123. The Life-History of the Parasite of Malaria.

[Illustration: HIPPOCRATES

Ἢν γὰρ παρῇ φιλανθρωπίη πάρεστι καὶ φιλοτεχνίη.

Where the love of man is, there also is love of this Art.

Παραγγελίαι, i.e. _Precepts_ (Hippocratic Collection), § 6

]

A SHORT

HISTORY OF MEDICINE

INTRODUCING MEDICAL PRINCIPLES TO

STUDENTS AND NON-MEDICAL READERS

BY

CHARLES SINGER

M.A., M.D., D.LITT., OXFORD

FELLOW OF THE ROYAL COLLEGE OF PHYSICIANS OF LONDON

LECTURER ON THE HISTORY OF MEDICINE

IN THE UNIVERSITY OF LONDON

Scire potestates herbarum usumque medendi

Maluit et mutas agitare inglorius artes

_It was his part to learn of the power of Medicine

and of the manner of healing and, heedless of

glory, to exercise that quiet art._

Virgil, _Aeneid_ xii, 396-7

NEW YORK

OXFORD UNIVERSITY PRESS

AMERICAN BRANCH

1928

COPYRIGHT, 1928

BY OXFORD UNIVERSITY PRESS

AMERICAN BRANCH

PRINTED IN THE UNITED STATES OF AMERICA

PREFACE

The position that Medical Science has now assumed in the social polity

demands that all educated men and women should have some knowledge

of the subject, whether they have had a medical training or no. In

these pages the author seeks to place before the reader, who is

without special knowledge, some account of Medicine as a Science. For

this purpose the historical method is peculiarly suited, since it

recapitulates, in some measure, the actual stages through which each

learner must pass. Though the story told here opens with Greek times,

the narrative of the earlier period is so condensed that more than

half the book is devoted to modern Medicine, which is presented as a

natural outgrowth of an ancient tradition. An attempt has been made to

keep the account as simple and as elementary as possible and to make

the smallest demands on the scientific equipment of the reader. The

slight divergence, in some matters, of the interests of American and of

English readers, has been held in mind, so that, it is hoped, the book

may be useful to both classes.

Throughout the work two particular aims have been steadily kept in

view: first, to stress the principles of Medicine rather than the

details of practice; second, to treat of those principles in as small a

space as may be. For ‘principles’ the author has substituted at times

the word ‘Philosophy.’ He would, however, beseech the timid reader

to take no alarm at a word, for he employs the term ‘Philosophy’ in a

time-honored fashion, and he undertakes not to plunge deep into the

labyrinth of Metaphysic. The Philosophy of Medicine stands here for the

disinterested study of the theory of the subject, without reference to

its application to particular instances.

Certain omissions in the book are justified by the author’s forthcoming

publication of a history of the biological sciences treated along

somewhat similar lines. It has thus, for example, seemed superfluous to

include here any but casual references to such highly important topics

as the study of hereditary characters or the experimental investigation

of developmental defects. It is, however, the duty of the author

to direct attention to certain other omissions necessitated by the

compression of the work into a small compass. The history of Medicine,

as here treated, is essentially a history of ideas. The personal

element has been kept wholly in the background and very little space

has been allotted to biographical matter. Nor do the limits of the book

permit any discussion of the status of medical men, and very little

even of their training. On this account many who in their day were

remarkable rather for the influence they exerted than for the advances

in knowledge which they initiated find no commemoration here. This line

of treatment has involved omission of reference to those teachers to

whom the author himself owes most, Sir William Osler and Sir Clifford

Allbutt.

A work on Medicine must be colored, in some degree, by its author’s

conception of the nature of Life. On this theme there are divers views,

for the full discussion of which there is here no place. The author

professes himself, however, an adherent of a school of thought that is

not, at present, greatly in fashion. He ranges himself as a vitalist

under the banner of Aristotle and as a follower in the goodly company

of Harvey, Hunter and Virchow, of Claude Bernard and Johannes Müller.

He believes that there is a principle in living things that cannot

be expressed in chemical or physical terms. He believes that this

principle works to an intelligible end, that it is an _Entelechy_, an

indwelling purposiveness, and that it is as real a thing as anything

that is.

_They are right who hold ‘soul’ to be not independent of body and yet

not a kind of body. ‘Soul’ is not body but something pertaining to the

body and dwelling therein, and, what is more, specific to each body.

Our forebears erred in seeking to fit the ‘soul’ into a body without

regard to the nature and qualities of the body, for the association

of ‘soul’ and body is by no means thus at random. And so indeed we

might expect, for the ‘Entelechy’ of each being comes naturally to be

developed in the potentiality of each being, that is to say in the

matter proper to it. Whence is manifest that the ‘soul’ is a certain

‘Entelechy’, a notion or form of that which has capacity to be endowed

with ‘soul’._ Aristotle, Περὶ Ψυχῆς, _II_, § 2.

The author is well aware that this conception is neither useful

nor helpful for physiological research in the present state of our

knowledge. That is a very good reason for excluding it, as the vitalist

Claude Bernard excluded it, from the physiological laboratory. But

it is not a good reason for abandoning a point of view which does

something to make existence intelligible. On the contrary, turning from

the physiological laboratory to the living being as a whole, it is just

the indwelling purposiveness that is, before all things, most worthy of

consideration. Every function, every structure, every instinct, habit,

or reflex, every mental activity that is related to health--and which

is not?--may throw some light thereon. It appears to the author that

the scientific method is by far the mightiest weapon that has as yet

come within man’s grasp, for the illumination of these multitudinous

entities. The searching accuracy and power of that superb instrument,

wielded by human reason in the quest of human health, is the theme of

this volume. And yet, notwithstanding its triumphs, the experimental

method, as applied in the separate sciences, has, of its nature,

certain limitations with reference to living beings in general and

living human beings in particular.

