CHAPTER VIII.

THE EXAMINATION OF THE THORAX.

I. METHODS OF EXAMINATION.

1. =Thoracic Cavity.= As soon as the sternum is removed the =anterior

mediastinum= and the =pleural cavities= are examined, noting first

the =position= and =relation= of the =thoracic organs=, quantity and

character of mediastinal fat, the contents of the pleural cavities,

pleuritic adhesions, etc. Pleuritic exudates should be removed before

they have become mixed with blood from the cut vessels or heart; and

the pleural surfaces should be examined before their appearance has

been changed by exposure to the air or to fluids. Pleuritic adhesions

should be broken or cut, beginning with the left side and then on the

right, and the entire surface of both lungs wholly freed.

2. =Thymus.= The thymus is then examined by means of transverse cuts;

or, when large, is dissected from below upward, turned up onto the

neck, and removed later in connection with the neck organs. When

no traces of thymic tissue are visible to the naked eye the thymic

fat should always be cut transversely and examined for the presence

of small lymphoid nodules. In the case of hypertrophic thymus

the question of pressure upon the trachea becomes of very great

importance, and, to settle this, the trachea should be opened above

the sternum before the thymus is removed; or the thymus may be taken

out in connection with the trachea and both sectioned horizontally

at the same time. In cases of sudden death, in which the thymus may

be an etiologic factor, it is safest to examine the trachea from

above the sternum before the thorax is opened, or to fix the whole

body (infant’s or child’s) in formalin and then to remove thymus with

trachea, and examine by means of transverse sections.

The heart is examined before the lungs chiefly for two reasons:

Its blood-content can be more accurately determined, and the blood

caught in the pericardial sac, so that when the pulmonary vessels

are cut in the removal of the lungs there is no gush of blood into

the pleural cavity.

3. =Pericardial Sac.= This is next examined with respect to the

degree of intrapericardial tension. Its anterior wall is then picked

up at about its middle by the thumb and index finger of left hand,

and the point of the long section-knife, with cutting edge outward,

is pushed through the pericardium and a small slit made into the sac.

The escape of gas or air should be noted at this time. A sterile

pipette may now be introduced and the fluid contents of the sac

secured for bacteriologic examination; or before the pericardial sac

is opened the pericardium may be seared with a hot iron and a sterile

pipette pushed through it into the cavity. The longitudinal incision

through the pericardium is now extended upward to its attachment to

the great vessels, and through the opening thus made the character

and amount of the pericardial fluid are determined. The incision is

then extended to the left at its lower end by cutting the sac-wall

toward the apex of the heart. Through the three-cornered incision

thus made the heart is lifted out of the sac and the surfaces of the

parietal and visceral layers of the pericardium examined. Localized

adhesions of the pericardium may be cut or torn, extensive or

complete adhesions may be separated when this is possible; if this

cannot be done, the pericardial layers are cut with the heart wall.

4. =Section of the Heart.= The heart may be examined either in the

body or outside. The choice of several methods may be taken, and

the one most convenient and easy of performance is advised, rather

than a method based upon such considerations as the direction of

the blood-current in the normal body. The chief essential is to

expose completely the interior of the heart with the least possible

disturbance of anatomic relationships, and to accomplish this in

the simplest and easiest way. Such a method must leave the heart

in such shape that it can be reconstructed for histologic study or

utilized as a museum specimen. This can be accomplished by a modified

_Rokitansky_ method, as follows:

The heart is first carefully inspected as it lies in the pericardial

sac. The apex is then lifted in the left hand and the posterior wall

inspected. The heart is then drawn up over the right edge of the

ribs, so that the left border of the heart presents uppermost as

the line of greatest convexity. The point of the narrow brain-knife

(amputation-knife), with cutting edge upward, is then inserted

through the wall of the left ventricle at the apex, just to the left

of the septum, and the knife pushed into the cavity until the point

can be forced through the ventricular wall just below (ventricular

side) the left auriculoventricular ring, and the ventricle-wall is

then cut upward (as the heart is held) to the apex, in the line of

greatest convexity, exposing the cavity of the left ventricle. The

knife is laid aside and the ventricle is explored with the fingers

of the right hand and the size of the mitral opening estimated.

Before the fingers are introduced through the valvular openings

the flaps should be carefully examined to see that no vegetations,

thrombi, etc., are in danger of being loosened by them. With the

opening of the heart-chambers the blood, if fluid, may pour out into

the pericardial sac and flood the pleural cavity if not prevented

by sponging or by removing it by means of a beaker. The knife is

then introduced on the flat through the mitral opening into the left

auricle in a line continuing the first incision with the junction of

the left pulmonary veins. (See Fig. 38.) The knife is then turned

with cutting-edge upward, the point thrust through the upper left

pulmonary vein or between the left pulmonary veins, and the auricular

wall is cut upward (downward anatomically) to meet the first incision

below the mitral ring. The incision should pass between the mitral

segments. The left auricle, mitral ring and flaps and the greater

portion of the left ventricle are thus exposed and should be

inspected.

[Illustration: FIG. 38.—Section of left ventricle and auricle, when

heart is examined in the body. (After Nauwerck.)]

The heart is then taken in the left hand and held by the anterior

flap of the left ventricle, with the fingers inside the ventricle

and the thumb on the outer surface of the anterior wall of the left

ventricle, and lifted up vertically out of the pericardium. The

brain-knife held perpendicularly, with cutting-edge to the right, is

pushed through the right ventricular wall just to the right of the

septum, carried across the cavity of the ventricle, to engage again

in the ventricular wall in the line of greatest convexity, just below

(anatomically) the right auriculoventricular ring, and the wall is

then cut upward to the apex. The right ventricular cavity is thus

opened, the fingers are introduced to explore the tricuspid ring, and

the cavity and contents are inspected. The knife, held flat, is then

carefully introduced through the tricuspid opening into the right

auricle, the cutting edge outward, and its point thrust through the

wall of the auricle midway between the superior and inferior venæ

cavæ, and the auricular wall and tricuspid ring are cut upward toward

the apex to meet the first incision into the right ventricle. If

sufficient care is taken the incision will fall between the anterior

and posterior cusps. Right auricle, tricuspid flaps and ring, and the

right ventricle are thus exposed for inspection.

