COMPETENCE FOR MARRIAGE OF WOMEN SUFFERING FROM DISEASE.

In this section we must consider the competence for marriage of women

suffering from heart disease, of those suffering from hereditary

tendency to mental disorders and neurasthenic states, and, finally, of

those affected with tuberculosis.

Every doctor is confronted during the practice of his profession by the

problem whether a young woman known to suffer from heart disease is

justified in entering upon marriage and in exposing herself to the

dangers entailed on her diseased heart by copulation, pregnancy,

parturition, and the puerperium. The solution of this problem is as

important as it is difficult. On the one hand, it determines the whole

future course of a human life which is still ascending the upward path

of its vital career, and a negative decision often annuls in a moment

the young woman’s ideals and hopes; on the other hand, an affirmative

decision involves the responsibility for the consequences of marriage,

often grave in these cases.

The consequences are in fact apt to be very serious indeed. The normal

act of intercourse, in a young and sensitive woman, has already an

exciting influence on the nerve apparatus by which the movements of the

heart are controlled. The frequency of the heart’s action is greatly

increased, the cardiac impulse becomes much stronger, there is marked

pulsation of the peripheral arteries, the conjunctiva is injected, the

respiration more frequent. These manifestations, which normally are

quite transient, attain a greater intensity and exhibit a longer

duration in persons affected with heart disease. In some instances,

violent tachycardial paroxysms occur, with considerable dyspnœa, pains

in the cardiac region, headache, and even syncopal attacks.

Pregnancy, in consequence of the extensive changes undergone not only by

the reproductive apparatus but also by the general system, and further

in consequence of the vital needs of the developing embryo, involves

extensive claims upon the cardiac activity. It is easy to understand

that the diseased heart must be taxed more severely than the healthy

heart by the extension of existing vascular areas, the addition of new

vascular areas, and the increase in the quantity of the blood, during

pregnancy; and it is not surprising if the overtaxed organ threatens

sometimes to give way under the strain. Thus, during pregnancy in women

affected with morbus cordis, we observe numerous troubles in the way of

disturbances of cardiac activity and passive congestion of various

organs, culminating at times in abortion.

Parturition and the puerperium, moreover, bring several factors into

play which tend to affect unfavorably even a heart that is quite normal;

and in cases in which there is disease either of the heart or of the

great vessels, these factors may lead to the occurrence of most alarming

symptoms. In this connection we may refer to endocarditis, to fatty

degeneration of the myocardium, and to the rupture of atheromatous

arteries.

From the time of _Galen_ onwards all medical writers have agreed that

the heart is unfavorably influenced by pregnancy and its

consequences—but from this incontestable proposition to deduce the

general conclusion that young women affected with heart disease must be

forbidden to marry is in my opinion too great a jump, and altogether too

sweeping a statement. The apophthegm of _Peters_, an author to whom we

are certainly indebted for some of our knowledge of the _accidents

gravido-cardiaques_, that in the case of women suffering from morbus

cordis the rule must be enforced, _fille pas de mariage_, _femme pas de

grossesse_, _mère pas d’allaitement_, has a fine air of apodictic

brevity, but is entirely devoid of justification. No such rigid

prohibition is advanced by recent writers on heart disease, such as

_Huchard_, _von Leyden_, and _Rosenbach_; not, at least, without

qualifications.

The question as to the permissibility of marriage to girls and women

affected with heart disease cannot, in fact, be answered by any general

proposition; and each case demands separate inquiry and a careful

balancing of individual considerations. I have known cases in which the

marriage of young girls suffering from morbus cordis was equivalent to a

sentence of death, the execution of which was delayed for a few months

only. On the other hand, I have known many women belonging to the upper

classes and suffering from cardiac defects to pass through numerous

pregnancies and to give birth to a number of children with no more than

trifling disturbances of compensation. I am acquainted with a lady who

when a young girl was urgently advised against marriage, on account of

extensive aortic valvular incompetency, by two celebrated physicians.

