---- platelets, 190
---- ---- alkali in, 47
---- ---- in chlorosis, 193
---- ---- origin of, 192
---- poisons, leucocytosis from, 145
Bone-marrow, 105, 112
---- ---- carcinoma of, 178
---- ---- cells of, in various animals, 106
---- ---- changes in anaemia, 117
---- ---- changes in lymphatic leukaemia, 118
---- ---- changes in pernicious anaemia, 117, 129
---- ---- connection with leucocytosis, 155
---- ---- connection with leukopenia, 189
---- ---- development of leucocytes in, 108-110
---- ---- giant cells in, 107
---- ---- of dog, 114
---- ---- protective organ, 111
---- ---- tumours of, 115
Cachectic leucocytosis, 146
Camphor, eosinophilia from administration of, 154
Catarrhal jaundice, volume of corpuscles in, 23
Charcot's crystals, 151
Chemiotaxis, 139
Chemiotaxis, positive, 139
---- negative, 140
Chenzinsky's fluid, 43
Chloroform narcosis, leucocytosis from, 145
Chlorosis, platelets in, 193
Coagulation, rate of, 23
---- connection with platelets, 192, 193
---- in purpura, 193
Coagulometer, 23
Compensatory eosinophilia, 154
Congenital syphilis, leucocytosis in, 147
Corpuscles, at high altitudes, 8
---- enumeration of, 5
---- influences on, 7
---- red _see_ Red corpuscles
---- volume of, 21
---- white _see_ Leucocytes
Crisis, blood, 62
---- in infective fevers, 145
Diabetes, glycogen in blood in, 75
Differential count of corpuscles, 31
---- staining, theory of, 37
Digestion, leucocytosis of, 102
Diphtheria, myelocytes in, 78, 146
Dog, bone-marrow in, 114
Dry preparations, 32
---- substance of blood, 20
Duehring's disease, eosinophilia in, 156
Electricity, resistance to, of corpuscles, 25
Enumeration of corpuscles, 5, 31
---- ---- ---- in anaemia, 12
Eosine-methylene blue methods, 43
Eosinophil cells, 78, 185
Eosinophil cells after splenectomy, 89, 94
---- ---- development of, 109
---- ---- in birds, 130
---- ---- in leukaemia, 176, 177
---- ---- in malignant lymphoma, 163
---- ---- in mammary glands, 163
---- ---- origin of, 160, 161
---- ---- secretion in, 134
---- leucocytosis, 148
---- ---- causes of, 165
---- ---- distinction from leukaemia, 178
---- ---- occurrence, 150-154, 158
---- ---- origin of, 154
---- myelocytes, 78
---- ---- in leukaemia, 174
Erythroblasts, in leukaemia, 180
---- in spleen, 99
---- nuclei of, 57, 61
---- origin of, 55
---- varieties of, 55, 56
Exercise, leucocytosis from, 144
Ferrometer, 16
Fevers, complication of leukaemia, 177, 181
---- leucocytosis in, 144, 146
---- spleen in, 98
Fixation of films, 34
Formalin as fixative, 35
Giant cells in bone-marrow, 107
Gigantoblasts, 56
Glycogen in gonorrhoeal pus, 46
---- in platelets, 192
Glycogen in polynuclear leucocytes, 75
---- stain for, 45
Gonorrhoeal pus, glycogen in, 46
---- ---- mast cells in, 160
Granulation, absence of, 118, 129, 182
---- chemical nature of, 134
---- ripening of, 108
Granules, 121
---- connection with emigration, 132
---- distribution of, 130
---- function of, 127
---- history of, 121-130
---- intravital staining of, 124
---- intravital staining of by neutral red, 125
---- reaction of, 126
---- secretory nature of, 134
---- specificity of, 133
---- survival staining of, 125
Guinea-pig, leucocytes in, 85, 112
Haematocrit, 21
Haematocytometer, 4
Haematoxylin-eosine mixture, 42
Haemoconiae, 193
Haemoglobin, amount of, 13
---- connection with specific gravity, 18
---- equivalent in anaemias, 49
---- estimation of, 14-17
Haemoglobinometer, 15
Haemorrhages, acute, 51
Haemorrhagic small-pox, pseudo-lymphocytes in, 79
Hayem's solution, 5
Heat as fixative agent, 34
Hedgehog, splenectomy in, 107
Helminthiasis, eosinophilia in, 150
High altitudes, erythrocytes at, 8-12
---- ---- poikilocytosis at, 9
Hodgkin's disease (malignant lymphoma), 101, 102
---- ---- eosinophil cells in, 165
Hyaline cells _see_ Large mononuclear leucocytes
Hygraemometry, 20
