PART I.

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MEDICAL INQUIRIES

AND

OBSERVATIONS.

BY BENJAMIN RUSH, M. D.

PROFESSOR OF THE INSTITUTES AND PRACTICE OF MEDICINE,

AND OF CLINICAL PRACTICE, IN THE UNIVERSITY

OF PENNSYLVANIA.

IN FOUR VOLUMES.

VOL. I.

THE SECOND EDITION,

REVISED AND ENLARGED BY THE AUTHOR.

PHILADELPHIA,

PUBLISHED BY J. CONRAD & CO. CHESNUT-STREET, PHILADELPHIA; M. & J.

CONRAD & CO. MARKET-STREET, BALTIMORE; RAPIN, CONRAD, & CO. WASHINGTON;

SOMERVELL & CONRAD, PETERSBURG; AND BONSAL, CONRAD, & CO. NORFOLK.

PRINTED BY T. & G. PALMER, 116, HIGH-STREET.

1805.

* * * * *

PREFACE.

In this second edition of the following Medical Inquiries and

Observations, the reader will perceive many additions, some omissions,

and a few alterations.

A number of facts have been added to the Inquiry into the Effects of

Ardent Spirits upon the Body and Mind, and to the Observations upon the

Tetanus, Cynanche Trachealis, and Old Age, in the first volume; also to

the Observations upon Dropsies, Pulmonary Consumption, and Hydrophobia,

contained in the second volume.

The Lectures upon Animal Life, which were published, a few years ago, in

a pamphlet, have received no other additions than a few notes.

The phænomena of fever have not only received a new title, but several

new terms have been adopted in detailing them, chiefly to remove the

mistake into which the use of Dr. Brown's terms had led some of the

author's readers, respecting his principles. A new order has likewise

been given, and some new facts added, to the inquiry upon this subject.

In the Account of the Yellow Fever of 1793, many documents, interesting

to the public at the time of their first publication, are omitted; and

many of the facts and observations, which related to the origin of the

fevers of 1794 and 1797, now form a part of a separate inquiry upon that

subject, in the fourth volume.

The histories of the yellow fever as epidemics, and of its sporadic

cases, have been published in the order in which they have appeared

in Philadelphia, to show the influence of the weather upon it, and

the impropriety and danger of applying the same remedies for the same

epidemic, in different and even successive seasons. The records of

the first cases of yellow fever, which have appeared in each of the

twelve years that have been noticed, are intended further to show the

inefficacy of all the means, at present employed, to prevent its future

recurrence.

In the fourth volume, the reader will find a retraction of the author's

former opinion of the yellow fever's spreading by contagion. He begs

forgiveness of the friends of science and humanity, if the publication

of that opinion has had any influence in increasing the misery and

mortality attendant upon that disease. Indeed, such is the pain he

feels, in recollecting that he ever entertained or propagated it, that

it will long, and perhaps always, deprive him of the pleasure he might

otherwise have derived from a review of his attempts to fulfil the

public duties of his profession.

Considerable additions are made to the facts and arguments in favour

of the domestic origin of the yellow fever, and to the Defence of

Blood-letting.

The Account of the Means of Preventing the Usual Forms of Summer and

Autumnal Disease, appears for the first time in this edition of the

author's Inquiries. Part of the facts intended to prove the yellow fever

not to be contagious, were published in the sixth volume of the New-York

Medical Repository. The reader will perceive, among many additions

to them, answers to all the arguments usually employed to defend the

contrary opinion.

The Inquiry into the Comparative State of Medicine, in Philadelphia,

between the years 1760 and 1766, and 1805, was delivered, in the form of

an oration, before the Medical Society of Philadelphia, on the 18th of

February, 1804. Some things have been omitted, and a few added, in the

form in which it is now offered to the public.

If this edition of Medical Inquiries and Observations should be less

imperfect than the former, the reader is requested to ascribe it to

the author having profited by the objections he encouraged his pupils

to make to his principles, in their inaugural dissertations, and in

conversation; and to the many useful facts which have been communicated

to him by his medical brethren, whose names have been mentioned in the

course of the work.

