Of the bad effects of mercury on the constitution much might be said.

Treatises have been written on mercurial pox, a species reported to

be much the most violent; and others have detailed an accumulation

of evils, under the title of mercurial disease. There is no doubt

that extensive, deep, and sloughy ulcers of the throat are produced

by mercury; and of this I witnessed the following unexceptionable

instance:—The fauces presented one extensive mass of ulceration,

sloughing at its margins, and the uvula was almost detached. The

patient was an old and emaciated woman, who neither had, nor could

be supposed to have, any venereal complaints. She employed herself in

coating mirrors with quicksilver, and to that she ascribed her malady.

In fact, her system had been long under the influence of mercury, in

consequence of her occupation. When I visited her, her daughter and

husband, the latter of whom was paralytic, and almost bedridden, were

affected, from the same cause, with a pustular eruption of the face,

with disease of the nostrils, and snivelling. Another old woman had

numerous and deep ulcers of the fauces, tongue, and lips, having been

kept unmercifully under mercury for nine continuous months. She had,

besides, taken it from time to time, for upwards of four years, though

her sole complaint was slight sore throat. Pains of the joints, too, I

believe, are attributable to the use of mercury. That medicine has no

power to prevent the occurrence of nodes, for these often form during

its action. Affections of the periosteum are very frequent in horses

and other lower animals, and also easily excited in some human subjects

who have neither had pox nor been put under mercury; but in no instance

of venereal disease have I observed serious affections of the bones

where mercury had not been given. Even the advocates for mercurialising

speak of mercurial nodes. It has been asserted that nodes do not occur

when mercury has been given for liver or other complaints; but they do

form under such circumstances, though not so frequently as when the

medicine has been exhibited during venereal symptoms. A cachectic state

is often induced by a continued use of mercurial preparations, or at

least by mercury and disease together, in constitutions not originally

strong. It is marked by pale lips; bloodless conjunctiva; a rough

anserine skin; a relaxed state of the mucous membranes; hemorrhages

from these, particularly from the gums, which may prove fatal, as

I have myself witnessed; exfoliations of the alveolar processes;

slimy stools; pale urine; pains of the limbs; sores, showing great

indolence, or even assuming malignant action; dropsical symptoms, and

other evils, of which a lengthened catalogue might be made out. Such

symptoms were often met with when mercury was exhibited for every

trifling or suspected sign of disease arising from carnal conjunction.

On this subject, Mr. Samuel Cooper has well remarked: “Experience has

fully convinced me, that in no forms of chancre, nor in any other

stages of the venereal disease, is it proper to exhibit mercury in

the unmerciful quantity, and for the prodigious length of time, which

custom, ignorance, and prejudice, used to sanction in former days.

Violent salivations ought, at all events, to be for ever exploded. When

I was an apprentice at St. Bartholomew’s Hospital, most of the venereal

patients in that establishment were seen with their ulcerated tongues

hanging out of their mouths, their faces prodigiously swelled, and

their saliva flowing out in streams. The wards were not sufficiently

ventilated, and the stench was so great, that the places well deserved

the appellation of _foul_. Yet, notwithstanding mercury was thus

_pushed_ (as the favourite expression was), it was then common to see

many patients suffer the most dreadful mutilations, in consequence

of sloughing ulcers of the penis; other patients, whose noses and

palates were gone; others who were covered with nodes and dreadful

phagedenic sores.” This woful picture is not exaggerated, and cannot

be too strongly impressed on the minds of young practitioners. A small

quantity of mercury will affect violently some constitutions; as of

those who have been in warm climates, or who have taken much of the

drug, even in this country.