The advice was disregarded, and this lady is now the mother of four

children, the eldest of whom is twenty-two years of age, and her general

condition is in no way worse than it was before her marriage. The

dangers of marriage in women suffering from morbus cordis are in my

opinion generally overrated.

The degree to which a woman affected with heart disease will be injured

by married life, will depend on the nature of the cardiac affection, on

the time it has already existed, on the adequacy of compensation or the

intensity of existing disturbances of compensation, on the general state

of nutrition of the patient, on the more or less favorable social

position, and on the manner in which sexual intercourse is regulated.

My own opinions in respect of this question may be summed up as follows:

A woman who has comparatively recently (within a few years) acquired a

valvular defect, and in whom the disease has run such a course that, in

consequence of dilatation of certain chambers of the heart and of

hypertrophy of those segments of the myocardium on which increased work

has been thrown, and thus in consequence of adaptation of the

cardio-vascular apparatus to the new conditions, the circulation and

distribution of the blood take place in a manner closely resembling that

in which these functions are effected in a normal, healthy individual—in

a word, a woman in whom the valvular disease appears to be adequately

compensated,—if, in addition, the patient is well nourished, if the

hæmatopoietic function has not undergone any notable disturbance, if the

muscular system is powerful and the nervous system possesses sufficient

power of resistance—then marriage may be permitted without hesitation.

In the case of such a girl or woman, we can confidently assume that the

adequate compensation of the valvular disease will enable the heart to

meet with success the claims made upon its reserve energies by sexual

intercourse, by pregnancy, and by parturition, and that these processes

will not involve any excessive danger to life.

A woman with valvular heart disease, even when that disease is well

compensated, will indeed during pregnancy and still more during

parturition and the early days of the puerperium, be liable to suffer

from various manifestations of cardiac disorder. The action of her heart

will be subject to paroxysmal increase in frequency and force, sometimes

also there may be transient attacks of cardiac asthenia; at the same

time the breathing will become more frequent and deeper, and

occasionally, even, there may be severe dyspnœa. Perhaps also symptoms

of venous congestion may manifest themselves, digestive disturbances,

sense of pressure in the head, swelling of the feet, œdema of the

abdominal wall, even slight albuminuria. Just after childbirth,

moreover, an abnormally intense depression of the circulation with

infrequency of the heart’s action will be liable to ensue. In the great

majority of cases, however, in which the conditions detailed above are

fulfilled, the disturbances of compensation occasioned by pregnancy and

the puerperal state will not seriously threaten life; and as soon as the

puerperal period has been safely passed through, the heart will again be

competent for its duties and will do its work as well as before.

These statements apply, not only to cases of well-compensated valvular

disease, especially mitral insufficiency, mitral stenosis, and aortic

insufficiency, but also to cases in which the heart has made a good

recovery after an attack of pericarditis, and to cases of moderately

extensive disease of the myocardium consequent on acute articular

rheumatism or the acute infections.

As indispensable conditions for such a favorable prognosis, we naturally

assume that the pregnant woman is in a position to command the extreme

bodily care that in her condition is doubly needful, that she is able to

avoid all severe physical exertion, and that she will be subjected to

continuous medical supervision in respect of the adoption of suitable

dietetic and hygienic measures.

Such a favorable prospect as regards marriage in cases of

well-compensated heart disease will, however, be clouded in the case of

women who are either very anæmic or predisposed to nervous disorders;

nor is the prognosis favorable as regards women in whom the heart

disease is either congenital, or acquired in early youth, or as regards

women contemplating marriage when already well up in years.

For in very anæmic women, even when the heart is quite sound, frequently

recurring attacks of tachycardia often occur during pregnancy, in the

absence of any obvious exciting cause; œdema of the lower extremities,

and the formation of extensive varices, are also common. Increased

nervous reflex irritability has also an unfavorable influence upon

cardiac innervation. In cases, again, in which the heart disease is of

long standing, the functional capacity of the heart is so notably

depressed that the organ is likely to prove incompetent to meet the

increased demands made upon it by the processes of pregnancy. Finally,

in elderly women, superadded to the valvular defects, we have the

dangers dependent upon the already beginning arteriosclerotic changes in

the bloodvessels. In all such cases, therefore, it will be the duty of

the physician to advise his patient not to marry; and in any case to

impress upon her mind the extreme probability, amounting almost to

certainty, of serious aggravation of the heart disease by marriage, with

permanent impairment of the general health.

