CHAPTER VIII.

FERMENTED DRINKS.

=Properties of Alcohol.=—When a saccharine solution is subjected to the

influence of warmth and moisture, and exposed to the air, it rapidly

undergoes a process of =fermentation=. The most favourable temperature

is about 70° Fahr. The ferment or agent exciting the change in the

sugar is derived from the atmosphere; it is a minute fungus (_torula

cerevisiæ_), the spores of which are constantly floating in the air.

When once fermentation has started, exposure in the air is no longer

necessary; the process continues in closed vessels. The essential

change occurring in the vinous fermentation is that grape sugar

(C₆H₁₂O₆,H₂O) becomes split up into alcohol (C₂H₅OH) and carbonic

acid (CO₂). Thus—

C₂H₆O }

C₂H₆O } Two of alcohol

C₆C₆H₁₂O₆ =

CO₂ }

CO₂ } Two of carbonic acid.

There are other fermentations allied to the vinous. Thus the =Acetous=

fermentation results in the conversion of alcohol into vinegar, as in

the souring of beer or wine. The =Lactic= fermentation leads to the

conversion of milk-sugar into lactic acid, with consequent souring of

the milk.

=Alcohol=, or more correctly ethylic alcohol, is a colourless liquid,

having a pleasant vinous odour, and evaporating rapidly on exposure to

air. It burns with a bluish sootless flame, and is a capital solvent

for resins and other substances.

_Rectified spirit_ is absolute alcohol mixed with 16 per cent. of

water. _Proof-spirit_ is a mixture of 42·7 per cent. by volume of

absolute alcohol, and 57·3 per cent. of water. Thus the ratio of

alcohol to proof-spirit being as 1: 1·76, the amount of alcohol in

any liquid being given, the amount of proof-spirit can readily be

calculated. The fermented drinks containing alcohol may be classed as

(1) malt liquors, (2) wines, and (3) distilled spirits. The relative

properties of these will be considered afterwards; in the next two

sections will be considered the effects of diluted alcohol in whatever

form it is taken.

=Effects of Moderate Doses of Alcohol on the System.=—In studying the

physiological effects of alcohol, one has to guard against the fallacy

that these are the same, only differing in degree, whatever the dose

may be. The effects of large doses of alcohol are almost exactly the

reverse of those produced by small doses. It will be necessary to

define, therefore, what we mean by a moderate dose. By a moderate

dose, we understand the amount of alcohol which can be taken without

any alcohol being eliminated in the urine. Dr. Anstie found that 1½

ounces, that is three tablespoonsful, of absolute alcohol, taken in

twenty-four hours, caused its appearance in the urine; and Dr. Parkes

and Count Wollowicz obtained almost precisely the same result. Anything

below some quantity between 1 and 1½ fluid ounces per day can be

disposed of in the system, and is probably oxidised like ordinary foods.

The amount of alcohol, in the form of alcoholic beverages,

corresponding to this =maximum dose= of absolute alcohol is

approximately as follows:—

One imperial pint (20 fluid ounces)

of bottled beer (5 per cent. of alcohol).

One tumblerful (10 „ „ ){of claret, hock, and}

{other weaker wines } (10 „ „ ).

2½ glasses (5 „ „ ){of port, sherry, and}

{other strong wines } (20 „ „ ).

One glass (2 „ „ )of brandy or whiskey (50 „ „ ).

It will be understood, therefore, that in describing the effects of a

moderate amount of alcohol on the system, an amount below 1½ ounces

of absolute alcohol per day is meant, freely diluted, and taken as a

rule with meals.

1. =Effect on the Stomach.=—In very small quantities, alcohol seems

to stimulate digestion in the same way as mustard. But like all other

artificial helps to digestion, it is best avoided in the healthy

condition.

2. The =Effect on the Liver= is similar to that on the stomach—a

temporary redness and congestion being produced; this effect soon

disappearing if the dose is small and well diluted. But in all cases

where there is a tendency to biliousness, even small doses of alcohol

are injurious.

3. The =Effect on the Heart and Blood-Vessels= is first to increase

the force of the heart’s action and the rapidity of the pulse. The

stimulation of the heart is rapidly followed by a universal dilatation

of the small arteries of the body, which diminishes the blood-pressure.

