THE GERM THEORY A CENTURY AGO.

Under this caption the British Med. Journal for February 11, 1888,

contains an editorial review of a pamphlet of 87 pages, published in

1788, and entitled: “_A Treatise on Fevers, wherein their Causes are

exhibited in a new point of view, to prevent Contagion; and Putrid Sore

Throat, Inflammatory Fluxes, Influenza, Consumptions, as well as the Low

Nervous Fevers that terribly affect the Spirits, may be cured with

ease_.”

The most remarkable part of the book is the speculative or explanatory

part, consisting of an exceedingly ingenious argument, based upon the

analogy of admitted facts, to prove that the cause of contagious fevers

is some invisible noxious matter in the air. Of the intimate nature of

this matter he says: Some consider it to be a sulphurous exhalation from

the earth; but this cannot be, for, if so, acrid and sulphurous fumes

would increase it, instead of checking or annihilating it. Another

theory is that it is due to the products of putrefaction; but how can

dead putrid matter ever get such activity as to work such astonishing

results? It must therefore be something endowed with a more powerful

activity than anything belonging to the mineral kingdom or simply

putrefying matter, and must, therefore, be something “actually living.”

He further concludes that these living organisms must have an existence

independent of the body in which they are found. For this view,

surprising and novel enough at first, loses some of its singularity, if

we search for resemblances elsewhere. Now, just as it was well known

that itch is due to the presence of acari, insects visible by the aid of

the microscope, so close attention to these matters in numberless cases

during many years, has proved beyond a doubt that the gaol distemper,

putrid fever, plague, and infectious epidemics generally, proceed not

from matter putrid in itself, but from invisible insects also, that,

floating in the air at times, are lodged in the skin in immense

quantities; feeding here in clusters, they produce pimples, pustules,

etc.; for instance, the eruption of small-pox. He overlooks, or fails to

mention, the possibility of their entering by the air passages or

digestive system. “Medicines,” he says, “which poison insects without

injuring the constitution have always proved specific.” These insects,

which constitute contagion, are communicated by air, the raiment, as by

contact. He admits that vegetables as well as animals suffer from the

ravages of these animalcules. He believed that they originated from eggs

and not _de novo_. He advises fumigations with sulphur and frankincense

to destroy contagion in rooms, and shows that many diseases in lower

animals are cured or prevented by the use of certain agents known to

kill insects.

In summing up his theory, he says that, generally speaking, there are

two sources of these animalcules. First, from subterranean sources,

which operate in all sorts of weather and are accompanied by electrical

phenomena. Second, from the surface of the earth, swamps, filthy lakes,

stagnant ponds, etc. The eggs left on the soil develop in summer, and

“the multitudes effluviate into air.”

The essay is interesting to us because of the very clear foreshowing of

a theory that we are apt to regard as the creation of recent years. It

is a good example of the power of attentive observation and inductive

reasoning, which is so seldom met with even in scientific medical men of

the present day.

The Brooklyn Medical Journal. Vol. II. No. 2. Aug., 1888 · 第 29 / 75 题