[98] Karl Ernst von Baer, _Ueber die Entwickelungsgeschichte der

Thiere_, Königsberg, 1828-37.

With the second half of the seventeenth century and during a large part

of the eighteenth the biological works of Aristotle attracted less

attention. The battle against the Aristotelian physics had been fought

and won, but with them the biological works of Aristotle unjustly

passed into the shadow that overhung all the idols of the Middle Ages.

The rediscovery of the Aristotelian biology is a modern thing. The

collection of the vast wealth of living forms absorbed the energies

of the generations of naturalists from Ray (1627-1705) and Willoughby

(1635-72) to Réaumur (1683-1757) and Linnaeus (1707-1778) and beyond to

the nineteenth century. The magnitude and fascination of the work seems

almost to have excluded general ideas. With the end of this period

and the advent of a more philosophical type of naturalist, such as

Cuvier (1769-1832) and members of the Saint-Hilaire family, Aristotle

came again to his own. Since the dawn of the nineteenth century,

and since naturalists have been in a position to verify the work of

Aristotle, his reputation as a naturalist has continuously risen.

Johannes Müller (1801-58), Richard Owen (1804-92), George Henry Lewes

(1817-78), William Ogle (1827-1912) are a few of the long line of those

who have derived direct inspiration from his biological work. With

improved modern methods of investigation the problems of generation

have absorbed a large amount of biological attention, and interest

has become specially concentrated on Aristotle’s work on that topic

which is perhaps, at the moment, more widely read than any biological

treatise, ancient or modern, except the works of Darwin. That great

naturalist wrote to Ogle in 1882: ‘From quotations I had seen I had a

high notion of Aristotle’s merits, but I had not the most remote notion

what a wonderful man he was. Linnaeus and Cuvier have been my two gods,

though in very different ways, but they were mere schoolboys to old

Aristotle.’

GREEK MEDICINE

Ἡρόφιλος δὲ ᾝἐν τῷ Διαιτητικῷ καὶ σοφίαν φησὶν ἀνεπίδεικτον καὶ τέχνην

ἄδηλον καὶ ἰσχὺν ἀναγώνιστον καὶ πλοῦτον ἀχρεῖον καὶ λόγον ἀδύνατον,

ὑγιείας ἀπούσης.

Herophilus, a Greek philosopher and physician (_c._ 300 B. C.), has

truly written ‘that Science and Art have equally nothing to show,

that Strength is incapable of effort, Wealth useless, and Eloquence

powerless if Health be wanting’.[99] All peoples therefore have had

their methods of treating those departures from health that we call

disease, and among peoples of higher culture such methods have been

reduced in most cases to something resembling a system. In antiquity,

as now, a variety of such systems were in vogue, and those nations who

practised the art of writing from an early date have left considerable

records of their medical methods and doctrines. We may thus form a

fairly good idea of the medical principles of the Mesopotamian, the

Egyptian, the Iranian, the Indian, and the Chinese civilizations. Much

in these systems, as in the medical procedure of more primitive tribes,

was based upon some theory of disease which fitted in with a larger

theory of the nature of evil. Of these theories the commonest was and

is the demonic, the view that regards deviation from the normal state

of health as due either to the attacks of supernatural beings or to

their actual entry into the body of the sufferer. A medical system

based on such a view is susceptible of great elaboration in a higher

civilization, but not being founded on observation is hardly capable of

indefinite development, for a point must ultimately be reached at which

the mind recoils from complex conclusions far remote from observed

phenomena. The medicine of the ancient and settled civilization of such

a people as the Assyro-Babylonians, for instance, of which substantial

traces have been recovered, is hardly, if at all, more effective,

though far more systematized, than that of many a wild and unlettered

tribe that may be observed to-day. Of such medicine as this we may give

an account, but we can hardly write a _history_. We cannot establish

those elements of continuity and of development from which alone

history can be constructed.

[99] The works of Herophilus are lost. This fine passage has been

preserved for us by Sextus Empiricus, a third century physician, in

his πρὸς τοὺς μαθηματικοὺς ἀντιρῥητικοί, which is in essence an attack

on all positive philosophy. It is an entertaining fact that we should

have to go to such a work for remains of the greatest anatomist of

antiquity. The passage is in the section directed against ethical

writers, xi. 50.