Parkes and Wollowicz found that the daily administration of from 1 to

7½ ounces of rectified spirit raised the pulse rate by ten beats

per minute, as compared with other periods; and that this effect was

followed by a period of depression in which the beat was both slower

and feebler than usual.

4. The =Effect on the Nervous System= varies. In persons unaccustomed

to its effects, even small doses dull the power of thought and the

rapidity of perception, owing to the paralyzing effect which it exerts

on nerve cells. In most cases, however, it at first produces increased

rapidity of thought and excites the imagination, though even here

it makes it more difficult to keep to one train of thought. This is

clearly owing to the more rapid circulation of blood through the brain.

Dr. E. Smith’s experiments show that it diminishes the acuteness of

the senses. Its influence even in dietetic doses, on the capacity for

mental work, is slightly to diminish it.

5. The =Effect on the Muscular System= is never beneficial. Even when

only small quantities are taken, the power of controlling delicate

movements is slightly diminished. For persons engaged in laborious

occupations, a small quantity does not produce much apparent effect,

but where the quantity exceeds two fluid ounces per day the capacity

for strong and sustained muscular work is manifestly lessened (Parkes).

This effect is probably due partly to the dulling of the nervous

system, rendering the muscles less amenable to the will, and partly to

the over-excitation of the heart causing palpitation and breathlessness.

6. The =Effect on Metabolism= is to diminish it, thus favouring the

deposit of fat in the tissues. It acts as a poison to the protoplasm

of the cells of the body, diminishing their power to break down the

floating nutriment, especially fat and carbohydrate.

The =Effect on the Temperature= is to lower it; but unless the dose

is excessive, this effect is hardly appreciable. The resistance to

excessive cold is diminished by even moderate doses of alcohol, still

more by large doses. In the Arctic regions, this has been abundantly

proved. This effect is produced, notwithstanding the fact that alcohol

becomes oxidised in the system. The dilatation of the surface blood

vessels leads to a greater loss of heat than that produced by the

oxidation of the alcohol.

EFFECTS OF IMMODERATE DOSES OF ALCOHOL ON THE SYSTEM.—Bearing in mind

the definition given of a moderate dose, one is bound to admit that

a large number of individuals exceed this amount daily, apparently

without any very serious results. The system becomes habituated to

large doses, and if the occupation is a laborious one, they may in part

be oxidised in the system. Such, however, are exceptional cases. In

the majority of cases evil results are by no means confined to those

who indulge in very large quantities of alcohol at varying intervals.

In fact these very often escape comparatively free, while others who

never take a quantity sufficient to incapacitate them for their work,

are sowing the seeds of chronic and oft incurable disease. The labourer

who has a drinking bout at intervals is thoroughly nauseated; and the

condition of liver and stomach induced, enforces abstinence on him

for a time sufficient to bring his organs back to a normal condition;

while the city merchant who indulges more moderately, but whose organs

are almost continuously impregnated with alcohol, becomes gouty and

prematurely old.

The =Stomach= may become acutely inflamed, when a large dose of alcohol

is taken. The chronic irritation of alcohol, especially when taken

apart from meals, causes atrophy of the walls of the stomach, and a

change analogous to that in the liver.

The =Liver=, when alcohol is daily taken immoderately, becomes

seriously diseased. In some cases it becomes large and fatty; in others

the chronic irritation excites an overgrowth of fibrous tissue between

the lobules of the liver, which, gradually shrinking, squeezes the

liver cells and causes them to atrophy, at the same time obstructing

the small branches of the portal vein in the substance of the liver.

The consequence of this obstruction to the flow of blood through the

liver is that all the organs from which the portal vein brings blood

become overloaded with blood, and vomiting of blood and dropsy of the

abdomen occur at a later period.

The =Lungs= are irritated to a less extent by alcohol in large doses.

The tendency to chronic bronchitis is increased, followed by emphysema,

and sometimes an overgrowth of fibrous tissue (cirrhosis) like that in

the liver occurs.

The =Heart and Blood-vessels= tend to become diseased, owing largely to

the gouty condition of system developed.