In cases of valvular disease accompanied by serious disturbances of

compensation, and in cases of notable degeneration of the myocardium in

which pronounced symptoms of cardiac muscular insufficiency have made

their appearance, marriage must be absolutely forbidden, as directly

imperilling life. When even moderate bodily exertion suffices to cause

palpitation, increased frequency of the pulse, and shortness of breath,

when extensive œdema of the lower extremities is present and fails to

disappear even after the patient has been strictly confined to bed, when

the pulse very readily becomes irregular both in rhythm and force,

whilst the urine is often scanty and contains variable quantities of

albumin, when conditions of cardiac asthenia readily arise,

characterized by a small, irregular pulse, coldness of the extremities,

cyanotic tint, nausea, respiratory need,[42] and syncopal attacks—in all

such cases, whether the symptoms just described are dependent upon

valvular defects, upon pathological changes in the arteries, or upon

diseases of the myocardium, in all alike the occurrence of pregnancy is

a true disaster, which in the vast majority of cases causes a great and

enduring aggravation of the disease, and frequently enough costs the

patient her life.

Even in such cases as were previously described, in which, the heart

disease not being severe, the patient was told that marriage was

permissible, it is the duty of the physician to lay down certain rigid

rules regarding sexual activity.

Women suffering from heart disease should not have sexual intercourse

frequently, because, if the peripheral nervous stimulation of the

genital organs is excessive in consequence of too frequent acts of

coitus, cardiac activity is likely to be influenced powerfully in a

reflex manner, leading to the occurrence of attacks of cardiac asthenia.

Again, sexual intercourse must always be effected in such a manner that

the act attains its physiological conclusion, and that in the woman as

well as in the man the orgasm has its normal outcome, that is to say

that at the conclusion of the act the woman’s cervical glands are

evacuated with the accompaniment of the sense of ejaculation. The

_congressus interruptus_, which precisely in these cases in which the

wife suffers from heart disease is so frequently practiced by the

husband with a view to preventing conception, must be strictly

forbidden, since this mode of intercourse tends to give rise to various

forms of reflex cardiac disturbance, most commonly to paroxysms in which

the cardiac action becomes unduly frequent, in association with

diminution of vascular tone, vasomotor disturbances, and states of

mental depression; and where organic heart disease already exists, these

reflex functional disturbances involve various dangers.

The physician is further justified in advising that a woman with organic

heart disease should not give birth to more than one or two children.

This advice is the more needful for the reason that with each successive

pregnancy the functional capacity of the woman’s diseased heart

diminishes according to a geometrical ratio, and to a corresponding

degree the danger to life increases. These are cases in which in my

opinion it is the physician’s duty to concern himself with the

subject—in general so equivocal—of the use of preventive measures, and,

having regard for the preservation of a woman’s life, and uninfluenced

by any false delicacy, but with moral earnestness, to inform his patient

with respect to the needful prophylactic measures. The artificial

termination of pregnancy, which unquestionably is often justified in

women suffering from heart disease, but which unfortunately is apt to

have very unfavorable results, will rarely need to be discussed if by

the proper employment of preventive measures care is taken that

pregnancy does not recur too frequently.

To enable us to answer the question whether, in the case of neurasthenic

and hysterical young women, and in those hereditarily predisposed to the

occurrence of mental disorders, the physician shall advise for or

against marriage, attention must in the first instance be directed to

the established facts relating to the favorable or unfavorable

influence, as the case may be, of sexual intercourse and its

consequences (pregnancy and childbirth) upon existing nervous disorders

and upon the predisposition to their occurrence.

