ON THE MEDICINAL PROPERTIES OF MAGNESIA ALBA.

The medicinal uses to which Magnesia has hitherto been applied are in

general so well known, that it will be necessary only to give a short

summary of the cases in which it is beneficial, for the information

of young practitioners, and of those of my readers who may not be

acquainted with medical subjects, this medicine being frequently

administered without the advice of a physician. If it should appear in

the subsequent part of this treatise that Magnesia is possessed of any

properties hitherto unsuspected in it, the sagacious reader will in a

great measure be left to draw his own practical inferences therefrom.

MAGNESIA ALBA is a powerful absorbent, and is given with great

success in disorders of the stomach and bowels arising from acidity.

This preparation had been introduced into the materia medica abroad

several years before it attracted the attention of our countrymen. The

celebrated Hoffman having strongly recommended it to the medical world,

some English practitioners began to prescribe it, and Dr. Cadogan

bestowing high encomiums on it, in his treatise on the nursing and

management of children, it soon made its way into general practice, and

supplied the place of the testaceous powders and chalk, which before

this period were the medicines usually given to correct acidities

in the primæ viæ. The acquisition of this medicine was of the more

importance, on account of its entire and easy solution in acids, and of

the purgative quality which it possesses; whereas the common absorbents

are apt to form concretions, and to induce costiveness; strong

objections to their free exhibition, as these properties render them

peculiarly unfit for the bowels of tender infants who are particularly

liable to diseases of this class.

This tendency to acidity generally attends children during the first

months and the time of dentition, and discovers itself when too

redundant by the green stools, sour vomitings, gripes and purgings

which it occasions: and as the nerves of children are extremely

irritable, spasmodic affections are often the consequence of this acrid

stimulus being retained in their bowels. In these cases Magnesia may be

administered in doses from five to twenty or thirty grains, according

to the age of the infant; and in proportion as it is intended to act,

either as an alterative, or as an easy purgative.

It has been a common practice to give Magnesia to children as a

preventive, and to mix it for this purpose with their food, in order

to correct that disposition which milk and the farinaceous aliments

have to turn sour. This however should be done with caution, for it

is only the excess of acidity which is prejudicial to infants,[l] some

degree of it is necessary; and should we too officiously and entirely

destroy, what we ought only to restrain within due bounds, we may

create disorders of an opposite nature to those we have endeavoured to

prevent, and instead of an acid, produce an alkalescent disposition

in the first passages. Indeed I fear that diseases have been more

frequently created than obviated by the use of preventive medicines,

and they should only be allowed in cases where the approach to disease

is manifest. But when a child is in a healthy state, the best means to

preserve him from a superabundant acidity, is to pay due attention to

the regulation of his diet, to give him proper exercise, not to confine

him too much in the foul air of hot unventilated rooms, to wash his

whole body every day in cold water, and to rub him very well night and

morning with a dry flannel, taking care that his stomach be not too

full at the time when this friction is performed.

[l] Hactenus monstravimus, sicut cordis, musculorumque vires debiles

erant, ita et solidorum quoque statum necessario imbecillem fuisse, et

succos tenues, dilutosque; ut natura ampliationem vasculorum facilius

efficeret, et incrementum animale minori cum molestiâ perageret.

Sed ne status iste tonusque partium debilis laxusque ultra modum

procederet (quod sæpe accidit, morbosque excitare solet) acidum quoddam

juvenilium animalium stomachis datum est, quod quamvis aluminis

instar, lac coagulat, atque ob eam causam aliquando morbum procreat,

tamen fibrarum tonum astringet confirmatque, et putredinem omnem

alkalinam, a qua alioquin periculum esset, reprimit. Quod quidem

videri est, vel in coagulo stomachi vitulini, vel in aliis animalibus:

sed istud tamen acidum, quod infantibus tarn idoneum est, redundat

fortasse nonnumquam, et vel per testaceas pulveres, vel per medicamenta

antiacida, ut supra dixi, corrigi debet.

Russelli OEconomia Naturæ, p. 56.

Nor would I advise parents to rely with too much security on the

virtues of this medicine, where the disorders of their children

are complicated, or obstinate. The advice of the sagacious and

distinguishing practitioner will then be necessary to direct what

method of treatment is to be pursued. Nor can I here avoid lamenting

that the management of children when diseased, is so often in the hands

of nurses and ignorant women, from an absurd notion that their diseases

are not proper subjects of medical investigation; when in truth, there

are none which require a clearer judgement, a quicker penetration, or a

greater share of medical knowledge in the prescriber.

