CHAPTER VII

THE ALCOHOLIC PSYCHOSES

According to Tuke,[213] one of the oldest of the Egyptian papyri in the

British Museum (Papyrus Sallier I) makes the following very interesting

reference to alcoholism:— "Whereas it has been told me that thou hast

forsaken books, and devoted thyself to pleasure; that thou goest from

tavern to tavern, smelling of beer, at the time of evening. If beer

gets into a man it overcomes his mind.... Thou knowest that wine is an

abomination, that thou hast taken an oath that thou wouldst not put

liquor into thee. Hast thou forgotten thy resolution?" It is difficult

to realize that this refers to one of the earliest periods of recorded

history. Hebrew, Greek and Roman literature are prolific in equally

significant testimonials to the antiquity of alcohol as an intoxicant.

It was referred to at considerable length by Aristotle, Plutarch and

Hippocrates. That Haslam appreciated the important relation existing

between alcoholism and mental disorders is shown by the following

comment on this subject written in 1808:—"Thus a man is permitted

slowly to poison and destroy himself; to produce a state of irritation,

which disqualifies him from any of the useful purposes of life; to

squander his property among the most worthless and abandoned; to

communicate a loathsome and disgraceful disease to a virtuous wife; to

leave an innocent and helpless family to the meagre protection of the

parish. If it be possible the law ought to define the circumstances

under which it becomes justifiable to restrain a human being from

effecting his own destruction, and involving his family in misery and

ruin. When a man suddenly bursts through the barriers of established

opinion; if he attempts to strangle himself with a cord, to divide his

large blood vessels with a knife, or swallow a vial full of laudanum,

no one entertains any doubt about his being a proper subject for the

superintendence of keepers; but he is allowed, without control, by a

gradual process, to undermine the fabric of his health and destroy the

property of his family."

Curiously enough the word alcohol is of Arabic origin and was employed

originally to describe a powder used in applications to the eyebrows

for cosmetic purposes. It was subsequently used for centuries as

referring to a fine powder of any kind, as is shown by the writings

of Paracelsus and others. The chemical composition of alcohol was not

known until 1808, when it was described by Lavoisier. On the other

hand, Salvatori in 1817 and Hufeland in 1818 referred to dipsomania

as a disorder due to alcoholism. Esquirol, Trélat and other early

writers included it in the "partial" insanities. Morel described it

as an impulsive form of "délire émotif" and looked upon it as an

hereditary condition. It has been classified with the periodical

insanities and even as a form of melancholia. Magnan saw in it an

episode of the insanity of degeneracy. Magnus Huss was responsible for

the introduction of the term "chronic alcoholism" as descriptive of a

pathological condition in 1852.

It is said that Caelius Aurelianus protested against the use of

intoxicants in the treatment of the insane. Notwithstanding this early

reference to a question of such importance, and the inauguration of

the great temperance crusade which began in 1808, it has been shown

by Tuke[214] that alcoholic beverages were issued in a routine way to

patients and employees of the British asylums for the insane less than

forty years ago. "Thirty superintendents hold that they have observed

very beneficial results from the course pursued. The improvement

usually refers not only to the patients, but to the discipline of the

asylum." The cost of beer supplied to the inmates at the Glamorgan

Asylum at one time was reported to be as high as two hundred and sixty

pounds per year (Tuke). Beer was not discontinued as a regular article

of diet for patients at the Derby Asylum until 1884.

In 1844 Flemming[215] in his classification of psychoses mentioned

the following forms of alcoholic insanity:— Ferocitas et morositas

ebriosorum, anoësia e potu, anoësia semisomnis, delirium tremens, and

mania à potu. Clouston[216] described acute and chronic forms—mania à

potu, dipsomania, alcoholic dementia and degeneration. Krafft-Ebing[217]

speaks of hallucinations of the inebriate, delirium tremens, alcoholic

melancholia, mania gravis potatorum, hallucinatory insanity, alcoholic

paranoia, alcoholic paralysis and epilepsy. Delirium tremens he

ascribes either to repeated excesses (à potu nimio), abstinence (à potu

intermisso), insufficient nourishment, violent emotions, pneumonia and

other acute diseases, loss of sleep, injuries such as fractures, etc.

