Bleeding: The History

The history of bloodletting has been marked by controversy. The extensive

literature on bloodletting contains numerous polemical treatises that both

extol and condemn the practice. Bloodletting was no sooner criticized as

ineffective and dangerous than it was rescued from complete abandonment by

a new group of zealous supporters.

From the time of Hippocrates (5th century B.C.)--and probably before,

although no written record is available--bloodletting had its vocal

advocates and heated opponents. In the 5th century B.C. Aegimious of Eris

(470 B.C.), author of the first treatise on the pulse, opposed

venesection, while Diogenes of Appolonia (430 B.C.), who described the

vena cava with its main branches, was a proponent of the practice.

Hippocrates, to whom no specific text on bloodletting is attributed, both

approved and recommended venesection.[3]

The anatomist and physician Erasistratus (300-260 B.C.), was one of the

earliest physicians to leave a record of why he opposed venesection, the

letting of blood from a vein. Erasistratus, who practiced at the court of

the King of Syria and later at Alexandria, a celebrated center of ancient

medicine, recognized that the difficulty in estimating the amount of blood

to be withdrawn and the possibility of mistakenly cutting an artery,

tendon, or nerve might cause permanent damage or even death. Since

Erasistratus believed that only the veins carried blood while the arteries

contained air, he also feared the possibility of transferring air from the

arteries into the veins as a result of venesection. Erasistratus was led

to question how excessive venesection differed from committing murder.[4]

Through the writings of Aulus Cornelius Celsus (25 B.C.-?), the Roman

encyclopedist, and Galen (ca. A.D. 130-200) venesection was restored as a

form of orthodox medical treatment and remained so for the next fifteen

hundred years. By the time of Celsus, bloodletting had become a common

treatment. Celsus remarked in his well-known account of early medicine:

"To let blood by incising a vein is no novelty; what is novel is that

there should be scarcely any malady in which blood may not be let."[5] Yet

criticism of bloodletting continued, for when Galen went to Rome in A.D.

164 he found the followers of Erasistratus opposing venesection. Galen

opened up discussion with these physicians in two books, _Against

Erasistratus_ and _Against the Erasistrateans Dwelling in Rome_. These

argumentative dialectical treatises, together with his _Therapeutics of

Venesection_, in which he presented his theory and practice of

venesection, established Galen's views on bloodletting, which were not

effectively challenged until the seventeenth century.[6]

The fundamental theory upon which explanations of health and disease were

based, which had its inception in ancient Greek thought and lasted up to

the eighteenth century, was the humoral theory. Based on the scientific

thought of the Pre-Socratics, the Pythagoreans, and the Sicilians, this

theory posited that when the humors, consisting of blood, phlegm, yellow

bile, and black bile, were in balance within the body, good health ensued.

Conversely, when one or more of these humors was overabundant or in less

than adequate supply, disease resulted. The humors were paired off with

specific qualities representing each season of the year and the four

elements according to the well-accepted doctrine of Empedocles, in which

all things were composed of earth, air, fire, and water. Thus, yellow

bile, fire, and summer were contrasted to phlegm, water, and winter, while

blood, air, and spring were contrasted to black bile, earth, and autumn.

When arranged diagrammatically, the system incorporating the humors,

elements, seasons, and qualities appears as shown in Figure 1. The

earliest formulation of humoralism was to be found in the physiological

and pathological theory of the Hippocratic treatise, _On the Nature of

Man_.[7]

Plethora, an overabundance of body humors, including blood, which

characterized fevers and inflammations, was properly treated by

encouraging evacuation. This could be done through drugs that purged or

brought on vomiting, by starvation, or by letting blood. During starvation

the veins became empty of food and then readily absorbed blood that

escaped into the arteries. As this occurred, inflammation decreased. Galen

suggested that instead of starvation, which required some time and

evacuated the system with much discomfort to the patient, venesection

should be substituted to remove the blood directly.[8]

Peter Niebyl, who has traced the rationale for bloodletting from the time

of Hippocrates to the seventeenth century, concluded that bloodletting was

practiced more to remove excess good blood rather than to eliminate

inherently bad blood or foreign matter. Generally, venesection was

regarded as an equivalent to a reduction of food, since according to

ancient physiological theory, food was converted to blood.[9]

[Illustration: FIGURE 1.--Chart of elements, seasons, and humors.]