For the departure, in the modes of practice adopted or recommended in

these Inquiries, from those which time and experience have sanctioned,

in European and in East and West-Indian countries, the author makes the

same defence of himself, that Dr. Baglivi made, near a century ago, of

his modes of practice in Rome. "_Vivo et scribo in aere Romano_," said

that illustrious physician. The author has lived and written in the

climate of Pennsylvania, and in the city of Philadelphia.

_November 18th, 1805._

* * * * *

CONTENTS OF VOLUME I.

_page_

_An inquiry into the natural history of medicine among the

Indians of North-America, and a comparative view of their

diseases and remedies with those of civilized nations_ 1

_An account of the climate of Pennsylvania, and its influence

upon the human body_ 69

_An account of the bilious remitting fever, as it appeared in

Philadelphia in the summer and autumn of the year 1780_ 115

_An account of the scarlatina anginosa, as it appeared in

Philadelphia in the years 1783 and 1784_ 135

_An inquiry into the cause and cure of the cholera infantum_ 153

_Observations on the cynanche trachealis_ 167

_An account of the efficacy of blisters and bleeding, in the cure

of obstinate intermitting fevers_ 177

_An account of the disease occasioned by drinking cold water in

warm weather, and the method of curing it_ 181

_An account of the efficacy of common salt in the cure of

hæmoptysis_ 189

_Thoughts on the cause and cure of pulmonary

consumption_ 197

_Observations upon worms in the alimentary canal, and upon

anthelmintic medicines_ 215

_An account of the external use of arsenic in the cure of

cancers_ 235

_Observations on the tetanus_ 245

_The result of observations made upon the diseases which occurred

in the military hospitals of the United States, during the

revolutionary war_ 267

_An account of the influence of the military and political events

of the American revolution upon the human body_ 277

_An inquiry into the relation of tastes and aliments to each

other, and into the influence of this relation upon health and

pleasure_ 295

_The new method of inoculating for the small-pox_ 309

_An inquiry into the effects of ardent spirits upon the human

body and mind, with an account of the means of preventing, and

the remedies for curing them_ 335

_Observations on the duties of a physician, and the methods of

improving medicine; accommodated to the present state of society

and manners in the United States_ 385

_An inquiry into the causes and cure of sore legs_ 401

_An account of the state of the body and mind in old age, with

observations on its diseases, and their remedies_ 425

* * * * *

AN INQUIRY

INTO THE

_NATURAL HISTORY OF MEDICINE_

AMONG THE

INDIANS OF NORTH-AMERICA;

AND A

COMPARATIVE VIEW

OF THEIR

DISEASES AND REMEDIES WITH THOSE OF

CIVILIZED NATIONS.

Read before the AMERICAN PHILOSOPHICAL SOCIETY, held at

PHILADELPHIA, on the 4th of February, 1774.

GENTLEMEN[1],

I rise with peculiar diffidence to address you upon this occasion,

when I reflect upon the entertainment you proposed to yourselves from

the eloquence of that learned member, Mr. CHARLES THOMPSON, whom your

suffrages appointed to this honour after the delivery of the last

anniversary oration. Unhappily for the interests of science, his want

of health has not permitted him to comply with your appointment. I beg,

therefore, that you would forget, for a while, the abilities necessary

to execute this task with propriety, and listen with candour to the

efforts of a member, whose attachment to the society was the only

qualification that entitled him to the honour of your choice.

[1] This INQUIRY was the subject of an Anniversary Oration. The style

of an oration is therefore preserved in many parts of it.

The subject I have chosen for this evening's entertainment, is "An

inquiry into the natural history of medicine among the Indians in

North-America, and a comparative view of their diseases and remedies,

with those of civilized nations." You will readily anticipate the

difficulty of doing justice to this subject. How shall we distinguish

between the original diseases of the Indians and those contracted from

their intercourse with the Europeans? By what arts shall we persuade

them to discover their remedies? And lastly, how shall we come at the

knowledge of facts in that cloud of errors, in which the credulity

of the Europeans, and the superstition of the Indians, have involved

both their diseases and remedies? These difficulties serve to increase

the importance of our subject. If I should not be able to solve them,

perhaps I may lead the way to more successful endeavours for that

purpose.

