CHAPTER II.

SPINAL IRRITATION.

I retain this phrase, not because it is an absolutely good one, but

because it has become so familiar that it is difficult to dispense with

it. We have taken a useful step, however, in separating the true

neuralgias from the somewhat indefinite group of diseases to which this

title has been given. I think the reader who has carefully studied Part

I. of this work will not deny that the latter disorders present a very

clear and definite common outline which distinguishes them essentially

from the vaguer affections to be described under the present heading.

Spinal irritation, in my sense, includes all those conditions in which,

without any special mental affection, and without any single nerve being

definitely affected, there are sensations varying between mere cutaneous

tenderness, often of a large and irregular surface, and acute pain

approaching neuralgia in character, together with fixed tenderness of

certain vertebrae on deep pressure. A very large majority of the

phenomena are such as would be popularly included (now that they are

known not to be of an inflammatory character) under the term

"hysterical." That unhappy word crosses our path at every turn in a most

embarrassing manner, and yet it can hardly at present be said that we

could afford to do without it.

The more typical cases of so-called "hysterical hyperaesthesia" present

the following phenomena: Along with the general symptoms of the

hysterical temperament (tendency to causeless depression, variable

spirits, sensation of globus, semi-convulsive attacks terminated by the

discharge of a great quantity of pale, limpid urine) there is commonly a

marked superficial tenderness of the surface everywhere, and an

exaggeration of reflex irritability. The general tenderness is so far

merely cutaneous that deep pressure is ordinarily borne better than the

lightest finger-touch. But besides this there are usually one or several

spots in which the tenderness is more profound and genuine. There is

almost sure to be some point in the spinal column where firm pressure

not merely evokes a complaint of pain, but also induces secondary

objective phenomena connected with distant organs, such as nausea and

vomiting when the cervical vertebrae are tender, severe gastric pain when

the dorsal vertebrae are tender, etc. In such cases there is not only

spinal tenderness, but very usually also a well-marked tenderness in the

epigastrium and the left hypochondrium, the _trepied hysterique_ of

Briquet. The reader must, however, be warned that the whole of these

three tender points may be merely myalgic, and it is necessary very

carefully to observe whether local movements do or do not seriously

aggravate the pain in them. And, on the other hand, the spinal tender

point may be merely the "point apophysaire" of a true neuralgia which

exhibits no other symptoms of the so-called hysteric constitution.

The kind of hysteria that is joined with the existence of fixed tender

spots in definite points of the vertebral column is not commonly

distinguished by the occurrence of cutaneous anaesthesia; but those

writers are certainly wrong in saying that such a combination never

takes place. I have seen examples of the most marked union of the two

classes of symptoms in the same person.

These cases of so-called spinal irritation with general hysteric

manifestations are very commonly attended with paroxysmal pains that

approach true neuralgia in character. Nor is it to be denied that we

sometimes meet with the combination of general hysteria, spinal

tenderness in definite points (with secondary spasmodic or paralytic

phenomena always following pressure exerted on the latter), and true

neuralgia limited to one nerve. But the more typical spinal irritation

cases are merely complicated with a tendency to vague pains which are

shifting both in character and position, not with definite unilateral

neuralgia always haunting the same nerve and exhibiting more or less of

the same type. In fact, as far as one can judge in the absence of any

precise information as to the condition of the nervous centres in such

cases, it would seem likely that the ordinary cases of spinal irritation

differ from the true neuralgias chiefly in this--that the injury, or

inherited weakness of organization, or both, which is at the root of the

malady, is at once slighter in degree, and spread over a larger tract of

the nervous centres, than that which produces a true neuralgia. I

believe that Dr. Radcliffe is right in supposing it to be probable that

a blow or other injury to the back producing general spinal shock, is

the original but unsuspected cause of a large proportion of these cases.