By hallucination of the inebriate (sensuum fallacia ebriosa) he refers

to the transitory hallucinations of the constant drinker. Meyer[218]

has described an alcoholic constitution "as shown by the lachrymose,

prevaricating, jealous deterioration of the drinker."

Stöcker,[219] after an extended study of a considerable number of

cases, came to the conclusion that alcoholism is the result of a

constitutional condition but not the cause of characteristic psychoses.

Often, as was also shown by Bonhöffer, it is to be attributed to

a psychopathic personality either acquired or congenital. The

psychoses represented by the group of patients he examined included

manic-depressive insanity, dementia praecox, hysteria, epilepsy and

other miscellaneous conditions. He refers to dipsomania as an epileptic

equivalent. His conclusions in brief were as follows:—"Chronic

alcoholism in the first place is a symptom of a mental disease. It may,

however, so exaggerate stationary epilepsy, chronic mania, dementia

praecox, etc., which hitherto were latent, and perhaps would remain

still latent without alcoholic abuses, that it may lead to a sudden

outbreak of a turbulent disease manifestation. It may also give these

diseases peculiar traits or a peculiar coloring for some time, which

above all, may appear as the most striking phenomena, and thus cover up

the symptoms of the fundamental disorder. Furthermore, it may, also,

on the basis of this constitutional disease give rise to independent

clinical pictures." Karpas[220] in commenting on this says: "One must

remember that cravings play important rôles in our mental life. Some

of our cravings are gratified; others find realization in our dreams;

still others are repressed and compensated. In fact, our mental

life is nothing but a readjustment, of complex reactions. The poet

finds recourse in his phantasies; the philosopher gives vent to his

theoretical speculations; the scientist resorts to his inventions and

hypothetical theories; the well balanced, normal individual seeks

readjustment in healthy activities,—art, literature, science,

occupations, sport, etc., etc. But the individual with a poorly endowed

constitution finds refuge in neurosis, psychosis, alcoholism, drugs,

and other vicious habits. We must recognize that alcoholism is nothing

but a compensation for a complex, the fulfillment of which was denied

by reality."

Kraepelin[221] described acute and chronic alcoholism, pathological

intoxication, alcoholic jealousy, delirium tremens, Korsakow's

psychosis, alcoholic hallucinoses, paralysis and pseudo-paresis. In

acute intoxication Kraepelin finds an inhibition of apprehension,

mental grasp and the elaboration of outer impressions with a

stimulation of the release of volitional impulses. A clouding of

consciousness develops, associated with emotional excitement and a

weakness of will power. Perception and mental reactions are delayed

and their accuracy decreased on mental tests. The discrimination

between louder sounds is uncertain, although the sensitiveness to

lighter sound impressions is increased as in the ether narcosis.

Busch found a limitation of the field of vision. The preservation of

memory impressions is imperfect. A solution of mathematical problems

shows a lowered mental capacity for work. The association of ideas

and composition of sentences is delayed. There is a tendency to

new word formation, phrasing and rhyming, with a certain amount of

distractibility. Goal ideas are often missed, and consistent, orderly

thought is not possible. Expression is rapid and impulsive, and is

often characterized by a loud tone of voice.

After larger amounts of alcohol psychomotor activities are interfered

with as shown by the writing, and ataxia appears. The reflexes show an

increased muscular tension. Physical strength is markedly lowered,

although it may be increased for a very short time. Alcohol even in

small amounts interferes with productive mental processes. Ideas lose

in clearness and sharpness, fatigue occurs earlier and efficiency and

judgment are impaired. Still larger amounts retard apprehension and

comprehension and the intoxicated person no longer knows what is said

to him. All ability to control his conduct is lost. There is a tendency

to repetition in speech, rhyming and jargon. Capacity for mental work

is finally entirely gone and memory becomes confused. Psychomotor

stimulation and excitement appear early, terminating finally in

weakness. Emotional trends, at first happy and cheerful, are usually

irritable, later with outbursts of anger. Sexual excitement often

appears. Various physical disturbances have been described.

In the pathological or complicated intoxications as described

by Kraepelin, unusual emotional disturbances such as violent

excitements occur. Anger or anxiety may develop with a clouding of

the consciousness, and lead to uncontrollable rages with impulses to

assault and kill. The most marked excitements occur in epileptics.