Infectious diseases, leucocytosis in, 146, 147
---- ---- myelocytes in, 77
---- ---- splenic enlargement in, 99
Intestinal diseases, leucocytosis in, 102
Intravital staining, 124
Iron, administration of, 16
---- connection of, with haemoglobin, 16-18
---- in blood, 16
---- in eosinophil cells, 134
Isotonic point of corpuscles, 25
Jenner's stain, 44
Kresyl-violet-R, metachromatism with, 76
Kurloff's researches, 85
Lactation, eosinophil cells in, 163
---- mast cells in, 163
Large mononuclear leucocytes, 73, 112, 185
---- mononuclear leucocytes in measles, 113
Leucocytes, 71
Leucocytes, atypical forms, 77, 179
---- enumeration of, 5
---- in birds, 131
---- in guinea-pig, 85-87, 112
---- places of origin, 81
Leucocytosis, 138
---- active, 142
---- agony, 146
---- cachectic, 146
---- chemically produced, 189
---- classification of, 142
---- diagnostic importance of, 146
---- eosinophil _see_ Eosinophil leucocytosis
---- function of bone-marrow, 110
---- in anaemia, 146;
congenital syphilis, 147;
measles, 113, 145, 189;
parotitis, 144;
pneumonia, 144, 174;
rheumatism, 144;
tumours of bone-marrow, 116;
typhoid, 146, 189
---- mixed, 143, 167
---- of digestion, 102
---- origin of, 146
---- passive, 142
---- physiological, 144
---- polynuclear neutrophil, 143
---- theories of, 138
Leukaemia, acute lymphatic, 118, 170;
chronic, 170;
suppuration in, 105
---- myelogenic, 169
---- ---- atypical cases, 182
Leukaemia, myelogenic, atypical leucocytes in, 179
---- ---- characteristics of, 174-181
---- ---- complicated with other diseases, 174, 181
---- ---- contrasted with eosinophilia, 178
---- ---- contrasted with pneumonia, 174
---- ---- diagnosis from blood, 171
---- ---- eosinophilia in, 176
---- ---- mast cells in, 179
---- ---- mitoses in, 180
---- ---- mononuclear eosinophils in, 175
---- ---- myelocytes in, 174
---- ---- origin of blood condition, 183, 187
---- ---- pleuritic exudation in, 186
---- ---- polynuclear myelocytes in, 175
Leukopenia, 188-190
---- experimental, 140
---- in various diseases, 189
Liver, granules in, 127
Lymphaemia _see_ Lymphocytosis
Lymphatic glands, 100
---- ---- myelocytes in, 110
Lymphocytes, 71
---- in disease of lymphatic glands, 101;
lymphatic tumours, 101;
polynuclear leucocytosis, 143
Lymphocytosis, 101, 103, 144
---- after splenectomy, 90, 94
---- causes of, 101-103
---- in leukaemia, 170
---- origin of, 104
Lymphoma malignum (Hodgkin's disease), 101, 102
Malignant tumours, eosinophilia from, 153
Mast cells, 76, 160
---- ---- halo round, 135
---- ---- in gonorrhoea, 162;
leukaemia, 179;
purpura (horse), 136
---- ---- in skin, 160
---- ---- origin of, 162
---- ---- secretion in, 135
Measles, leukopenia in, 145, 189
Medicinal eosinophilia, 154
Megaloblasts, 56-62
---- in bothriocephalus anaemia, 65;
leukaemia, 180;
pernicious anaemia, 62, 66;
tumours of bone-marrow, 117
Megalocytes, 64
Metachromatism in mast cells, 76
Methylal method, 44
Microblasts, 57
Mitoses in leukaemic blood, 180
Mononuclear leucocytes, 73, 112, 116
---- ---- origin of, 113
---- ---- power of motion, 185
Mouse, polynuclear cells in, 131
---- spleen in, 99
Myelaemia, origin of, 183, 187
Myelocytes, 77, 110
---- importance in blood, 110;
in diphtheria, 78
---- in anaemia pseudoleukaemica infantum, 77;
bone-marrow tumours, 117;
leukaemia, 174;
lymphatic glands, 110;
lymphatic leukaemia, 118;
pneumonia, 78
Myelocytes, eosinophil, 78, 175
Myelogenic leukaemia _see_ Leukaemia, myelogenic
Nasal polypi, eosinophil cells in, 159
Neutral red, 125
Neutrophil granulation, absence of, 118, 129
Neutrophil leucocytes _see_ Polynuclear neutrophil leucocytes
Neutrophil pseudolymphocytes, 79
Normoblasts, 56, 57-62
---- in anaemias, 62;
leukaemia, 180
Nose, diseases of, eosinophil cells in, 159
Nucleated red corpuscles _see_ Erythroblasts
Old granulations, 109
