. Some aspects of Howard’s

work were carried on by the great Quaker philanthropist Elizabeth Fry

(1780-1845), others came within the field of activity of Southwood

Smith and Chadwick (pp. 193-5).

The eighteenth-century humanitarian movement was active and had many

able representatives in the United States. Foremost among them was

Benjamin Franklin (1706-90), while in the ranks of Medicine none takes

a higher place than Benjamin Rush of Philadelphia (1745-1813). Rush

was particularly revolted by public punishments, to the abolition of

which he devoted much energy. In matters of Hygiene Rush was ahead of

his time. He wrote on the hygiene of troops and laid special stress

on fresh air and cleanliness of body and mind as an aid to health. He

had a peculiar horror and repulsion for alcoholic intemperance. He

was responsible for the first systematic work on insanity published

in America. He left a fine account of a Yellow Fever epidemic at

Philadelphia, and he approached the truth in his view that the disease

arose in Philadelphia itself and was not brought as an infection from

without.

[Illustration: FIG. 88. AN EIGHTEENTH-CENTURY QUARANTINE STATION

(Naples).

From John Howard’s _An Account of the principal Lazarettos in Europe_,

Warrington, 1789.]

§ 11. _The Industrial Revolution._

During the eighteenth century the character of English civilization

became modified by a factor which has since profoundly influenced all

civilized countries. There was a rapid increase in the number and size

of the towns. The main cause of this was the transformation of Industry

by the use of mechanical power. The change that resulted in the life

and outlook of the people was very profound. These changes and the

causes that gave rise to them are usually spoken of as the ‘Industrial

Revolution’. That revolution had effects that were both wider and

deeper than followed any other such single upheaval in history. With

the mechanical elements that were at the back of the Industrial

Revolution, such as the improvements in transport, the invention of

industrial machinery (Fig. 90), the enclosure of common land, the new

position of agriculture, we are not here directly concerned. What does

affect our story is the increasing urbanization of the population,

which began early in the eighteenth century, increased rapidly soon

after the middle of the eighteenth century, and has progressed

continuously ever since. In this matter England is but a type,

for all other civilized countries followed in her wake, though at a

somewhat later date.

Along with the growth of towns and the increased population there was

an increased demand for food. The country became better cultivated and

better drained, and there were many improvements in agriculture. Thus,

certain diseases began to diminish, notably Malaria, essentially a

disease of undrained and ill-cultivated lands. The expulsion of this

disease, as of Typhus, was the work of the nineteenth century (p. 283).

It is often assumed that the physical evils of life became accentuated

by the rise of the great towns. Nevertheless, investigation shows

that the opposite has been the case. During the eighteenth century

men and women began to crowd into the great towns from the country.

They were, in fact, right in their choice, for their chances of life

there were greater than upon the land. In the rural districts infamous

housing conditions, an overcrowding beyond anything which we now

encounter, exposure to weather, uncertainty and fluctuation in the

prices of commodities, low wages, unpassability of roads in winter

time, inaccessibility of medical aids, combined to render life, and

especially child life, more precarious than in urban areas.

[Illustration:

FIGS. 89 and 90 illustrate the passage of the textile trade from home

industry to factory work with the consequent break-up of the family as

the labor unit. Textiles were the first important articles of commerce

to be thus affected, but others rapidly followed. The pictures are

typical of the Industrial Revolution.

]

The improvement of hygienic conditions in the towns began in England

soon after the middle of the eighteenth century. Westminster obtained

an Improvement Act in 1762, Birmingham in 1765, the City of London in

1766, Manchester in 1776, and most of the other provincial towns soon

followed. As a result of such Acts noisome streams which were but open

drains were covered in, the streets were paved and lighted, and the

sewers improved. There were still many glaring defects of sanitation

which have occupied and still occupy reformers, but by the end of the

eighteenth century the general appearance of a street in one of the

more advanced cities was much what it now is. The change from the

medieval conditions of a century before was at least as great as the

changes that have since taken place.