The =powers of Metabolism= are diminished. Corpulence is, consequently,

a common result of alcoholism. There may also be fatty deposit in

the internal organs, such as the heart. This must not, however, be

confounded with a much more serious condition, fatty _degeneration_

of the heart, in which the substance of the muscular fibres becomes

partially converted into fat, and which also is sometimes due to

alcoholism.

The =Nervous System= is more prone to suffer in chronic alcoholism

than any other part of the body, except perhaps the liver. The first

effect of a large dose of alcohol is to stimulate the nervous system,

as already described. This is followed by a dulling of the nervous

faculties, which comes on rapidly in proportion to the amount taken.

The phenomena of _intoxication_ are unhappily too familiar to require

description, mental incoherence and muscular incoordination (lack of

control over the muscles) being the most prominent features.

When the dose of alcohol is still larger, a condition of profound

unconsciousness is produced (_coma_), which may be difficult to

distinguish from other forms of unconsciousness.

=Delirium Tremens= is another nervous condition, which may rarely

follow a single debauch, but much more commonly affects the chronic

toper. In some cases the immediate exciting cause is a mental shock, or

lack of food, or a surgical injury. Alcoholic subjects suffering from

any acute disease are liable to this form of delirium, and their chance

of recovery is greatly diminished.

=Insanity= of a more prolonged character than that characterising

delirium tremens is an occasional result of alcoholism.

Besides the nervous diseases already named, a chronic thickening of the

membranes covering the brain and spinal cord, gradually progressing

and finally fatal, is often the consequence of prolonged alcoholic

indulgence.

=Various Degenerative Diseases= are produced by alcohol. It has been

well called by Dickinson the very “genius of degeneration.” Such

degenerations are by no means confined to the intemperate; they are

seen in those who are of what would usually be considered moderate

habits. The stomach, liver, lungs, and probably the kidneys, are the

main organs to suffer in this way. It is probable that the effect on

the kidneys only occurs when a gouty condition is developed. In all

these cases there is an overgrowth of fibrous tissue, with atrophy of

the proper gland structures.

=Gout= is the common nemesis of those indulging in alcoholic beverages,

more especially wine and beer, due to the excessive formation or

retention of urate of soda in the body. This produces inflammation of

the joints, and other evils—among them the gouty kidney, named above,

which is always ultimately fatal. Rigid arteries are likewise commonly

due to alcoholism and gout. If one of these bursts in the brain,

apoplexy results.

=Longevity= is diminished by immoderate indulgence in alcohol. The

statistics of Temperance Insurance Societies, show much better results

among teetotalers than among moderate drinkers. It is only fair to

add that although the latter are supposed to consist of moderate

drinkers—and particular enquiries are always made on this point before

insurance—it is probable that a large proportion of them exceed 1½

ounces of alcohol per day. Making due allowance for this fact, the

statistics show a great superiority in the expectation of life of

teetotalers.

=Factors Modifying the Effects of Alcohol.=—1. =Age and Sex.=—Until

adult life is reached, total abstinence from alcohol should be

enforced. The delicate nervous system of children is easily disturbed

by it, and it appears in some measure to retard growth. Another

argument against giving alcohol before adult age is reached, is still

more important. It is at this period of life that habits are chiefly

formed, and a craving for alcohol may be insidiously produced, destined

to have most baneful results.

Old people, if ordered spirits for medical reasons, should drink them

well diluted.

Women are much more easily affected by alcohol than men, and if they

acquire the habit of excess, the hope of reformation is even less than

with men.

2. =Exercise= has a most important influence in modifying the effects

of alcohol. Those of sedentary occupations and living in towns, cannot

oxidise as much as those engaged in active out-door work, and are

consequently much more prone to suffer. A game-keeper in the Scotch

Highlands may possibly live to a good old age, notwithstanding the fact

that he consumes an amount of whiskey that would have sent a sedentary

man to his grave in the course of a few years.

3. =The Condition of the Stomach= has also great influence. When

the stomach is empty, alcohol produces at once a powerful reflex

stimulation of the heart, and becomes quickly absorbed into the

circulation. Thus intoxication may be produced by a quantity that would

have had little effect if taken with a meal.