Galen defined the criteria for bloodletting in terms of extent, intensity,

and severity of the disease, whether the disease was "incipient,"

"present," or "prospective," and on the maturity and strength of the

patient.[10] Only a skilled physician would thus know when it was proper

to bleed a patient. Venesection could be extremely dangerous if not

correctly administered, but in the hands of a good physician, venesection

was regarded by Galen as a more accurate treatment than drugs. While one

could measure with great accuracy the dosages of such drugs as emetics,

diuretics, and purgatives, Galen argued that their action on the body was

directed by chance and could not easily be observed by the physician.[11]

However, the effects of bloodletting were readily observed. One could note

the change in the color of the blood removed, the complexion of the

patient, and the point at which the patient was about to become

unconscious, and know precisely when to stop the bleeding.

Galen discussed in great detail the selection of veins to open and the

number of times blood might be withdrawn.[12] In choosing the vein to

open, its location in respect to the disease was important. Galen

recommended that bleeding be done from a blood vessel on the same side of

the body as the disease. For example, he explained that blood from the

right elbow be removed to stop a nosebleed from the right nostril.[13]

Celsus had argued for withdrawing blood near the site of the disease for

"bloodletting draws blood out of the nearest place first, and thereupon

blood from more distant parts follows so long as the letting out of blood

is continued."[14]

Controversy over the location of the veins to be opened erupted in the

sixteenth century. Many publications appeared arguing the positive and

negative aspects of bleeding from a vein on the same side

(derivative--from the Latin _derivatio_ from the verb _derivare_, "to draw

away," "to divert") or the opposite side (revulsion--from the Latin

_revulsio_, "drawing in a contrary direction") of the disordered part of

the body. This debate mirrored a broader struggle over whether to practice

medicine on principles growing out of medieval medical views or out of

classical Greek doctrines that had recently been revived and brought into

prominence. The medieval practice was based on the Moslem medical writers

who emphasized revulsion (bleeding from a site located as far from the

ailment as possible).[15] This position was attacked in 1514 by Pierre

Brissot (1478-1522), a Paris physician, who stressed the importance of

bleeding near the locus of the disease (derivative bleeding). He was

declared a medical heretic by the Paris Faculty of Medicine and derivative

bleeding was forbidden by an act of the French parliament. In 1518,

Brissot was exiled to Spain and Portugal. In 1539, the celebrated

anatomist, Andreas Vesalius, continued the controversy with his famous

_Venesection Letter_, which came to the support of Brissot.[16]

Only with the gradual awareness of the implications of the circulation of

the blood (discovered in 1628) did discussion of the distinction between

derivative and revulsive bloodletting become passe.[17] Long after the

circulation of the blood was established, surgical treatises such as those

of Lorenz Heister (1719) recommended removing blood from specific parts of

the body--such as particular veins in the arm, hand, foot, forehead,

temples, inner corners of the eye, neck, and under the tongue. In the

nineteenth century this practice was still challenged in the literature as

a meaningless procedure.[18] (Figure 2.)

_How Much Blood to Take_

According to Galen, safety dictated that the first bloodletting be kept to

a minimum, if possible. Second, third, or further bleedings could be taken

if the condition and the patient's progress seemed to indicate they would

be of value. The amount of blood to be taken at one time varied

widely.[19]

Galen appears to have been the first to note the amount of blood that

could be withdrawn: the greatest quantity he mentions is one pound and a

half and the smallest is seven ounces. Avicenna (980-1037) believed that

ordinarily there were 25 pounds of blood in a man and that a man could

bleed at the nose 20 pounds and not die.[20]

The standard advice to bloodletters, especially in the eighteenth and

nineteenth centuries, was "bleed to syncope." "Generally speaking," wrote

the English physician and medical researcher, Marshall Hall, in 1836, "as

long as bloodletting is required, it can be borne; and as long as it can

be borne, it is required."[21] The American physician, Robley Dunglison,

defined "syncope" in his 1848 medical dictionary as a "complete and,

commonly, sudden loss of sensation and motion, with considerable

diminution, or entire suspension of the pulsations of the heart and the

respiratory movements."[22] Today little distinction is made between shock

and collapse, or syncope, except to recognize that if collapse or syncope

persists, shock will result.