_Eczema Rubrum_, a disease resulting from external causes, but which

may also be produced by mercury, often arises from but a very small

quantity of that medicine even applied externally. It most frequently

affects the scrotum and upper and inner parts of the thighs. It is

preceded by heat and itching in the part; a diffused redness appears,

and the affected surface is rendered rough by the eruption of numerous

minute vesicles. In a short time, these vesicles, if not ruptured,

attain the size of a pin’s head, and the included serum becomes opaque

and milky. The affection soon extends over the rest of the body in

successive large patches, and is accompanied with considerable swelling

of the integuments, tenderness of the skin, and itching. The vesicles

burst, and discharge a thin acrid fluid, which renders the surrounding

surface painful, inflamed, and excoriated. The discharge becomes

thicker, adhesive, and fetid, and by its drying, partial yellowish

incrustations are formed. The disease terminates in desquamation, and

in some cases, the hair and nails are also lost. It is preceded and

accompanied with smart fever, and general disorder of the system.

_Erethismus_ is another occasional consequence of mercury,

characterised by remarkable depression of strength; small, quick, and

often unequal pulse; anxiety, sighing, and trembling; a pale contracted

countenance, and occasional vomiting. While in this state, sudden

exertions are apt to prove fatal.

OF SCALDS AND BURNS.

Different degrees of injury are inflicted on the surface from the

application of heated solids or fluids. The term scald is generally

confined to the effects of heated fluids, whilst burn denotes the

consequences of the application of a heated solid, or of ignited

combustible matter; the latter class of accidents is, in general, the

more serious, yet the former, though not injuring the skin deeply,

gives rise to the most alarming symptoms when a large extent of surface

is affected. A slight degree of heat is productive only of redness of

the surface, with a sharp hot pain, and these symptoms may subside with

or without vesication. However, effusion of serum under the cuticle

often takes place almost immediately after the contact of the heated

body—the cuticle may be destroyed by the intensity of the injury—or the

true skin may die, either partially or throughout its whole thickness,

and the subjacent parts be at the same time injured to a greater or

less depth. But parts, not severely injured at first, may afterwards

perish, violent inflammatory action being excited, which terminates in

sloughing. The neighbouring parts have their vitality much diminished,

by the direct influence of the injury; and hence, when these parts

come to be the seat of increased action, sloughing almost inevitably

ensues, from the want of corresponding power. From the same cause,

subsequent sores are tedious in healing, being so far debilitated as

to be unable to assume full vigour; even slight ulcerations following

vesication contract very slowly; the granulations are flabby, and the

discharge profuse and thin. The inflammation is often at first very

violent, and kept within bounds with difficulty. Burns of the trunk,

particularly of the genital organs, are to be considered as attended

with much danger. And extensive burns and scalds, wherever situated,

are always to be dreaded. Violent constitutional irritation takes

place, dyspnœa is apt to occur, with effusion into the chest of serum,

or a sero-purulent fluid; and the nervous system ultimately becomes

oppressed. Great sinking of the vital powers is generally the immediate

consequence of extensive and severe burns; there is shivering, weakness

of the pulse, cold extremities, anxiety, and vomiting, requiring the

exhibition of warm drinks, and even sometimes of cordials, opium, or

strong stimulants. These must, however, be given with a sparing hand,

or the depression following the excitement is with difficulty got over.

Nor can it be matter of surprise that such serious effects occur, when

we reflect on the extreme sensibility, and highly organised state of

the affected part, and the important functions which it is intended

to perform, as well as those sympathies which it holds with internal

parts, on which life principally depends.

