“To have desired to act ‘rightly,’ and to be able to think of success in

life as measured by the fulfilment of that desire, is the indication and

warrant of true greatness of character. We Englishmen have ever loved to

recognise this noble kind of devotion in our national heroes.”

VI

METCHNIKOFF AND TOLSTOI

The Darwin celebration at Cambridge, in June 1909, brought a wonderful

assemblage of celebrated biologists from all parts of the world to this

country. There never has been seen such a company of great discoverers

of all nationalities in the field of natural history and the science of

living things, as were present in the University of Cambridge during

that week. Even philosophers, moralists, and jurists were present to

join with the one great political leader of our own country who really

knows and appreciates the importance of the scientific study of

Nature—the Right Hon. Arthur J. Balfour—in his fervent and heartfelt

tribute to the influence of Darwin’s work and theory in all departments

of human knowledge, thought, and activity. One of the most remarkable

men present was Elie Metchnikoff. He represented both Russia, the

country of his birth and earlier scientific work, and his adopted

country, France, where, as sub-director of the Institut Pasteur, his

later and most important researches have been carried on. Russia was

also represented by Salensky, late director of the Museum of St.

Petersburg, well known to us all as a discoverer in the embryology

(growth from the egg) of marine animals, and by Timiriazeff, the

botanist, renowned for his work on the mode in which leaf-green or

“chlorophyll” enables green plants to obtain their food from the gases

of the atmosphere. France had other representatives in Edmond Perrier,

director of the Paris Museum, and Prince Roland Bonaparte.

Metchnikoff was one of the four representatives selected by the

University to deliver orations in the Senate House in honour of Darwin.

He especially drew attention to the influence of Darwin’s theory on the

study of disease. The recognition of the derivation of man from animal

ancestors, and of the complete community of the structure and the

chemical activity of the organs of man with those of the organs of

animals, had made (he said) the study of the diseases of animals a

necessary feature in the understanding of the diseases of man. The

far-reaching principle of Darwin that the mechanisms and processes

observed in the bodies of plants and of animals (including man) must

have been selected in the struggle for existence and perpetuated,

because of their utility, led Metchnikoff to inquire what is the value

or use of the process called inflammation and of the “eating

corpuscles,” or “phagocytes” (so named by him), which wander from the

blood into inflamed tissues. This question had led him to the discovery

that the phagocytes engulf and destroy disease-germs, and are the great

protectors of the animal and human body against bacteria and other germs

which enter cut and wounded surfaces, and would start disease were there

not “inflammation,” which is nothing more nor less than a

nerve-regulated stagnation of the circulation of the blood at the

wounded spot, and the consequent arrival at this spot of thousands of

“phagocytes,” which pass out of the stagnant blood through the walls of

the fine blood-vessels. These armies of phagocytes proceed to eat up and

destroy all the germs which fall on to the wound—from the air, from

dirty surfaces, and from the skin. The utility of inflammation and its

gradual development, according to Darwinian principles, in the animal

series, was shown twenty years ago by Metchnikoff. His important work on

“immunity” and on infection and on protection against germ-caused

disease is thus seen to be one of the many flourishing and valuable

branches of knowledge which have originated from Darwin’s great

conception and his example in experiment and inquiry.

Metchnikoff is now devoting all his attention to the possibility of

prolonging human life. The facts seem to show that if we ate and drank

only what is best for us, and led lives regulated by reason and

knowledge, we should, nearly all, attain to 80 or even 100 years of age,

having healthy minds and healthy bodies. We should die quietly and

comfortably at the end, with much the same feeling of contentment in

well-earned final repose as that which we now experience in going to

sleep at the end of a long and happy day of healthy exercise and

activity. Metchnikoff thinks that the causes of too early death may be

ascertained, and when ascertained avoided or removed. In 1870, in a

little book on _Comparative Longevity_, I distinguished what we may call

the “possible life,” or “potential longevity,” of any given human being

from his or her “expectation” of life. Potential longevity has been well

called our “lease” of life. It is probably not very different in

different races of men or individuals, and is probably higher than King

David thought, being 100 to 120 years, and not merely 70 years. We all,

or nearly all, fail to last out our “lease” owing to accidents,

violence, and avoidable, as well as unavoidable, disease; so that 70

years is named as our tenure when the injury done to us by unhealthy

modes of life and by actual disease are considered as inevitable.

