Wolfgang von Goethe

We have mentioned previously that there are two main types of nucleic

acids: DNA, the genetic material itself, and RNA, the molecule that

translates the genetic message from DNA into terms the cell can use as

“instructions” for making protein. Cells differ from each other on the

basis of kinds of proteins they contain, and, since differences among

cells determine differences among organisms, it follows that differences

in the composition of DNA serve to explain the variety in living

organisms populating the world. However, if differences between two

organisms can be explained by differences in the chemical composition of

their respective DNA’s, how can we explain differences between cells of

the same organism? How can we explain that cells of the human pancreas

secrete insulin, whereas other cells in man produce no insulin? Or how

can we explain that certain cells make bone and others make fat? If

indeed all cells in the same organism contain the same amount and kind

of DNA (since all DNA in an organism derives from the duplication of the

DNA of the fertilized egg cell and its descendants), it would seem, at

first glance, that DNA is not the molecule responsible for differences

among the cells. The clarification of this apparent contradiction is

found in the remarkable properties of the other nucleic acid, the

translator molecule, RNA.

Radioisotopes and Life Processes (Revised) · 第 27 / 59 题