Chlorosis

(GREEN SICKNESS)

An anemia characterized by great reduction in the amount of hemoglobin.

It most frequently occurs in adolescent girls. It seems to be

associated with neurotic manifestations and menstrual irregularities.

=Etiology.=—Its cause is not well understood. Poor hygienic conditions

may be a factor, but it is a condition found in all stations of

life. The age and sex have led to investigation as to probability of

lack of an ovarian internal secretion. The reports of workers are

contradictory. The name of the condition is derived from the color of

the skin, which usually ranges from a pale greenish tint to a slight

pallor. Occasionally there is localized vasodilation of the cheeks

giving brilliant color. Constipation accompanied by copremia seems to

be either a causative factor or result. In many cases it appears to act

in the dual role. Fixation of the middle and lower ribs accompanied by

osteopathic lesions from the mid to the lower dorsal spine seem to be

constant findings. The costal fixation leads to lessened respiratory

excursion and resulting diminished oxygenation.

=Diagnosis.=—Chlorosis may be suspected from the color of the skin,

perverted appetite, wandering neuralgias, heart palpitation, edematous

infiltration, and shallow type respiration, but the diagnosis is not to

be made without the aid of the blood count. The striking part of the

blood picture is the great reduction in amount of hemoglobin carried by

each erythrocyte. There is usually some reduction in the erythrocyte

percentage but not in proportion to the decrease in color index.

There are usually many pessary-shaped and shadow erythrocytes. These

are of all sizes, but seldom is the condition of such gravity as to

cause more than an occasional nucleated red cell, and when found

are most likely to be normoblasts. The staining reaction is of wide

limits. Cells of all degrees of relative alkalinity are found and often

there is a wide variation of staining reaction in the same cell. The

number of erythrocytes is usually slightly decreased but not in the

proportion that the hemoglobin percentage is, so that the color index

is therefore strikingly low. Probably, the average color index for a

typical case of chlorosis is 50, with an erythrocyte count of 4,000,000

and a hemoglobin of 40 per cent (Dare.) This drop in color index in

chlorosis is far out of proportion to the clinical symptoms which would

be expected from a similar reduction resulting from the ordinary causes

of secondary anemia. The blood plasma is increased and the specific

gravity is lowered, sometimes reduced from 1.055 to about 1.030.

=Treatment.=—The treatment of any malady in which the etiology may

be apparently of widely different natures will naturally rationally

vary with the apparent cause. If there is copremia, which seems to be

a definite causative factor, this should be at once corrected. These

patients form the cathartic habit readily, so physical and dietary

methods of returning the digestive motility to normal should logically

be given first trial. If it is a matter of lessened metabolism as

a result of insufficient exercise, or blood oxygenation, outdoor

gymnastics and breathing exercises may incite the stimulus to normal

erythrocyte hemoglobinization. The diet should be of such nature as

to furnish material both for erythrocyte formation and iron in form

for ready absorption by them. The organic iron compounds of animal

hemoglobin and vegetable chlorophyl are our most common and cheapest as

well as most effective sources.

The medical treatment of chlorosis is based on the empiric use of

inorganic iron. “The exact method in which iron exerts a favorable

influence upon chlorosis still remains unsettled. It is difficult to

understand why iron salts in the food which are sufficient for all

ordinary needs, are insufficient in chlorosis. It seems most probable

that iron cures chlorosis by acting as a stimulant to the =blood

forming organs=” (Beifeld, The Basis of Symptoms.)

Clinically, osteopaths are daily obtaining rationally the necessary

stimulus to the blood forming organs by removing all impedance from

these organs caused by vertebral and costal lesions and by obtaining

better digestive and respiratory hygiene.

=Prognosis.=—Recovery is to be expected and its rate will depend upon

the thoroughness of the osteopathic work and the patient’s ability to

respond to the stimulus. The blood may show chlorotic relapses with

concomitant symptoms if in later life secondary anemia develops from

hemorrhage, hook-worm infection, or other causes.

The practice of osteopathy · 第 437 / 511 题