The heart is then drawn downward and allowed to lie flat in the

pericardial sac, and the pulmonary artery is then explored with the

fingers of the right hand. While the anterior wall of the right

ventricle is held by the thumb and index-finger of the left hand the

knife is then introduced, on the flat, along the right side of the

septum, into the pulmonary artery; the edge is turned upward and the

point pushed through the wall of the artery, about 3 cm. beyond the

ring, and a cut made toward the apex through the anterior wall of the

artery, pulmonary ring and anterior wall of right ventricle, just

to the right of the septum. The pulmonary artery, ring, pulmonary

flaps, and right side of auricular and ventricular septum are now

inspected. In cutting the pulmonary ring care should be taken to make

the incision between the two anterior cusps.

With the heart still lying flat in the pericardial sac, the aortic

opening is explored by the index-finger of the right hand and the

size of the ring estimated. The knife is then introduced on the flat,

into the left ventricle, along the left side of the septum, through

the aortic opening and as far as possible into the aorta. It is then

turned, with the cutting edge upward, and the point pushed through

the anterior wall of the aorta. The heart is then drawn downward and

slightly raised by the left hand, holding it at the apex by the two

flaps of the right ventricle. The knife is then drawn from above

downward toward the apex, cutting in succession the anterior wall of

the aorta, across the pulmonary artery, through the aortic ring, and

the anterior wall of the left ventricle, just to the left side of

the septum. By dissecting away the pulmonary artery from the aorta

the incision through the former may be avoided. (See Fig. 41.) When

desired this cut may be brought down through the septum instead, but

if the bundle of His is to be studied in serial sections the cutting

of the septum should be avoided. The enterotome or long straight

shears may be used for all the incisions except the first ones made

into the ventricles. For these the knife is necessary. The incision

through the aortic ring usually cuts the anterior segment, but by

making the cut more to the right the incision will pass between the

anterior and the right posterior flaps.

Before the valvular orifices are cut it is often expedient to test

the adequacy of the valves by means of water or air. The hydrostatic

test is employed to the best advantage in the case of the pulmonary

and aortic valves, either by pouring water into the vessels, or by

immersing the heart in water and then lifting it up quickly. In the

case of the auriculoventricular valves the air-test is carried out

by inserting the nozzle of a bellows through an opening made in

the ventricular wall and noting the effect of blowing and suction.

Graduated cones or balls may be used for more accurate measurement of

the orifices, or they may be measured after they have been cut.

If sufficient care is exercised in cutting the valvular rings

the incision can be carried between the flaps without injury to

the latter. This is often desirable in cases of valvular lesion,

endocarditis, etc. In such cases the valvular rings may be left

uncut, the line of incision being broken by the auriculoventricular

ring, when the mitral and tricuspid valves are concerned. The

pulmonary and aortic rings may also be left uncut; the incisions are

stopped at the rings, and then begun again in the vessel-walls beyond

the valves.

When bacteriologic examinations of the heart-contents are to be made

the wall of the auricles or right ventricles can be seared with a

cautery and a pipette introduced through the seared area; or the

heart can be opened with a sterile knife, care being taken not to

introduce the fingers into the opening or to permit the entrance of

water.

Excellent preparations for the museum or for demonstration purposes

can be made by distending the heart with alcohol or formalin. Blood

and blood-clots should first be washed out. When fixed the heart may

be sectioned in various planes, leaving the segments attached by the

epicardium posteriorly, or openings may be cut in the walls. A very

good picture of hypertrophy and dilatation is obtained by making a

transverse cut through the ventricles midway between apex and base.

Alterations in the form and position of the ventricular septum are

best seen by this method.

After the opening of the heart and the inspection of the orifices,

valves and auricular and ventricular septa, the coronary vessels

should be examined by transverse cuts, or opened by fine

probe-pointed scissors, beginning at their origin in the aorta. The

auricular septum should be carefully examined for possible defects.

While this is being done the wall should not be put on the stretch,

but should be lax. The auricular appendages should be cut open from

the auricles and examined for thrombi, which are of not infrequent

occurrence in them. The mouths of the coronary veins and the veins

of Thebesius should be examined also. The cardiac muscle is examined

by parallel, vertical or horizontal incisions. The papillary muscles

should be cut longitudinally from apex to base. The cardiac plexus

and the ganglion of Wrisberg should be examined before the heart is

removed.

When the heart is in a state of rigor mortis the contraction should

be made to pass away by kneading or by the application of heat,

before the organ is opened, or before any measurements are taken.

After the heart has been opened it may be removed for weighing.

The heart may be removed first and then opened outside of the

body. The organ is grasped in the left hand and lifted vertically

and upward toward the head as far as possible, putting all of the

attachments on the stretch. The vessels are then cut from below

upward, first the inferior vena cava, then the pulmonary veins, the

superior vena cava, pulmonary artery and lastly the aorta. (See

Fig. 39.) The vessels should be cut as closely as possible to their

exits through the pericardium, and care must be taken to get out the

auricles entire.

[Illustration: FIG. 39.—Removal of Heart. Dark line shows incision

through vessels. (After Nauwerck.)]

After removal from the body the heart is placed upon the board with

its anterior surface up, and the apex toward the operator. It may

then be opened by the same method given above, by inserting the

point of the brain-knife into the left ventricle just to the left of

the septum, and cutting first the wall of the left ventricle along

its left border as far as the mitral ring, exploring the mitral

orifice, and then cutting it and the auricular wall into the upper

left pulmonary vein with the long shears. The right ventricle,

right auricle, pulmonary artery and finally the aorta are opened

in succession, using the enterotome for all cuts except the first

opening of the ventricle. The first incisions into the ventricles

can be made very conveniently by holding the heart vertically with

apex up, and the ventricle to be opened toward the prosector. The

brain-knife is held vertically and its point inserted into the

ventricle, just to the right or left of the septum, according to the

ventricle to be opened, then carried across the cavity and pushed

through the ventricular wall below the auriculoventricular ring, and

the wall is then cut toward the apex. The remaining incisions are

most easily made with the enterotome when the heart is held flat on

the board with its anterior surface up. When the heart is opened

outside of the body the Virchow method of opening in the direction

of the blood-stream may also be used. (See below.)

Under certain conditions other methods must be employed for the

examination of the heart. In cases of suspected aneurism, pulmonary

embolism, patent ductus arteriosus, etc., the thoracic organs should

be removed _en masse_ and dissected on the table. They may be removed

in connection with the neck-organs or alone. In the latter case the

trachea is cut transversely above the sternum, the fingers of the

left hand introduced into the trachea, and, while traction downward

is being made with force, the œsophagus and cervical vessels are cut

transversely, the trachea and vessels stripped down to the level

of the clavicle, and the subclavian vessels cut on both sides. The

thoracic organs are then stripped from the vertebræ down to the

diaphragm and cut off just above the latter.