We know today that blood volume is about one-fifteenth to one-seventeenth

the body weight of an adult. Thus an adult weighing 150 pounds has 9 or 10

pounds of blood in his body. Blood volume may increase at great heights,

under tropical conditions, and in the rare disease polycythemia (excess

red blood cells). After a pint of blood is withdrawn from a healthy

individual, the organism replaces it to some degree within an hour or so.

However, it takes weeks for the hemoglobin (the oxygen-bearing substance

in the red blood cells) to be brought up to normal.

If blood loss is great (more than 10 percent of the total blood volume)

there occurs a sudden, systemic fall in blood pressure. This is a

well-known protective mechanism to aid blood clotting. If the volume of

blood lost does not exceed 30 to 40 percent, systolic, disastolic, and

pulse pressures rise again after approximately 30 minutes as a result of

various compensatory mechanisms.[23]

[Illustration: FIGURE 2.--Venesection manikin, 16th century. Numbers

indicate locations where in certain diseases venesection should be

undertaken. (From Stoeffler, 1518, as illustrated in Heinrich Stern,

_Theory and Practice of Bloodletting_, New York, 1915. Photo courtesy of

NLM.)]

If larger volumes than this are removed, the organism is usually unable to

survive unless the loss is promptly replaced. Repeated smaller bleedings

may produce a state of chronic anemia when the total amount of blood and

hemoglobin removed is in excess of the natural recuperative powers.

_When to Bleed_

Selecting a time for bleeding usually depended on the nature of the

disease and the patient's ability to withstand the process. Galen's

scheme, in contrast to the Hippocratic doctrine, recommended no specific

days.[24] Hippocrates worked out an elaborate schedule, based on the onset

and type of disease, to which the physician was instructed to adhere

regardless of the patient's condition.

Natural events outside the body served as indicators for selecting the

time, site, and frequency of bloodletting during the Middle Ages when

astrological influences dominated diagnostic and therapeutic thought. This

is illustrated by the fact that the earliest printed document relating to

medicine was the "Calendar for Bloodletting" issued in Mainz in 1457. This

type of calendar, also used for purgation, was known as an

_Aderlasskalender_, and was printed in other German cities such as

Augsburg, Nuremberg, Strassburg, and Leipzig. During the fifteenth century

these calendars and _Pestblatter_, or plague warnings, were the most

popular medical literature. Sir William Osler and Karl Sudhoff studied

hundreds of these calendars.[25] They consisted of a single sheet with

some astronomical figures and a diagram of a man (_Aderlassmann_)

depicting the influence of the stars and the signs of the zodiac on each

part of the body, as well as the parts of the anatomy suitable for

bleeding. These charts illustrated the veins and arteries that should be

incised to let blood for specific ailments and usually included brief

instructions in the margin. The annotated bloodletting figure was one of

the earliest subjects of woodcuts. One early and well known _Aderlassmann_

was prepared by Johann Regiomontanus (Johannes Mueller) in 1473. It

contained a dozen proper bleeding points, each suited for use under a

sign of the zodiac. Other _Aderlassmanner_ illustrated specific veins to

be bled. The woodcut produced by the sixteenth-century mathematician,

Johannes Stoeffer, illustrated 53 points where the lancet might be

inserted.[26]

"Medicina astrologica" exerted a great influence on bloodletting.

Determining the best time to bleed reached a high degree of perfection in

the late fourteenth and fifteenth centuries with the use of volvella or

calculating devices adopted from astronomy and navigation. These were

carried on a belt worn around the waist for easy consultation. Used in

conjunction with a table and a vein-man drawing, the volvella contained

movable circular calculators for determining the accuracy, time, amount,

and site to bleed for an illness. The dangers of bloodletting elicited

both civic and national concern and control. Statutes were enacted that

required every physician to consult these tables before opening a vein to

minimize the chance of bleeding improperly and unnecessarily. Consultation

of the volvella and vein-man was more important than an examination of the

patient.[27] (Figure 3.)