It is the distinction of the Greeks alone among the nations of

antiquity that they practised a system of medicine based not on theory

but on observation accumulated systematically as time went on. The

claim can be made for the Greeks that some at least among them were

deflected by no theory, were deceived by no theurgy, were hampered by

no tradition in their search for the facts of disease and in their

attempts at interpreting its phenomena. Only the Greeks among the

ancients could look on their healers as _physicians_ (= naturalists,

φύσις = nature), and that word itself stands as a lasting reminder of

their achievement.[100]

[100] The word φυσικός, though it passed over into Latin (Cicero) with

the meaning _naturalist_, acquired the connotation of _sorcerer_ among

the later Greek writers. Perhaps the word _physicianus_ was introduced

to make a distinction from the charm-mongering _physicus_. In later

Latin _physicus_ and _medicus_ are almost always interchangeable.

At a certain stage in the history of the Western world—the exact point

in time may be disputed but the event is admitted by all—men turned

to explore the treasures of the ancient wisdom and the whole mass of

Greek medical learning was gradually laid before the student. That

mass contained much dross, material that survived from early as from

late Greek times which was hardly, if at all, superior to the debased

compositions that circulated in the name of medicine in the middle

centuries. But the recovered Greek medical writings also contained some

material of the purest and most scientific type, and that material and

the spirit in which it was written, form the debt of modern medicine to

antiquity.

It is a debt the value of which cannot be exaggerated. The physicians

of the revival of learning, and for long after, doubtless pinned their

faith too much to the written word of their Greek forbears and sought

to imprison the free spirit of Hippocrates and Galen in the rigid

wall of their own rediscovered texts. The great medical pioneers of

a somewhat later age, enraged by this attempt, the real nature of

which was largely hidden from them, not infrequently revolted and

rightly revolted against the bondage to the Greeks in which they had

been brought up. Yet it is sure that these modern discoverers were

the true inheritors of the Greeks. Without Herophilus we should have

had no Harvey and the rise of physiology might have been delayed for

centuries; had Galen’s works not survived, Vesalius would never have

reconstructed Anatomy, and Surgery too might have stayed behind with

her laggard sister, Medicine; the Hippocratic collection was the

necessary and acknowledged basis for the work of the greatest of modern

clinical observers, Thomas Sydenham, and the teaching of Hippocrates

and of his school is the substantial basis of instruction in the wards

of a modern hospital. In the pages which follow we propose therefore

to review the general character of medical knowledge in the best Greek

period and to consider briefly how much of that great heritage remained

accessible to the earlier modern physicians. The reader will thus be

able to form some estimate of the degree to which the legacy has been

passed on to our own times.

It is evident that among such a group of peoples as the Greeks,

varying in state of civilization, in mental power, in geographical

and economic position and in general outlook, the practice of medicine

can have been by no means uniform. Without any method of centralizing

medical education and standardizing teaching there was a great variety

of doctrines and of practice in vogue among them, and much of this

was on a low level of folk custom. Such lower grade material of Greek

origin has come down to us in abundance, though much of it, curiously

enough, from a later time. But the overwhelming mass of earlier Greek

medical literature sets forth for us a pure scientific effort to

observe and to classify disease, to make generalizations from carefully

collected data, to explain the origin of disease on rational grounds,

and to apply remedies, when possible, on a reasoned basis. We may thus

rest fairly well assured that, despite serious and irreparable losses,

we are still in possession of some of the very finest products of the

Greek medical intellect.

There is ample evidence that the Greeks inherited, in common with many

other peoples of Mediterranean and Asiatic origin, a whole system of

magical or at least non-rational pharmacy and medicine from a remoter

ancestry. Striking parallels can be drawn between these folk elements

among the Greeks and the medical systems of the early Romans, as well

as with the medicine of the Indian Vedas, of the ancient Egyptians, and

of the earliest European barbarian writings. It is thus reasonable to

suppose that these elements, when they appear in later Greek writings,

represent more primitive folk elements working up, under the influence

of social disintegration and consequent mental deterioration, through

the upper strata of the literate Greek world. But with these elements,

intensely interesting to the anthropologist, the psychologist, the

ethnologist, and to the historian of religion, we are not here greatly

concerned. Important as they are, they constitute no part of the

special claim of the Greek people to distinction, but rather aid us in

uniting the Greek mentality with that of other kindred peoples. Here we

shall rather discuss the course of Greek scientific medicine proper,

the type of medical doctrine and practice, capable of development

in the proper sense of the word, that forms the basis of our modern

system. We are concerned, in fact, with the earliest evolutionary

medicine.