The outburst is usually sudden in these cases and is followed by the

most senseless and unjustifiable acts. Occasionally suicide is the

result. In hysterical and psychopathic individuals alcohol may cause

serious emotional disturbances, with clouding of consciousness or even

delusion formation. Chronic drinkers are very likely to have abnormal

symptoms at times. They often show a marked irritability followed

by a pathetic and tearful mood. Abusive treatment of members of the

family, jealousy, threats and violence are not uncommon. Delirious or

anxious states with persecutory ideas and hallucinations are sometimes

observed. These may exist only during intoxication. Alcohol often

produces extreme excitements in cases of manic-depressive insanity,

general paresis and dementia praecox. Pathological changes of various

kinds have been reported. In acute alcoholism Nissl found a destruction

of cortical cells in some cases and a disappearance of the stainable

lumps in others. The nuclei of the neurones were shrunken and sometimes

displaced.

Various tests have demonstrated the limited mental capacity of the

chronic alcoholic. Will power is greatly reduced and fatigability

increased. Memory and attention are affected and falsification of

the past may occur. The patient learns nothing new and forgets the

important things. All productive efficiency is gone and interest is

lost. Weakness of judgment and loss of memory capacity lead to delusion

formation. These often take the form of ideas of jealousy. Delusions

of persecution, poisoning or grandeur may appear from time to time.

Frequently there are genuine hallucinations. Some cases terminate

finally in mental enfeeblement. Emotional changes are common in the

chronic drinkers. The alcoholic humor is characteristic. The capacity

for taking things seriously has been lost and there is a tendency to

undue levity, often with a marked feeling of self-satisfaction. Some

individuals, however, become moody, irritable or dull. Occasionally

anxious states appear, frequently with suicidal attempts. One of the

common symptoms of this condition is an extraordinary irritability

after drinking. This leads to quarrels, assaults and violence.

Consideration for others is completely lost. These attacks are often

followed by remorse. A prominent and significant feature of the

disease is the marked moral deterioration. All affection for family

and children may be lost. Selfishness is pronounced and the patient

spends all of his money for drink. Sexual excitement is sometimes

an important symptom. With all of this there is a constant craving

for alcohol. The patients have no insight into their condition and

attribute their headache and tremors to overexertion, etc. They always

deny using much alcohol and are absolutely untruthful on this subject.

Overwork necessitates drinking, or it only happens after a death in the

family, etc. Will power deteriorates rapidly. These individuals often

commit crimes and come into conflict with the law. Gastritis, cirrhosis

of the liver and numerous other diseases complicate the situation.

Dizzy spells and headaches are common, as well as tremors of the

tongue and fingers. Neurotic involvements are noted, with anesthesias,

hyperesthesias, paresthesias, and muscular atrophies as well as speech

defects. Epileptiform attacks are not infrequent in chronic alcoholism,

and were found in ten per cent of Kraepelin's cases. His investigations

showed that eleven per cent of the beer drinkers in Munich had

convulsions. Combinations of epilepsy and hysterical manifestations

with chronic alcoholism are not at all unusual. Rybakoff found a

hereditary taint in 66.6 per cent of his cases while Moli reported only

forty-seven per cent. Heredity was found to be a factor in thirty-seven

per cent of Kraepelin's Heidelberg cases and in seventeen per cent

of those at Munich. He describes various pathological findings in

chronic alcoholism. Meningitis with hemorrhagic membranes is common.

The convolutions are atrophied and the ependyma of the ventricles

thickened. Pigmentary deposits similar to those of senility are found

in the cells and vessel walls. There is an increase of both neuroglia

cells and fibres. Hemorrhages are occasionally found in the central

gray matter.

When the suspicions of the chronic alcoholic lead to well defined

delusions Kraepelin speaks of "alcoholic jealousy" as constituting a

distinct psychosis. The patient sees in almost everything evidences of

infidelity on the part of his wife and is often inclined to question

the legitimacy of his own children. Assaults and violence are frequent

occurrences. Occasionally genuine hallucinations accompany this

condition. Suicidal and homicidal attempts are not uncommon.