Metchnikoff proposes to discover and to avoid those conditions which

“wear down” most of us and produce “senility” and “death” before we

have really run out our lease of life.

Human beings die most abundantly in the earliest years of life.

Statistics show that at birth the chance or expectation of life is only

45 years, whilst at 10 years old you may expect to live to be 61. At 30

you have not a much better chance—you will probably, if you are what is

called a “healthy” life, die when you are 65. But if you survive to be

50 you may expect, if you have not any obvious disease or signs of

“break up,” another twenty years, and will probably die at 70; surviving

to 60, you may expect, if you are what passes for “healthy,” to live to

73. Now, it is especially with regard to life after 40 or 50 years of

age that Metchnikoff is interested. Those who have survived the special

dangers and difficulties of youth, and have arrived at this mature age,

ought to be able to realise much more frequently than they do something

like the full “lease of life.” There seems to be no reason why they

should not avoid the usual rapid “senile changes” or weakness of old

age, and survive, as a few actually do, to something like 100. The

causes of “senile change” and the way to defeat their operation are what

Metchnikoff is studying. Hardening of the walls of the arteries set up

by certain avoidable diseases contracted in earlier life, and by the use

of alcohol (not only to the degree which we call “drunkenness,” but to

such a degree as to make one depend on it as a “pick-me-up”), is an

undoubted cause of that weakness and liability to succumb to other

diseases which is so general after 50 years of age. The causes which

produce hardened arteries can be avoided. Another cause of senile

changes is declared by Metchnikoff, to arise from the continual

absorption of poisonous substances produced by the decomposition of

partially digested food in the lower bowel or large intestine. This is

at present the chief subject of his study. It is to prevent the

formation of these poisons that he has introduced the use of sour milk,

prepared with the lactic ferment. Since the Cambridge celebration he has

been in London in order to examine the condition of certain patients

from whom a distinguished English surgeon has found it necessary to

remove the “large intestine.” Metchnikoff wishes to ascertain what

bacteria, poison-producing or other, are present in these patients, and

what is their general chemical condition now that this poison-producing

part of the digestive canal has been taken from them.

In Paris, Metchnikoff has some very interesting experiments in progress

with bats. He uses the large tropical fruit-eating bats, or “flying

foxes.” They have a very short intestine, and very few bacteria and of

very few kinds are to be found in its contents. On the other hand, there

are as many as thirty distinct kinds of bacteria producing putrefaction

or other chemical change in the digestive canal of man—and their

quantity is gigantic. They pervade the whole contents of the human

digestive canal by millions. By properly feeding the flying foxes in his

laboratory in Paris Metchnikoff has actually succeeded in getting rid of

all bacteria from their digestive canal, so that he now has adult

mammalian animals, not very remote from man in their structure, food,

and internal chemistry, which are absolutely free from the intestinal

parasitic bacteria which he supposes to cause poisoning and senile

changes in man. It is obvious, without pursuing the matter into further

detail here, that Metchnikoff is now in a position to test his views as

to the action of particular kinds of bacteria—he has animals which are

free from them. He can make an experiment, keeping some of his bats

still free from bacteria and causing some to be largely infected by this

or that kind, and he can compare the result in regard to the health and

chemical condition of the animals. So, too, the patients from whom the

lower intestine has been removed may very probably furnish him (through

his assistant who remains in London) with important facts for comparison

with the condition of persons who have not been deprived of this part of

the digestive apparatus.

