_Guinea pig 59. Gray and white. Weight, 375 grams. Diet, oats._
October 3: 2 p. m., 3.75 cc (0.2 gram per kilo) injected into
peritoneal cavity; 2.15 p. m., reflexes increased but not markedly; 4
p. m., reflexes still more increased; no other symptoms; 5.30 p. m., no
symptoms.
October 4: 8.50 a. m., guinea pig alive and active.
_Guinea pig 58. Brown and white. Weight, 380 grams. Diet, oats._
October 3: 2 p. m., 3.8 cc caffein (0.2 gram per kilo), 2 per cent
solution, injected into peritoneal cavity; 2.10 p. m., hind legs
extended, then tetanus; attack lasted a few seconds, after which pig
raised himself on his legs, but reflexes remained much exaggerated; 4
p. m. to 5.30 p. m., no symptoms of caffein intoxication.
October 4: 8.50 a. m., guinea pig alive and active.
_Guinea pig 56. Gray and white male. Weight, 440 grams. Diet, oats._
October 1: 11.30 a. m., received 4.6 cc of 2 per cent caffein solution
(0.2 gram per kilo) into abdominal cavity; 11.45 a. m., stiffness and
rigidity of posterior extremities, reflexes increased; 12.30 p. m.,
hind legs paralyzed, reflexes increased; 4.35 p. m., no symptoms,
guinea pig in good condition.
October 3: Still alive in good condition.
October 14: Died. _Autopsy_: Anterior lobe of right lung hepatized.
Small portion of small intestine edematous. Other organs normal.
_Guinea pig 55. White and yellow male. Weight, 690 grams. Diet, oats._
October 1: 11.30 a. m., received 6.5 cc of 2 per cent solution caffein
(188 mg per kilo) into peritoneal cavity; 11.40 a. m., stiffness in
all extremities, reflexes markedly increased; 12.30 p. m., reflexes
increased, anterior and posterior extremities paralyzed; 3 p. m., found
dead.