[Illustration:

FIG. 91 shows how the population of England and Wales started to

increase rapidly about 1750, with the beginning of the Industrial

Revolution. The chart covers a period in which statistics were not

exact. The figures for it have had to be estimated, but they are

probably accurate as round numbers. The census returns are available

from 1801.

]

[Illustration:

1910-12

_Age_ 1730-9 1740-9 1750-9 1760-9 1770-9 1780-9 1790-9 _Males_ _Females_

10 36·9 37·0 37·3 36·9 36·7 37·5 38·2 -- --

20 29·1 28·9 29·2 29·3 29·4 29·9 28·4 42·35 46·71

30 23·7 23·5 23·8 24·1 24·1 24·9 24·4 33·87 37·94

40 19·6 19·2 19·4 19·6 19·5 19·5 19·5 26·03 29·67

50 16·1 15·8 15·7 16·1 15·9 15·7 15·8 19·09 22·17

60 12·2 12·4 12·1 11·9 11·9 12·0 11·9 13·09 15·39

70 9·4 8·6 8·7 8·5 8·3 8·7 8·5 8·17 9·57

80 5·9 5·7 5·7 5·7 5·7 6·3 6·2 4·79 5·39

Showing the expectations of life in London for each decade from

1730-1800, with recent data for comparison.

_Age_ 1730-9 1740-9 1750-9 1760-9 1770-9 1780-9 1790-9 1911-12

10-20 6·5 5·9 5·9 7·1 8·2 7·1 6·5 --

20-30 17·5 17·6 17·2 17·9 17·3 16·4 15·1 3·7

30-40 27·1 26·3 26·1 25·2 25·0 23·9 23·7 6·2

40-50 36·6 38·6 35·9 36·3 35·5 35·4 34·3 11·7

50-60 45·5 47·9 45·7 42·1 45·0 44·7 44·6 21·1

60-70 61·4 63·4 63·7 64·4 62·8 64·7 64·1 40·3

70-80 83·7 98·3 96·4 101·8 105·0 101·7 104·4 87·3

80-90 143·1 150·4 151·0 153·0 152·7 153·0 155·1 181·9

Showing the death-rates at Age groups in London for each decade from

1730-1800, with recent data for comparison.

FIG. 91A. TABLES showing that vital conditions in the eighteenth

century did not deteriorate but improved with the Industrial

Revolution. ]

But if the streets had improved there was much under and around them

which would horrify us now. Water-supply, as in London, was usually

drawn mainly from surface wells and rivers. In most towns a continuous

water-supply was unknown. Even when water mains existed, the supply

to the houses was limited. Thus, even in the early nineteenth century

London houses had a water-supply only three times a week, and then only

for a few hours at a time. The water mains were often defective, and

there was not always that clear distinction between a water main and a

sewer that we now regard as desirable. Floods were a constant trouble

in all riverside towns. Cesspools were in use even in London as late as

the middle of the nineteenth century, and water-closets did not become

general, even in the better houses, until about 1828. The methods of

disposal of sewage hardly bear relation. In London the sewage simply

polluted the rivers.

The improvement of such conditions as these could only be made by State

action. The eighteenth century did well where individual activity

was concerned. It was reserved for Southwood Smith (p. 193) and

Chadwick (p. 194) to introduce into the sphere of practical political

action the truth, set forth by Bentham (pp. 190-2), that all factors

which influence the health of the country must be the concern of the

Legislature.

We gladly pass from this darker picture to the Hospital and Dispensary

Movement which took its rise about the middle of the eighteenth

century. Many of the great hospitals both in England and in Continental

countries were either founded or rebuilt about this time. Thus, the

London Hospital was rebuilt in 1752, St. Bartholomew’s in 1730-53.

Between 1700 and

1825 no less than 154 hospitals and dispensaries were founded in

the British Isles. Though defective from the modern point of view,

yet under the influence of the sanitary reformers, Hales (p. 146),

Pringle (p. 169), Lind (p. 170), and Percival (pp. 170-1), these were

incomparably better equipped, better ventilated and better found than

such institutions would have been at the beginning of the eighteenth

century. The notes of the industrious Howard (p. 171) give us a very

complete picture of them, and one that is more favorable than might,

perhaps, have been expected.

