_IMMEDIATE:_ Usually no sensation, occasionally mild pain
_LOCAL:_ (Four distinct reactions depending on degree of sensitivity):
1. Papule with a central punctum
2. Small vesicles grouped around bite site with swelling and little
redness
3. Giant urticarial lesion with central punctum and surrounding brawny
edema
4. Hemorrhagic nodular-to-bullous lesions on hands and feet—the
characteristic “kissing bug bites”
_ANAPHYLACTIC SHOCK:_ Rare, but reported
_DEATHS:_ None reported