The onset of delirium tremens, first described by Thomas Sutton in

1813, is characterized by states of anxiety, fear, insomnia with

disturbing dreams, sensory excitement, hyperesthesias, flashes

of light, etc. The development usually is sudden, with a loss of

attention, disturbance of apprehension, restlessness, distractibility,

numerous hallucinations of the different senses, illusions, clouded

states with disorientation, tremors and ataxia. Touch, pain and

temperature sensations, according to Kraepelin, are undisturbed.

The field of vision is sometimes narrowed. Recognition of colors is

uncertain. There is a marked disturbance of the equilibrium, suggesting

some lesion either of the eye muscles or of the labyrinth. A decided

lengthening of the reaction time in associations has been shown by

various observers. Sensory hallucinations are common. The ability

to read correctly is entirely lost and what is read is meaningless.

A paraphasic form of reading has been described by Bonhöffer. The

attention cannot be held for any length of time. A dreamy clouded state

is characteristic. Disorientation is usually complete in the severe

cases. The hallucinations and illusions are very marked and sometimes

even suggest moving pictures to the patient. Hallucinations of vision

are more common than those of hearing. Peculiar skin sensations such as

feelings of electricity are spoken of. Hallucinations may be induced

by pressure on the eyeball and sometimes by suggestion. There is

occasionally a confusional form of speech suggesting dementia praecox,

with a tendency to coin new words and employ entirely meaningless

terms. Although consciousness is not always entirely clouded, events

transpire as in a dream, always confused by innumerable hallucinations.

An occupation delirium is common, the patient imagining himself busy

at his customary work. Delusional ideas regarding everything in his

surroundings are frequent. Ideas of grandeur sometimes occur. Never,

according to Bonhöffer, is there a complete disorientation as far as

personality is concerned. The patient always knows who and what he is.

Complete mental confusion is not the rule. Distractibility is usually

very well developed. Bonhöffer found an inability to supply omitted

words and syllables from well known phrases and memory for test words

and numbers was impaired. Articles read are repeated with many changes

and omissions. Memory for remote events is usually well preserved.

Sometimes there is a falsification of the past. The mood is anxious,

fearful, seldom irritable, at times actually humorous. Cheerfulness and

fear of death occasionally alternate.

The course of the disease is characterized by great restlessness often

with a tendency to talkativeness. There is, however, no flight of ideas

or rhyming. Delusions of persecution occur in some cases. Anesthesias,

hyperesthesias, paresthesias, hypalgesias and sensitiveness of nerves

and muscles are noted. Romberg's sign is present in some instances.

Speech is often ataxic and paraphasic, and in advanced eases entirely

meaningless. Tremors of the tongue and fingers are very characteristic.

Writing is very much affected as a result. Epileptiform convulsions

sometimes occur. Rarely focal symptoms, facial paralysis and hemiplegia

appear for a short time. Reflexes are increased and ankle clonus

occasionally appears. Defective papillary reaction and unequal pupils

may be found, with diplopia and muscular weakness. Sleep is seriously

interfered with. Bodily weight is reduced and blood pressure lowered.

The temperature is usually elevated and the pulse accelerated. Albumen

and sometimes sugar is present in the urine. The delirium often stops

as suddenly as it begins, terminating in sleep, the patient being

clear when he wakes. The memory of events is not well retained on

recovery. The delirium may, however, become chronic and last for

months. Some cases terminate in a hallucinatory feeblemindedness.

This is likely to occur in psychopathic individuals. Hallucinations

of hearing are more common in such conditions. People read their

thoughts and influence their minds. They are subjected to hypnotism

and electricity. The delusional ideas may be of a sexual nature or

grandiose in character. The mood may be anxious or irritable. Suicidal

tendencies sometimes appear. Later a humorous trend is often noted.

Tremors and other neurological symptoms sometimes occur. Bonhöffer

found at autopsy a considerable fibre loss in the central convolutions,

the cerebellum and the column of Goll. In the large pyramidal and

motor cells of the anterior central convolution the processes were

deeply stained. Some nuclear changes were noted and occasional cells

destroyed. Nissl described a granular degeneration of the neurones

with a prominence of the "unstainable" substance, together with a

swelling and crumbling of the cell bodies. Alzheimer often found free

nuclei near the apical processes. In the glia cells and vessel walls

granular detritus was observed. Acute and chronic cell alterations

are more common in old alcoholics. Pachymeningitis hemorrhagica is

sometimes found. Kraepelin considers it very doubtful whether wine or

beer drinking ever causes delirium tremens, whisky and gin being the

etiological factors as a general rule.