The pulmonary artery may be examined _in situ_ before the heart is

opened by thrusting a sharp-pointed scalpel through the wall of the

artery just beyond the valves and cutting upward to the branches

going to the right and left lungs. This incision may be extended

downward through the pulmonary valve and the anterior wall of the

right ventricle, and the right side of the heart first exposed.

=Virchow Method.= The heart is rotated toward the left side

of the cadaver so as to bring the venæ cavæ into view, and is

held by the index-finger and thumb of left hand. An incision is

then made in the wall of the right auricle, beginning midway

between the two cavæ and extending downward as far as the right

auriculoventricular ring, in the direction of the right ventricular

ridge. The tricuspid is examined from above. The tricuspid ring

may be left uncut and an incision made in the ventricle-wall,

beginning just below the valve and extending downward along the

right ventricular ridge to the septum, or the incision may be

carried down in the same line passing through the tricuspid ring.

The long narrow-bladed knife or the enterotome is introduced into

the right ventricle and an incision made from the middle of the

first incision, just above the insertion of the anterior papillary

muscle, through the pulmonary orifice into the pulmonary artery,

passing between the two anterior leaflets of the pulmonary valve.

The heart is now drawn up on the right edge of the ribs so that

the left ventricular border presents uppermost. The left auricle

is then opened by an incision beginning in, or just below, the

lowermost pulmonary vein and extended in the direction of the left

ventricular ridge as far as the auriculoventricular ring. Beginning

just below the ring an incision is made through the entire length

of the left ventricular ridge as far as the apex and to the septum,

which lies usually beyond the apex. A second incision is then made

in the left ventricle from the apex, extending through the anterior

ventricular wall close to the septum, parallel to the descending

branch of the anterior coronary artery and about 1 cm. from it,

and passing through the aortic opening between the anterior and

the right posterior cusps. This is the more easily accomplished

if the pulmonary artery has been dissected away from the aorta, so

that the incision can be carried well over to the right. (See Fig.

41.) As the chambers of the heart are opened the contents should

be inspected, clots removed, and the valvular orifices examined

from the upper side. The coronary arteries are then opened with the

fine probe-pointed scissors. When the heart has been removed from

the body it may be opened on the board by following the method as

given above. The heart is held very conveniently for the Virchow

incisions by putting the four fingers of the left hand beneath it

and the thumb on the anterior surface; complete pronation puts

the heart in the position for opening the right side; complete

supination gives the position for opening the left side.

[Illustration: FIG. 40.—Section of right auricle and ventricle,

according to Nauwerck.]

[Illustration: FIG. 41.—Incision for opening of aortic ring; same

for all methods described in text. (After Nauwerck.)]

=Nauwerck Method.= By this method the left auricle, left ventricle,

right auricle and right ventricle are opened in succession. The

heart is seized in the left hand, and without rotation is drawn

upon the right edge of the ribs. Beginning in the upper left

pulmonary vein or between the veins an incision is made through

the wall of the auricle to the sulcus circularis, avoiding any

injury to the coronary vessels. Beginning below the mitral ring

an incision is carried along the left ventricular ridge to the

apex. The left auricle and ventricle are then cleared of blood

and the mitral opening examined. The heart is then put back into

its natural position; the left thumb is placed in the apex of the

left ventricle and the four fingers passed over the right border

of the heart to its posterior surface, rotating the heart to the

left until the right auricle is brought uppermost. (See Fig. 40.)

Then an incision is made through the wall of the right auricle,

beginning midway between the superior and inferior venæ cavæ and

extending to the tricuspid ring, then begun again 1 cm. below, is

carried along the right border of the heart, or slightly anterior

to it, as far as the septum. (See Fig. 40.) The contents of right

auricle and ventricle and the tricuspid valves are now inspected.

The heart is then removed from the body by lifting it up vertically

as far as possible and cutting the vessels from below upward as

close as possible to their exits through the pericardial sac. The

hydrostatic test is then applied to the aortic and pulmonary valves

by pouring water into these vessels, or by immersing the heart an

water and then lifting it out. The heart is then laid flat on the

board with apex toward the operator. The enterotome is introduced

into the right ventricle and through the pulmonary orifice and an

incision made through the anterior wall of the right ventricle,

beginning just above the anterior papillary muscle at about the

middle height of the ventricle, and cutting through the pulmonary

conus and pulmonary valve well to the left, close to the septum,

following the narrow ridge of fat at the base of the artery so as

to pass between the left anterior and posterior segments. The heart

is then rotated on its vertical axis so that the right auricle is

turned toward the prosector, and the tricuspid ring is opened with

the intestinal shears. The auricular appendage is then cut open

from the auricular incision. The heart is then held in its former

position and an incision is made in the anterior wall of the left

ventricle just to the left of the septum, from the apex through the

aortic ring and the left wall of the aorta, while the pulmonary

artery is pulled to the right. (See Fig. 41.) Care must be taken

not to damage the right border of the base of the mitral; the cut

should pass half way between the pulmonary orifice and the left

auricular appendage, cutting the left aortic flap. If it is desired

to save the cusps the pulmonary artery may be dissected from the

aorta and the incision carried between the right posterior and the

anterior valve-flaps. The heart is again rotated toward the right

and the mitral ring is cut with the enterotome, which is introduced

from the left auricle into the left ventricle. The left auricular

appendage is then cut open. The heart-wall is then examined by

means of parallel vertical or horizontal incisions. The papillary

muscles are cut longitudinally from apex to base. The coronary

vessels and their branches are then examined, partly from the aorta

and partly from the incisions through the muscle.

=Prausnitz Method.= The heart is removed and held in the palm of

the left hand and two vertical incisions are made on either side

of the septum, parallel with it, and extending from base to apex.

Two other incisions are then made from base to apex on the outer

borders of the ventricles, connecting at the apex with the first

incisions. The ventricles are opened by the triangular flaps of

the anterior wall thus formed, these flaps being attached at the

base of the heart. The contents of the cavities are examined and

removed; the valvular orifices and flaps are examined, and the

pulmonary and aortic rings are cut through with the shears by

extending the two incisions made on each side of the septum, taking

care to pass between the cusps.