I shall first limit the tribes of Indians who are to be the objects of

this inquiry, to those who inhabit that part of North-America which

extends from the 30th to the 60th degree of latitude. When we exclude

the Esquimaux, who inhabit the shores of Hudson's bay, we shall find a

general resemblance in the colour, manners, and state of society, among

all the tribes of Indians who inhabit the extensive tract of country

above-mentioned.

Civilians have divided nations into savage, barbarous, and civilized.

The savage live by fishing and hunting; the barbarous, by pasturage or

cattle; and the civilized, by agriculture. Each of these is connected

together in such a manner, that the whole appear to form different parts

of a circle. Even the manners of the most civilized nations partake of

those of the savage. It would seem as if liberty and indolence were

the highest pursuits of man; and these are enjoyed in their greatest

perfection by savages, or in the practice of customs which resemble

those of savages.

The Indians of North-America partake chiefly of the manner of savages.

In the earliest accounts we have of them, we find them cultivating a

spot of ground. The maize is an original grain among them. The different

dishes of it which are in use among the white people still retain Indian

names.

It will be unnecessary to show that the Indians live in a state of

society adapted to all the exigencies of their mode of life. Those who

look for the simplicity and perfection of the state of nature, must

seek it in systems, as absurd in philosophy, as they are delightful in

poetry.

Before we attempt to ascertain the number or history of the diseases of

the Indians, it will be necessary to inquire into those customs among

them which we know influence diseases. For this purpose I shall,

First, Mention a few facts which relate to the birth and treatment of

their children.

Secondly, I shall speak of their diet.

Thirdly, Of the customs which are peculiar to the sexes, and,

Fourthly, Of those customs which are common to them both[2].

[2] Many of the facts contained in the Natural History of Medicine

among the Indians in this Inquiry, are taken from La Hontan and

Charlevoix's histories of Canada; but the most material of them

are taken from persons who had lived or travelled among the

Indians. The author acknowledges himself indebted in a particular

manner to Mr. Edward Hand, surgeon in the 18th regiment,

afterwards brigadier-general in the army of the United States,

who, during several years' residence at Fort Pitt, directed his

inquiries into their customs, diseases, and remedies, with a

success that does equal honour to his ingenuity and diligence.

I. Of the birth and treatment of their children.

Much of the future health of the body depends upon its original stamina.

A child born of healthy parents always brings into the world a system

formed by nature to resist the causes of diseases. The treatment of

children among the Indians, tends to secure this hereditary firmness of

constitution. Their first food is their mother's milk. To harden them

against the action of heat and cold (the natural enemies of health and

life among the Indians) they are plunged every day into cold water. In

order to facilitate their being moved from place to place, and at the

same time to preserve their shape, they are tied to a board, where they

lie on their backs for six, ten, or eighteen months. A child generally

sucks its mother till it is two years old, and sometimes longer. It is

easy to conceive how much vigour their bodies must acquire from this

simple, but wholesome nourishment. The appetite we sometimes observe in

children for flesh is altogether artificial. The peculiar irritability

of the system in infancy forbids stimulating aliment of all kinds.

Nature never calls for animal food till she has provided the child with

those teeth which are necessary to divide it. I shall not undertake

to determine how far the wholesome quality of the mother's milk is

increased by her refusing the embraces of her husband, during the time

of giving suck.

II. The diet of the Indians is of a mixed nature, being partly animal

and partly vegetable. Their animals are wild, and therefore easy of

digestion. As the Indians are naturally more disposed to the indolent

employment of fishing than hunting, in summer, so we find them living

more upon fish than land animals, in that season of the year.--Their

vegetables consist of roots and fruits, mild in themselves, or capable

of being made so by the action of fire. Although the interior parts

of our continent abound with salt springs, yet I cannot find that the

Indians used salt in their diet, till they were instructed to do so by

the Europeans. The small quantity of fixed alkali contained in the ashes

on which they roasted their meat, could not add much to its stimulating

quality. They preserve their meat from putrefaction, by cutting it into

small pieces, and exposing it in summer to the sun, and in winter to

the frost. In the one case its moisture is dissipated, and in the other

so frozen, that it cannot undergo the putrefactive process. In dressing

their meat, they are careful to preserve its juices. They generally

prefer it in the form of soups. Hence we find, that among them the use

of the spoon, preceded that of the knife and fork. They take the same

pains to preserve the juice of their meat when they roast it, by turning

it often. The efficacy of this animal juice, in dissolving meat in the

stomach, has not been equalled by any of those sauces or liquors which

modern luxury has mixed with it for that purpose.

