Paralysis Agitans

(SHAKING PALSY)

=Definition.=—A chronic, nervous disease, characterized by tremors,

muscular weakness, muscular rigidity and alterations in the gait.

=Etiology.=—The disease usually commences after forty years of age,

but occasionally it occurs from the thirtieth to fortieth years. It

is more frequent in males than in females. Heredity seems to have but

little influence in the cause of the disease. Among the principal

causes are physical injuries, exposure to cold and wet, emotion, worry,

alcoholism, sexual excesses and acute diseases. Physical injury,

in conjunction with exposure to cold is the best determined cause.

Disorder of the vertebræ of the cervical or dorsal regions, or of the

upper and middle ribs, can generally be found. Traumatic influences

probably affect the nerve centers, causing a disturbed innervation,

either by the direct effect of the deranged structures upon the nervous

tissues or obstructing nutritive channels to the nervous tissues.

In most cases no changes have been observed in the central nervous

system or in the sympathetic ganglia. Some observers have noted

induration of the pons, medulla and cord, but these changes may be due

to senility or to the indirect consequences of the long disturbance

of function. In a few cases, interstitial sclerosis of the peripheral

nerves is observed; these are probably secondary changes. Osteopathic

experience regards paralysis agitans as an affection of the central

nervous system, due to a disordered structure in the locality affected.

=Symptoms.=—The onset is usually gradual, but may come on quite

suddenly after exertion. The =initial= symptoms are usually tremor,

stiffness or weakness in one hand. In rare cases, at first there may

be neuralgic pains, dizziness and symptoms of a rheumatoid nature. The

tremor can be controlled by the will at the onset of the disease. The

affection gradually extends until an entire side or the upper or lower

limbs are involved. At this =advanced stage= of the disease, a peculiar

muscular rigidity of the involved region takes place. Muscular weakness

comes on at about the same time as the rigidity, and the loss of power

varies much in degree. The condition is most marked in the fingers and

hands, whence it extends to the arms and legs. It commonly passes from

the right arm to the right leg, then to the left arm, and then to the

left leg. At this stage the movement between the thumb and fingers is

like that of crumbling bread. The writing is greatly affected and in

time it is impossible to write. The trembling may be so violent as to

prevent sleeping. There is occasionally an intermission of days in the

tremor.

On account of the rigidity of the muscles, the patient assumes a

characteristic =attitude= and =gait=. The position of the body is

that of a tendency to go forward, the head is bent forward, the back

curved outward, the arm bent at the elbow and held away from the body,

and the knees so close together that they rub in walking. The gait

is a “propulsive” one, and when once started in a forward walk, the

patient’s gait becomes more and more rapid and he cannot stop until

he comes against some object. The expression of the face is stiff and

mask-like, the speech slow and monotonous and the voice shrill. The

patient is generally restless and troubled with insomnia. The general

health is in fairly good condition. Reflexes are usually normal. The

intellect is generally retained, although the physical ailment may

cause mental depression.

=Diagnosis.=—Is usually easy and can oftentimes be made at a glance.

=Disseminated sclerosis= has a tremor, but is shown particularly in

voluntary movements. The speech is scanning and the gait ataxic. The

disease begins in the lower extremities, the attitude is different

from that of paralysis agitans, and there is nystagmus. In =chorea=

the movements are general, irregular and more intermittent, and it

particularly involves muscles of the face. Also chorea is a disease of

children and young adults.

The =tremors= of old age, hysteria, and certain toxic conditions due to

tobacco, alcohol, etc. are generally easily diagnosed.

=Prognosis.=—The disease does not necessarily shorten life; the patient

oftentimes dies with some intercurrent disease. Improvement usually

results from careful, prolonged treatment. Early treatment, of course,

will give the most satisfactory results, and occasionally, if taken

very early, the case can be cured.

=Treatment.=—A most careful examination of the physical structures of

the patient should be made, particular attention being paid to the

=cervical= and =dorsal vertebræ=, the upper and middle =ribs= and the

=muscles= along the spinal column. All irregularities found should be

corrected if possible, and strong, thorough treatment given to the

region of innervation of the affected parts. Traction of the rigid

areas is of some value. Treatment of the arms and legs will also be of

aid. All mental strain and physical exhaustion should be prevented if

possible. General =hygienic measures= are to be employed. The life of

the patient should be quiet and regular. Bathing, fresh air, massage

and outdoor life will aid in improving the general health. =Persistent=

treatment will retard the progress and frequently improve the general

condition. Simple and hysterical tremor must not be confounded with

that of paralysis agitans. E. Ashmore[119] reports an interesting case

which shows about what may be expected under treatment.

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