We need hardly discuss the first origins of Greek Medicine. The

material is scanty and the conclusions somewhat doubtful and

perhaps premature, for the discovery of a considerable fragment of

the historical work of Menon, a pupil of Aristotle, containing a

description of the views of some of the precursors of the Hippocratic

school, renews a hope that more extended investigation may yield

further information as to the sources and nature of the earliest Greek

medical writings.[101] The study of Mesopotamian star-lore has linked

it up with early Greek astronomical science. The efforts of cuneiform

scholars have not, however, been equally successful for medicine, and

on the whole the general tendency of modern research is to give less

weight to Mesopotamian and more to Egyptian sources than had previously

been admitted; thus, as an instance, some prescriptions in the Ebers

papyrus of the eighteenth dynasty (about the sixteenth century B. C.)

discovered at Thebes in 1872 resemble certain formulae in the Corpus

Hippocraticum. A number of drugs, too, habitually used by the Greeks,

such as _Andropogon_, _Cardamoms_, and _Sesame orientalis_, are of

Indian origin. There are also the Minoan cultures to be considered,

and our knowledge is not yet sufficient to speak of the heritage that

Greek medicine may or may not have derived from that source, though

it seems not improbable that Greek hygiene may here owe a debt.[102]

Omitting, therefore, this early epoch, we pass direct to the later

period, between the sixth and fourth centuries, from which documents

have actually come down to us.

[101] This fragment has been published in vol. iii, part 1, of the

_Supplementum Aristotelicum_ by H. Diels as _Anonymi Londinensis ex

Aristotelis Iatricis Menonis et Aliis Medicis Eclogae_, Berlin, 1893.

See also H. Bekh and F. Spät, _Anonymus Londinensis, Auszüge eines

Unbekannten aus Aristoteles-Menons Handbuch der Medizin_, Berlin, 1896.

[102] It is tempting, also, to connect the Asclepian snake cult with

the prominence of the serpent in Minoan religion.

The earliest medical school of which we have definite information is

that of Cnidus, a Lacedaemonian colony in Asiatic Doris. Its origin may

perhaps reach back to the seventh century B. C. We have actual records

that the teachers of Cnidus were accustomed to collect systematically

the phenomena of disease, of which they had produced a very complex

classification, and we probably possess also several of their actual

works. The physicians of Cos, their only contemporary critics whose

writings have survived, considered that the Cnidian physicians paid

too much attention to the actual sensations of the patient and to

the physical signs of the disease. The most important of the Cnidian

doctrines were drawn up in a series of _Sentences_ or Aphorisms, and

these, it appears, inculcated a treatment along Egyptian lines of the

symptom or at most the disease, rather than the patient, a statement

borne out by the contents of the gynaecological works of probable

Cnidian origin included in the so-called ‘Hippocratic Collection’.

A few names of Cnidian physicians have, moreover, come down to us

with titles of their works, and a later statement that they practised

anatomy. There can be little doubt too that the Cnidian school drew

also on Persian and Indian Medicine.

The origin of the school of the neighbouring island of Cos was a little

later than that of Cnidus and probably dates from the sixth century

B. C. Of the Coan school, or at least of the general tendencies that

it represented, we have a magnificent and copious literary monument

in the Corpus Hippocraticum, a collection which was probably put

together in the early part of the third century B. C. by a commission

of Alexandrian scholars at the order of the book-loving Ptolemy Soter

(reigned 323-285 B. C.). The elements of which this collection is

composed are of varying dates from the sixth to the fourth century B.

C., and of varying value and origin, but they mainly represent the

point of view of physicians of the eastern part of the Greek world in

the fifth and fourth centuries.