A defect of the hospitals of the time was certainly the nursing.

This, however, was somewhat better in the Lying-in-Hospitals, where

the services of a higher type of woman were available and where

ladies served on the committee of management. The general state of

the hospitals remained much the same until transformed by the changes

in surgery and nursing in the second half of the nineteenth century,

though a number of special fever hospitals and pest-houses were

established.

Something must be said of the more prevalent diseases of the Industrial

Revolution. Stress is often laid on the effect of urban conditions

on child life. Yet there can be little doubt that historically the

movement has been beneficial to it. This comes out well in the

death-rates. Thus, in England in the period around 1740, before the

industrial revolution had begun, about 75 per cent. of children born

died before the age of five. In the period around 1800, when the

industrial revolution had set in, the percentage of deaths had fallen

to about 41. In the period 1915-24 it was about 14. Among the most

characteristic diseases of children is Rickets. It is very difficult

to trace the early history of this disease, but its incidence seems

to have been very high about 1700, and to have fallen progressively

throughout the eighteenth century. This fall, it has been suggested,

was due to agricultural improvements which led to better supplies of

better-fed meat. It was these improvements and better supplies that, in

their turn, made the big towns possible.

We have already spoken of Scurvy on ships. It was, however, well known

on land, especially in winter when green vegetables were not to be

had. Lind (p. 170) in 1753 found it common in the land population. The

advances in agriculture removed it altogether from the land diseases

during the eighteenth century.

[Illustration: FIG. 92. ST. BARTHOLOMEW’S HOSPITAL AT SMITHFIELD,

LONDON, in 1720.]

[Illustration: FIG. 93. A VIEW OF THE PEST HOUSE in Tothill Fields,

London, in 1796. From a print in the British Museum.]

§ 12. _Control and Recognition of Epidemic Diseases._

Over one department of public health there was State supervision

during the eighteenth century. The ports were guarded against the

introduction of Epidemic Diseases, and especially against Plague.

Throughout the eighteenth and early nineteenth century there was Plague

in the Near East which extended at times to various parts of Europe.

It was epidemic in Russia in 1709 and some 150,000 died of it. In 1719

it spread to Eastern Central Europe. One historic outbreak was at

Marseilles and Toulon in 1720, when 90,000 died. The outbreak caused

great alarm in England, but did not reach this country, nor has there

since been any outbreak here. Quarantine is now regarded as antiquated,

vexatious, inhumane, expensive, and ineffectual. It seems probable,

however, that during the eighteenth century, when drastically enforced,

as in France with the Marseilles epidemic, it had indeed the effect

of keeping the disease within bounds. Incidentally, it led to the

foundation of many plague hospitals or Lazarettos, of the conduct of

some of which Howard (p. 171 and Fig. 88) speaks well.

During the eighteenth century Small-pox was never absent from this

country. From time to time the disease became epidemic, and there

were grave and fatal outbreaks. Thus, in 1774 there was an outbreak

of small-pox at Chester. Next year an investigation was made of the

degree to which the population had suffered. It was then found that

before the outbreak there were in Chester only 15 per cent. who had

not already had the disease. The incidence on those unprotected by a

previous attack was 53 per cent., with a death-rate of about 17 per

cent. of those actually infected and of about 9 per cent. of the entire

unprotected population.

With the certainty of contracting small-pox before their eyes, men

sought a way of getting it in a mild form. Outbreaks of small-pox

varied greatly in virulence, and infection with a mild form would

lead to protection from a graver one. In the East a method of direct

inoculation of the disease from a patient suffering from a slight

attack was widely in vogue from an early date. The practice attracted

little attention in Europe until Lady Mary Wortley Montagu (1689-1762)

studied it at Constantinople. It was then soon taken up in England, and

became recognized on the Continent.