The Indians have no set time for eating, but obey the gentle appetites

of nature as often as they are called by them. After whole days spent

in the chace or in war, they often commit those excesses in eating, to

which long abstinence cannot fail of prompting them. It is common to

see them spend three or four hours in satisfying their hunger. This is

occasioned not more by the quantity they eat, than by the pains they

take in masticating it. They carefully avoid drinking water in their

marches, from an opinion that it lessens their ability to bear fatigue.

III. We now come to speak of those customs which are peculiar to the

sexes. And, first, of those which belong to the WOMEN. They are doomed

by their husbands to such domestic labour as gives a firmness to their

bodies, bordering upon the masculine. Their menses seldom begin to

flow before they are eighteen or twenty years of age, and generally

cease before they are forty. They have them in small quantities, but at

regular intervals. They seldom marry till they are about twenty. The

constitution has now acquired a vigour, which enables it the better to

support the convulsions of child-bearing. This custom likewise guards

against a premature old age. Doctor Bancroft ascribes the haggard looks,

the loose hanging breasts, and the prominent bellies of the Indian

women at Guiana, entirely to their bearing children too early[3]. Where

marriages are unfruitful (which is seldom the case) a separation is

obtained by means of an easy divorce; so that they are unacquainted

with the disquietudes which sometimes arise from barrenness. During

pregnancy, the women are exempted from the more laborious parts of their

duty: hence miscarriages rarely happen among them. Nature is their only

midwife. Their labours are short, and accompanied with little pain. Each

woman is delivered in a private cabin, without so much as one of her

own sex to attend her. After washing herself in cold water, she returns

in a few days to her usual employments; so that she knows nothing of

those accidents which proceed from the carelessness or ill management

of midwives; or those weaknesses which arise from a month's confinement

in a warm room. It is remarkable that there is hardly a period in the

interval between the eruption and the ceasing of the menses, in which

they are not pregnant, or giving suck. This is the most natural state

of the constitution during that interval; and hence we often find it

connected with the best state of health, in the women of civilized

nations.

[3] Natural History of Guiana.

The customs peculiar to the Indian MEN, consist chiefly in those

employments which are necessary to preserve animal life, and to defend

their nation. These employments are hunting and war, each of which

is conducted in a manner that tends to call forth every fibre into

exercise, and to ensure them the possession of the utmost possible

health. In times of plenty and peace, we see them sometimes rising from

their beloved indolence, and shaking off its influence by the salutary

exercises of dancing and swimming. The Indian men seldom marry before

they are thirty years of age: they no doubt derive considerable vigour

from this custom; for while they are secured by it from the enervating

effects of the premature dalliance of love, they may insure more certain

fruitfulness to their wives, and entail more certain health upon

their children. Tacitus describes the same custom among the Germans,

and attributes to it the same good effects. "Sera juvenum venus, eoque

inexhausta pubertas; nec virgines festinantur; eadem juventa, similis

proceritas, pares validique miscentur; ac robora parentum liberi

referunt[4]."

[4] Cæsar, in his history of the Gallic war, gives the same account

of the ancient Germans. His words are "Qui diutissimi impuberes

permanserunt, maximam inter suos ferunt laudem: hoc ali staturam,

ali vires, nervasque confirmari putant." Lib. vi. xxi.

Among the Indian men, it is deemed a mark of heroism to bear the most

exquisite pain without complaining; upon this account they early inure

themselves to burning part of their bodies with fire, or cutting them

with sharp instruments. No young man can be admitted to the honours of

manhood or war, who has not acquitted himself well in these trials of

patience and fortitude. It is easy to conceive how much this contributes

to give a tone to the nervous system, which renders it less subject to

the occasional causes of diseases.