4. =The State of Concentration or Dilution= modifies greatly the action

of alcohol, the local action on the stomach and the reflex stimulation

being much greater than when it is concentrated, and injurious effects

being much more likely to occur.

5. =Cold and Heat= modify the action of alcohol. A smaller quantity

of hot spirits and water will intoxicate than of cold; the heat

stimulating the heart, and so making the absorption of the alcohol more

rapid. A glass of hot spirits and water will often cause sleep, by

drawing the blood towards the abdominal organs. The fact that persons,

who have been drinking spirits in a warm room, on going out into the

cold air become suddenly intoxicated, seems opposed to what has been

already said. But probably this is due to the cold causing contraction

of the arteries of the skin, and so driving more of the blood loaded

with alcohol to the internal organs and the brain (Brunton).

6. =Mental Occupation= has some influence in modifying the effects of

alcohol. Topers have found that if they try to converse during their

debauch—the conversation implying increased functional activity of the

brain, and therefore a freer circulation of blood in it—intoxication

occurs much more readily, than when the mind is not active.

7. =Disease= modifies greatly the effects of alcohol. In some diseases,

as in inflammation of the lungs and in fevers, it can be given in large

quantities without producing intoxication; and in these conditions it

lowers the temperature. In other diseases, especially gout and kidney

disease, its use is nearly always followed by bad results.

=The Advisability of Alcohol as an Article of Diet in Health.=—In

dealing with this difficult point, two sets of facts require

consideration, those obtained as the result of =Physiological=

observations (see page 56), and those which are the result of

=Experience=. There can be no doubt that the former are much more

reliable than the latter. Experience is very prone to give fallacious

results, especially when questions of appetite are concerned. In

making a trial of abstinence, the mistake has been commonly made of

only prolonging the investigation for a few weeks, and then comparing

results. Such a method is, however, very unfair, and is certain to lead

to an unreliable conclusion.

The records of experience under certain conditions have, however, been

so extensive, as to lead to trustworthy results. It has been abundantly

proved that prolonged muscular work is best undergone during total

abstinence from alcohol; and that the extremes of heat and cold and the

exposure and exertions of marching armies, are best borne under similar

conditions.

The artificial character of town life is commonly adduced as an

argument for the moderate use of alcohol. In the case of healthy

workers, this does not hold good; many of our hardest workers and

thinkers take no alcohol.

The universality of the habit of taking stimulants is a curious

argument on the same side, though if the habit be bad, this can be no

more reason for continuing it than can the prevalence of vice be an

excuse for indulgence in it.

The two chief physiological points bearing on the advisability of

alcohol as a part of one’s daily diet are—its =food properties=, and

its effect on the appetite and digestion.

It has been already stated that a quantity of alcohol under 1 or 1½

ounces may become oxidised in the system, and may thus form a source of

heat. But in all probability, although it may be regarded as a food,

it is a most inconvenient one, inasmuch as it diminishes the oxidation

of other foods. It has been aptly compared in this respect to

sulphur, which is an oxidisable material, but which, when it is burnt

in a chimney, in which the soot is on fire, will put an end to the

combustion of the latter. Its value as a food, under normal conditions,

is practically nil.

Its =Effect on the Digestive Organs= is three-fold. (_a_) The contact

of alcohol with the mucous membrane of the mouth and stomach, acts as a

reflex nervous stimulus, which in moderation excites an increased flow

of gastric juice. (_b_) It also increases the activity of the movements

of the stomach. In cases of weak digestion, therefore, small doses of

alcohol may, at times, be useful. (_c_) The effect of alcohol on the

food taken varies with its degree of dilution. Concentrated alcohol

coagulates albumin, and so stops digestion; largely diluted alcohol has

no such effect.

The late Dr. Parkes, the greatest authority on the dietetic use of

alcohol, has summarised the argument as to the dietetic use of alcohol

as follows:—

“But what, now, should be the conclusion as to the use of alcohol

in health after growth is completed? Admitting the impossibility

of proving a small quantity to be hurtful, and at the same time

acknowledging the dangers of excess, there arises an argument which

seems to me somewhat in favour of total abstinence. No man can say when

he has passed the boundary which divides safety from harm; he may call

himself temperate, and yet may be daily taking a little more than his

system can bear, and be gradually causing some tissue to undergo slow

degeneration. He may be safe, but he may be on the verge of danger.