For several centuries, almanacs were consulted to determine the propitious

time for bleeding. The "woodcut anatomy" became a characteristic

illustration of the colonial American almanac. John Foster introduced the

"Man of Signs," as it was called, into the American almanac tradition in

his almanac for 1678, printed in Boston. Other examples of early American

almanacs featuring illustrations of bleeding include Daniel Leed's almanac

for 1693, printed in Philadelphia, and John Clapp's almanac for 1697,

printed in New York.

As in many of the medieval illustrations, the woodcut anatomy in the

American almanac consisted of a naked man surrounded by the twelve signs

of the zodiac, each associated with a particular part of the body (the

head and face with Aries, the neck with Taurus, the arms with Gemini,

etc.). The directions that often accompanied the figure instructed the

user to find the day of the month in the almanac chart, note the sign or

place of the moon associated with that day, and then look for the sign in

the woodcut anatomy to discover what part of the body is governed by that

sign. Bloodletting was usually not specifically mentioned, but it is

likely that some colonials still used the "Man of Signs" or "Moon's Man"

to determine where to open a vein on a given day.[28]

[Illustration: FIGURE 3.--Lunar dial, Germany, 1604. Concentric scales

mark hours of the day, days, months, and special astrological numbers. In

conjunction with other dials, it enables the user to determine the phases

of the moon. (NMHT 30121; SI photo P-63426.)]

The eighteenth-century family Bible might contain a list of the favorable

and unfavorable days in each month for bleeding, as in the case of the

Bible of the Degge family of Virginia.[29]

_Barber-Surgeons_

Even though it was recognized that bleeding was a delicate operation that

could be fatal if not done properly, it was, from the medieval period on,

often left in the hands of the barber-surgeons, charlatans, and women

healers. In the early Middle Ages the barber-surgeons flourished as their

services grew in demand. Barber-surgeons had additional opportunities to

practice medicine after priests were instructed to abandon the practice of

medicine and concentrate on their religious duties. Clerics were cautioned

repeatedly by Pope Innocent II through the Council at Rheims in 1131, the

Lateran Council in 1139, and five subsequent councils, not to devote time

to duties related to the body if they must neglect matters related to the

soul.[30]

By 1210, the barber-surgeons in England had gathered together and formed a

Guild of Barber-Surgeons whose members were divided into Surgeons of the

Long Robe and Lay-Barbers or Surgeons of the Short Robe. The latter were

gradually forbidden by law to do any surgery except bloodletting, wound

surgery, cupping, leeching, shaving, extraction of teeth, and giving

enemas.[31] The major operations were in the hands of specialists, often

hereditary in certain families, who, if they were members of the Guild,

would have been Surgeons of the Long Robe.

[Illustration: FIGURE 4.--Bleeding bowl with gradations to measure the

amount of blood. Made by John Foster of London after 1740. (Held by the

Division of Cultural History, Greenwood Collection, Smithsonian

Institution; SI photo 61166-C.)]

To distinguish his profession from that of a surgeon, the barber-surgeon

placed a striped pole or a signboard outside his door, from which was

suspended a basin for receiving the blood (Figure 4). Cervantes used this

type of bowl as the "Helmet of Mambrino" in Don Quixote.[32] Special

bowls to catch the blood from a vein were beginning to come into fashion

in the fourteenth century. They were shaped from clay or thin brass and

later were made of pewter or handsomely decorated pottery. Some pewter

bowls were graduated from 2 to 20 ounces by a series of lines incised

around the inside to indicate the number of ounces of fluid when filled to

that level. Ceramic bleeding bowls, which often doubled as shaving bowls,

usually had a semicircular indentation on one side to facilitate slipping

the bowl under the chin. Bowls to be used only for bleeding usually had a

handle on one side. Italian families had a tradition of passing special

glass bleeding vessels from generation to generation. The great variety in

style, color, and size of bleeding and shaving bowls is demonstrated by

the beautiful collection of over 500 pieces of Dr. A. Lawrence Abel of

London and by the collection of the Wellcome Historical Museum, which has

been cataloged in John Crellin's _Medical Ceramics_.[33] These collections

illustrate the stylistic differences between countries and periods.