In trifling burns cold applications are generally used—as immersing the

part in cold or iced water. A great variety of remedies are employed,

spiritous, watery, acid, alkaline, cold or hot; some apply a coat of

cotton or flour, some of tar or pitch, and they state that when these

artificial crusts separate, the skin is found healed beneath; in fact,

every practitioner, and almost every individual, possesses a favourite

application for this very common accident. Some have recommended

holding the part to the fire, or plunging it into hot liquid; but this

practice, and all similar, are too severe ever to become general,

when milder means prove equally effectual. Perhaps the most common

applications are, a mixture of lime-water and olive oil, or the ceratum

acetatis plumbi. The vesicles, when left to themselves, burst, expose

an irritable surface, and the acrid discharge from them excoriates

the surrounding skin. Their contents ought to be evacuated by a small

puncture, and the cuticle being left carefully undisturbed, a scab

soon forms, by which the part is protected while healing. In extensive

injuries of the skin, where the cuticle has been altogether destroyed,

finely carded cotton is sometimes applied; it is of use in somewhat

the same way as the cuticle in the former instance, and being a sort

of cushion over the part, prevents it from being irritated by bed or

body clothes, or by the patient’s resting on it. It soon becomes soaked

with the discharge, and must either be frequently changed, or become a

receptacle for pus to putrefy in, and maggots to breed; on account of

these circumstances it is objectionable. Dusting the part with common

flour, starch, or hair powder, is equally advantageous, and much more

convenient; relief is afforded by its immediate application; the parts

are cooled; the flour, absorbing the discharge, is soon formed into

crusts, which effectually protect the surface; and the after-secretion

readily escapes from beneath this, no more moisture being imbibed than

is merely sufficient for the encrustation. The artificial covering

ought not to be removed until completely detached, by purulent matter

accumulating beneath it; then its presence can be of no service, and

its removal is accomplished by fomentation or poultice, and without

pain to the patient; whereas, by pulling off the crusts shortly after

their formation, as some do, whilst they are adherent to the surface,

and protecting it from injury, much pain is given to the patient, the

raw surface is irritated, and made liable to over-action; a useful

application is taken away to make room for another, and, perhaps, not

so congenial. After the spontaneous separation, fresh flour may be

again sprinkled over the suppurating surface, and, if the affected part

is small, it may heal under this application. But when, in burns of

considerable extent, suppuration is fully established, and granulations

have begun to arise, tepid-water dressing, and lotions, are to be

applied as to any other granulating sore; for the reasons already

assigned, the applications require to be of a gently stimulating nature.

In severe cases, there is first extreme depression of the powers

of life, under which patients sometimes sink; but most frequently

this state is obviated by the employment of cordials or stimulants.

But these ought to be administered with caution, for reaction soon

commences, and often increases to well-marked inflammation, requiring

for counteraction low diet, and even bleeding. In such cases gentle

laxatives are preferable to purgatives, as by the latter the patient

is obliged to make frequent movements, and those are always painful.

Stimulants have been strongly recommended, at first powerful, and

afterwards gradually weaker, so as, it was said, to restore the balance

between the affected parts and the system; and the latter is again

to be excited, in order to meet the increased action which the parts

assume. The practice is founded on fancy, and cannot become general,

being in its first part cruel, and in its second absurd. Whilst

debility exists, stimulate cautiously; when over-action ensues, adopt

those measures which are best calculated to subdue excitement; this is

common sense, and the common practice.

During the process of healing, position of the parts ought to be

carefully attended to; contraction of the cicatrices, and cohesion of

opposed surfaces often causing unseemly deformities. Surfaces opposed

to each other, and naturally separate, may be prevented from uniting

by dressing interposed; and contraction of joints is to be guarded

against by keeping the limb extended by splints and bandages. Where

deformity has occurred, the hardened cicatrix which is in fault may

be either divided or excised, and by paying attention to position in

the after-treatment, the evil may be greatly lessened. In the case of

contracted joints, it is not necessary to excise the whole or greater

part of the callous web; simple division is sufficient, if carried deep

enough, through the altered and condensed cutaneous tissue. A horrid

case of deformity is sketched on the next page, and from a very horrid

and atrocious scoundrel, the companion and assistant of Messrs. Burke,

Hare, and Co., the Thugs of the Modern Athens. In such a deformity

the art of surgery could not avail. In others, however, the cicatrix

is not so extensive; it is separated into bands, by the division of

which the position of the head and lip is improved, and the comfort

of the patient much enhanced. In one case, in which I operated with

success very lately, the scar, though extensive, was remarkably soft

and pliable, as much so as the finest kid leather.

[Illustration]

PART SECOND.

OF PARTICULAR SURGICAL SUBJECTS.

INJURIES OF THE HEAD.