Oligaemia, 2
Oligochromaemia, 2
Oligocythaemia, 2
Ozonophores, 129
Pacini's solution, 5
Paralysis, unilateral, corpuscles in, 6
Parotitis, leucocytosis in, 144
Passive leucocytosis, 142
Pemphigus bullae, 156
---- ---- eosinophilia in, 150
Pernicious anaemia, bone-marrow in, 129
Pernicious anaemia, haemoglobin equivalent in, 49
---- ---- megaloblasts in, 63, 65
---- ---- prognosis, 66
Phagocytosis, 139
Phosphorus poisoning, spleen in, 98
Pilocarpine, lymphocytosis from, 103
Platelets _see_ Blood platelets
Pleuritic exudations, in leukaemia, 186
---- ---- pseudo-lymphocytes in, 79
Pneumonia, contrast with leukaemia, 174
---- glycogen reaction in, 75
---- leucocytosis in, 141, 146, 152
---- myelocytes in, 174
Poikilocytosis, 52
---- at high altitudes, 9
---- explanation of, 54
---- from heating, 54
Polychromatophil degeneration, 49
Polynuclear neutrophil leucocytes, 74, 112, 185
---- ---- ---- diminution of in lymphatic leukaemia, 118;
in myelogenic leukaemia, 182
---- ---- ---- increase of _see_ Leucocytosis
---- ---- ---- movement in, 184
---- ---- ---- secretion in, 137
Post-febrile eosinophilia, 152
Posthaemorrhagic anaemia, blood in, 51
---- ---- ---- platelets in, 193
Potassium chlorate, leucocytosis from, 155
Pregnancy, leucocytosis in, 144
Pseudo-eosinophil cells, 85, 133
---- ---- ---- secretion in, 137
Pseudo-lymphocytes, 79
Purpura, of horse, mast cells in, 136
---- platelets in, 193
Pyknosis, 61
Pyrodin, leucocytosis from, 145
Quadratic ocular diaphragm, 31
Quantity of blood, estimation of, 2
Red corpuscles, 48
---- ---- acute swelling of, 21
---- ---- at high altitudes, 8-12
---- ---- connection with spleen, 99
---- ---- in anaemia, 49-57
---- ---- isotonic point of, 25
---- ---- nucleated _see_ Erythroblasts
---- ---- number of, in health, 7
---- ---- number of differences in age, 7;
in sex, 7;
food, 7;
from vasomotor influences, 11
---- ---- polychromatophil degeneration in, 49
---- ---- size of, 12
---- ---- volume of, 21
Retinal vessels in anaemia, 3
Rheumatic fever, leucocytosis in, 152
Scarlet fever, leucocytosis in, 146
---- ---- lymphatic glands in, 110
Separation of serum, 24
Serum, specific gravity of, 20
Sex, influence on red corpuscles, 7
---- ---- specific gravity of blood, 17
Shock, effect of, on specific gravity of blood, 18
Size of red corpuscles, 12
Skin diseases, eosinophilia in, 150
Small-celled infiltration, 105
Specific gravity of blood, 17
---- ---- ---- ---- connection with haemoglobin, 18
---- ---- ---- ---- in anaemias, 18
---- ---- ---- ---- influences acting on, 18
---- ---- ---- ---- of serum, 20
Spleen, 84
---- as blood forming organ, 84, 99
---- enlargement of, in fevers and phosphorus poisoning, 98
---- excision of _see_ Splenectomy
---- functions of, 98
---- in guinea-pig, 91, 93, 99
---- tumours of, 97, 98
Splenectomy, effect of on blood in hedgehog, 107;
in guinea-pig, 88;
in man, 93, 95, 96, 113
Staining, theory of, 36
---- vital, 124
Stimulation forms of leucocytes, 79
Stroma of corpuscles, influence on specific gravity of blood, 19
Suppuration in lymphatic leukaemia, 104;
in myelogenic, 177;
in pemphigus, 157
Survival staining, 125
Thyroid, changes after splenectomy, 84
Time of life, influence of, on corpuscles, 7
Toxic leucocytosis, 145
Transitional forms of leucocytes, 74, 112
Triacid stain, 42, 131
Trichinosis, eosinophilia in, 152
Tropics, influence of, on red corpuscles, 12
Tuberculin injections, eosinophilia from, 152
---- ---- lymphocytosis in, 103
Tumours of bone-marrow, 115
Typhoid fever, leukopenia in, 146, 189
Urticaria, eosinophilia in, 150
Vital staining, 124
Volume of corpuscles, 21
White blood corpuscles _see_ Leucocytes
Whooping cough, lymphocytosis in, 103
Worms _see_ Helminthiasis
Wright's coagulometer, 24
CAMBRIDGE: PRINTED BY J. AND C. F. CLAY, AT THE UNIVERSITY PRESS.