Korsakow's psychosis was first described in 1887. This is characterized

by a loss of memory, and falsification, with a marked tendency

to disorientation, and is often due to chronic alcoholism. It is

practically always accompanied by polyneuritic symptoms. According

to Bonhöffer, it usually follows delirium tremens. This occurred in

one-fourth of Kraepelin's cases. Occasionally it begins suddenly, but

as a rule gradually, during the course of a chronic alcoholism. The

patients frequently complain of dizziness, headaches and fainting

spells. In the foreground of this affection is the impairment of

memory. This is one of the characteristic features. The events of a

few hours ago are completely forgotten. Disorientation appears next.

This affects time more than anything else. The power of apprehension

or perception is very markedly impaired (one-sixth of the normal in

Kraepelin's cases) and the reaction time is greatly increased. He

also found memory reduced to one-third or one-fourth of the normal on

actual tests (repetition of words and syllables). Falsification of past

events is also demonstrable. This often leads to elaborate delusion

formations. The mood is usually anxious at first, later indifferent,

dull, suspicious, irritable, in some eases cheerful and even humorous.

The methods of life are completely changed. The patients neglect

themselves, lie in bed, etc. The physical signs are those of neuritis.

Muscular pains in the limbs appear, with evidences of loss of power.

Paraplegias and weakness of the grip are found. Romberg's sign is

frequently present. Anesthesias, hyperesthesias or paresthesias are

noted. The reflexes are usually decreased, rarely increased. Ataxia and

other difficulties of gait are common. The pulse is usually slower as a

result of involvement of the vagus. Speech difficulty, writing defects,

facial paralyses, weakness of the eye muscles, with inequality and

inactivity of the pupils, are to be expected. There are usually tremors

of the fingers. Epileptiform convulsions are not infrequent. Aphasia,

agraphia, apraxia, monoplegia, hemiplegic, etc., are observed in many

cases. Physical disturbances of various kinds due to chronic alcoholism

are also present.

At autopsy acute and grave alterations are found in the cells of the

second and third layers of the cortex. A granular degeneration (Körnig

Zellerkrankung) of the cells is also referred to by Nissl. There is

some fibre loss in the central convolutions and the internal capsule,

as well as in the columns of Goll. Hemorrhages and thromboses are to

be found. Alzheimer found encephalitic foci with proliferation of the

cells of the vessel walls sending out fibroblasts in the neighborhood,

and a destruction of the nerve fibres. These foci are found in the

central gray matter of the third ventricle, roof of the aqueduct,

etc. There is a formation of new vessels and an outwandering of cells

often accompanied by numerous hemorrhages into the gray matter around

the aqueduct of Sylvius. Wernieke has described this process as an

"acute hemorrhagic polioencephalitis superior" and finds it very

commonly associated with Korsakow's psychosis. It occurs, however, in

other chronic alcoholic conditions. The peripheral nerves also show a

polyneuritis. Bonhöffer found Korsakow's psychosis in three per cent

of his delirious cases. Thirty-three per cent of Kraepelin's cases

were women and only 24.5 per cent were under forty years of age.

Chotzen found Korsakow's psychosis in three per cent of his male and in

twenty-one per cent of his female alcoholics.

The acute alcoholic hallucinoses as described by Kraepelin are

characterized by well defined delusions of persecution and above all by

hallucinations of hearing, with a clear sensorium. In eighty per cent

of the cases the symptoms appear suddenly. Sometimes there is first an

abortive delirious attack. Usually a multiplicity of hallucinations of

hearing develop early. The patient hears threats and abusive language,

always directed against himself. Visual hallucinations also occur,

particularly at night. The other sensory fields are often involved.