It is the business of each of the sciences--it is indeed an essential

part of the method of Science--to separate a circumscribed part of

the Universe for consideration in and for itself. Men of Science must

thus perforce become Chemists, Physicists, Astronomers, Botanists,

Cytologists, Statisticians, and the like. In this respect modern

_Science_ differs most profoundly from medieval _Scientia_ and from

ancient _Philosophia_. ‘Specialization’ follows modern _Science_ as

shadow follows substance. The new method has triumphed wonderfully in

these last centuries and it is mere folly and obscurantism to seek

to place intellectual stumbling-blocks in its path. Nor must we be

afraid of shadows. The author does plead, however, that, while the

Man of Science must, from the very nature of his method, cut off part

of his universe of experience from all other parts, he should bear in

mind, when not employed on his special task, that he has so cut off

and isolated his special experience, of deliberate and set intent. To

bear this fact in mind should not mean and must not mean that Science

fails to influence our view of the world as a whole, but it should

mean and must mean the basing of our view of the world as a whole on

experience as a whole, and not on an artificially separated fragment

of experience. For Man is neither a walking test-tube, nor a living

anatomy, nor a colony of cells, nor a self-repairing machine that

carries its own spare parts, nor a mere summation of the factors of

heredity and environment, nor, for that matter, is he a disembodied

spirit. But he is a being with a purpose. Of that purpose he, of his

nature, can know very little, since it is a part of that through which

he knows. Yet some glimpse of that purpose, though seen through a mist

and ever so dimly, we may perhaps gain from the view-point on which the

stony tracks of the separate sciences do ultimately converge. If the

separate sciences did not so conspire to one end, why should we ever

bother our heads or weary our limbs over their steep ascents? Are there

not rosier paths that we might tread?

Throughout this book, then, the ideal kept in view is the description

of Medicine as a Rational Discipline involving many and perhaps all the

sciences. Medicine is not now and never has been followed wholly in the

scientific spirit. But it is the story of the scientific elements in

Medicine which is here to be told, and other aspects are passed over

with a silence which must not be interpreted as the silence of contempt.

No two men undertaking the task here outlined would make quite the

same selections or allot emphasis in quite the same manner. Doubtless

the author has erred by omission and by commission, through ignorance

and through misconception, but he hopes that he has never erred

through prejudice. The ideas that he recounts are those that present

themselves to him as the most important and fruitful within the range

of scientific Medicine, and he is prepared to revise his opinions both

on matters of fact and on matters of stress. He will therefore be very

grateful for any corrections or suggestions.

The number of names mentioned in the book has been reduced to the

utmost limit that has seemed feasible. In recounting many episodes

one name has often been taken as an example or type, and thus perhaps

sometimes an injustice has been done to other workers, no less

important but perhaps less typical. When modern times and living

persons are reached the selection becomes not only difficult but also

delicate, but the reader must remember that the names are not always

chosen for their eminence but sometimes rather as typifying the various

movements that have to be discussed. There is a further complication in

that an attempt is here made to bring history right up to date. Very

few names of living men are mentioned, though the work of many living

men is discussed. Though the author has sought to refrain from passing

any judgment on such latter-day conclusions the value of which does not

seem to him clearly and firmly established, yet even this course in

itself implies a judgment, and one in which he is even more likely to

err than in other topics of which the book treats. Nevertheless, some

such judgment seems necessary to make the book a coherent whole.

There are several from whom the author has had help in the writing

of this book. Mrs. Singer has criticized every detail, and has

considerably modified its form. No English writer on the History of

Medicine can fail to refer to the great work of Lt.-Col. Fielding H.

Garrison of the United States Army and of the Library of Congress at

Washington. The author of this book owes much to Lt.-Col. Garrison’s

splendid bibliography, but even more to constant correspondence,

carried on now through a good many years, with the man who made it.

He owes a similar debt to a very old-standing friendship with Dr. E.

T. Withington of Oxford, to whom he takes the liberty of dedicating

this book. Professor Graham Wallas, Emeritus Professor of Sociology

in the University of London, and Professor J. C. Drummond, Professor

of Biochemistry in the University of London, have both read the book

in proof, and have made a number of suggestions and corrections.

Help on special points has been given by Dr. Clark-Kennedy of Corpus

Christi College, Cambridge, Dr. Raymond Crawfurd, Registrar of the

Royal College of Physicians of London, Dr. J. W. Eyre, Professor

of Bacteriology in the University of London, the Rev. Father J. R.

Fletcher, who has the unusual distinction of being both a Priest and

a Physician, Dr. K. Franklin of the Pharmacological Laboratory in the

University of Oxford, and Dr. William Robson, Lecturer in Law in the

University of London, as well as by the author’s pupils Dr. Ivor Hart,

Dr. J. F. Prendergast, Dr. Dorothy M. Turner and Mr. F. Prescott, M.Sc.

To all of these the author would tender his grateful thanks.

CHARLES SINGER.

UNIVERSITY COLLEGE, LONDON. _January_, 1928.