The heart can also be opened with the long shears alone. The

openings of the two cavæ in the right auricle are connected by

an incision. The auricular appendage is opened by a second cut.

The shears are then put through the tricuspid ring, and this with

the right ventricle is cut, the incision following the right

ventricular border. The pulmonary orifice is then opened by a cut

made along the right side of the septum. The left heart is opened

through the pulmonary veins, cutting first the auricle-wall, then

the mitral ring and ventricular wall to the apex. An incision is

then made along the left side of the septum, through the aortic

orifice into the aorta.

5. =Section of the Lungs.= The general inspection of the pleural

cavities and pleural surfaces is made as soon as the thoracic cavity

is opened, as indicated above. If a pneumothorax is present the

pleural cavity on the affected side is filled with water, the neck

organs are exposed and a tube inserted into the trachea. When air

is forced through this bubbles will escape from the perforation

and the opening can be easily located. When extensive or complete

pleural adhesions are present, so that they cannot be separated, it

becomes necessary to remove the costal pleura in connection with

the visceral layer. This is accomplished by loosening the costal

pleura and subpleural fascia at the cut edge of the ribs with the

blade of the knife, until the fingers and, finally the hand, can be

worked in between the costal pleura and the chest-wall, gradually

separating the two until the entire lung is freed with both layers

of pleura adherent. Firm adhesions at the apex may have to be cut

with the knife. Similar adhesions with the pericardium or diaphragm

may make it necessary to cut out the adherent portion with scissors

or knife and remove it in connection with the lung. When the pleural

adhesions are very firm upon the right side the prosector may find

it most convenient to stand at the left side of the cadaver and

from this position separate the right costal pleura from the chest

wall. An assistant may be of great service in pulling the thoracic

wall outward. The edge of the ribs or cartilages may be covered

with a towel or the skin may be drawn over it to protect the hands.

In extreme cases it may be necessary to saw the ribs and remove

them in connection with the lungs. Sometimes the adhesions may be

separated more easily if the neck-organs are first removed down to

the clavicle, and then, in connection with the lungs, are removed _en

masse_, by means of powerful tugs, from above downward. The apical

and posterior adhesions may be torn fairly easily in this way when

ordinary manipulations in the thoracic cavity have no effect upon

them.

When the pleural surfaces are free the =left lung= is lifted out

of the cavity onto the right edge of the chest-wall, pulling it

forcibly over to the right so that its posterior surface becomes

uppermost. In this position the lung may be sectioned by one or more

main incisions made with the long section-knife, cutting the organ

from apex to base, down upon the ribs in the direction of the main

bronchi and vessels. After the examination of the cut surfaces the

organ may be returned to the cavity. It is better, however, to remove

the lung, and section it outside the body. This is done by cutting

the mediastinal pleura, pulmonary vessels and main bronchus with the

cartilage-knife, while the lung is held upon the right edge of the

thoracic opening, holding the knife so that its blade strikes the

edge of the costal cartilages.

[Illustration: FIG. 42.—Section of left lung. (After Nauwerck.)]

The lung, when free, is placed upon the board with its hilus downward

and base toward the prosector. (See Fig. 42.) It is then held in the

left hand, as shown in the illustration, the thumb holding the lower

lobe, the index-finger between the lobes with its tip upon the main

bronchus, the other fingers holding the upper lobe. With the long

section-knife held slightly obliquely toward the anterior edge the

main-incision is now made in one sweeping cut from apex to base,

along the line of greatest convexity, down upon the main-bronchus

and its chief branches and the large vessels. Care should be taken

not to cut off the bronchi of the two lobes from the main bronchus.

Incisions parallel to the main one may be made, if desired. Usually

it suffices to go carefully over the remaining part of the lung,

feeling it carefully for airless solid areas; if such are present

they may be sectioned separately. The =bronchi= are then opened from

the cut surface by means of the probe-pointed scissors, cutting as

near to the pleura as possible. The sound or director may be used

with advantage in opening up cavities from the bronchi. The position

of the lung should be so changed that the bronchi always extend

away from the prosector in a straight line. The portion of the lung

containing the uncut bronchus should be left hanging over the left

hand to put it on the stretch, thereby facilitating greatly the

opening of the bronchus. The =pulmonary vessels= are opened with

fine probe-pointed scissors from the cut surface. The bronchial

lymphglands are then sectioned with the knife.

[Illustration: FIG. 43.—Section of right lung. (After Nauwerck.)]

The =right lung= is then lifted up out of the thorax onto the

right side of the thoracic opening, and is either sectioned in

this position, or the mediastinal pleura, pulmonary vessels and

bronchus are cut from below upward with the knife, its edge being

directed against the ribs. When freed the lung is placed on the

board, root downward and apex toward the prosector. (See Fig.

43.) The index-finger is put between the upper and lower lobes,

the thumb holds the upper lobe, the other fingers are spread out

over the surface of the lower lobe. The main-incision is then made

in a sweeping cut, from base to apex, along the line of greatest

convexity, the knife-blade being held slightly obliquely toward the

anterior border (see Fig. 43), cutting down upon the main bronchus

and its first division. Other parallel cuts may be made. The middle

lobe is then sectioned by a sagittal incision on its anterior

surface, directed toward its anterior border. The =bronchi, pulmonary

vessels= and =bronchial lymphnodes= are then opened as in the case of

the left lung.

Bacteriologic examinations may be made from smears or cultures made

from the cut surfaces; or, to avoid contamination, the surface

may be seared with a hot iron and the material obtained by means

of a sterile pipette pushed through the seared surface into the

lung-tissue.

The lungs may also be removed by drawing them downward and outward,

away from the root, while the bronchi and pulmonary vessels are

cut, the knife being directed against the vertebræ, care being

taken to avoid cutting the aorta and œsophagus. The lungs are then

lifted up toward the middle line, while the mediastinal pleuræ are

cut. The section of the lungs may be carried out, if so desired,

from the root, the main bronchus and then all of the branches as

far as the pleuræ being opened up by means of the probe-pointed

scissors. Other incisions may be made if desired.

As mentioned above, it is sometimes more convenient to remove the

thoracic organs _en masse_, either alone, or in association with

the neck organs. When this is done the dissection follows the

method of Letulle (see above), or the organs may be separated and

sectioned according to the methods just given.

The section of the heart usually precedes that of the lungs, in

order that the blood-content of the former may be more correctly

estimated. Under certain conditions it may be more convenient or

expedient to section the lungs first, beginning with the left one.