At the same time well marked delusions manifest themselves. These

suggest every possible variety of persecution. Ideas of grandeur

are sometimes observed. All of these symptoms are worse at night

as a rule. Consciousness is usually fairly clear, and there is no

disorientation. There is often a mixture of anxiety and humor. Some

cases, however, are irritable and suspicious. Occasionally suicidal

tendencies appear. Conduct is usually not greatly disturbed and the

patient continues with his regular occupation. There is considerable

insomnia and a tendency to run around a great deal and act foolishly

at times. Physically, evidences of chronic alcoholism are always to be

found. The customary duration of these acute conditions is from three

to eight weeks, although they sometimes last for months. In a quarter

of Kraepelin's cases the termination was in deterioration. There is a

strong tendency to recurrence. The unrecovered cases are suspicious,

surly, quarrelsome and have hallucinations of hearing. This condition

may last for years. There are always occasional persecutory ideas.

One-fifth of Kraepelin's cases became chronic. Bonhöffer described a

paranoid type of long duration. The hallucinoses appear usually earlier

in life than Korsakow's psychosis but later than delirium tremens. In

Kraepelin's experience delirium tremens is three times as common as are

hallucinoses. He looks upon these two conditions, however, as different

clinical manifestations of "one and the same" disease process.

Alcoholic paralysis, so called, is a mixture of chronic alcoholic

symptoms with those of general paresis. There is a mental deterioration

with ideas of grandeur, emotional dulness, hallucinations, delusions

of jealousy, speech defect, tremors and polyneuritis. Epileptiform

attacks are frequent. Most of these forms according to Kraepelin

belong to Korsakow's psychosis or polioencephalitis hemorrhagica

superior. Alcoholic conditions may also be complicated by syphilis or

arteriosclerosis.

Since the alcoholic psychoses have been generally recognized as

such, there has been comparatively little difference of opinion as to

their differentiation. The classification of the American Psychiatric

Association is as follows:—

"The diagnosis of alcoholic psychosis should be restricted to those

mental disorders arising, with few exceptions, in connection with

_chronic_ drinking and presenting fairly well defined symptom-pictures.

One must guard against making the alcoholic group too inclusive.

Overindulgence in alcohol is often found to be merely a symptom

of another psychosis, or at any rate may be incidental to another

psychosis, such as general paralysis, manic-depressive insanity,

dementia praecox, epilepsy, etc. The cases to be regarded as alcoholic

psychoses which do not result from chronic drinking are the episodic

attacks in some psychopathic personalities, the dipsomanias (the true

periodic drinkers) and pathological intoxication, any of which may

develop as the result of a single imbibition or a relatively short

spree.

"The following alcoholic reactions usually present symptoms distinctive

enough to allow of clinical differentiation:

"(a) Pathological intoxication: An unusual or abnormal immediate

reaction to taking a large or small amount of alcohol. Essentially an

acute mental disturbance of short duration characterized usually by

an excitement or furor with confusion and hallucinations, followed by

amnesia.

"(b) Delirium tremens: An hallucinatory delirium with marked general

tremor and toxic symptoms.

"(c) Korsakow's psychosis: This occurs with or without polyneuritis.

The delirious type is not readily differentiated in the early stages

from severe delirium tremens but is more protracted. The non-delirious

type presents a characteristic retention defect with disorientation,

fabrication, suggestibility and tendency to misidentify persons.

Hallucinations are frequent after the acute phase.

"(d) Acute hallucinosis: This is chiefly an auditory hallucinosis of

rapid development with clearness of the sensorium, marked fears, and a

more or less systematized persecutory trend.

"(e) Chronic hallucinosis: This is an infrequent type which may be

regarded as the persistence of the symptoms of the acute hallucinosis

without change in the character of the symptoms except perhaps

a gradual lessening of the emotional reaction accompanying the

hallucinations.

"(f) Acute paranoid type: Suspicions, misinterpretations, and

persecutory ideas, often a jealous trend, hallucinations usually

subordinate; clearing up on withdrawal of alcohol.

"(g) Chronic paranoid type: Persistence of symptoms of the acute

paranoid type with fixed delusions of persecution or jealousy usually

not influenced by withdrawal of alcohol; difficult to differentiate

from non-alcoholic paranoid states or dementia praecox.

"(h) Alcoholic deterioration: A slowly developing ethical, volitional

and emotional change in the habitual drinker; apparently relatively few

cases are committed, as the mental symptoms are not usually looked upon

as sufficient to justify the diagnosis of a definite psychosis. The

chief symptoms are ill humor and irascibility or a jovial, careless,

flippant, facetious mood; abusiveness to family, unreliability and

tendency to prevarication; in some cases definite suspicions and

jealousy; there is a general lessening of efficiency and capacity

for physical and mental work; memory not seriously impaired. To be

excluded are residual defects due to Korsakow's psychosis, or mental

deterioration due to arteriosclerosis or to traumatic lesions.