One of the most perfect examples of spinal irritation that I have ever

seen (and which also contrasts keenly with the commoner hysteric

affections on the one hand, and the true neuralgiae on the other) was

that of a girl whom I examined together with Dr. Walshe, Dr. Reynolds,

and Dr. Bridge. This young lady was a most intelligent person, and not

in the slightest degree inclined to the apathy and idleness so often

seen in hysterical people. She had received what was thought at the time

to be a very slight contusion in a railway collision, in which, however,

her sister, who was in the same carriage, had been severely injured. She

nursed this sister assiduously, and it was not till three or four months

later that her own health began to fail seriously; but she then became

anaemic and extremely depressed. About six months after the accident it

was quite casually discovered that there was a spot over the lowest

cervical vertebra, pressure on which gave her exquisite pain and a

sensation of extreme nausea; and the very curious observation was made

that such pressure instantaneously produced extinction of the right

pulse, the left pulse remaining unaltered. In this case it cannot be

doubted that a serious shock had been communicated to a lateral segment

of the cord involving chiefly the vaso-motor nerve fibres, in which

probably some decided material lesion had been gradually set up; and

besides this there was probably slighter damage to the spinal cord

generally, as there was great general feebleness of movement, though no

actual paralysis of the limbs.

Along with the phenomena of fixed spinal tenderness, without distinct

neuralgia of any particular nerve, we not unfrequently observe the

development of more or less decided tenderness of some of the internal

surfaces of the body. I have recently had under my care a young woman in

whom a very tender point was developed over the second cervical

vertebra, and who suffered from such persistent tenderness of the whole

posterior part of the pharynx, that I was for some time seriously

apprehensive of the existence of spinal caries and post-pharyngeal

abscess. The general character of her symptoms, however, induced me to

hope that the case was one of spinal irritation merely, and the event

proved that this was the case, for under the use of iron and small doses

of strychnia she recovered completely in about three weeks. In another

patient who came under my care about twelve months ago, there was

extraordinary sensitiveness of the gastric mucous membrane, causing

exquisite pain after she had eaten almost any thing: there was only

occasional vomiting, however, and there had never been any haemorrhage,

so that the evidence for gastric ulcer, which I otherwise inclined to

think existed, was insufficient. I discovered that pressure on the third

or the fourth dorsal vertebra gave great pain, and produced a strong

inclination to vomit; this made it probable that the affection was

spinal, and accordingly all treatment addressed to the stomach was

abandoned. Flying blisters to the neighborhood of the painful spinal

points quickly relieved all the symptoms.

Another distressing class of symptoms, which is very commonly observed

in connection with these cases of spinal irritation, is that of abnormal

arterial pulsations: I am not sure whether even severe neuralgia

produces more distress than does this pulsation. I have repeatedly seen

abnormal pulsation of the carotids in connection with fixed

tender-points over the cervical or the upper dorsal vertebrae; and still

more commonly pulsation of the abdominal aorta in connection with

tenderness over one or two of the upper dorsal vertebrae. Spasmodic cough

and spasmodic dyspnoea frequently accompany tenderness of points in

the upper half of the spinal column; and in one instance I have seen

pressure on the lowest cervical vertebrae produce a paroxysm which looked

alarmingly like angina pectoris. A case of singularly prolonged and

obstinate spasmodic hiccough which came under my notice was

distinguished by the presence of a fixed tender spot over the third

dorsal vertebra.

Prolonged spastic contraction of voluntary muscles, going on, sometimes

for weeks, and even months, is a phenomenon that has often been

observed; it may attack the arm only, or may affect all the limbs, and

the muscles of the trunk and of the neck: it is for the most part

symmetrical, but is occasionally unilateral. It begins in the

extremities, and is very commonly limited to them; it is much more

gentle than tetanic spasm, and is also painless, or nearly so; but the

contraction is often strong enough to resist very vigorous efforts at

artificial extension.

Paralyses, both of bowel and bladder, have been recorded among the

occasional phenomena of spinal irritation with fixed tender points; but

I cannot say that I have ever seen such an occurrence. On the whole, I

must say that by far the most frequent phenomena of spinal irritation

that I have seen have been somewhat diffuse cutaneous or mucous

tenderness and irritability (without acute pain) and the presence of

tormenting arterial throbbings; also a marked tendency to aggravation of

some symptoms, especially the gastric, when firm pressure is made upon

the tender spinal points. For a further and fuller account of the

phenomena of spinal irritation I may refer the reader to the able

article of Dr. Radcliffe,[48] and the work of the brothers Griffin,

already quoted; adding the suggestion, however, that both these

authorities, and especially the Griffins, appear to me not to draw a

sufficiently clear distinction between the class of cases that I have

been attempting to describe and the true neuralgias.