The efforts of Lady Mary in England were reflected on the other side of

the Atlantic. The famous Puritan leaders, Increase Mather (1639-1723)

and Cotton Mather (1663-1728), turning from their exploits against

the witches, ardently urged the operation. In England the learned

Dr. Richard Mead (1673-1754), an eminent and far-seeing physician

who exercised very great influence on the medical world in his day,

published in 1747 a work in which he supported the practice of

inoculation with all the weight of his authority. During the subsequent

half-century the practice spread widely. The operation was largely in

the hands of specialists who were not always medical men.

Such was the state of affairs when the country practitioner Edward

Jenner (1749-1823) came upon the scene. In 1796 a dairymaid became

infected with a disease of the udders of cows, distantly resembling

small-pox. She developed pustules on her hand. Jenner inserted a

little of the matter from one of these into the arm of a boy of eight,

who developed typical cow-pox. Jenner next inoculated this boy with

small-pox, which, however, failed to develop. The evidence, so far as

it went, was complete. It is an entire justification of what might seem

nowadays to be a reckless experiment, that at that time inoculation

of small-pox was a normal and effective defensive procedure. The

disease of cows has since become known as Vaccinia, and the process of

inoculating it as _Vaccination_.

[Illustration:

FIG. 94. HAND OF DAIRYMAID infected with cow-pox from a cow’s udder.

From Edward Jenner, _Inquiry into the Causes and Effects of the

Variolae vaccinae, a Disease discovered in some of the Western Counties

of England, particularly Gloucestershire, and known by the name of the

Cow Pox_, London, 1798.

]

The discovery of vaccination, important though it be, is a mere

trifle compared to the train of new work and new thought that has

been opened out by it. The whole study of Immunity, which has now

become an independent science, arises from it. The work of Pasteur (p.

225), Lister (p. 239), and Koch (p. 234), and a large part of modern

therapy, are among the achievements of this movement.

Besides Plague and Small-pox, many other epidemic diseases became more

clearly understood during the period we are considering. Among these

was Scarlet Fever, the history of which is particularly interesting

for the variations which it has shown in virulence. It first became

clearly recognizable as a mild disease without prominent symptoms about

1650. Good observers in the half-century that followed considered it a

new disease. In England it continued to be of little importance till

about 1748, when it began to be associated with grave throat symptoms

and to be confused with Diphtheria. This phase continued for about ten

years. The virulence then dropped and the disease continued of slight

consequence till 1785. It then grew virulent again and remained so till

about 1808. The malignancy then fell again and remained low for about

thirty years. It rose about 1837 and from then till 1884 it was one of

the great killing diseases, especially of childhood. Since then, the

mortality from it has steadily decreased.

During most of its history Scarlet Fever has been liable to greater

or less confusion with Diphtheria. The clinical distinction was first

clearly made in 1826 by Pierre Bretonneau of Tours (1771-1862), who

gave Diphtheria its present name. The same French physician performed

the first successful tracheotomy in a case of Diphtheria. He is also

known for pioneer work in the recognition of Typhoid Fever.

VI

PERIOD OF SCIENTIFIC SUBDIVISION

(FROM ABOUT 1825 ONWARDS)

§ 1. _Origins and Implications of Scientific Specialization._

We have seen how the philosophy of Newton, with its implication, the

Reign of Law, which is the Uniformity of Nature, has come to pervade

scientific thought (p. 137). Now, before Newton as after him, there

were certain natural divisions of scientific activity corresponding,

in some degree, to the types and faculties of men. Since Science

first began there have been Mathematicians, Biologists, Physical

Experimenters, because in fact the particular powers which enable

a man to reach distinction in one of these departments are of less

value in the others. Until the period of which we are now to treat,

investigators were accustomed to explore at large within these great

departments. Such specialist professions as Actuarial Calculators,

Economic Entomologists, Physical Chemists, or, in the department

of Medicine, Medical Statisticians, Aural Surgeons, or Vaccine

Therapists--familiar to us now--were unknown and undreamt of then. This

subdivision is a new thing, and is a characteristic product of the

period of which we have now to treat. The subdivisions, unlike those

of old, are largely artificial. Thus, the Aural Surgeon who deals with

the organ of hearing cannot be separated clearly by his training, his

powers and faculties, his operative skill, nor even perhaps by his

field of work, from the Stomatologist who deals with the mouth, or

the Rhinologist who deals with the nose. Nevertheless these minute

subdivisions are convenient and beneficent in medical as in other

departments. The question of scientific specialization is so important

and characteristic that we must examine it a little farther.