The most obvious feature, the outstanding element that at once

strikes the modern observer in these ‘Coan’ writings, is the enormous

emphasis laid on the actual course of disease. ‘It appears to me a

most excellent thing’, so opens one of the greatest of the Hippocratic

works, ‘for a physician to cultivate _pronoia_.[103] Foreknowing

and foretelling in the presence of the sick the past, present, and

future (of their symptoms) and explaining all that the patients are

neglecting, he would be believed to understand their condition, so that

men would have confidence to entrust themselves to his care.... Thus he

would win just respect and be a good physician. By an earlier forecast

in each case he would be more able to tend those aright who have a

chance of surviving, and by foreseeing and stating who will die, and

who will survive, he will escape blame....’[104]

[103] This word _pronoia_, as Galen explains (εἰς τὸ Ἱπποκράτους

προγνωστικόν, K. xviii, B. p. 10), is not used in the philosophic

sense, as when we ask whether the universe was made by chance or by

_pronoia_, nor is it used quite in the modern sense of _prognosis_,

though it includes that too. _Pronoia_ in Hippocrates means knowing

things about a patient before you are told them. See E. T. Withington,

‘Some Greek medical terms with reference to Luke and Liddell and

Scott,’ _Proceedings of the Royal Society of Medicine_ (_Section of the

History of Medicine_), xiii, p. 124, London, 1920.

[104] _Prognostics_ 1.

Just as the Cnidians by dividing up diseases according to symptoms

over-emphasized diagnosis and over-elaborated treatment, so the Coans

laid very great force on prognosis and adopted therefore a largely

expectant attitude towards diseases. Both Cnidian and Coan physicians

were held together by a common bond which was, historically if not

actually, related to temple worship. Physicians leagued together in the

name of a god, as were the Asclepiadae, might escape, and did escape,

the baser theurgic elements of temple medicine. Of these they were as

devoid as a modern Catholic physician might be expected to be free from

the absurdities of Lourdes. But the extreme cult of prognosis among

the Coans may not improbably be traced back to the medical lore of the

temple soothsayers whose divine omens were replaced by indications of

a physical nature in the patient himself.[105] We are tempted too to

link it with that process of astronomical and astrological prognosis

practised in the Mesopotamian civilizations from which Ionia imitated

and derived so much. Religion had thus the same relation to medicine

that it would have with a modern ‘religious’ medical man as suggesting

the motive and determining the general direction of his practice though

without influence on the details and method.

[105] There is a discussion of the relation of the Asclepiadae to

temple practice in an article by E. T. Withington, ‘The Asclepiadae

and the Priest of Asclepius,’ in _Studies in the History and Method of

Science_, edited by Charles Singer, vol. ii, Oxford, 1921.

During the development of the Coan medical school along these lines in

the sixth and fifth centuries, there was going on a most remarkable

movement at the very other extreme of the Greek world. Into the course

and general importance of Sicilian philosophy it is not our place to

enter, but that extraordinary movement was not without its repercussion

on medical theory and practice. Very important in this direction was

Empedocles of Agrigentum (_c._ 500-_c._ 430 B. C.). His view that the

blood is the seat of the ‘innate heat’, ἔμφυτον θερμόν, he took from

folk belief—‘the blood is the life’—and this innate heat he closely

identified with soul. More profitable was his doctrine that breathing

takes place not only through what are now known as the respiratory

passages but also through the pores of the skin. His teaching led to a

belief in the heart as the centre of the vascular system and the chief

organ of the ‘pneuma’ which was distributed by the blood vessels. This

pneuma was equivalent to both soul and life, but it was something more.

It was identified with air and breath, and the pneuma could be seen

to rise as shimmering steam from the shed blood of the sacrificial

victim—for was not the blood its natural home? There was a pneuma, too,

that interpenetrated the universe around us and gave it those qualities

of life that it was felt to possess. Anaximenes (_c._ 610-_c._ 545

B. C.), an Ionian predecessor of Empedocles, may be said to have

defined for us these functions of the pneuma; οῖον ἡ ψυχὴ ἡ ἡμετέρα

ἀὴρ οῧσα συγκρατεί ἡμᾶς, ὅλον τὸν κόσμον πνεῦμα καὶ ἀὴρ περιέχει ‘As

our soul, being air, sustains us, so pneuma and air pervade the whole

universe’;[106] but it is the speculation of Empedocles himself that

came to be regarded as the basis of the Pneumatic School in Medicine

which had later very important developments.