CONTENTS

PREFACE vii-xiv

LIST OF ILLUSTRATIONS xix-xxiv

I. ANCIENT GREECE, to about 300 B.C.

§ 1. Origins of Greek Medicine 1

§ 2. The Hippocratic Physician 13

§ 3. Hippocratic Practice 18

§ 4. Aristotle 27

II. THE HEIRS OF GREECE, from about 300 B.C. to about A.D. 200

§ 1. The Alexandrian School 36

§ 2. Medical Teaching in the Roman Empire 41

§ 3. Medical Services of the Roman Empire 45

§ 4. Roman Hospitals 48

§ 5. Galen 50

§ 6. The Final Medical Synthesis of Antiquity 53

III. THE MIDDLE AGES, from about A.D. 200 to about A.D. 1500

§ 1. The Period of Depression in Europe 61

§ 2. Arabic Medicine 66

§ 3. The Medieval Awakening 68

§ 4. The Universities 70

§ 5. Medieval Anatomy, Surgery, and Internal Medicine 72

§ 6. Medieval Hospitals and Hygiene 77

IV. THE REBIRTH OF SCIENCE, from about 1500 to about 1700.

§ 1. The Anatomical Awakening 82

§ 2. The Anatomical Reaction on Surgery 92

§ 3. The Renaissance of Internal Medicine 95

§ 4. The First Physical Synthesis 102

§ 5. The Revival of Physiology 108

§ 6. Microscopic Analysis of the Animal Body 115

§ 7. From Alchemy to Chemistry 122

§ 8. The Medical Theorists 126

V. THE PERIOD OF CONSOLIDATION, from about 1700 to about 1825.

§ 1. The Reign of Law 135

§ 2. The Rise of Clinical Teaching 138

§ 3. Physiology passes to the Modern Stage 142

§ 4. Some Physiological Advances 145

§ 5. Discovery of the Nature of the Air 151

§ 6. Morbid Anatomy becomes a Science 156

§ 7. Clinical Methods and Instruments 159

§ 8. Surgery and Obstetrics 161

§ 9. The Beginnings of the Science of Vital Statistics 166

§ 10. Military, Naval, and Prison Medicine 169

§ 11. The Industrial Revolution 172

§ 12. Control and Recognition of Epidemic Diseases 182

VI. PERIOD OF SCIENTIFIC SUBDIVISION, from about 1825 onwards.

§ 1. Origins and Implications of Scientific Specialization 186

§ 2. The Revolution in Preventive Medicine 192

(_a_) Preventive Medicine in Britain 193

(_b_) Preventive Medicine in U. S. A. 197

§ 3. The Transition to a Physiological Synthesis 203

(_a_) Anatomy and Embryology in the Earlier Nineteenth Century 204

(_b_) Chemical Physiology in the Earlier Nineteenth Century 205

(_c_) Nervous Physiology in the Earlier Nineteenth Century 207

§ 4. The Experimental Foundations of Modern Medicine 211

(_a_) The Work of Johannes Müller 211

(_b_) The Work of Claude Bernard 213

(_c_) The Work of Karl Ludwig 215

§ 5. The Cell Theory and Cellular Pathology 219

§ 6. Establishment of the Doctrine of the Germ Origin of Disease 224

§ 7. Anaesthesia 235

§ 8. The Revolution in Surgery 237

§ 9. Some Modern Surgical Advances 243

§ 10. Bacteriology becomes a Special Science 249

§ 11. Some Important Bacteriological Results 253

§ 12. The Study of Immunity 259

§ 13. Some Practical Applications of Immunity 263

§ 14. The Conquest of the Tropics 271

(_a_) Yellow Fever 273

(_b_) Malaria 280

§ 15. The Changed View of Insanity 286

§ 16. The New Movement in Psychology 293

§ 17. The Revolution in Nursing 295

§ 18. Some Modern Physiological Concepts of Clinical Import 301

(_a_) Ductless Glands and Internal Secretions 302

(_b_) Nervous Integration 308

(_c_) Vitamins 311

§ 19. Knowledge of the Eye and its Disorders 313

§ 20. Investigation of the Nature and Action of Drugs 322

(_a_) Entry of Vegetable Drugs into the Pharmacopoeia 322

(_b_) Active Principles 323

(_c_) The Alkaloids 325

(_d_) The Glucosides 327

(_e_) The Study of Pharmacology 328

(_f_) Chemotherapy 329

§ 21. Interpretation of Collective Medical Data 333

EPILOGUE 351

INDEX 364

LIST OF ILLUSTRATIONS

1. Hippocrates. British Museum, second or third

century B.C. _Frontispiece_

2. Ivory and gold Minoan statuette of a votaress in a

state of ecstasy. By kind permission of the Museum

of Fine Arts, Boston, U.S.A. 5

3. Surgical instruments recovered from Babylonian

sites. Reproduced by kind permission of Professor

Meyer-Steineg of Jena 5

4. Clay model of sheep’s liver used for instruction in

divination in a Babylonian temple school. Drawn

from the object in the British Museum 6

5. Imhotep. From a statuette in the British Museum 8

6. Aesculapius. Photograph Anderson 8

7. Scheme illustrating some of the sources of

Hippocratic Medicine 9

8. A Greek clinic of about 400 B.C. From a vase

painting 17

9. Instruments used by Greek surgeons 20

10. The _Ladder of Nature_ according to Aristotle 28

11. The womb with the names of its parts as given by