Without regarding as fully justified the opinion that in the female sex

sexual abstinence has in all circumstances an unfavorable influence upon

the nervous system or even that such abstinence is to be regarded as the

principal cause of nervous and hysterical troubles, we must consider it

fully proved that in a number of the commonest varieties of nervous

disease occurring in neurasthenically predisposed subjects, such as

neurasthenia, hysteria and neurosis of anxiety[43], the lack of sexual

satisfaction aggravates these troubles, whilst suitably regulated sexual

intercourse has an actively beneficial effect. Not, indeed, that it is

an infallible means, but none the less the effects are often striking,

as I have frequently had occasion to observe, both in young women so

affected entering upon marriage for the first time, and also in young

widows who have remarried. Especially is this true of women in whom the

sexual impulse is exceedingly powerful, and even pathologically

increased to the extent of marked sexual hyperæsthesia; likewise also in

women whose social circumstances and manner of life induce increased

sexual appetite. Be it understood, I refer here to regular and moderate

sexual intercourse, and not to sexual excesses, which latter, by

inducing nervous exhaustion, may have a distinctly deleterious effect.

In many cases, however, we observe in women suffering from sexual

neurasthenia, that sexual intercourse, even when practiced at long

intervals, gives rise to nervous prostration with deep emotional

depression and long-lasting aggravation of the existing nervous

disorder. This statement applies with especial force to very hysterical

epileptic girls with hereditary predisposition to mental disorder.

From the fact that among persons hereditarily predisposed to mental

disorder, the unmarried are on the average more often affected with

insanity than the married, the inference has been drawn that marriage

may be recommended to such persons as a measure likely to counteract

their hereditary tendency to insanity. The argument, however, lacks

validity, more especially as regards women; among whom, moreover, from

the age of sixteen to the age of thirty, insanity is proportionately

more prevalent among the married, though above the age of thirty it is

more prevalent among the unmarried.

In the great majority of neurasthenic women, normal sexual intercourse,

practiced in moderation, has, according to _Löwenfeld_, no deleterious

effect; often, indeed, as a consequence of unaccustomed abstinence, an

aggravation of existing nervous troubles may be observed. But, as this

author maintains, nervous exhaustion may result in the complete

disappearance of the orgasm during sexual intercourse, or in great

difficulty in its production; this circumstance suffices for the most

part to explain the fact that in women suffering from great depression

of the nervous functions, the fulfilment of their sexual duties has

sometimes an unfavorable influence on their general condition. As

regards hysteria, it cannot be denied, that in many hysterical women

marriage results in a favorable change in the general condition; we

must, however, be careful not to overrate the significance of such

observations. As a rule all that actually takes place is a diminution in

the intensity or even a disappearance of certain morbid manifestations

previously present, without, however, an eradication of the hysterical

temperament.

In epileptic young women, the first experience of sexual intercourse may

precipitate a fit. Cases are indeed on record in which, in hereditarily

predisposed girls, the first coitus was the exciting cause of the first

epileptic fit, the fits recurring every time sexual intercourse was

repeated.

It is a comparatively frequent occurrence in psychopathically

predisposed girls for severe mental disturbances to make their

appearance during the honeymoon, after the first experience of sexual

intercourse; when this occurs, it is doubtless to be accounted for by

the combined influence upon the mind of all the changes in the

circumstances of life which have resulted from the marriage. In the case

of two newly married women, one of whom had well-marked hereditary

predisposition, whilst in the other there was no known family history of

mental disorder, _Löwenfeld_ observed shortly after marriage the onset

of severe melancholia, with refusal of food. The delicate, nervous

temperament of these two women, on the one hand, and, on the other,

possibly, a somewhat too eager and passionate attitude on the part of

their respective husbands, led their first experience of sexual

intercourse to result in a nervous impression of the nature of shock,

which their nervous system was too weak to resist.

Frequently recurring pregnancy and childbirth may, according to

_Krönig_, act as the predisposing cause in the production of

neurasthenia. In regard to hysteria also we must admit that the onset of

some disease of the organs of generation frequently leads previously

latent hysteria to manifest itself openly, and further we have to

recognize that diseases of the reproductive system often give the

clinical picture of hysteria a quite distinctive coloration; the

physiological course of the functions of the generative organs is also

competent to produce both of these effects. _Krönig_, however, rejects

the view that the lack of sexual intercourse has an unfavorable

influence upon the nervous system in women, and gives rise to hysterical

and neurasthenic disorders. The favorable influence which marriage is

often observed to exercise upon the course of nervous disorders is

explicable with reference to psychical considerations of a very

different nature. Sexual abuses, masturbation, and the use of preventive

measures, give rise in women far less often than in men to neurasthenic

and hysterical conditions.