When the neck-organs are not removed the section of the thorax closes

with the examination of the =aorta, oesophagus=, =thoracic duct= and

=thoracic vertebrae=. The blood-vessels and œsophagus are opened

with the curved scissors, from above downward, the contents noted,

and the walls examined. The thoracic duct is best dissected out

from the right side, by cutting along the right side of the aorta

and turning the latter over to the left. The duct is more easily

recognized at its lower end. It may be inflated with the blow-pipe,

or opened with a probe and fine probe-pointed scissors. Sometimes

the duct can be most easily found by removing the left lung and

then turning the right lung over into the left pleural cavity. The

posterior mediastinal tissues are put on a stretch, so that the duct

can be recognized through the pleura. For the examination of the left

subclavian vein the left clavicle should be removed.

II. POINTS TO BE NOTED IN THE EXAMINATION OF THE THORAX.

1. =Thoracic Cavity.= Presence of gas or air (pneumothorax,

infections with colon bacillus, gas-forming bacillus, proteus,

etc.), relative degree of pressure, odor, etc. Measure contents of

each pleural sac; note character of fluid (clear, turbid, bloody,

chyliform, chylous, purulent, fibrino-purulent). Normally the pleuræ

are moist-shining, smooth, grayish, transparent; only a few drops

of fluid found in the cavities. In cases of slowly progressive

cardiac insufficiency large amounts of clear fluid may collect in

the cavities just before death. Non-inflammatory collections of

fluid also occur in general œdema. In these conditions the pleuræ

are not cloudy or dull, while in the case of inflammation the

pleural surfaces are dry, cloudy, dull-shining, injected, rough

or covered with fibrinous or purulent exudate. Examine pleural

surfaces particularly for evidences of inflammation, recent and old

tuberculosis, primary and secondary neoplasms (carcinoma).

2. =Position of Thoracic Organs.= Locate anterior borders of lungs,

apex and borders of heart. The normal lung collapses after the

removal of the sternum. How much of the pericardial sac is left

uncovered by the lungs?

3. =Anterior Mediastinum.= Note character of connective-tissue,

amount and color of fat-tissue, number and size of lymphnodes,

occurrence of œdema or emphysema. An artificial œdema may be caused

by the injection of large quantities of salt solution in the pectoral

region just before death. An artificial emphysema may be produced by

the removal of the sternum. The condition of the large veins in the

upper portion of the mediastinum should be noted before the heart

is removed. Are they lax, moderately full, or distended? Secondary

tumors, hemorrhages, abscesses, œdema and emphysema are the most

common pathologic conditions.

4. =Thymus.= The writer believes that the weights usually given

for the thymus in the new-born are too high, and that 7-10 grms.

represents the usual normal weight. A gland weighing 20 grms. or

more must be regarded as enlarged. The organ reaches its fullest

development at the end of the second year. Atrophy begins then,

developing slowly up to the age of puberty, after that more rapidly.

In adults the thymus normally consists of a mass of adipose

tissue containing lymphoid nodules, in some of which corpuscles

of Hassall persist to old age. Postmortem softening should not

be mistaken for abscesses. The most important pathologic change

is hypertrophy. Pressure of the enlarged gland upon the trachea,

nerves or great vessels may cause thymic stridor, asthma, or thymic

death (“lymphatic constitution”). Enlargement of the thymus may

occur in “status lymphaticus,” exophthalmic goitre, cretinism,

myxœdema, Addison’s disease, acromegaly, myasthenia gravis, epilepsy,

scorbutus, rachitis, tonsillar hyperplasia, adenoids, congenital

syphilis, Hodgkin’s disease, leukæmia, anencephaly, anæmia, acute

infections, or it may exist as an independent affection. Oedema,

congestion, inflammation, tuberculosis, neoplasms, etc., may also

cause an enlargement. Absence of the thymus has been observed.

Primary and secondary forms of atrophy in association with marasmus

occur in children. Note relation of size of thymus to condition of

child; atrophy of the organ is usually coincident with marasmus.

Inflammation, tuberculosis, cysts, primary and secondary neoplasms,

gummata, etc., are not common.

5. =Pericardium.= Note tension of sac, fluctuation, adhesions,

thickness, character of inner surface, contents (amount, color, odor,

presence of fibrin, blood or pus, gas). Normally there are about 5-10

c. c. of clear yellow fluid in the sac. Both peri- and epicardium

normally are moist-shining, smooth, grayish and transparent. Large

amounts of clear watery fluid may collect in the pericardial

sac in slow death in cases of chronic valvular lesions, chronic

nephritis, bronchitis and emphysema, but the surface of the peri-

and epicardium remains smooth and shining. In inflammatory increase

of the pericardial fluid the serous surfaces are dull, cloudy or

dry, and may be covered with a layer of fibrin, the fluid is more

or less cloudy and contains flakes or strings of fibrin, or may be

purulent. The fibrinous exudate may be very extensive and from the

movement of the heart be drawn out into bands, threads or villus-like

prominences (cor hirsutum or villosum). Pericarditis is common in

acute rheumatism, septicæmia, pyæmia, puerperal fever, osteomyelitis,

pneumonia, and as a terminal infection in cardiac and renal

disease. Tuberculosis is one of the most common causes of purulent,

fibrinous and hemorrhagic pericarditis, particularly of the cor

villosum. Examine surfaces for tubercles. The presence of blood in

the pericardial exudate points usually to tuberculosis or malignant

neoplasm, but in small amount may be found in various infections

and intoxications. The age of the pericarditis may be judged by the

amount of organization of the exudate, adhesions, thickenings, etc.

“Milk spots,” “soldier’s spots,” “tendinous patches” or “friction

scleroses” represent hyaline thickenings of the pericardium due

to old pericarditis. Total synechia or atresia of the cavity may

occur. As the result of calcification of an old pericarditic exudate

the heart may be surrounded by a calcareous sheath (“stony heart,”

“petrified heart”). Hæmopericardium results from the rupture of the

heart, aorta, pulmonary artery or coronary vessel. Petechiæ of the

peri- and epicardium are found in pyæmia, septicæmia, hæmophilia,

scurvy, severe anæmia, leukæmia, chronic nephritis, and death from

suffocation and various intoxications. Pneumopericardium may be due

to perforating wounds, or to perforations from lungs, stomach or

œsophagus, or to infections with gas-forming bacilli. Malformations

are rare (diverticula, ectopia). Tuberculosis is usually secondary.