Aristotle 29

12. Embryo dogfish, _Mustelus laevis_, after Johannes

Müller 29

13. The four _Elements_ in association with the four

_Humours_ and the four _Qualities_ 34

14. Inscribed tablet of about 100 B.C. from the wall of

the temple of Kom-Ombos in Upper Egypt 40

15. Roman surgical instruments of the first century

A.D. found at Pompeii 44

16. Aqueduct of Nero from an engraving by Piranesi 47

17. Roman advanced dressing-station. From Trajan’s

column 48

18. Island of St. Bartholomew in the Tiber at Rome.

From an engraving by Piranesi 51

19. Dissection of the hand of a man 57

20. Dissection of the hand of a Barbary ape 57

21. Galen’s Physiological System 59

22. The earliest known representation of St. Luke as a

Physician 63

23. Picture of Trephining, from a thirteenth-century

manuscript 63

24. Illustrating the mode of action of the trephining

instrument used by the surgeon in Fig. 23 64

25. Scene at a siege of Salerno, from a manuscript

prepared in South Italy early in the thirteenth

century 65

26. A Jewish translator receiving an Arabic medical

volume from an Eastern potentate (right) and

handing it, translated into Latin, to a Western

monarch (left) 69

27. Medieval Bologna, from a mural painting of about

1500 in the town-hall of the city 73

28. An anatomical lecture at Padua in the fifteenth

century, from a contemporary Italian woodcut 75

29. A ward in a hospital at Paris in the sixteenth

century. Reproduced, by kind permission of M.

Édouard Champion, from D. L. MacKay, _Les hôpitaux

et la Charité à Paris au XIII^e siècle_ 79

30. Drawing of Dissection of the Heart by Leonardo da

Vinci 85

31. Title-page of the work _On the Fabric of the Human

Body_, by Vesalius, published in 1543 87

32. Skeleton from the anatomical work of Vesalius 91

33. Artificial arms and hands, designed and figured by

Ambroise Paré 93

34. The ‘Four Temperaments’, from the Guild Book of the

Barber-Surgeons of York 97

35. Earliest picture showing the use of Tobacco 99

36. Allegorical picture illustrating the venereal

plague 101

37. Sanctorius in his balance 107

38. The principle of Galileo’s thermometer 109

39. The application of the system shown in Fig. 38 by

Sanctorius, who used a curved tube 109

40. The adaptation of the instrument, shown in Fig. 39,

as a clinical thermometer 109

41. Galileo’s ‘pulsimeter’ 109

42. Dissection of a vein in the thigh and leg, from

Fabricius 111

43. The circulation of the blood 113

44. The superficial veins, from William Harvey 114

45. Lungs of a frog, showing the capillary vessels,

from Malpighi 116

46-9. Stages in the formation of the chick, from Malpighi

117

49a. One of Leeuwenhoek’s microscopes. Reproduced, by

the permission of Mrs. George Martin, from _The

Asclepiad_, II 118

50-3. Illustrating the blood corpuscles and circulation

after Leeuwenhoek 119

54. The first representation of Bacteria 120

55-56a. Drawings by Leeuwenhoek of the structure of

muscle 121

57-60. Experiments by Swammerdam 123

61. Boyle’s Air-pump 125

62. Descartes’ conception of the relation of a sensory

impression and a motor impulse 128

63. Diagram of Descartes, to illustrate nervous action

129

64. Diagrams from Borelli, to illustrate movements of

muscles 130

65. Diagram of muscular action 131

66. Two Plates from Bernard Siegfried Albinus’

_Anatomical Plates of the Muscles of Man_, Leyden, 1747 141

67. Windmill ventilator designed by the Rev. Stephen

Hales. From a print in the British Museum 147

68-70. Experiments illustrating the effects of metallic

contacts on the nerves and muscles of frogs’ legs.

From A. Galvani, _On Electric Forces_, 1792 149

71-3. Volta’s figures of the electric pile and crown of

cups 150

74-5. Illustrating the chemistry of burning and

breathing, from a work issued by Mayow in 1674 152

76. Apparatus from Joseph Priestley’s _Experiments and

Observations on different Kinds of Air_, 1774 154

77. Lavoisier in his laboratory making experiments on

breathing. From a contemporary sketch 155

78. Part of the lung of Dr. Samuel Johnson, from a

drawing published by Matthew Baillie 158

79-82. Laënnec’s wooden stethoscope, from the first

edition of his work _On Instrumental Auscultation_

161

83. Lying-in scene in the sixteenth century, from a

contemporary work on Midwifery 163

84-6. Early obstetric instruments 164

87. John Hunter’s country house at Earl’s Court,

Kensington, before its demolition in 1886.