The barber-surgeons' pole represented the stick gripped by the patient's

hand to promote bleeding from his arm. The white stripe on the pole

corresponded to the tourniquet applied above the vein to be opened in the

arm or leg. Red or blue stripes appeared on early barber poles, but later

poles contained both colors.[34]

The dangers posed by untutored and unskilled bleeders were noted

periodically. In antiquity Galen complained about non-professional

bleeders, and in the Middle Ages, Lanfranc (1315), an outstanding surgeon,

lamented the tendency of surgeons of his time to abandon bloodletting to

barbers and women.[35] Barber-surgeons continued to let blood through the

seventeenth century. In the eighteenth and nineteenth centuries, the

better educated surgeon, and sometimes even the physician, took charge of

bleeding.

_Bloodletting and the Scientific Revolution_

The discovery of the blood's circulation did not result in immediate

changes in the methods or forms of bloodletting. William Harvey, who

published his discovery of circulation in 1628, recognized the value of

investigating the implications of his theory. Harvey could not explain the

causes and uses of the circulation but he believed that it did not rule

out the practice of bloodletting. He claimed that

daily experience satisfies us that bloodletting has a most salutary

effect in many diseases, and is indeed the foremost among all the

general remedial means: vitiated states and plethora of blood, are

causes of a whole host of disease; and the timely evacuation of a

certain quantity of the fluid frequently delivers patients from very

dangerous diseases, and even from imminent death.[36]

The English scientist Henry Stubbe brought to the surface what would

appear to be an obvious dilemma: How could one bleed to produce local

effect if the blood circulated? Stubbe commented in 1671:

I do say, that no experienced Physician ever denied the operation of

bloodletting though since the tenet of the Circulation of the Blood

the manner how such an effect doth succeed admits of some dispute,

and is obscure. We the silly followers of Galen and the Ancients do

think it an imbecility of judgement, for any to desert an experienced

practice, because he doth not comprehend in what manner it is

effected.[37]

In the early nineteenth century the physiologist Francois Magendie

(1783-1855), who argued against bloodletting, showed that the

physiological effects of opening different veins was exactly the same, and

therefore the choice of which vein to bleed did not affect the

procedure.[38]

The first serious modern challenges to bloodletting were made in the

sixteenth and seventeenth centuries under the leadership of the German

alchemist Paracelsus and his Belgian follower, Van Helmont. The medical

chemists or iatrochemists espoused explanations for and treatments of

diseases based on chemical theories and practices. They believed that the

state of the blood could best be regulated by administering the proper

chemicals and drugs rather than by simply removing a portion of the blood.

Iatrochemistry provided a substitution in the form of medicinals to quell

the flow of blood for therapeutic purposes.[39]

The revival of Hippocratic medicine in the late seventeenth and eighteenth

centuries also led to questioning the efficacy of bloodletting. The

Hippocratic treatises, while they occasionally mentioned bloodletting,

generally stressed nature's power of cure. This school of medicine

advocated a return to clinical observation and a reduction of activist

intervention. Treatments such as bloodletting, it was felt by the

neo-Hippocratists, might merely serve to weaken the patient's strength

and hinder the healing processes of nature.[40]

A rival group of medical theorists also flourished in this period. The

iatrophysicists, who concentrated on mechanical explanations of

physiological events, remained adherents of bloodletting. Their support of

the practice ensured its use at a time when the first substantial

criticism of it arose.

_Instrumentation and Techniques_

Sharp thorns, roots, fish teeth, and sharpened stones were among the early

implements used to let blood.[41] Venesection, one of the most frequently

mentioned procedures in ancient medicine, and related procedures such as

lancing abcesses, puncturing cavities containing fluids, and dissecting

tissues, were all accomplished in the classical period and later with an

instrument called the phlebotome. _Phlebos_ is Greek for "vein," while

"tome" derives from _temnein_, meaning "to cut." In Latin, "phlebotome"

becomes "flebotome," and in an Anglo-Saxon manuscript dating from A.D.