It is often thought that, since no man can compass all knowledge,

this scientific subdivision is merely an attempt to compass a part

of that growing mass of knowledge which is becoming progressively

less compassable in its entirety. The movement, however, both in

origin and development, is less simple than this, for there never

was a time when a man could know all that was known about his world.

In this respect our own age is even as other ages. Were the view

philosophically tenable--which it is not--that Science becomes yearly

less comprehensible, our outlook would be gloomy indeed. For since

there is no evidence of any increase in the mental capacity of the

human race--at least in historic time--such a view would imply a

progressive diminution in the number of those competent to treat any

wide scientific area, and a corresponding progressive separation

from each other of minds with scientific insight. Fortunately such

conditions do not prevail; the view that they do is simply due to a

gross, yet widespread, misconception of the nature of Science.

Equally fallacious is the idea, which has become diffused by the

existence of scientific specialization itself, that the progress of any

science is to be measured by the mass of observations that its votaries

have succeeded in accumulating. This is far from being the case. The

advance of a science is measured by the degree with which it succeeds

in bringing a multiplicity of observations under general laws. Judged

by this standard, we should probably rate very highly, for example,

the present state of what is called _Demography_, the study of the

life conditions of communities, while we should rank much less highly,

for example, the present state of the study of Aural Surgery. Yet, for

one publication on Demography there must be many on Aural Surgery.

In the one case, however, the accumulation of knowledge follows a

well-directed and rational scheme. In the other it is prompted and

occasioned by the immediate needs of individual sufferers. This must

not be considered as derogatory to those whose task it is to treat

the sufferers. The point is that the one department, of its nature,

exhibits the rational spirit better than does the other.

Since Rational Medicine is the subject that we treat here, we shall

select for discussion those departments which best illustrate

its spirit. This does not imply, and is not meant to imply, any

belittlement of the less fortunate departments. On the contrary, the

less any scientific department has succeeded in eliciting general laws,

the more necessary it is that those most capable for the prosecution of

such advance should devote their attention to that department. It may,

indeed, reasonably be urged that a leading defect in our scientific

organization is that men of scientific insight crowd to just those

studies where their special powers have already been best exhibited.

In previous chapters, dealing with more remote times, we have been able

to place our facts in historic perspective. Despite the enormous mass

of scientific literature dating from the seventeenth, eighteenth, and

early nineteenth centuries, there is no real obstacle to selecting

what is most important in it. True, it is beyond the power of any

one student to examine all this literature at first hand, but it has

been arranged and indexed, posterity has passed its verdict, and the

historian can find his way through the thicket. It is also true that

important advances are sometimes forgotten, as happened to Mayow’s

discovery of Oxygen in the seventeenth century (pp. 126, 151), which

was repeated by Priestley a hundred years later (p. 154). But the

fact that we know of such neglected discoveries shows that, however

unjust the fates may have been to Mayow, yet his influence has not been

underestimated by later historians. The History of Science, therefore,

can up to a certain point be written along the same lines as political

or economic history.

The face of affairs changes, however, when we pass into a period which

differs for different topics, but may be roughly defined as beginning

somewhere between about 1820 and about 1870. We then begin to encounter

the very questions with which men of Science are occupied in our own

time. Since many of these questions still remain unsettled, it is

impossible for the historian to say with certainty which are the most

fruitful lines of work. The most he can hope to do is to distinguish

the most influential and stimulating thinkers and observers from those

who have been less so, and to say something about the ideas with which

the more important schools of thought were instinct.

A short history of medicine · 第 11 / 23 段