After what has been said, there is no need to draw out a formal list of

the points of diagnosis between spinal irritation and neuralgia. It must

be admitted, moreover, that the two forms of diseases have a strong

connection in the fact that they are each of them most frequently

developed in the descendants of neurotic families. It is by the more

generalized character of the symptoms, and the absence of the tendency

to perpetual recurrence of paroxysmal pain in one definite nerve, that

spinal irritation is mainly distinguishable from true neuralgia. I may

add that there is a marked distinction, also, in the results of

treatment.

The treatment of spinal irritation is, it must be confessed still in an

unsatisfactory position; and I believe that a good deal of unnecessary

discouragement has been occasioned to physicians by their failures to

cure supposed neuralgias which really belonged to the spinal irritation

class. I would assuredly by no means assert that genuine neuralgia is

not frequently intractable, or even incurable; but it is certainly much

more curable than spinal irritation; and for this reason, mainly as I

believe--that there is much more possibility of aiming our remedies at

the actual seat of the disease. On the other hand, in spinal irritation

we are confused and distracted with a variety of phenomena for which

even the most subtle analysis will frequently fail to trace a common

origin. It is true that the existence of definite tender spots in the

spine apparently suggests a strictly local application of remedies; and

it true also that medication based upon this fact is sometimes very

effective; but this is, in my experience, only an occasional result, and

the practitioner who trusts to local measures will frequently be

disappointed. And, on the other hand, the general tonic treatment, and

the use of special medicines, like quinine and arsenic, or the

hypodermic injection of morphia oratropia, have nothing like the

extensive utility in the treatment of spinal irritation that they

possess in that of true neuralgia. Of internal remedies, by far the most

useful in my hands have been sesquichloride of iron with small doses of

strychnia, and the milder vegetable bitters, especially calumba.

There is one special phase, however, of spinal irritation which is very

amenable to the direct, treatment, viz., cutaneous and mucous

tenderness. Whatever the "hyperaesthetic" part is within reach, so that

we can apply Faradization, we can almost certainly eradicate the morbid

sensibility very quickly. The secondary current of an electro-magnetic

or volta-electric induction apparatus is to be employed; the conductors

should be of dry metal and the negative one, which is to be applied to

the painful surface, should be in the form of the wire brush. The

positive pole is to be placed on some indifferent spot, and the negative

is to be stroked briskly backward and forward over the sensitive skin, a

pretty strong current being employed. The process is painful so much so

that it will often be advisable, with delicate patients, either to

administer chloroform or to inject morphia subcutaneously before the

Faradization. A very few daily sittings of four or five minutes length

will generally remove the morbid tenderness completely. Where the tender

part is within one of the cavities, at the rectum, bladder, vagina, or

pharynx, we must of course use a solid negative conductor of appropriate

form, and must content ourselves with applying it steadily to one point

after another of the sensitive surface.

The fact that Faradization proves so remarkably useful, in these cases

of spinal irritation with diffuse cutaneous or mucous tenderness, is in

itself a strong diagnostic between this sort of affection and the true

neuralgiae, which, as I have stated are seldom benefited, and are often

made worse, by the interrupted current, though the constant current

frequently mitigates or cures them.

Sometimes where it is not possible to apply the remedy directly to the

sensitive surface, we may nevertheless do great good by sending the

interrupted current through it. Thus, in gastric sensitiveness connected

with spinal tenderness in the upper dorsal region, I have seen very

great relief afforded by sending a current from the positive pole,

placed on the tender vertebrae, to a broad, negative conductor placed on

the epigastrium. And similarly, I have seen an acutely sensitive

condition of the neck of the bladder greatly soothed by the passage of a

current from a painful lumbar vertebra to the perinaeum immediately

behind the scrotum.