Reproduced, by the kind permission of Mrs. George

Martin, from _The Asclepiad_, VIII 165

88. An eighteenth-century Quarantine station (Naples)

173

89-90. Illustrating the textile trade from home industry

to factory work with the consequent break-up of the

family as the labour unit. The upper picture from a

drawing by George Walker, the lower from _Economic

Botany: The Cotton Manufacture_ 175

91. Graph showing approximate growth of population in

England and Wales 1670-1830 176

91a. Tables illustrating vital conditions in the

eighteenth century 177

92. St. Bartholomew’s Hospital at Smithfield, London,

in 1720. From Strype’s edition of Stow’s _Survey_

179

93. The Pest House in Tothill Fields, London, in 1796.

From a print in the British Museum 181

94. Hand of Dairymaid infected with cow-pox, from

figure by Jenner 184

95. A cartoon by Robert Cruikshank 191

96. Annual death-rate in London per thousand living

over 85 years 196

97. The Old _Dreadnought_ Hospital Ship 199

98. Diagram of Transverse section of the Spinal Cord,

&c. 208

99. Diagram to illustrate Reflex 209

100. Diagram to illustrate Cerebral localization 210

101. Thomas Young’s Kymograph 217

102-5. Drawings by Theodor Schwann to illustrate cells

221

106. Organisms of Fermentation, from Pasteur 226

107. Pasteur’s experiment to prove that fermentation is

the result of air-borne organisms 228

108. Bacilli of Anthrax 231

108a. Screw used in the eighteenth and the early

nineteenth century to secure analgesia. Reproduced,

by the kind permission of Mrs. George Martin, from

_The Asclepiad_, VII 236

109. The ‘Donkey Engine’ designed by Lord Lister. Now in

the Royal College of Surgeons of England 241

109a. Operating table used by Lord Lister in the Glasgow

Royal Infirmary. Reproduced, by kind permission of

Messrs. Jackson, Wylie & Co., from _Lister and the

Lister Ward in the Royal Infirmary of Glasgow_ 242

110. ‘Spencer Wells Forceps’ 244

111. Spencer Wells performing an abdominal operation

245

112. An operation in the sixteenth century 246

113. An abdominal operation under modern conditions.

Reproduced, by kind permission of W. B. Saunders’

Company, Philadelphia, from _The Operating Room,

St. Mary’s Hospital, Rochester, Minnesota_ 247

114. Bacilli of Diphtheria 254

115. Bacilli of Plague 255

116. Diagram showing the Incidence of Malta fever 256

117. Bacilli of Tetanus 257

118. Bacilli of Typhoid Fever 258

119. Death-rate of cases of Laryngeal Diphtheria 263

120-1. A common Malaria-carrying mosquito and a Yellow

Fever-carrying mosquito. Reproduced, by kind

permission of the British Museum (Natural History),

from Edwards, _Mosquitoes and their Relation to

Disease_ 272

122. Distribution of Malaria in England and Wales 281

123. The Life-History of the Parasite of Malaria.

Reproduced, by kind permission of Messrs.

Baillière, Tindall & Cox, from C. M. Wenyon’s

_Protozoology_, vol. II 285

124-5. A Malaria-carrying mosquito and a common gnat.

Reproduced, by kind permission of the British

Museum (Natural History), from Edwards, _Mosquitoes

and their Relation to Disease_ 287

126. Chart of cases of Malaria reported in Italy in

recent years 287

127. ‘The Retreat’ near York. Reproduced, by permission

of Messrs. Kegan Paul, Trench, Trubner & Co., from

Tuke, _Chapters in the History of the Insane in the

British Isles_, 1882 289

128. Florence Nightingale at Scutari. Photograph,

Rischgitz Collection 299

129-30. Cretinous infant before and after thyroid

treatment. Reproduced by kind permission of the

Royal College of Surgeons 305

131. Diagram to show the structure of the eye 314

132. Diagram to show the nature of accommodation of the

eye 317

133. The Organisms of Syphilis in a smear from the Local

Infection 331

134. Diagram illustrating alteration in Age-distribution

of the population of England and Wales. Reproduced,

by kind permission of the authors, from

Carr-Saunders & Caradog Jones, _Social Structure of

England and Wales_ (Clarendon Press) 335

135. Death-rate from Cancer of the Tongue. Reproduced,

by kind permission of the Editors, from _The

Quarterly journal of Medicine_, vol. v, No. 5 337

136. Death-rate from Cancer of the Lip. Reproduced, by

kind permission of the Editors, from _The Quarterly

Journal of Medicine_, vol. v, No. 5 338

137. Death-rate from Cerebral Haemorrhage. Reproduced,

by kind permission of the Editors, from _The

Quarterly Journal of Medicine_, vol. v, No. 5 340

138. Curve showing percentage of deaths from Phthisis to

total deaths 343

139. The normal curve of error 345

140. Curve of monthly number of deaths from Small-pox

during an epidemic at Warrington, Lancashire, in 1743 346

141. Curve of weekly number of cases of Scarlet Fever

during an epidemic at Glasgow in 1892 346

142. Analysis of curve representing death-rates from

Summer Diarrhoea in London over a long period of

years 347

I

ANCIENT GREECE

(TO ABOUT 300 B.C.)

§ 1. _Origins of Greek Medicine._

Scientific Medicine began with the Greeks. The Greeks not only started

scientific Medicine upon its course, but also provided the substantial

basic elements of our anatomy, physiology and pathology, and above

all, perhaps, our conception of the bodily ‘constitution’, ‘habit’ or

‘temperament’. It is from the Greeks that we derive almost all our

medical nomenclature. When to this we add that our medical traditions

are inherited through a direct and continuous chain from the Greek

practitioners, it becomes evident that the debt that Medicine owes to

this marvellous people is great indeed.

Now this debt has become associated with two or three great figures.

The names Hippocrates, Aristotle, Galen, are familiar to all. Yet it is

not always recognized that these men were but the representatives of a

widely extended and long-lasting system. Greek Medicine was, in fact,

like modern Medicine, the result of centuries of carefully recorded,

collated and progressive research. Greek Medicine first assumed a

scientific aspect with the Ionian and Italo-Greek philosophers at the

very beginning of the sixth century B.C. It continued to make important

advances until the death of Galen at the very end of the second century

of the Christian era. Thus the life-span of progressive and scientific

Medicine among the Greeks was no less than eight hundred years. With

the most tolerant use of the words ‘scientific’ and ‘progressive’,

we can hardly place the beginnings of modern Medicine in Europe

before the end of the fifteenth century. Thus our own system has only

been developing its characteristic features for some four and a half

centuries, which is but little more than half the course that Greek

science ran.