Gummata are rare. Actinomycosis is usually secondary to actinomycosis

of the neck or lungs. Primary neoplasms are rare. Secondary

carcinoma and sarcoma (especially lymphosarcoma) are more frequent.

Cysticercus, trichina and echinococcus are rare.

6. =Heart.= Note more carefully its position, whether displaced to

right or left, location of apex, borders, etc. Relative size compared

to cadaver’s right fist, which is usually a little smaller than the

heart. Weight and measurements:—(The heart should be weighed after it

has been opened, and its cavities freed from blood and clots.)

Average weight in adult male, about 300-350 grm.

Average weight in adult female, about 250 grm.

Normal limits, 200-350 grm.

Weight of heart to body-weight in adult male, 1:169; in the female,

1:162.

Circumference at base of ventricles 25.8 cm., length of ventricles

8-9 cm., breadth 8.5-10.5 cm., thickness 3-3.6 cm.; minimal

measurements are for the female. Auricles are 5-6 cm. in length.

Compare ventricles as to size.

Note form (long, cylindrical, pyramidal, broad, short, round, etc.)

In hypertrophy of the left ventricle the heart is longer and more

cylindrical; in hypertrophy of the right it is broader and more

rounded. Normally the apex is formed by the left ventricle, the

sulcus longitudinalis running to the apex and nearly dividing the

heart into halves. In hypertrophy of the right ventricle the apex

is formed by this ventricle, the sulcus longitudinalis passing to

the left of the apex; in hypertrophy of the left ventricle the

longitudinal sulcus runs to the right of the apex. What part of the

heart lies anteriorly? (Normally a large part of the right ventricle.)

The consistence of the organ, particularly that of the ventricles,

should be noted (firm, flabby, soft, etc.). Condition of the

heart-chambers (empty, contracted, dilated, full). Rigor mortis

should be removed by kneading or by the application of heat. The

amount of subepicardial fat, its color, translucency, occurrence

of serous atrophy, œdema, subepicardial hemorrhage, etc., are

to be noted. In marasmus a serous or mucoid degeneration of the

subepicardial fat is not uncommon. The subepicardial fat increases

with age, and is normally most abundant along the grooves and

blood-vessels, particularly the auriculoventricular grooves and

on the right ventricle. Normally the color of the heart-muscle

of the ventricles should be seen through the epicardium. The fat

is increased in obesity, chronic alcoholism, chronic anæmia,

tuberculosis, etc. When the fat-infiltration is so marked that

the muscle cannot be seen the condition is known as adipositas or

obesitas cordis, or in extreme cases as _lipoma cordis capsulare_.

7. =Right Heart.= Note amount of blood contained in right chambers

(over-distended in death from asphyxiation, pneumonia, etc.), also

its consistence (thick, thin, watery), color (light, dark, red,

yellowish, chocolate, purplish), blood-clots (size, color, cruor,

lardaceous clots, chicken-fat clots, pus-like clots, consistence,

moisture), presence of free fat, gas or air, diffusion of hæmoglobin,

presence of bile-pigment in blood. Note also amount and character

of blood in venæ cavæ. The size of auricular and ventricular

cavities should be estimated, noting condition of trabeculæ and

papillary muscles (atrophic, flattened, hypertrophic, fatty,

fibroid, calcification). The musculature of the ventricular walls

is examined as to its thickness (normally the right ventricle wall

is 4-5 mm. thick). Postmortem contraction should not be mistaken

for hypertrophy. The color of the heart-muscle normally is pinkish

in infants, flesh-red in adults, and brownish-red in old age and

in atrophy following compensatory hypertrophy (brown atrophy).

Under normal conditions the muscle is translucent. In cloudy

swelling the heart-muscle appears cloudy and opaque as if cooked.

Fatty degeneration appears as yellowish, opaque patches or streaks

(“tiger-heart”), particularly in the papillary muscles and trabeculæ.

In severe intoxications the process may be diffuse, and the entire

musculature appear cream-colored or yellowish and opaque. The

consistence may be firm, flabby, soft, putty-like; localized areas

may be caseous. Infarcted areas are soft when fresh (myomalacia

cordis). The consistence is increased in atrophy, fibroid heart,

chronic interstitial myocarditis, syphilis, etc. Cloudy swelling and

fatty degeneration make the heart muscle softer and more friable. In

postmortem decomposition the heart as a whole becomes soft. Normally

the endocardium should be gray, delicate, thin and transparent. The

chordæ tendinæ are long, narrow and delicate. Note thickenings of

endocardium and chordæ tendinæ, presence of thrombi (dry, brick-red,

yellowish or gray, firmer than clots and adherent to the endocardium,

often show simple softening, which should not be mistaken for pus;

may be parietal, polypoid, valvular or free). The endocardium may be

stained diffusely yellow (bile) or brown (methæmoglobin). Creamy or

yellowish opacities of the intima are due to fatty degeneration.

8. =Left Heart.= Note same things in left side of heart as on

right. In cardiac paralysis left ventricle is filled with blood

if rigor mortis has not set in. Left ventricle wall is 10-15 mm.

thick normally; may become 30 mm. thick in hypertrophy. Papillary

muscles and trabeculæ may be markedly hypertrophic, but in the

greatly dilated heart (aortic insufficiency) may be much flattened.

The septum of the ventricles may share in the hypertrophy of either

ventricle and when hypertrophic bulges into the cavity of the

unaffected side. Examine wall of left ventricle, particularly near

the apex, for infarcts, fibroid patches, aneurismal dilatation,

rupture, fatty degeneration, thrombi, etc. Look particularly for

pathologic conditions involving the atrioventricular bundle.

9. =Orifices and Valves.= Orifices should measure as

follows:—Tricuspid (12-12.7 cm.), mitral (10.4-10.9 cm.), pulmonary

(8.9-9.2 cm.), aorta (7.7-8 cm.). Rough measurements may be

taken with the fingers, tricuspid admitting three, mitral two,

pulmonary one and a half, aorta thumb. The orifices may be measured

by graduated cones, or in the ordinary way after the heart is

sectioned. Normally the edges of the valve-flaps should be delicate,

smooth and thin. Examine for vegetations, thrombi, induration,

thickening, contractions, ulcerations, tears, perforations, defects,

calcification, atheroma, valvular aneurism, etc. Note thickening,

contraction, adhesion, shortening, etc., of the chordæ tendinæ. When

the tendons are long, narrow and thread-like, and without adhesions,

the probabilities are that a lesion of the mitral orifice was not

present.