1000, the word "fleam" appears. The phlebotome, a type of lancet, was not

described in any of the ancient literature, but its uses make it apparent

that it was a sharp-pointed, double-edged, and straight-bladed cutting

implement or scalpel similar to the type later used for splitting larger

veins.[42]

Several early Roman examples of phlebotomes have been collected in

European museums. One, now in the Cologne Museum, was made of steel with a

square handle and blade of myrtle leaf shape. Another specimen, made of

bronze, was uncovered in the house of the physician of _Strada del

Consulare_ of Pompeii. This specimen, now in the Naples Museum, is 8 cm

long and 9 mm at the broadest part of the blade, and its handle bears a

raised ring ornamentation.[43] A number of copies of Roman instruments

have been made and some have passed into museum collections. Some of the

copies were commissioned by Sir Henry Wellcome for the Wellcome Historical

Medical Museum collection and the Howard Dittrick Historical Medical

Museum in Cleveland. They emulate the size, color, and aged condition of

the originals and make it very difficult for the inexpert to distinguish

an original from its replica. It is, however, impossible to fully

duplicate the patina of ancient bronze.[44] Seventeenth-century and later

bloodletting instruments usually have not been copied.[45]

From the earliest examples of the fleam, such as the specimen found at

Pompeii, this instrument has been associated with the veterinarian. Since

early practitioners, particularly the Roman physician, performed the

duties of the surgeon as well as those of the veterinarian, it is possible

that they used the same instrument to open blood vessels in humans and

animals.[46]

In the seventeenth and eighteenth centuries a type of fleam (German

_fliete_, French _flamette_), which had a pointed edge at right angles to

the handle, was in use in Germany, Holland, and Vienna, Austria.[47] Since

the specimens found in museums vary in size, it is likely that this type

of fleam was used on both animals and humans.

In about the fifteenth century the thumb lancet, also called a

_gladiolus_, _sagitella_, _lanceola_, _lancetta_, or _olivaris_, was

introduced.[48] It soon became the preferred instrument for opening a vein

in any part of the body. The double-edged iron or steel blade was placed

between two larger covers, usually made of horn or shell, and all three

pieces were united at the base with a riveted screw. The blade could be

placed at various angles of inclination when in use. The shape of the

blade, whether broad or narrow, determined the ease with which the skin

and vein could be penetrated. A long slender blade was essential to pierce

a vein located below many layers of fatty tissue.[49] These tiny and

delicate thumb lancets were often carried in small flat cases of silver,

tortoise shell, shagreen, or leather with hinged tops and separate

compartments for each lancet. (Figure 5.)

A surgeon was advised to carry lancets of various sizes and shapes in

order to be prepared to open veins of differing sizes and in different

locations. Even Hippocrates had cautioned bloodletters not to use the

different size lancets indiscriminately, "for there are certain parts of

the body which have a swift current of blood which it is not easy to

stop."[50] For vessels that bled easily, it was essential to make narrow

openings; otherwise it would be difficult, if not impossible, to stop the

flow of the blood. For other vessels, lancets that made larger openings

were required or the blood would not flow satisfactorily.

The blood as it spurted from the vein would be collected in a container

and measured. When enough blood was removed, the bleeding would be

stopped by a bandage or compress applied to the incision.

[Illustration: FIGURE 5.--18th-19th century lancets and lancet cases. The

cases are made of mother-of-pearl, silver, shagreen, and tortoise shell.

(NMHT 308730.10. SI photo 76-9116.)]

Teaching a medical student how to bleed has had a long tradition. Before

approaching a patient, the student practiced opening a vein quickly and

accurately on plants, especially the fruits and stems.[51] The mark of a

good venesector was his ability not to let even a drop of blood be seen

after the bleeding basin was removed.[52]

It required some degree of skill to strike a vein properly. The most

common vein tapped was in the elbow, although veins in the foot were also

popular. The arm was first rubbed and the patient given a stick to grasp.