"(i) Other types, acute or chronic (to be specified)."

Shadwell[222] states that in twenty-six Italian asylums 18.6 per cent

of their cases were directly or indirectly the result of alcoholism.

Twenty-one and one-tenth per cent of the males and 4.37 per cent of

the females admitted to the institutions of Switzerland from 1901 to

1904 were alcoholics. Twenty-one and thirty-seven hundredths per cent

of the admissions to the hospitals in Denmark between 1899 and 1903

were suffering from alcoholic psychoses. He gives the admission rate

in Austria as fourteen per cent and in France, 12.5 per cent. Clouston

some years ago estimated the admission rate in Great Britain and

Ireland to be about twenty per cent.

Pollock[223] has made a most interesting study of 1,739 cases of

alcoholic psychoses, the total number admitted to the New York state

hospitals between October 1, 1909, and September 30, 1912. Seventy-six

and five-tenths per cent of these were men, and 23.5 per cent, women.

The different conditions represented were as follows: Pathological

intoxication, .7 per cent; alcoholic deterioration, 7.7 per cent;

delirium tremens, 4.7 per cent; Korsakow's psychosis, 18.8 per cent;

acute hallucinosis, 36.7 per cent; chronic hallucinosis, 2.2 per cent;

paranoid states, 13.7 per cent; and all other forms, 15.5 per cent.

Among the males, acute hallucinosis predominated, while Korsakow's

psychosis constituted the largest percentage in the female patients.

Of the ascertained cases, .4 per cent showed a defective make-up, 10.3

per cent were inferior and 89.3 per cent were reported as normal. In

seventy-four per cent of the cases there was no history of insane

heredity. The father of the patient was insane in 3.7 per cent of the

series and the mother in four per cent; 25.8 per cent in all had a

history of insane heredity. Thirty and five-tenths per cent of the

male and thirty-seven per cent of the female patients had alcoholic

fathers and three per cent of the men and 8.8 per cent of the women

had alcoholic mothers. Pollock found the percentage of intemperate

fathers twice as high in the alcoholic psychoses as in the patients

suffering from other conditions. In 94.1 per cent of the cases there

was no family history of nervous diseases. Eighty-one and one-tenth per

cent of the men and 93.4 per cent of the women came from cities. Of the

male patients 26.8 per cent were unskilled laborers; 16.1 per cent of

the women were seamstresses, and 11.7 per cent, the wives of laborers.

The alcoholic cases constituted fifteen per cent of the male, five per

cent of the female, and ten per cent of the total first rate admissions

during the three years in question. The rate of alcoholic psychoses was

over twice in as great in the foreign born population as in the native.

Three thousand four hundred and sixty-two cases diagnosed as alcoholic

psychoses were admitted to the New York state hospitals during a

period of eight years (1912 to 1919 inclusive). Of these, pathological

intoxication constituted 2.91 per cent, delirium tremens, 5.97 per

cent, Korsakow's psychosis, 20.94 per cent, acute hallucinosis, 37.31

per cent, chronic hallucinosis, 3.66 per cent, acute paranoid states,

5.01 per cent, chronic paranoid states, 3.78 per cent, and alcoholic

deterioration, 8.34 per cent. The remainder represented miscellaneous

types variously described. These figures, of course, relate largely

to a time when there were no restrictions on the sale of alcoholic

beverages. During 1918 and 1919 the admission rate for alcoholic

psychoses in New York was only 4.58 per cent. In Massachusetts in 1919

it was 7.47 per cent, and in twenty-one other hospitals in various

states it was 5.04 per cent. A study of 34,935 first admissions to

forty-eight hospitals in sixteen different states during 1917, 1918 and

1919 showed the alcoholic psychoses to represent 5.07 per cent of the

total number. With the advent of prohibition the alcoholic psychoses

as far as this country is concerned have become a matter of little more

than historical interest. The admission rate in the New York state

hospitals for 1920 was only 1.9 per cent.

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