10. =Coronary Vessels.= Walls should be uniformly delicate and

thin, and the intima should be delicate, gray and transparent.

Note contents of arteries and veins. Examine arteries especially

for thrombi, emboli, arteriosclerosis, atheroma, calcification,

obliteration of lumen, thickening of wall, loss of elasticity,

opacity of intima and increased tortuosity of course.

The most important pathologic conditions of the heart

are:—endocarditis (ulcerosa, maligna, verrucosa, simplex, chronica

fibrosa, sclerosing), valvular insufficiency and stenosis,

hypertrophy, dilatation, atrophy, fatty infiltration, fatty

degeneration, cloudy swelling, anæmic infarction, calcification,

acute and chronic myocarditis, abscess, fibroid heart, cardiac

aneurism, rupture, thrombosis, embolism, malformations (septum

defects, patent ductus arteriosus, stenosis or atresia of orifices),

tuberculosis (not rare, in association with tuberculous pericarditis,

or general miliary tuberculosis), syphilis (gumma not common,

localized or diffuse interstitial myocarditis the most common

manifestation), actinomycosis, cysticercus, echinococcus, trichina

and neoplasms (primary rare, in part congenital, fibroma, lipoma,

angioma, myxoma, rhabdomyoma; secondary sarcoma less rare than

secondary carcinoma, most common forms are melanotic sarcoma and

lymphosarcoma).

11. =Left Lung.= Weighs 350-500 grm. _Size_ (voluminous, collapsed,

compare lobes); _form_ (edges rounded, sharp, nodular, saccular or

cystic, contractions, depressions, emphysematous enlargements);

_pleura_ (examine again more closely. Circumscribed dull-shining

or cloudy areas point to some pathologic condition of the lung

beneath. Look for evidences of healed tuberculosis, particularly

in the pleura of the apices. Secondary carcinoma of the pleura is

very common. Primary tumors are rare; endothelioma and sarcoma are

the most common forms. Small circumscribed areas of pigmentation

usually represent old tubercles); _color_ (depends upon degree of

anthracosis, blood-content and condition of pleura, areas showing

especial color should be examined closely; most common colors are

pinkish-gray normally, grayish, slaty, black, red, brown, dark-red

to black); _size of air-cells_ (normally can be seen with naked

eye, best seen at apex and borders, about size of pin-points, when

larger than the head of a pin they are emphysematous); _lobules_ can

also be seen with naked eye, usually polygonal in shape, 2-3 mm. in

diameter; _consistence_ (estimate by going over entire lung, pressing

the lung-substance between thumb and fingers; air-containing lung is

soft, elastic and crepitates; airless areas are hard, firm and do not

crepitate).

On the cut surface the following points should be noted:

_Blood-content_ (anæmia, hyperæmia, hypostatic congestion), _color

of cut-surface_, _air-content_, _exudate_ (serous, purulent),

_consistence_ (hard, soft, elastic, caseous, brittle, crumbling),

_character of surface_ (smooth, granular, nodular, cavities).

Cavities should be described according to their position, size,

shape, contents and character of their walls.

12. =Right Lung.= Weight 420-620 grms. Note size, form, color,

surface, size of air-cells, lobules, consistence, blood-content,

air-content, exudate, consistence and character of cut-surface, as in

case of left lung.

Evidences of healed tuberculosis are found in practically all

adult lungs in the form of localized thickenings or puckering

of the pleura, especially at the apices, hyaline or anthracotic

nodules, encapsulated, caseous or calcified tubercles. Old scars

and indurations are firm, hard and usually black in color. Caseous

areas are smooth, dry, white or grayish, and opaque. Very young

tubercles are elevated, grayish and translucent. Atelectatic areas

are depressed and bluish-red in color. Areas of hepatization are red

or gray, elevated, granular, crumbling, moist in early stage, dry in

caseous hepatization. In bronchopneumonia the areas of hepatization

are usually sharply circumscribed. Metastatic abscesses lie usually

beneath the pleura, are usually multiple and distributed over both

lungs. Bronchopneumonic areas are usually found in the dependent

portions, particularly in right lung. An abundance of foamy, watery

fluid on the cut-surface indicates œdema; when very bloody there

is usually a marked stasis or beginning hepatization present. In

atelectasis and fibrinous hepatization the exudate from the surface

is not foamy. Emphysematous areas are white or grayish-white and

are most frequently found along the borders. Large air-spaces are

often found along the interlobular septa (interstitial emphysema),

particularly in children following trauma, croup, whooping-cough,

etc. In chronic passive congestion the lung is firmer than normal,

deep-red or brownish in color. Hemorrhagic infarcts lie usually

beneath the pleura, are wedge-shaped, with base toward pleura, firm,

smooth on section, or granular, and when fresh are nearly black;

older ones are lighter and brownish. Cavities in the lung occur in

tuberculosis, embolic and primary abscesses, actinomycosis, gangrene,

bronchiectasis, primary and secondary tumors, etc. Gangrenous

areas have diffuse borders, are gray or greenish in color, with

central softened areas, with ragged borders and stinking smell. In

bronchiectatic cavities the smooth mucosa of the bronchus passes

directly into the wall of the cavity. Primary carcinomata of the

lungs appear as cavities having a white medullary wall, or as

medullary strands running along the bronchi. Tuberculous cavities

have caseous walls, are more or less encapsulated, and usually

show younger tubercles in the neighborhood of the wall. Antemortem

hypostasis is usually darker and firmer than postmortem, and is

usually associated with inflammation (hypostatic pneumonia).

The most important pathologic conditions of the lungs are:—Anomalies

(anomalous lobes common, infradiaphragmatic accessory lungs,

agenesia, congenital bronchiectasis), atelectasis (fœtal,

compression, obstruction, paralytic, etc.), emphysema (acute,

chronic, vicarious, senile, atrophic, hypertrophic, interstitial,

gangrenous), hyperæmia, stasis, brown induration, hypostasis,

œdema (universal, stasis, hypostatic, atelectatic, acute, chronic,

terminal), hemorrhage, hemorrhagic infarction, thrombosis, embolism,

fatty embolism, pneumonia (croupous, atypical, bronchopneumonia,

acute and chronic interstitial), abscess, gangrene, tuberculosis

(acute miliary, caseous pneumonia, peribronchial, tuberculous

bronchopneumonia, indurative, fibroid, phthisis pulmonum), syphilis

(gumma, white pneumonia), actinomycosis, neoplasms (primary

adenoma, lipoma, papilloma, chondroma, osteoma, sarcoma, carcinoma

and teratoma are rare; metastatic sarcoma and carcinoma are

common; malignant chorio-epithelioma is not infrequent), parasites

(echinococcus, cysticercus, hook-worm embryos, pentastomum and

distomum pulmonale).