Then a tourniquet would be applied above the elbow (or, if the blood was

to be taken from the foot, above the ankle), in order to enlarge the veins

and promote a continuous flow of blood. Holding the handle between the

thumb and the first finger, the operator then jabbed the lancet into the

vein. Sometimes, especially if the vein was not close to the surface of

the skin, the instrument was given an extra impetus by striking it with a

small mallet or the fingers to insure puncturing the vein.[53] The

incisions were made diagonally or parallel to the veins in order to

minimize the danger of cutting the vein in two.[54]

For superficial veins, the vein was sometimes transfixed, that is, the

blade would be inserted underneath the vessel so that the vessel could not

move or slip out of reach. The transfixing procedure ensured that the vein

would remain semi-divided so that blood would continuously pass out of it,

and that injury to other structures would be avoided. Deep-lying veins of

the scalp, for example, could not be transfixed. They were divided by

cutting through everything overlying them since there were no important

structures to injure.[55]

The consequences of puncturing certain veins incorrectly were discussed by

many early writers including Galen, Celsus, Antyllus, and Paul of

Aegina.[56] Injury to a nearby nerve, muscle, or artery resulted in

convulsions, excessive bleeding, or paralysis.

Bloodletting was at its most fashionable in the eighteenth and early

nineteenth centuries. In this period it was considered an art to hold the

lancet properly and to support the arm of the patient with delicacy and

grace.[57] Many patients had by repeated bloodlettings become inured to

its potential danger and unpleasantness. In the mid-eighteenth century one

British physician declared: "People are so familiarized to bleeding that

they cannot easily conceive any hurt or danger to ensue, and therefore

readily submit, when constitutional fear is out of the question, to the

opening of a vein, however unskillfully advised."[58] In England in the

early nineteenth century people came to the hospital to be bled in the

spring and fall as part of the ritual for maintaining good health. At some

periods there were so many people undergoing prophylactic bloodletting

that they could be seen lying on the floor of the hospital while

recovering from the faintness induced by venesection.[59]

The lancet was perhaps the most common medical instrument. _The Lancet_

was the name of one of the oldest and most socially aware English medical

journals, founded by Thomas Wakeley in 1823.[60]

In America, Benjamin Rush (1746-1813) promoted vomits, purges, salivation,

and especially bleeding. Rush, a signer of the Declaration of

Independence, is notorious in medical history for his resorting to massive

bleedings during the epidemics of yellow fever at the end of the

eighteenth century. Rush told a crowd of people in 1793: "I treat my

patients successfully by bloodletting, and copious purging with calomel

and jalop and I advise you, my good friends, to use the same remedies."

"What?" called a voice from the crowd, "Bleed and purge everyone?" "Yes,"

said the doctor, "bleed and purge all Kensington."[61]

The alternatives to bleeding in this period included administering mercury

(calomel) to promote salivation and tartar emetic to induce vomiting.

These substitutes could be as hazardous as bleeding and offered little

choice to the patient who had to bear the unpleasant effects. Thus, the

late eighteenth and early nineteenth century has been referred to by

historians as the era of heroic medicine because of the large amounts of

strong medications given and excessive bloodletting.[62]

One of the most notable victims of heroic medicine during this period was

George Washington (1732-1799), who was bled four times in two days after

having contracted a severe inflammation of the throat. Washington's

physician, Dr. Craik, admitted that the removal of too much blood might

have been the cause of his death. Additional bleeding was prevented only

by Washington's request to be allowed to die without further medical

intervention, since he believed that his illness was incurable.[63]

Bloodletting was especially resorted to in times of crisis. One woman,

Hannah Green, had been anesthetized in 1848 by chloroform before

undergoing a minor operation on her toe. The physician bled her in a

futile attempt to revive her, but she died, becoming the first known

victim of inhalation anesthesia.[64]

_Spring Lancets_

The great vogue in phlebotomy inspired the invention of ingenious

instruments. From Vienna came the automatic or spring lancet, originally

called a _Schnepper_ or _Schnepperlein_, which permitted the operator to

inject the blade into a vein without exerting manual pressure.[65] It was

widely adopted if the variety of models now extant is a proper indication.

