Dec. 5th.] A healthy man of 38 was inoculated. On the 7th he called
on me, when his arm itched very much, and shewed certain marks of the
infection having succeeded.
The inflammatory appearance was then considerably abated, and the
incisions seemed disposed to heal. He felt no uneasiness on the part,
nor had he any illness.
On the 12th and 13th he complained of pains in his head and limbs,
as also of stiffness under his arms, which I esteem one of the most
certain proofs of the infection having taken place. There was no
alteration in the pulse, nor any other sign of a fever; a few pimples
about the neck and arms followed these complaints, yet not such as I
should have esteemed variolous on any other occasion: for some soon
disappeared; and others, which remained long enough to have a little
matter formed in them, proceeded to this state with great irregularity.
He was inoculated again, but without the least effect.