_Guinea pig 41. Weight, 700 grams. Diet, oats._
April 1: 3.30 p. m., 4.5 cc 2 per cent caffein (130 mg per kilo)
injected into peritoneal cavity. 5.35 p. m., symptoms present but no
tetanus.
April 2: Found dead about 2 p. m., duration of life about 22 hours.
_Autopsy_: Subcutaneous hemorrhage at the point of inoculation; serious
exudate on visceral and parietal peritoneum with marked inflammation of
peritoneum; portions of intestines showed slight enteritis.
_Guinea pig 49. Male. Weight, 370 grams. Diet, oats._
April 1: 3.15 p. m., 2.5 cc 2 per cent caffein (135 mg per kilo)
injected into the peritoneal cavity; 5.30 p. m., symptoms present;
reflexes increased, but no tetanus. Guinea pig survived.
_Guinea pig 47. Female. Weight, 550 grams. Diet, oats since about
February 4._
March 17: 3.30 p. m., 3.5 cc 2 per cent caffein (127 mg per kilo)
injected into peritoneal cavity; 4.35 p. m., increased irritability
present, but not marked; 5.40 p. m., symptoms about the same as before.
March 18: 2.30 p. m., condition good; no symptoms. Survived.
_Guinea pig 50. Female. Weight, 290 grams. Diet, oats._
April 1: 3.30 p. m., 2 cc 2 per cent caffein (138 mg per kilo) injected
into peritoneal cavity; 5.35 p. m., symptoms present; reflexes much
increased, but no tetanus. Survived.