It is evident, therefore, that we may have much to learn from the

Greeks, not indeed in matters of actual fact or observation--for nearly

all that is _directly_ useful in their writings has been absorbed long

ago into our medical literature--but in spirit and method. From a

study of the character and course of Greek medical science we can gain

hints of the snares and pitfalls and catastrophes into which the Art

of Medicine may at times be led. Further, by study of the practice of

Medicine under conditions so different from ours, we learn something

of what is truly permanent in the Art of Healing. Lastly, by tracing

the growth of the Science of Medicine, as it arose among the Greeks and

as it died in the hands of their less worthy descendants, we may take

alike example and warning. We may learn to distinguish the healthy and

vigorous growth of a science from the stunted and deformed products

that are often acclaimed, even in our own times, as Wisdom’s final word

to Man.

It has been said that, ‘save the blind forces of Nature, nothing lives

or moves which is not Greek in origin’. The saying needs modification,

for there is a thing which still lives and moves that is not Greek in

origin, a blind force which is not a blind force of Nature. It is the

force of Superstition, of that age-old belief that Nature will give

us something for nothing, which is expressed by the word ‘Magic’.

The Greeks were no more free from that contemptible fallacy than

are the men of our own days. But the greatest of the Greeks stood

wholly above such folly, and we can watch the Greek mind gradually

lifting itself from that primeval mental attitude which is older than

any known culture, older perhaps than any known race, the attitude

of Nature-Worship, or ‘Animism’. To give an idea of how the ‘sweet

reasonableness’ of the Greek mind gradually dissipated the animistic

fog, a few words must be said about the history of the Greeks. Without

that amount of history it would seem a miracle that Man ever became

reasonable at all.

The Medicine we call Greek might be described as the system which

prevailed in ancient times in that half of the Mediterranean area which

lies east and south of the Italian Peninsula.

Up to about 1000 B.C. most of the coast-lands of this Mediterranean

area were inhabited by that very remarkable people, the Minoans.

These have left some extraordinary remains, the full significance

of which has not yet been revealed. The general development of the

Minoan civilization has, however, been clearly outlined by modern

archaeological investigation. This has resulted in an entirely new

interpretation of the story which Homer tells in the _Iliad_. The siege

of Troy represents an attack by the invading Greeks on one of the last

Minoan strongholds. About 1000 B.C. the whole Eastern Mediterranean

basin was being overrun by the Greek tribes coming in from the north.

These Greeks were no pure race, but a mixed multitude of invaders

who came along several lines of advance. As always happens in such

invasions, the conquered were not exterminated, but mingled with the

invaders. Thus the Greeks, as they advanced, absorbed much of the

culture and outlook of the civilization that they submerged.

In considering the history of Rational Medicine we are concerned

chiefly with two main invading streams of Greek tribes: that of the

Dorians, who passed towards Crete and towards the Island of Cos and the

opposite peninsula of Cnidus, and that of the Ionians, who colonized

most of the remaining part of western Asia Minor. These two peoples

were, between them, responsible for the main intellectual output of the

Greeks of those early days. The medical system which they initiated

first took shape in western Asia Minor, and thence became diffused over

the whole of the Greek world. The Greek system of Medicine which thus

arose in Asia Minor had various roots, as indeed the Medicine of a

mixed people, living under very complex social conditions, was bound to

have.

Firstly, there was the submerged civilization of the conquered Minoan

folk. It is probable that the cult of the serpent--so constantly

associated with Aesculapius and still used as a medical emblem--was of

Minoan origin, for the serpent was a symbol much used in the Minoan

religion (Fig. 2). It is probable too that some of the hygienic ideas

of the Greeks were derived from the same source, for the Minoans had an

excellent system of drainage. We can, however, say little on this head

because the interpretation of the Minoan records is still hidden from

us.

[Illustration:

FIG. 2. IVORY AND GOLD MINOAN STATUETTE of a votaress in a state

of ecstasy. In either hand she holds a serpent, illustrating the

importance attached to this animal in the Minoan cult. From the Museum

of Fine Arts, Boston, U.S.A.

FIG. 3. SURGICAL INSTRUMENTS recovered from Babylonian sites. There are

here represented three knives, a saw and a trephine. These instruments,

which illustrate the state of surgery in the ancient Mesopotamian

civilization, are in the possession of Professor Meyer-Steineg of Jena,

by whose permission they are here reproduced.

]

Secondly, we have to remember that the shores of Asia Minor lie on the

outskirts of the great civilization which had grown up in the valley

of the Tigris and the Euphrates. The Greeks drew from that source much

of their more superstitious beliefs, as well as some, at least, of

their scientific method. On the one hand, the demoniac theories that

bulk so largely in later Greek medicine doubtless came from Assyria

and Babylonia. The Medicine of the New Testament, for instance, with

its casting out of devils, is of Mesopotamian origin. But, on the

other hand, the Mesopotamian peoples had for long ages laid up a great

treasury of observation, notably of astronomical data which were

often applied to astrological ends. There was also some knowledge of

anatomy derived from the entrails of animals used in divination (Fig.

4). Working on the basis of these records, the Greeks were able to

erect a scientific method which appears as a prominent feature in

their intellectual life in later centuries. Moreover, there was in

Mesopotamia a standardization of both medical and surgical procedure

which the nimble-witted Greeks were quick to adopt (Fig. 3). On its

lower and less intelligent side, however, the Mesopotamian material was

made to minister to Greek superstition and especially to astrological

belief.