_Féré_ asserts that in certain neurasthenic patients sexual intercourse

induces a general blunting of the senses, and especially of hearing and

sight. Actual amaurosis of short duration may even be observed; also

cutaneous anæsthesias, paralytic conditions of the extremities taking

the form either of hemiplegia or paraplegia, convulsive attacks, and

somnolent paroxysms.

_Delasiauve_ observed that epileptic patients, who during residence in

an asylum had remained almost entirely free from fits, after returning

home and resuming sexual intercourse, even in strict moderation,

suffered from a recrudescence of the convulsive seizures; when

intercourse was excessive, the relapse was naturally even more severe.

In two instances, in women who in a single night had practiced

intercourse to very great excess, _Hammond_ observed paralysis of both

legs to ensue; he saw also in numerous cases spinal irritation and other

nervous disturbances as a consequence of sexual excesses.

_Von Krafft-Ebing_ points out, with reference to the prophylactic

influence of marriage in respect of mental disorder, that in men early

marriage diminishes the danger of the occurrence of such disorder,

whereas in women marriage is undesirable before the attainment of

complete physical maturity.

With regard to marriage in the case of persons suffering from nervous

diseases, _Ribbing_ lays down the rule that when such diseases have been

severe and have occurred in numerous members of a family, whilst a few

only in the family have remained healthy, when, moreover, the illness

has been accustomed to make its first appearance only after the

attainment of maturity, no indications of its onset being noticeable in

childhood or youth—one belonging to a family thus afflicted should be

advised not to marry. Where, however, the hereditary tendency is to a

disease likely to manifest itself in childhood or youth, a member of

such a family who has been fortunate enough to pass through the years of

development without exhibiting any pronounced disturbance of the nervous

system, may be permitted to marry if certain precautions are observed. A

woman with a tendency to alcoholism should in no circumstances be

allowed to marry. In the cases, fortunately rare, in which the

drink-craving exists in women, marriage is even more undesirable than it

is in the case of men similarly afflicted, for the female drunkard is in

a position in which she can mishandle and neglect her children

throughout the entire day; and, moreover, this affection appears to be

even more obstinately incurable in women than it is in men.

_Löwenfeld_ very rightly insists that in deciding on the advisability of

marriage in the case of neurasthenic and hysterical girls the

anticipated influence of sexual intercourse must not be the sole

determinant. “Regulated sexual intercourse, such as is rendered possible

by marriage, has often a favorable influence on previously existing

states of nervous weakness. But we should go too far if we were to

attribute the beneficial effect of married life on such conditions

solely to sexual intercourse. This latter is but one factor among

several, the others being no less important. These others are: The

pleasures of an orderly domestic activity; the withdrawal of the

patient’s attention from her own condition, partly by domestic duties

and difficulties, and partly by the novelty of marital companionship;

the gratification, especially strong in women, at having obtained a

support in life; and, finally, the joyful expectation of motherhood.

These factors, however, are not present in every marriage. When their

presence cannot reasonably be anticipated, when, in consequence of

insufficient means, the marriage is likely to entail increasing

troubles, or when, owing to the want of suitability of temperament,

annoyances and quarrels are likely to occur, we must throw the weight of

our advice into the scale against the proposed marriage, since the

advantages of regulated sexual intercourse are not likely to outweigh

the disadvantages just detailed. Even when means are ample and the

characters of the couple contemplating marriage are unquestionably

harmonious, we must nevertheless (temporarily, at any rate) advise

against marriage, we must, that is to say, advise the postponement of

marriage, if the bride is suffering from severe hysterical or

neurasthenic states. Where, further, such neurasthenic or hysterical

troubles occur in a woman with pronounced hereditary predisposition to

nervous disease, we must, both for the sake of the possible progeny and

on account of the uncertain influence of married life on the health of

the patient, absolutely and unconditionally prohibit marriage. In cases

also in which severe hereditary predisposition to mental disorder exists

(especially when derived from both parents), and in addition stigmata of

psychopathic degeneration are actually apparent in the patient, or she

has already suffered from the development of a psychosis, we must

decisively object to the patient’s marriage.”