I have given this sketch of what my friend is doing in order to furnish

some notion of the kind of investigation which he pursues. He does not

expect to extend the “lease” of human life, but by ascertaining in a

definite scientific way the true rules of internal and external

“hygiene” he does hope to give mankind an increased “expectation” of

life; in fact, to enable a vastly larger number of men and women to

enjoy that lease to the full, and to die without disappointment and

regret, even with contentment and pleasure, at the end of it.

Metchnikoff was in Russia in the spring of 1909, and spent a day with

Tolstoi. They were “fêted” and photographed together, the greatest

artist and the greatest scientist of Russia. Tolstoi is 81 years of age.

He took Metchnikoff out alone for a drive in his pony-cart so as to talk

with him without interruption. “What do you think of life?” was the

first question he asked, and one which it took my friend some time to

answer. In regard to vegetarianism the two great men did not agree. When

Metchnikoff declared that there was less cruelty on man’s part in

killing wild animals to eat them than in leaving them to die by the

tooth and claw of predaceous animals or from starvation, Tolstoi

observed that that was argument and reason, and that he paid no

attention to them; he only guided himself (he said) by sentiment, which

he felt sure told him what was good and right! He was, however, deeply

interested in an account of the cannibalism of savage races of men,

concerning which he seemed to be quite uninformed. He also was

profoundly interested in Metchnikoff’s view that Goethe, in the second

part of _Faust_, is chiefly bent upon depicting the persistence of the

amorous passion in old age—of which Goethe himself was an example—and

Tolstoi declared that this gave a new meaning to the poem, which he had

always hitherto found dull and unintelligible. But when Metchnikoff

described in glowing words the joy and even rapture with which man will

hereafter welcome the repose and mystery of death, having completed a

long and healthy life of some hundred years, Tolstoi declared that this

was indeed a fine conception, although it was entirely subversive of his

own notions as to the significance of life and death. Tolstoi also

stated that he had written his stories rapidly and without effort, but

that his essays on morality and religion had cost him great labour; and,

further, that he could not now remember the former, though the latter

still were developing and incessantly occupied his thought.

It was admitted with regret by Darwin that he ceased in middle age to

care for poetry and art, though there seems to be no doubt that he

mistook fatigue and preoccupation of mind for a real change in taste and

power of appreciation. It is interesting to place beside this the case

of the great literary artist, Tolstoi, who not only frankly confesses

that he refuses to be guided by reason and follows sentiment, but is

also profoundly ignorant upon all the most ordinary topics of human life

outside his own village, and of all Nature and her workings. Would

Tolstoi have been a greater or a smaller artist if he had had a larger

knowledge of the things that are? Was Darwin’s great scientific

achievement really related to an innate indifference to what is called

“poetry”? I will not now discuss the matter, but I am convinced that so

far as natural gift is concerned, the keenest scientific capacity is not

only compatible with the fullest sensibility to art and with the power

of poetical vision and expression, but is often accompanied by them;

and, further, that the work of an artist, if he is a great artist,

cannot be hampered by knowledge. It is only the small talent or the

feeble genius that can be paralysed rather than developed by the fullest

experience and the widest knowledge. Necessary incompatibility of mental

qualities has no place in this matter; what has led to the erroneous

assumption that it has, is the excessive exercise by exceptional

individuals of certain powers—a specialism necessary for effort and

success, but deliberately chosen, and not due to an inborn

one-sidedness.

VII

THE LAND OF AZURE BLUE

The Côte d’Azur whither many of my readers will be travelling—in

thought, if not in reality—about Easter time, is well named the Land of

Azure Blue, for it is the blueness of the sea, of the sky, and of the

distant rocks and mountains, as well as much of the vegetation, which is

when the sun shines, its special charm. And although one has some wet

and some cloudy days, yet the sun does shine there with a strength and

brilliancy not to be enjoyed in the early part of the year on the

Atlantic and North Sea coast. This tract of country, more commonly known

to English people as the Riviera, has very special meteorological

conditions owing to its position as the narrow strip of shore-line

existing between the vast mass of the Western Alps and the Mediterranean

Sea. It is warmed by the sea, and lies too close under the mountains to

be caught by any winds from the north, and at many points is also

effectively protected from both east and west winds by rocky spurs of

the great mountain chain.