[Illustration:

FIG. 4. CLAY MODEL OF SHEEP’S LIVER used for instruction in divination

in a Babylonian temple school. The object is now in the British Museum.

It is covered with cuneiform writing, the nature and contents of which

fix its date as about 2000 B.C. The writing is here omitted for the

sake of simplicity.

Various parts of the liver have their Babylonian technical terms and

can be identified with parts recognized by modern anatomists. Some of

these modern terms are written on our drawing.

To each hole in the original model an inscription containing a forecast

is assigned. The diviner made his forecast by comparing an actual

liver with this clay model at each point corresponding to a hole. His

forecast was elaborated according to the state of the liver at all

these points.

]

Thirdly, to the Egyptian civilization the Greek debt was also

considerable. Many drugs were derived from Egypt and others were

suggested by Egyptian practice. The basis of Greek medical ethics,

too, can be traced to Egypt. Some of the practical devices of Greek

Medicine, such as the forms of the surgical instruments, were of

Egyptian origin. Nor can we neglect the statement made by the Greeks

themselves, that mathematical knowledge--the test and index of all

scientific growth--came to them first from Egypt. Lastly, we note that

the Egyptians deified a physician, Imhotep (Fig. 5), in exactly the

way that the Greeks deified their physician Aesculapius (Fig. 6). Both

Imhotep and Aesculapius were, in fact, historic personages, and their

evolution into gods presents many interesting parallels.

[Illustration:

FIG. 5. IMHOTEP, originally a physician, subsequently deified as an

Egyptian god of Medicine. From a statuette in the British Museum.

FIG. 6. AESCULAPIUS, originally a physician, subsequently deified as a

Greek god of Medicine. He holds a staff, around which a serpent twines.

From a statue in the Capitoline Museum at Rome.

]

The Greeks of western Asia Minor, thus drawing material from many

sources, came to develop, towards the end of the seventh century B.C.,

a philosophical system from which the whole of their Science may be

said to be a natural growth. Factors in this development were the

medical schools of Cos, where Hippocrates was born, and of the opposite

peninsula, Cnidus. These schools were in active operation by the sixth

century B.C. By the middle of the fifth century they were important

elements in the growing complexity of Greek life. Much of the so-called

_Hippocratic Collection_, which contains the earliest Greek medical

writings that have survived, must have been put together somewhere in

the fourth century B.C., though its final recension is certainly later

(Fig. 7). In that final recension Persian and Indian elements were also

included, though to what degree is still very uncertain.

[Illustration: FIG. 7. SCHEME ILLUSTRATING SOME OF THE SOURCES OF

HIPPOCRATIC MEDICINE]

But the picture of the development of Greek Medicine is not yet

complete. Although we inherit the scientific spirit from the Greeks,

and although they set a standard for all time of the purest and

most disinterested type of medical practice, they are also in part

responsible for some of the basest forms of medical jugglery that have

afflicted and still afflict mankind. The medicine of the physicians was

only one of their medical systems. There was a far lower form which

gradually passed into the hands of the priests. The temple jugglery of

Greece is ancestor, both by imitation and by direct tradition, of much

medieval and modern medical miracle-mongering.

Furthermore, in ancient as in modern times, all medical men were not

equally pure in aim or scientific in method. The practice of some Greek

physicians was more than flavored with magic. In justice, also, it

must be said that not all priests were mere charlatans, and that there

are traces of scientific method in the treatment of patients in the

temples. There was, indeed, a relation between the practice of some

of the physicians among the Greeks and that of some of their priestly

magicians. We shall not attempt to determine the actual extent and

nature of this relationship. For our purpose it is enough that the two

systems were quite distinct in their most typical developments.

The temple system of Greek Medicine was associated from an early date

with a deity, Asklepios, or, to give him his better-known Latin name,

Aesculapius. Numerous representations of him have come down to us, and

in them we see him gradually molded to a particular type. He becomes at

last an aged man of noble, benevolent and dreamy aspect, holding in

his hand a staff around which a serpent twines (Fig. 6). The cult of

the god Aesculapius was carried on at numerous sites. The best known,

both from literature and excavation, is Epidaurus. The conditions there

are typical of those in other Aesculapian centers.

Epidaurus is about thirty miles from Athens. It lies between two

considerable ranges of hills, and the country bears still, in its

customs and place-names, some remnants of the ancient cult. One

tradition tells that a certain maiden, Koronis, being with child by

Apollo, brought forth the infant Aesculapius on the mountain above

Epidaurus. There is still a village named Koroni hard by. She fled

to conceal her shame and left the child on the mountain, where it

was tended by a goat and watched over by a dog. The infant performed

various miracles which we need not pursue, though the temple arose on

the site where he is said to have wrought them. One of his miracles,

however, has a wider interest and is worth recounting. A certain

Hippolytus, falsely accused of impure relations with his stepmother,

was slain by the gods in answer to the curses of his father, Theseus.

Raised from the dead by the wonder-working Aesculapius, he reappears in

legend at the Arician grove in Italy. ‘There’, says a Greek chronicler

of the second century A.D., ‘he became a king and devoted a precinct

to Artemis, where, down to my time, the prize for the victor in single

combat was the priesthood of the goddess. The contest was open to no

freeman, but only to runaway slaves.’