“This uncertainty, coupled with the difficulty at present of saying

what dietetic advantage is gained by using alcohol, seems to me rather

to turn the scale in favour of total abstinence instead of moderate

drinking. But if any one honestly tries, and finds he is better in

health for a little alcohol, let him take it, but he should keep within

the boundary line, viz., that 1½ ounces of pure or absolute alcohol

in twenty-four hours form the limit of moderation. I do not then think

he can do himself any harm.”

=The Varieties of Fermented Drinks.=—The three chief kinds of alcoholic

beverages are malt liquors, wines, and ardent spirits. In addition, we

may mention cider and perry, which are the fermented juices of apples

and pears respectively; and koumiss, which the Tartars prepare by

fermenting mare’s milk, though it may also be made from the milk of

other animals.

All =Beers=, =Ales=, and =Porters= are prepared from malt, which is

the germinating grain of barley. The fermentation of the sugar in the

barley produces alcohol, the amount of which varies in different cases.

In Pilsener beer it is 3½ per cent. of absolute alcohol; in stout

and porter 5 to 6 per cent. The hop which is added to the fermenting

barley, gives to beer its characteristic bitterness.

=London Porter= is coloured with black or roasted malt; =stout= is only

a stronger form of porter. Bottled ales are generally stronger than

those on draught, and being slightly effervescent, may agree better.

The effect of alcohol in beer is modified by the _hops_, which help in

producing drowsiness. Beer has a marked tendency to produce obesity,

more so than any other alcoholic beverage. Its influence in the

production of gout is also very great.

=Substitutes for Malt= have been largely used. Thus by the action of

sulphuric acid on starch, an artificial form of sugar is produced,

which is largely used in place of malt for making beer. Many recent

cases of poisoning by arsenic have been traced to the use of impure

sulphuric acid in manufacturing this form of sugar.

The detection of arsenic in organic liquids requires great care, as so

many compounds of arsenic are volatile, especially in the presence of

chlorides, as in beer. To _detect arsenic in beer_ a pint of the beer

is evaporated to dryness, and treated with 20 c.c. of strong sulphuric

acid, heated, and 20 c.c. of strong nitric acid added drop by drop.

Violent action occurs: if possible 20 c.c. more of nitric acid are

worked in. Transfer the liquid to a small flask, and expel the nitric

acid by boiling. By this means all chlorine is expelled, the arsenic

is oxidised and the organic matter destroyed. SH₂ gas is now passed

into the acid liquid for some hours, the precipitated sulphur and any

sulphide filtered off and extracted with ammonia, which dissolves any

sulphide of arsenic. The liquid so obtained is subjected to Marsh’s

test. (See page 216.)

In the making of beer from malt, the first stage is to malt the barley,

_i.e._ leave it spread on floors for ten days after soaking. This

allows germination to take place, in which process the insoluble starch

is converted into starch, dextrine, maltose and glucose. After the

dried malt has been screened to break off the sproutings, the brewer

places it in the mash-tub, with water, at a temperature of 160° F. This

completes the transformation of the starch into glucose. The =wort= is

now boiled to stop the process, and the albumin from the grain is thus

coagulated. Hops are added at this stage. The boiled liquid is passed

into shallow vessels and cooled. The proper temperature for “top” yeast

is 60° F., for “bottom,” or Bavarian yeast, a much lower temperature is

desirable. When the desired temperature is reached, the liquid is run

into the fermenting tun along with yeast. The varieties of beer are due

in part to the degree of completeness of fermentation of sugar allowed.

If too complete, the beer does not keep well.

=Wines= are produced by the fermentation of the juice of the grape.

The wine produced may be bottled before or after fermentation is

complete; in the former case, an effervescing wine is produced, such as

the sparkling wines of the Rhine and the Moselle, or champagne. When

the sugar is nearly all fermented a _dry_ wine is obtained, of which

Bordeaux and Burgundy, Hock and Moselle, are examples.