_Wounds of the Scalp_ are attended and followed by more dangerous

symptoms than wounds of the integuments on any other part of the

body. This is in a great measure attributable to the nature and

connections of the parts. The subcutaneous fatty matter is condensed,

and closely attached to a firm and unyielding tendinous expansion; and

betwixt these tissues and the pericranium, a loose cellular tissue

is interposed, so as to allow of free motion of the parts. They are

highly vascular, with the exception of the occipito-frontalis fascia,

and between them and the internal parts, as is well known, a free

communication exists. Injuries of these coverings, though at first

apparently trifling, and consequently looked upon as of no importance,

and unattended with danger, often assume a very alarming character.

No injury of the head, in fact, is too slight to be despised, or too

severe to be despaired of.

Punctured and lacerated wounds, more especially those penetrating

all the layers of covering, are frequently followed by violent and

extensive inflammation of all the tissues, with severe constitutional

disturbance, and with delirium and other symptoms denoting functional

derangement of the brain. The swelling is often extensive, involving

the whole scalp, together with the integuments of the face, and

completely shutting the eyelids. In some cases resolution may

be accomplished, but the most frequent termination is extensive

infiltration of purulent matter into the cellular, or even into the

more deep structures, with sloughing of the tendinous expansion.

Collections of matter frequently form in the loose cellular tissue of

the eyelids, when the parts are affected with inflammation, whether

superficial or deeply seated.

As to treatment, after the infliction of an injury, the scalp ought to

be shaved, and the wound cleansed of coagula and foreign substances.

If a large flap of integument is detached, it should be replaced,

and retained as nearly as possible in its natural situation; and

if, for this latter purpose, slips of uninitiating adhesive plaster

and methodical compression prove insufficient, it will be necessary

to employ a very few points of interrupted suture: these, however,

must be removed at an early period, that is, when either adhesion or

suppuration has commenced, and ought, if possible, to be altogether

dispensed with, being apt in this situation to produce injurious

effects by their irritation. Light dressing is afterwards applied.

On the accession of swelling, heat, and pain, the parts are to be

well fomented with a hot decoction of chamomile flowers, or hops, and

afterwards covered with a warm and soft poultice; and should these

symptoms continue, the fomentation ought to be frequently repeated.

Fomentation and poultice are also the best applications when a

day or two has elapsed between the receipt of the injury and the

patient’s application for cure. The constitutional symptoms are to be

moderated, and may in many instances be averted, by the exhibition of

antimonials and purgatives; and by general bloodletting, when demanded

and authorised by the symptoms, and the state of the constitution.

Punctures or incisions are to be employed according to circumstances,

in order to lessen the vascular congestion of the part, and prevent

the formation of matter, to evacuate it if already secreted, or to

relieve inflammatory tension and promote the formation of pus at the

incised parts, where erysipelatous inflammation is threatened, healthy

suppuration in such circumstances often appearing to be critical. In

many unpromising cases of lacerated scalp, when a great part of the

cranium has been exposed, and partially deprived of its periosteum, a

rapid cure has taken place without the formation of much matter. The

detached scalp, though much torn and bruised, ought not at first to be

removed, it being more prudent to leave nature to determine how much

must be destroyed. After the sloughs, if any, have separated, and

granulation has commenced, the loss of substance is rapidly repaired

in this region, more especially when the patient is young and healthy.

General or partial support, by bandaging, is required in many cases, as

by a handkerchief, split cloths, or a roller applied in various forms.

_Wounds of the Temporal Artery_ are either the result of accident, or

made intentionally for the purpose of abstracting blood; and it may be

here proper to make a few remarks regarding this latter circumstance.