[106] The works of Anaximenes are lost. This phrase of his, however, is

preserved by the later writer Aetios.

Another early member of the Western school who made important

contributions to medical doctrine—in which relation alone we need

consider him—was Pythagoras of Samos (_c._ 580-_c._ 490 B. C.). For

him number, as the purest conception, formed the basis of philosophy.

Unity was the symbol of perfection and corresponded to God Himself. The

material universe was represented by 2, and was divided by the number

12, whence we have 3 worlds and 4 spheres. These in turn, according

at least to the later Pythagoreans, give rise to the four elements,

earth, air, fire, and water—a primary doctrine of medicine and of

science derived perhaps from ancient Egypt and surviving for more than

two millennia. The Pythagoreans taught, too, of the existence of an

animal soul, an emanation of the soul of the universe. In all this we

may distinguish the germ of that doctrine of the relation of man and

universe, microcosm and macrocosm, which, suppressed as irrelevant in

the Hippocratic works, reappears in the Platonic and especially in

the Neoplatonic writings, and forms a very important dogma in later

medicine.

A pupil of Pythagoras and an older contemporary of Empedocles was

Alcmaeon of Croton (_c._ 500 B. C.), who began to construct a positive

basis for medical science by the practice of dissection of animals, and

discovered the optic nerves and the Eustachian tubes. He even extended

his researches to Embryology, describing the head of the foetus as the

first part to be developed—a justifiable deduction from appearances.

Alcmaeon introduced also the doctrine that health depends on harmony,

disease on discord of the elements within the body. Curiosity as to the

distribution of the vessels was excited by Empedocles and Alcmaeon and

led to further dissection, and Alcmaeon’s pupils Acron (_c._ 480 B. C.)

and Pausanias (_c._ 480 B. C.), and the later Philistion of Lokri,[107]

the contemporary of Plato, all made anatomical investigations.

[107] For the work of these physicians see especially M. Wellmann,

_Fragmentsammlung der griechischen Aerzte_, Bd. I, Berlin, 1901.

The views of Empedocles, and especially his doctrine that regarded

the heart as the main site of the pneuma, though rejected by the Coan

school as a whole, were not without influence on Ionia. Diogenes

of Apollonia, the philosopher of pneumatism, a late fifth century

writer who must have been contemporary with Hippocrates the Great,

himself made an investigation of the blood vessels; and the influence

of the same school may be traced in a little work περὶ καρδίης, _On

the heart_, which is the best anatomical treatise of the Hippocratic

Collection. This work describes the aorta and the pulmonary artery as

well as the three valves at the root of each of the great vessels,

and it speaks of experiments to test their validity. It treats of the

pericardium and of the pericardial fluid and perhaps of the musculi

papillares, and contrasts the thickness of the walls of right and left

ventricles. The author considers that the left ventricle is empty of

blood—as indeed it is after death—and is the source of the innate heat

and of the absolute intelligence. These views fit in with the doctrines

of Empedocles, so that we may perhaps even venture to regard this work

as a surviving document of the Sicilian school. It is interesting to

observe that we have here the first hint of human dissection, for the

author tells us that the hearts of animals may be compared to that

of man. The distinction of having been the first to write on human

anatomy, as such, belongs however, probably to a later writer, Diocles,

son of Archidamus of Carystus, who lived in the fourth century B.

C.[108]

[108] Galen, περὶ ἀνατομικῶν ἐγχειρήσεων, _On anatomical preparations_,

§ 1, K. II, p. 282.

We may now turn to the Hippocratic Corpus as a whole. This collection

consists of about 60 or 70 separate works, written at various periods

and in various states of preservation. At best only a very small

proportion of them can be attributed to Hippocrates, but the discussion

of the general question of the ‘genuineness’ of the works is now

admitted to be futile, for it is certain that we have no criteria

whatever to determine whether or no a particular work be from the pen

of the Father of Medicine, and the most we can ever say of such a

treatise is that it appears to be of his school and in his spirit. Yet

among the great gifts of this collection to our time and to all time

are two which stand out above all others, the picture of a man, and the

picture of a method.

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