During the period between dentition and puberty, the diseases attendant

on a lax fibre still continue, though not so predominantly as in the

former stage; yet acescency is the manifest cause, or at least the

concomitant of many of the complaints to which children are at this

time liable. To this they are disposed, notwithstanding the change

in their diet to a more alkalescent kind, by the great quantities

of fruit, frequently crude and unripe, cakes, and other sweet and

greasy food with which they are too often indulged. By these errors

their bowels are overcharged, their digestion impaired, and the

aliment remaining too long in the stomach becomes sour, and occasions

vomitings, head achs, and other complaints which are often thought

to proceed from worms, and indeed are frequently attended with that

disorder; as the crudities thus generated in the bowels serve as a

nidus for these destructive vermin. Here likewise Magnesia may be of

considerable advantage as an alkaline purgative, neutralizing the

offending acid, and at the same time promoting its discharge by stool.

But if the stomach be overloaded with mucus or undigested aliment, a

gentle vomit ought to precede the exhibition of the Magnesia.

And even in a more advanced stage of life, persons of weak habits, and

who lead sedentary lives, are often afflicted with indigestion, sour

eructations, heart-burn, vomitings, and costiveness. These disorders

very frequently attend women during their state of pregnancy, and

are sometimes almost instantly removed by the use of Magnesia. Dr.

Watson[m] has published the case of a pregnant woman, who was afflicted

with such severe vomitings as to bring on convulsions, hiccoughing, and

violent pain at her stomach. What she brought up was acid, and so very

acrimonious, as to inflame and excoriate her mouth and throat; and the

great uneasiness she felt at her stomach upon swallowing any liquor

that had the least degree of acrimony, or was more than lukewarm, made

it probable that the internal surface of the stomach was affected

in the same manner. In this desperate situation, after a variety

of remedies had been tried in vain, the stomach was washed with

unsalted mutton broth, till the liquor was discharged without any acid

taste. Her pain was by this means abated, but in about two hours was

apparently returning with the same violence as before. This ingenious

Physician then directed a drachm of Magnesia to be given in mutton

broth, and to be repeated as often as her pain returned, without any

regard to the quantity the whole might amount to, supposing her pain

to continue severe. The first dose relieved her, and in three days she

took three ounces of Magnesia; and in the next three days, two ounces

more, by which time all her symptoms were removed. It is remarkable

in this case that a hypercatharsis was not the consequence of taking

so large a quantity of Magnesia, where there was so much acid to

neutralize it.

[m] Medical Observations and Inquiries, Vol. III. p. 335.

In bilious habits, where there is generally a disposition in the

stomach contrary to acidity, Magnesia is usually esteemed to be

improper, taken alone: but I am dubious whether this opinion is well

founded, and many reasons for these doubts may be deduced from the

experiments hereafter to be recited. However, where putrid bile is to

be corrected and discharged, by stool, very good purposes may, perhaps,

be answered by taking the Magnesia, joined with a sufficient quantity

of acid to neutralize it, while in a state of effervescence; or by

swallowing the Magnesia and the acid, one immediately after the other,

so as to produce the fermentation in the stomach: for thus the fixed

air with which the Magnesia so greatly abounds, being let loose, may

powerfully correct the tendency to putridity in the contents of the

primæ viæ, and at the same time evacuate them downwards.

How far Magnesia may be of service in diseases of the skin I do not

take upon me to determine. Several authors have attributed cutaneous

eruptions, and indeed the ancient chemists ascribed almost all

disorders, to the presence of an acid in the blood; whilst others

absolutely deny that an acid can be admitted into the lacteals, or,

if admitted, exist in the blood in a state of acidity. In these cases

however, if an acid acrimony abounds in the stomach and bowels, with

a costive habit, and pale complexion, Magnesia will be a useful

corrector, and entering into the circulation in the form of a mild

neutral salt, may act as an excellent alterative,[n] proving both

diaphoretic and diuretic.

Having thus given a cursory detail of the medicinal properties of

Magnesia, in its natural state, I shall now proceed to consider it

in a state of calcination: but before any description of its uses in

medicine be given, it may be proper to take a view of the changes which

are produced in the nature of it by this operation.

[n] Neque enim tantum absorbentem et catharticam, si acidum primâ in

regione stabulatur, virtutem exserit; verum etiam si in remissiore

dosi, ad grana xv. vel xx. usurpatur, diaphoreticum et diureticum

effectum sequi, non semel observavimus.

Hoffman. circa Magnesiam. Oper. Tom. 4. p. 481.

Experiments and Observations on the Following Subjects 1. On the preparation, calcination, and medicinal uses of Magnesia Alba. 2. On the solvent qualities of calcined Magnesia. 3. On the variety in the solvent powers of quick-lime, when used in different quantities. 4. On various absorbents, as promoting or retarding putrefaction. 5. On the comparative antiseptic powers of vegetable infusions prepared with lime, &c. 6. On the sweetening properties of fixed air. · 第 40 / 93 题