When it is wished to take away blood from the head, no one thinks

of opening the trunk of the temporal artery; its anterior branch is

generally chosen. By some the vessel is first exposed by means of a

scalpel, and then opened with a lancet. But preliminary incisions

are altogether unnecessary. The vessel ought not to be cut entirely

through, and the incision should extend obliquely across its course;

and care is to be taken that the external aperture shall be larger than

that in the cellular tissue involving the artery, as thus the blood

escapes freely, and no risk is incurred of its becoming infiltrated

into the surrounding parts. When the branch is of the ordinary size,

a sufficient quantity of blood is readily obtained from it; but if,

from its small size, or a faulty form of incision, blood does not flow

freely and quickly, a cupping-glass may be applied, and its lower

edge slightly raised. This latter precaution is absolutely necessary,

for if neglected, little or no blood can escape, the artery being

firmly compressed against the cranium by the edge of the exhausted

glass. No other mode of cupping ought to be practised on the temples,

for the cupping by scarification is here both unwarrantable and

unnecessary—unwarrantable, because the cicatrised scarifications

leave an unseemly and permanent mark on a prominent part of the

countenance,—and unnecessary, since there can be no occasion for six

or eight incisions when one is fully sufficient. The bleeding may be

readily stopped, after the requisite quantity has flowed, by a small

graduated compress placed over the wound, and retained by bandages,

which surround the head, and are afterwards twisted and brought

under the chin in order to increase the security. If by these means

the bleeding is not readily restrained, the vessel may be divided

throughout its whole circumference, by entering the lancet at the

original wound, and moving its point laterally. Then compression is to

be again employed, by the assistance of which the natural processes for

closing the divided extremities are speedily accomplished.

When this artery has been injured by external violence, the wound of

the integuments is generally large, and the bleeding profuse. In such

cases, both ends of the vessel must be pulled out by means of forceps,

and tied separately; afterwards the integuments are to be approximated

and supported.

Unpleasant consequences sometimes result from the simple operation of

opening the temporal artery, and occasionally also from accidental

wounds of that vessel. The integuments unite, and may soon heal; but,

from the compression not being sufficient, a small quantity of blood

is insinuated into the cellular tissue, which becomes condensed for a

considerable extent around the wound, and ultimately a sac is formed,

which communicates with the ununited opening in the artery, and is

consequently filled with sanguineous clots; in short, an aneurismal

tumour is formed. For the cure of this untoward occurrence, the artery

may be tied between the heart and tumour, as in the case of spontaneous

aneurism; but in consequence of the free inosculation which exists

between the numerous ramifications of the artery, this measure may

not prove successful, and it will be found necessary, either then

or afterwards, to secure the vessel beyond the tumour. But there is

another mode of procedure. From the tumour being generally small and

circumscribed, excision of the whole of it can be effected easily,

and so as to leave but a slight scar: this operation is not liable to

failure, and is not more severe than the first mentioned. After the

removal of the diseased part by elliptical incisions, the two ends of

the artery are to be included in separate ligatures, and the edges of

the wound kept together.

A more troublesome accident sometimes takes place,—ulceration of, and

over, the vessel, with effusion of serous and purulent fluids into the

surrounding cellular tissue, often to a great extent. A profuse flow of

blood bursts from the ulcerated surface, perhaps twelve, fifteen, or

twenty days after the vessel had been opened, and, if active means are

not speedily adopted, the hemorrhage by its recurrence may prove very

dangerous. In such cases compression is of no avail; the bleeding may

be staid for a time by this means, but upon the circulation becoming

again active, fresh hemorrhage must and does take place; the parts

around are separated and engorged more and more, the blood escapes in

alarming quantities, and the patient is saved only by the occurrence of

syncope. To search for, and make a clean dissection of the wounded part

of the vessel in such cases, is impossible. A long and deep incision

must be made through the swollen and diseased parts in the course of

the arterial branch, and a ligature passed under it, on each side of

the ulcerated point, by means of the common curved suture-needle, or

of one in a fixed handle. The ligatures should be at a considerable

distance from each other, in order that they may surround healthy parts

of the vessel; after they have been firmly tied, all risk of further

hemorrhage is gone. Of course the ligatures should enclose as little

as possible of the parts surrounding the artery. A poultice is perhaps

the best application for a few days, and under its soothing influence

the effects of the continued compression, which had been previously

employed, soon subside. The after applications must be varied according

to the appearances which the part presents.

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