The Riviera is a constant source of delight to those who love flowers

and beautiful vegetation of all kinds. But few of its visitors

appreciate the fact that it is really from end to end one big garden,

cultivated for ages by its inhabitants, and full of plants introduced by

man which at present seem at first sight to be characteristic natives

of it, but are, in reality, quite distinct from its primitive

vegetation. This primitive vegetation is now represented only in what is

locally called the “maquis”—what we should, perhaps, term the “scrub”

or “bush” in English. It comprises some pines, the juniper, the lovely

rock roses, balsams, rosemary, the giant heath (bruyère), from which our

briar-root pipes are made, the larger thyme, the myrtle, the rose of

Provence, two kinds of lavender, and many aromatic plants with grey

hairy leaves, and often provided with sharp thorns as additional

defences against browsing goats. The delicious perfumes of these hardy

inhabitants of the dry, rocky grounds, where little or no grass can

flourish, are developed by them as a protection against browsing

animals, who cannot tolerate much of these pungent volatile oils,

although mankind extracts them and uses them in the manufacture of such

scents as eau-de-Cologne and also in cookery.

Many a visitor to the Riviera never strays from the cultivated fields

and roadways into this scrub-land. The olive tree, which forms so

prominent and beautiful a feature in the panorama of gardens which

unrolls itself as we steam or drive along the coast from Toulon to

Mentone and from Mentone to Genoa and Spezzia, is not a native plant; it

was introduced in prehistoric times, and has been again and again

re-established by emigrants from Italy; but it was brought to Italy from

the East. It is astonishing how many of the cultivated trees of the

Riviera have the same kind of history—the vine came from India in

prehistoric times, the fig tree more recently from Persia, the lemon

from India, the orange and the peach tree from China. All of them were

introduced in very ancient times to the eastern parts of the

Mediterranean basin, and so gradually were carried to the shores of the

Ligurian sea, and would die out here were they not to a certain extent

under the care of ownership.

The so-called “mimosa,” so abundant here, with its pretty,

sweet-scented, yellow blossom, is an Australian acacia, only introduced

some sixty years ago; whilst the eucalyptus—a most picturesque and

effective addition to the landscape—is a still later introduction from

Australia. The cypress, that darkest and most shapely of conifers, long

lines of which proclaim to the traveller as he passes Avignon his

arrival in the true “South,” is not a native of these parts, although it

flourishes in suitable situations. It was introduced in mediæval times

from the East. So, too, the palms, though some have been cultivated for

centuries, have been largely imported from extra European localities in

the last century. There is a native European palm. It is a kind of

fan-palm, and grows here. I have gathered it in Sicily. It does not

“rear its stately head” more than a foot from the ground, and is known

to botanists as _Chamærops humilis_. The gigantic Mexican agave and the

prickly-pear cactus were introduced in the seventeenth century from the

New World, though, according to Sir Herbert Tree’s scenery, they were

growing at Cape Miseno in the time of Antony and Cleopatra! Bamboos of

many kinds have been introduced here from the Far East, and flourish

exceedingly.

The orange tree was brought from India (whither it was carried from

China) and established in Southern Europe in mediæval times, though

known to the ancient Greeks and Romans. There are as many as 120

different varieties of the orange tree now cultivated on the shores of

the Mediterranean, including, besides those which are valued for their

sweet juicy pulp, those which furnish bergamot oil and similar aromatic

products. The “issue pea” of old apothecaries, which was bound into a

cut made in a patient’s flesh for the purpose of producing inflammation

and suppuration, with the notion that such treatment was beneficial, was

a minute unripe orange dried, and, no doubt, to some extent, antiseptic.