The difference in colour between red and white wines is produced by

allowing the juice in the former to ferment in contact with the skins,

from which the colouring matter is extracted by the alcohol. Both red

and white wines may be obtained from either red or white grapes. From

the skins also are extracted a salt of iron, and a peculiar form of

tannin. Tartaric and acetic acids, and tartrate of potass, are present

in varying quantities in wines; in old wines the tartrate separates as

bitartrate of potass, forming with tannin and colouring matter the

“crust” of port and other wines. The “bouquet” of wines is due chiefly

to certain volatile bodies, such as pelargonic ether. The proportion

of alcohol in wines varies from 6 to 14 per cent. As fermentation is

stopped by the presence of 14 per cent. of alcohol, any larger amount

of alcohol than this must have been added to the wine.

Wine, like beer, has a strong tendency to produce gout, especially

the sweet and strong wines. It has not, however, the same tendency to

induce obesity.

=Spirits= differ from the two last groups, to begin with, in the amount

of alcohol they contain. Thus, English beers contain from 3 to 6 per

cent., German beers from 2 to 5 per cent., wines from 8 to 20, and all

kinds of spirits from 37 to 58 per cent. of alcohol. They differ in

the absence of the bitter principle of beer and much of the salts and

sugar and ether of wines. They are all prepared by the distillation

of some previously fermented liquor. =Brandy= ought to be made by the

distillation of wine; and then contains, besides alcohol and water,

small quantities of acetic, œnanthic, butylic, and valerianic ethers.

But much of the brandy sold is simply made from potato spirit, by the

addition of acetic ether, burnt sugar, etc. The starch of potatoes

is converted into dextrin and dextrose by dilute acids, and then

fermentation allowed. By the use of patent stills, all bye-products

can be separated, a fairly pure alcohol known as _silent spirit_ being

produced. This is largely employed in manufacturing spirits and in

fortifying wines.

=Whiskey= is prepared from malted barley, or from a mixture of grains,

to which a sufficiency of malt to convert their starch into sugar has

been added. In _grain whiskey_ the distillation is effected by steam

in a patent (Coffey’s) still, which separates most of the bye-products

(fusel oil, etc.) from the spirit. In _malt whiskey_, distilled in the

old-fashioned pot-still, these bye-products are not separated.

The improvement of whiskey effected by keeping is not due (Bell) to

the diminution of fusel oil. Such a diminution does not occur. The

percentage of alcohol diminishes by keeping, 6 to 8 per cent. proof

spirit being lost by five years’ storage in wood. “Fusel oil” is a

mixture of alcohols of higher boiling point than ethylic alcohol

(amylic, propylic, etc.). Even in a bad whiskey not more than 1∕10

per cent. of fusel oil is present (about one grain in a glassful).

Experimentally no marked effects have been produced by fusel oil, when

it is less than 1 per cent. Possibly the presence of furfurol, of

which there is a trace in malt whiskey, which disappears on keeping,

may partially explain the disagreeable flavour of new whiskey. But it

is fairly clear that those who argue that it is _bad_ whiskey and not

_good_ whiskey which does harm are speaking without knowledge. It is

not the quality but the quantity of whiskey which is responsible for so

much moral and physical evil.

=Gin= and =Hollands= are obtained from barley, and flavoured with

juniper berries and other materials. The oil of juniper stimulates the

urinary excretion.

=Rum= is obtained by the distillation of molasses, and is usually

kept for a long time in oak barrels. It is said thus to acquire more

astringent matters than other spirits contain.

The =legal limits= of dilution of whiskey, brandy and rum is down to 25

degrees under proof, and of gin down to 35 degrees under proof. (For

definition of proof spirit, see page 55). The amount of alcohol in an

alcoholic liquor is determined by distillation of 100 c.c., making up

the distillate to 100 c.c. by the addition of distilled water, and then

taking the specific gravity of a portion of this liquid by the aid of

the specific gravity bottle. The percentage of alcohol corresponding to

a given specific gravity is given in tables prepared for this purpose.

Prolonged indulgence in spirits produces the various organic diseases

already described, and unless well diluted they are more harmful than

beers or wines. They differ from wines and beers in not tending to

produce gout, and from beer in not leading to obesity.

Hygiene: a manual of personal and public health (New Edition) · 第 8 / 48 章