The son slain by his father and then rising from the dead; the runaway

slave seeking sanctuary with Artemis in her grove, allowed his liberty

and elevated to the priesthood there; the priesthood held only so long

as the priest can guard it in mortal combat against the next runaway

slave; this succession of slave kings and priestly murders has touched

the imagination of the poets and artists in ancient and in modern

times. The sacred grove of Artemis stood by the side of the lake of

Nemi:

The still glassy lake that sleeps

Beneath Aricia’s trees--

Those trees in whose dim shadow

The ghastly priest doth reign,

The priest who slew the slayer

And shall himself be slain.

It is a picture utterly out of accord with the general trend of

classical mythology. Long ago scholars saw therein a remnant of a

submerged faith, that ancient ‘Nature worship’ which survived among the

Greeks, and survives with us. From this incident is named the great

classical work of Anthropology, _The Golden Bough_. By this story and

by all that it implies, by all that learning has drawn out of it and

associated with it, the history of Medicine comes into contact with the

brooding spirit of savage man. Into that dark realm we shall not enter

in this volume.

History is the tale of the spirit of Man unfolding itself. This process

is always slow, often imperceptible, sometimes retrograde, yet over

long periods of time it is sure. Where no evolution of the spirit can

be traced true history cannot be written, wherefore no man can write a

history of human folly. Irrational man, driven by disease and fear of

death, exhibits the same follies in all ages. The medical follies and

superstitions of our own days are as in those when Aesculapius claimed

men’s allegiance. His garments and his names are changed, his temples

are transformed, his priests assume other titles, but his face is the

same, and he works the same wonders with about the same frequency. It

is of Rational Medicine that we have henceforth to speak.

§ 2. _The Hippocratic Physician._

We turn to the other side of the picture. Nothing could be in greater

contrast to the orgies of the savage, the dark ways of the magician,

or the charlatanry of the priests, than the serene spirit of wisdom

which pervades the best Greek Medicine. The finest presentation of that

system is to be found in a group of about a hundred works that have

been associated together since antiquity under the name of Hippocrates.

It is known as the _Hippocratic Collection_.

It will naturally be asked, ‘Which of these works is by the man whose

name they bear?’ To that question, alas, no definite answer can be

given. There is no single work which we can state with certainty to

be the composition of the Father of Medicine. The books of which the

_Collection_ is composed are the work of a number of authors, belonging

to different schools, holding various and often contradictory views,

living in widely separated parts of the Greek world and writing at

dates divided from each other, in the most extreme cases, by perhaps

five or six centuries. Of the finest books of this collection we can

but say that they contain nothing inconsistent with a Hippocratic

origin, that their ethical standpoint is in accord with the Hippocratic

ideal, and that they are the work of physicians of great intellectual

power and experience.

If we ask what is known about Hippocrates himself, and if we seek

information rather than entertainment, our answer will be almost as

meager. Hippocrates is no mythical figure, for he is mentioned with

high respect by his younger contemporary, Plato. He was the son of a

physician, and was born at Cos about 460 B.C. The most active period

of his life thus began about 420 B.C. His death is placed between 377

and 359--the latter would make him 101, an appropriate age for a great

physician. He led a wandering life, and is heard of at Cos, Thasos,

Athens, in Thrace and elsewhere, and lastly in Thessaly, where his

grave was long shown. Among his pupils were his two sons, and his

son-in-law. Of the work of the latter we have a fragment preserved both

by Aristotle and in the _Hippocratic Collection_ itself.

That is all that is known about the Father of Medicine. We have not

even his portrait. Yet we have something far better; we have an

idealized representation of what the Greek would wish his physician

to be. It is a noble bust to which the name of Hippocrates was early

attached. Many copies exist (see Frontispiece). The calm, righteous

and dignified presence which it portrays has stamped itself on the

consciousness and conscience of those who follow the Art of Healing. To

that gracious figure the medical man will continue to pay homage.

If critical examination has dealt thus hardly with the Hippocratic

writings and with Hippocrates himself, what has been left which we

may surely derive from the Greek medical system? The answer is that

Medicine has from the Greeks two great things: the picture of a man and

the institution of a method.

The man is Hippocrates himself. His figure, gaining in dignity what it

loses in clearness, stands for all time as that of the ideal physician,

for the ideal is there and is clearly set forth in these great

writings, whether we discern the details of his earthly features or no.

Calm and effective, humane and observant, prompt and cautious, at once

learned and willing to learn, eager alike to get and give knowledge,

unmoved save by the fear lest his knowledge may fail to benefit

others--both the sick and their servants the physicians,--incorruptible

and pure in mind and body, the figure of the greatest of physicians has

gained, not lost, by time. In all ages he has been held by medical men

in a reverence comparable only to that which has been felt towards the

founders of the great religions by their followers. The figure of the

Hippocratic physician has been of incalculable spiritual value to the

medical profession in the twenty-three centuries that have passed since

his death.

So much for the man. We turn now to the method.

The _method_ of Hippocratic medicine is that known to-day as the

_experimental_ or better _experiential_. It was employed among the

Greeks for centuries after the death of Hippocrates. Then came a

time when a social and philosophical upheaval prevented its further

prosecution. For the thousand years that followed the break-up of the

Roman Empire the medical practice of Europe was at best a corrupted

imitation and misunderstanding of the Hippocratic teaching; at worst

it descended to a low level of Animism and Magic. Then there was a

rally. Slowly--very slowly at first--the foundations of Modern Science

were laboriously laid. Among the first elements in this scientific

Renaissance was the recovery of the Hippocratic works.

A short history of medicine · 第 1 / 23 段