SIR,

I have carefully perused the case you have communicated to me, and am

of opinion, that the disease you have described was not the small-pox.

The cold fit which preceded the other complaints, is what usually

happens at the commencement of the small-pox in common with other

fevers; with this exception, I do not find one symptom during the

whole illness, that corresponds with the well known progress of that

disease.

The eruptions (on which I presume the suspicion of the small-pox was

founded) differed from that distemper in every essential point, viz.

The time and manner of their appearance; the parts they occupied; and

their form and progress. Neither am I of opinion that the disease was

the effect of any variolous matter left in the blood, in consequence of

the previous inoculation.

That the natural and inoculated small-pox, as well as other diseases

which form critical discharges on the skin, may sometimes be succeeded

by boils or breakings out, is well known; but these follow very soon,

are free from danger, and easily cured by gentle purges. Now in the

case before me, I find the patient passed through the inoculated

disease, in a regular, complete, and satisfactory manner, and continued

well for six weeks after, making no complaint: after which he was

seized with a disease that I have not the least doubt was a fever

of the putrid kind; but I do not think that the pustulary eruptions

can with propriety be deemed critical, as they did not terminate the

disease; I rather esteem them to have been marks or tokens of great

malignity and danger.

In the course of my whole practice, which it is well known has been

extensive, I never knew a single instance of any one having the natural

small-pox, after having been inoculated; nor have I ever known any

person to have the disease a second time in the natural way.

I shall not pretend to decide on what may have happened to others; but

what I have said is true, so far as relates to my own experience.

The report of the gentlemen who opened the body, affords no material

information.

The appearance of the spots, is such as might be reasonably expected on

any person who died of a malignant fever. Dry scabs frequently remain

on the inoculated parts, for some months after the disease.

The Present Method of Inoculating for the Small-Pox To which are added, some experiments, instituted with a view to discover the effects of a similar treatment in the natural small-pox · 第 52 / 57 题