As regards the marriage of young women suffering from tuberculosis, we

must take into consideration a fact that medical experience has

conclusively established, namely, that the processes of generation have

an unfavorable influence upon pulmonary phthisis. Girls with an

inherited predisposition to tubercular disease, sometimes first manifest

the symptoms of pulmonary tuberculosis at the time of the menarche. In

cases of developed tuberculosis, copulation and the excitement of the

vascular system associated therewith have a more or less unfavorable

influence—and all the more inasmuch as, in accordance with the saying

_omnis phthisicus salax_, women affected with tuberculosis often exhibit

a very lively sexual impulse, an almost insatiable sexual appetite.

Sexual excesses are, moreover, very likely to lead to the occurrence of

hæmoptysis.

In former days it was believed that conception and pregnancy, when

occurring in women suffering from tuberculosis, had a restraining

influence on the progress of the pulmonary disease, a view which found

expression in the assertion of _Baumes_ and _Rosières de la Chassagne_

that of two women affected with tuberculosis to the same degree of

severity, one who became pregnant would always outlive the other who

failed to become so. Careful and sufficient observations on the part of

physicians and gynecologists have, however, shown that this view was

fallacious, and, on the contrary, that during pregnancy tuberculosis

advances with more rapid strides, that pregnancy, and lying-in

accelerate the fatal event (_Grisolle_, _Lebert_), that tuberculosis

acquired shortly before pregnancy or in the course of that condition,

progresses with exceptional rapidity (_Larcher_), and that the lying-in

period is especially perilous to these patients (_A. Hanau_). In some

cases of consumption it is the first pregnancy that is the most

perilous, but in other cases a later pregnancy proves more destructive.

_Ribbing_ goes even further, insisting that neither man nor woman

affected with pulmonary consumption should marry. “If, indeed,” he

writes, “consumptives desire to enter upon marriage, merely with the aim

of being faithful to one another and assisting one another for the short

time that remains to them, I should offer no opposition. But there must

be a complete mutual understanding of the facts of the case, and an

unalterable determination on the part of both to carry out the

resolutions made prior to marriage, for failing this the consequences

will be most disastrous. In most cases, however, the course adopted by

_Bulwer’s Pilgrims of the Rhine_ is to be preferred, the lovers

contenting themselves with the condition of a betrothed pair, and in

that state awaiting the approach of death—or, if exceptionally

fortunate, proceeding to marriage only after restoration to health.”

It would certainly appear that in the case of girls suffering from

pronounced phthisis, we are justified in advising against marriage, on

account of the great danger which this state entails of a rapid advance

in the pulmonary disease.

Based upon the observations of _Schauta_ and _Fellner_, the latter

author advances the rule that in the case of a woman suffering from

disease, marriage should be forbidden only when the mortality from the

disease in question is not less than 10 per cent. In this category we

must include severe cases only of pulmonary tuberculosis; whilst cases

of laryngeal tuberculosis will, according to this rule, be absolutely

unfitted for marriage. Among heart-affections contra-indicating

marriage, he includes mitral stenosis, other valvular affections in

which there is serious disturbance of compensation, and myocarditis; he

considers marriage inadmissible also in cases of chronic nephritis, and,

among surgical affections, in cases of malignant tumour. In cases in

which during a previous pregnancy the patient has been affected by one

of the following diseases, viz., severe chorea, mental disorders, severe

epilepsy, pulmonary tuberculosis which progressed much during the

pregnancy, morbus cordis with considerable disturbance of compensation,

severe heart trouble due to Graves’ disease—in all such cases, a

repetition of pregnancy should be avoided.

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