In the spring lancet, the blade was fixed into a small metal case with a

screw and arranged to respond to a spring that could be released by a

button or lever on the outside of the case. The blade was positioned at

right angles to the spring and case, thus adopting the basic shape of the

fleam. The case of the spring lancet was usually made of copper, silver,

brass, or an alloy. It was often decorated with engraved furbelows or

embossed with political or other symbols depending on the preference of

the owner and the fashion of the period. The mechanism of this handsome

implement has been described by a modern collector (Figures 6, 7):

The curved projection (1) is the continuation of a heavy coiled

spring. When pushed up it catches on a ratchet. A razor sharp blade

(2), responding to the pressure of a light spring placed under it,

follows the handle as it goes up. A lever (3) acting on a fulcrum (4)

when pressed down, releases handle which in turn strikes the lancet

down with lightning speed.[66]

The spring lancet was initially described by Lorenz Heister in 1719.[67]

Another early description appeared in 1798 in the first American edition

of the _Encyclopedia or Dictionary of Arts and Sciences_, in which the

spring lancet was called a "phleam."[68]

The spring lancet for use on humans was a rather tiny instrument. Its

casing was about 4 cm long and 1.5 to 2 cm wide. The blade added

another centimeter in length. Larger size instruments, often with a metal

guard over the blade, were made for use on animals. Eighteenth- and early

nineteenth-century spring lancets are found in a wide variety of shapes.

Mid- and late nineteenth-century spring lancets are more uniform in shape,

most having the familiar knob-shaped end. In most lancets the blade was

released by a lever, but in the late nineteenth century, the blade of a

more expensive model was released by a button.

[Illustration: FIGURE 6.--Spring lancet, 19th century. (NMHT 321636.01; SI

photo 73-4236.)]

[Illustration: FIGURE 7.--Interior of spring lancet. (NMHT 308730.10; SI

photo 76-13535.)]

In general, German, American, and Dutch surgeons preferred the spring

lancet to the simple thumb lancet. In contrast, the French tended to

prefer the thumb lancet. Ristelhueber, a surgeon in Strasbourg, maintained

in 1819 that the simple lancet was preferable to the spring lancet both in

terms of simplicity of design and application. While allowing German

surgeons some credit for attempting to improve the spring lancet,

Ristelhueber remained firm in his view that the spring lancet was too

complicated and performed no better than the thumb lancet. The only

advantage of the spring lancet was that it could be used by those who were

ignorant of anatomy and the art of venesection. Untutored bleeders could

employ a spring lancet on those veins that stood out prominently and be

fairly confident that they could remove blood without harming other blood

vessels. The bagnio men (bath attendants), who routinely bled the bathers

in public baths, preferred the spring lancet.[69] It was more difficult to

sever a vein with a spring lancet and thereby cause serious hemorrhaging.

However, since the spring lancet was harder to clean because of its small

size and its enclosed parts, it was more likely to induce infection

(phlebitis).

While the French and British surgeons remained critical of the spring

lancet, it became popular in the United States. John Syng Dorsey, a noted

Philadelphia surgeon, wrote in 1813:

The German fleam or spring lancet I prefer greatly to the common

English lancet for phlebotomy; it is now in some parts of the United

States almost exclusively used. In a country situated like the United

States, where every surgeon, except those residing in our largest

cities, is compelled to be his own cutler, at least so far as to keep

his instruments in order, the spring-lancet has a decided preference

over the lancet; the blade of this can with great ease be sharpened

by any man of common dexterity, and if not very keen it does no

mischief, whereas a dull lancet is a most dangerous instrument; and

no one can calculate with certainty the depth to which it will

enter. To sharpen a lancet, is regarded by the cutler as one of his

nicest and most difficult jobs; it is one to which few surgeons are

competent.

The safety of using the fleam is demonstrated by daily experience;

there is no country in which venesection is more frequently performed

than in the United States, and perhaps none where fewer accidents

from the operation have occurred, of those few, I beg leave to state,

that all the aneurisms produced by bleeding, which I have seen, have

been in cases where the lancet was used. Among the advantages of the

spring-lancet economy is not the least. A country practitioner who is

constantly employing English lancets, and who is particular in using

none but the best, must necessarily consume half the emoluement

derived from the operation, in the purchase of his instruments. One

spring-lancet, with an occasional new blade, will serve him all his

life.[70]

This popularity is also reflected in various medical dictionaries of the

eighteenth and nineteenth centuries that described the instrument and in

the wide variety of spring lancets in the Smithsonian collection.

One American user of the spring lancet, J. E. Snodgrass of Baltimore, was

inspired to compose a poem about the instrument, which appeared in the

_Baltimore Phoenix and Budget_ in 1841. He wrote:

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