Besides the introduced trees, we find, in ground which has been more or

less under cultivation, and not, therefore, of the nature of the

“maquis,” or scrub-land, some beautiful plants, such as the narcissus,

iris, and various lilies. One very small and graceful tulip is, I

believe, regarded as native to the soil, but a magnificent crimson

tulip, as large as the varieties cultivated in English gardens, which I

have found abundantly in open park-like land under olive trees at

Antibes, is said to have been introduced from Persia in the Middle Ages,

and to have taken kindly to the Riviera. It is the _Tulipa oculus

solis_. In the same locality were growing many brilliantly coloured

“stellate” anemones.

There is, of course, a third group or “lot” of plants on the Riviera,

which consists of those brought from all parts of the world during the

past century, and regularly cultivated and cared for in gardens. The

climate of the Riviera enables the gardener to grow all sorts of

sub-tropical plants in the open air, and a long list of them could be

given. The wonderfully brilliant crimson creeper, Bougainvillia, covers

walls by the roadways, and even the railway stations, with its rich

colour at this season. A delightful book by the distinguished botanist,

Professor Strasburger, describing and picturing in colours many of the

cultivated as well as the wild plants of the Riviera, has lately been

published (in English) at a small price.

The animals which come under the notice of those who go in search of

spring sunshine to the Riviera are far less numerous than the plants.

But there is one which is dear to all, although it makes such a noise

for an hour or so about sunset that some people are irritated or even

alarmed by it. This is the little green tree-frog, Fig. 1, which now

comes forth from its winter sleep, and assembles in thousands—guided by

the “croak” or “call” which is produced by the males. The females have a

very small voice comparatively. I kept two—a male and female—through a

winter in London, and when the spring came the male terrified the

household one night by unexpectedly uttering his cry—loud and sharp—to

which the female replied. “Wharr! biz” is the nearest expression I can

give in letters to the two sounds. After a great many evenings spent in

these rhythmical declamations, the little frogs collect round pools and

tanks, and at last drop from the trees into the water, and there deposit

their spawn. When producing his cry the male distends the skin of his

throat like a balloon. The air is driven alternately from it into the

lungs and back again over the vocal chords, which vibrate with no

uncertain sound. These little frogs are easy to keep in an inverted

bell-jar or in a fern-case, but must be fed regularly with flies and

spiders, which they catch by a sudden dab of the tongue at the moment of

alighting from a long leap on to the glass where the insect is crawling.

They can hold on to smooth glass or leaves by means of their sucker-like

toes (Fig. 1).

The colour of the upper surface of the South European tree-frog is a

most vivid and smoothly laid-on grass-green. Occasionally the colour

becomes altered to a brownish purple, but returns after a day or two to

its usual bright green tint. A great rarity is the blue variety of this

frog—the enchanted Prince of the Côte d’Azur—blue as the sky and the

sea around him—the true _genius loci_. I obtained one a few years ago

at Mentone, and kept it alive for three years in London. Its blue was

the blue of the forget-me-not or the finest turquoise. When it died (I

believe of old age, and not from discomfort or disease) I examined its

skin very carefully with the microscope, and compared it with that of

the ordinary green tree-frog, in order to make out the cause of their

difference in colour.

[Illustration: FIG. 1.—The little green tree-frog or “rainette” of the

Riviera (_Hyla arborea_). From Professor Gadow’s volume on _Reptiles and

Amphibia_—in the “Cambridge Natural History”—published by Macmillan &

Co., by whose permission this figure is here produced.]

At Mentone there is a little shop where one may purchase green

tree-frogs and ornamental cages in which to keep them. Every year the

dealer has two or three specimens of the blue variety on sale—their

backs and heads looking like bits of turquoise-blue kid. Visitors have

sometimes wrongly supposed that the blue frogs had been artificially

changed in colour, but they are real, natural varieties. A similar

substitution of blue for green has been noticed as a rare variation in

other kinds of frogs and toads in other countries. It really consists in

a suppression of yellow pigment.

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