Undoubtedly, however, the more serious cases of spinal irritation will

yield only (if they yield at all) to a prolonged treatment in which very

skilful use is made of general hygienic measures, and especially of

morbal influences. As the brothers Griffin long ago pointed out,

although rest is useful in the early stages of this malady, if the

disease does not quickly yield to this and to appropriate tonic

medication, and perhaps local applications to the spine, it will not do

to keep the patient recumbent and confined to the house; on the contrary

at whatever cost of immediate discomfort, he (or she for these patients

are by far the most frequently females) must be roused up, and persuaded

or compelled to take out-door exercise, and if possible to travel, and

divert the mind by complete change of scene. When such expensive

remedies are out of the question, it seems better that patients, even

seemingly very feeble, should take to their ordinary avocations in life

again, and fight down the tendency to invalidism. But of course, the

decision on such a point must rest with the tact and judgment of the

practitioner in each individual case, for there are, doubtless,

instances in which the attempt to carry out such a plan, even

moderately, would break down the remaining strength, and make matters

worse than they were before.

In the worse case of spinal irritation that I ever saw, that of a young

lady, aged twenty-eight, there were pronounced anaemia and general

feebleness, the true hysteric _trepied_ of tender points, painful

irritability of the stomach, which baffled all medical advisers and

resisted almost every possible form of tonic and nervine medicines,

counter-irritation to the spine, and, in fact every thing that one dared

attempt with so feeble-looking a patient, but at once cleared up and was

quite cured after marriage. And there can be no question that a very

large proportion of these cases in single women (who form by far the

greater number of subjects of spinal irritation) are due to this

conscious or unconscious irritation kept up by an unsatisfied sexual

want. In some patients there cannot be a doubt that this condition of

things is indefinitely aggravated by the practice of self abuse; but it

would be most unjust to think that this is a necessary element in the

causation; on the contrary, it is certain that very many young persons

(women more especially) are tormented by the irritability of the sexual

organs without having the least consciousness of sensual desire, and

present the sad spectacle of a _vie manquee_ without ever knowing the

true source of the misery which incapacitates them for all the active

duties of life. It is a singular fact, that in occasional instances one

may even see two sisters inheriting the same kind of nervous

organization, both tormented with the symptoms of spinal irritation, and

both probably suffering from repressed sexual function, but of whom one

shall be pure-minded and entirely unconscious of the real source of her

troubles, while the other is a victim to conscious and fruitless sexual

irritation.

I have already causally alluded to the danger of mistaking mere myalgia

for spinal irritation and must again enforce this consideration upon the

reader. Myalgic tender points in the region of the spine are common

enough; and it would be easy without careful attention, to mistake them

for the deeper-seated vertebral tenderness which is truly characteristic

of spinal irritation. Hence the utmost care must be taken to ascertain

the true history of the commencement of the disorder whether it

succeeded to great and long continued fatigue of particular sets of

muscles, and whether it is specially aggravated by contractions of those

muscles, and relieved by their full extension. The differences of

treatment which depend on the diagnosis are too obvious to need dwelling

upon.

The question of administering remedies with the direct intention of

procuring sleep, for patients suffering from spinal irritation, often

becomes an important and a very difficult one. It is, for the most part,

highly objectionable to commence the use of such remedies; and yet

sleeplessness is a very distressing symptom with many patients, and is,

of course in itself exhausting and deleterious. For as long as we

possibly can, we should content ourselves with efforts to produce sleep

by the timely administration of nourishment. The same general rule of a

very generous (though not very stimulating) diet to be enforced as

carefully as in the case of sufferers from neuralgia. But it is

especially advisable in spinal irritation; that the patient should take

some food shortly before bedtime; and it is well, also to place food

within reach at the bedside, so that if he wakes up he may take some.

If, however, we are absolutely driven to employ hypnotics, we must

commence with the very mildest. The popular remedy of a pillow stuffed

with hops will sometimes suffice; and a better way of administering the

volatile principle of hops is to scatter a few hops on hot water in an

inhaler, and let the patient breathe the steam. Hot foot-baths, with

mustard, are also very useful. If these fail, chloral, in moderate doses

is probably the best and safest remedy, and, with care not to give too

much, we may go on using the same dose without increase for a good many

times.

FOOTNOTE:

[48] Reynolds's "System of Medicine," vol. ii., Art. "Spinal

Irritation."

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