13. =Bronchi.= Note size, contents, thickness of wall, color and

thickness of mucosa. Normally the bronchi are empty, and the mucosa

grayish-red. In pulmonary œdema they contain clear, foamy fluid;

in bronchitis they may contain a mucous, mucopurulent, purulent,

fibrinous, hemorrhagic or putrid exudate. In acute bronchitis the

mucosa is red; in chronic bronchitis the mucosa may be red or

brownish, and thickened or folded. Material from the stomach may

enter the bronchi postmortem and cause a postmortem digestion of the

mucosa or wall.

The most important pathologic conditions of the bronchi

are:—Inflammation (acute and chronic catarrhal bronchitis, fibrinous,

putrid, atrophic, obliterans), bronchial asthma, tuberculosis,

syphilis, stenosis, bronchiectasis, perforation (aneurisms, abscess,

carcinoma, tubercles, etc.), bronchial calculi, foreign bodies,

neoplasms (adenoma, papilloma, carcinoma, chondroma, osteoma),

parasites (cysticercus, echinococcus, hook-worm embryos, distomum

pulmonale, pentastomum).

14. =Bronchial Glands.= Note size, pigmentation (gray, dark-gray,

black), consistence, character of cut-surface, caseation, fibroid

induration, calcification, œdema, congestion, abscess, neoplasm.

Tuberculosis and secondary neoplasms are the most common conditions.

Lymphosarcoma is the most frequent primary tumor.

15. =Pulmonary Vessels.= Character of walls and contents. Normally

the intima is smooth, grayish-white and translucent. Fatty

degeneration of the intima is not rare (acute infections and

intoxications); atheroma and aneurismal dilatation are infrequent.

Occasionally parietal thrombi and thickening of the wall due to

organization of a thrombus are seen. The pulmonary arteries are

normally empty or contain soft cruor or agonal white clots. These

are not adherent to the wall, do not fill the lumen and are soft and

moist. Emboli fill the lumen as if forced into it (at the branchings

of the artery they form “rider’s” emboli); they are more dry and

brick-red, brownish or grayish in color. Occasionally they may be

unrolled into long fibrinous strands. Older emboli may show more or

less organization and adherence to the vessel-wall. In air-embolism

the pulmonary arteries contain a mixture of blood and air looking

like a stiff-beaten white of egg of red color. Large emboli of

liver-tissue or liver-cells may be found in the pulmonary arteries

after traumatic rupture of the liver. Fat-emboli of the smaller

arteries can be recognized by the naked-eye. Thrombosis of both

pulmonary arteries and veins is very common in chronic valvular

lesions, pneumonia, terminal infections, burns of the skin, poisoning

with hemolytic agents, etc.

16. =Great Vessels of Thorax.= Note size of lumen, condition of

walls, particularly of intima, and the contents. Circumference

of thoracic aorta 4.5-6.0 cm., thickness of wall 1.5-2 mm. Test

elasticity of wall by stretching; note if it retracts and becomes

shorter than the œsophagus, which was cut at the same level. Note

consistence of wall (stiff and hard in sclerosis and calcification).

Normally the intima of the aorta is smooth, grayish-white and

semitranslucent; the wall is elastic. Fatty degeneration, sclerosis,

atheroma and aneurismal dilatations are the most common pathologic

findings. Fatty degeneration shows itself in yellowish spots or

streaks, more opaque and slightly elevated. Sclerotic areas are hard,

white and tendon-like. Atheromatous “plaques” and “ulcers” are white

or yellowish, elevated, rough, scaly, with loss of substance, often

more or less calcified. Thrombi are frequently formed upon such

atheromatous patches. Hemorrhage into the intima may occur (aneurysma

dissecans). Radiating or linear sclerotic folds and depressions

in the intima, with or without dilatation of the lumen, usually

result from syphilis (mesaortitis). A dirty brownish discoloration

of the intima is due to an imbibition of diffuse hæmoglobin, usually

postmortem. In chronic icterus the intima may be bile-stained.

Thrombosis of the aorta is not common. Congenital or acquired

stenosis at the isthmus is rare. Tuberculosis of the aorta-wall is

also very rare.

17. =Thoracic Portion of Oesophagus.= Note size (stenosis,

dilatation, diverticulum), contents (food, stomach-contents, blood,

pus, foreign-body), thickness of wall, color of mucosa (normally

grayish-white), neoplasms (carcinoma), perforations, erosions

(aneurism, abscess, neoplasm), inflammation. Anomalies, tuberculosis,

syphilis, actinomycosis and neoplasms (with the exception of

carcinoma) are rare. The most common location of carcinoma is

toward the cardia. Thrush is the most common parasite. Varices of

the œsophageal veins are common, and from these fatal hemorrhages

may occur. In the thoracic portion they are usually the result of

collateral distention to offset a portal stasis (hepatic cirrhosis,

Banti’s disease, thrombosis of splenic or portal veins). The passage

of stomach-contents through the cardia into the œsophagus may cause a

postmortem softening or perforation of the œsophageal wall.

18. =Thoracic Duct.= Note size, contents and character of wall.

Tuberculosis, malignant neoplasms, obstruction, rupture and purulent

inflammations are the most important pathologic conditions. In

miliary tuberculosis the thoracic duct may be the primary focus

or the avenue by which the bacilli enter the blood. The duct also

plays an important part in the dissemination of malignant tumors and

infections from the abdominal cavity and pelvis. Chylothorax and

chylopericardium are usually caused by the blocking of the thoracic

duct by malignant neoplasms (lymphosarcoma, carcinoma), or by rupture

of the duct.

19. =Thoracic Vertebrae.= Note surfaces of vertebræ (normally

smooth), curvatures, softening, erosions, exostoses, neoplasms,

fractures, dislocations. Tuberculosis, curvatures and malignant

tumors (secondary carcinoma, primary sarcoma, myeloma, chloroma) are

the most common conditions. Aneurismal erosions are not rare.

Practical pathology · 第 8 / 18 章