IV. We come now to speak of those customs which are common to both

sexes: these are PAINTING, and the use of the COLD BATH. The practice

of anointing the body with oil is common to the savages of all

countries; in warm climates it is said to promote longevity, by checking

excessive perspiration. The Indians generally use bear's grease mixed

with a clay, which bears the greatest resemblance to the colour of their

skins. This pigment serves to lessen the sensibility of the extremities

of the nerves; it moreover fortifies them against the action of those

exhalations, which we shall mention hereafter, as a considerable source

of their diseases. The COLD BATH likewise fortifies the body, and

renders it less subject to those diseases which arise from the extremes

and vicissitudes of heat and cold. We shall speak hereafter of the

Indian manner of using it.

It is a practice among the Indians never to drink before dinner, when

they work or travel. Experience teaches, that filling the stomach with

cold water in the forenoon, weakens the appetite, and makes the system

more sensible of heat and fatigue.

The state of society among the Indians excludes the influence of most of

those passions which disorder the body. The turbulent effects of anger

are concealed in deep and lasting resentments. Envy and ambition are

excluded by their equality of power and property. Nor is it necessary

that the perfections of the whole sex should be ascribed to one, to

induce them to marry. "The weakness of love (says Dr. Adam Smith) which

is so much indulged in ages of humanity and politeness, is regarded

among savages as the most unpardonable effeminacy. A young man would

think himself disgraced for ever, if he showed the least preference

of one woman above another, or did not express the most complete

indifference, both about the time when, and the person to whom, he was

to be married[5]." Thus are they exempted from those violent or lasting

diseases, which accompany the several stages of such passions in both

sexes among civilized nations.

[5] Theory of Moral Sentiments.

It is remarkable that there are no deformed Indians. Some have

suspected, from this circumstance, that they put their deformed children

to death; but nature here acts the part of an unnatural mother. The

severity of the Indian manners destroy them[6].

[6] Since the intercourse of the white people with the Indians, we find

some of them deformed in their limbs. This deformity, upon

inquiry, appears to be produced by those accidents, quarrels, &c.

which have been introduced among them by spiritous liquors.

From a review of the customs of the Indians, we need not be surprised at

the stateliness, regularity of features, and dignity of aspect by which

they are characterized. Where we observe these among ourselves, there

is always a presumption of their being accompanied with health, and a

strong constitution. The circulation of the blood is more languid in the

Indians, than in persons who are in the constant exercise of the habits

of civilized life. Out of eight Indian men whose pulses I once examined

at the wrists, I did not meet with one in whom the artery beat more than

sixty strokes in a minute.

The marks of old age appear more early among Indian, than among

civilized nations.

Having finished our inquiry into the physical customs of the Indians, we

shall now proceed to inquire into their diseases.

A celebrated professor of anatomy has asserted, that we could not tell,

by reasoning _à priori_, that the body was mortal, so intimately woven

with its texture are the principles of life. Lord Bacon declares, that

the only cause of death which is natural to man, is that from old

age; and complains of the imperfection of physic, in not being able

to guard the principle of life, until the whole of the oil that feeds

it is consumed. We cannot as yet admit this proposition of our noble

philosopher. In the inventory of the grave in every country, we find

more of the spoils of youth and manhood than of age. This must be

attributed to moral as well as physical causes.

We need only recollect the custom among the Indians, of sleeping in the

open air in a variable climate; the alternate action of heat and cold

upon their bodies, to which the warmth of their cabins exposes them;

their long marches; their excessive exercise; their intemperance in

eating, to which their long fasting and their public feasts naturally

prompt them; and, lastly, the vicinity of their habitations to the banks

of rivers, in order to discover the empire of diseases among them in

every stage of their lives. They have in vain attempted to elude the

general laws of mortality, while their mode of life subjects them to

these remote, but certain causes of diseases.

From what we know of the action of these powers upon the human body,

it will hardly be necessary to appeal to facts to determine that

FEVERS constitute the only diseases among the Indians. These fevers

are occasioned by the insensible qualities of the air. Those which

are produced by cold and heat are of the inflammatory kind, such as

pleurisies, peripneumonies, and rheumatisms. Those which are produced

by the insensible qualities of the air, or by putrid exhalations, are

intermitting, remitting, inflammatory, and malignant, according as the

exhalations are combined with more or less heat or cold. The DYSENTERY

(which is an Indian disease) comes under the class of fevers. It appears

to be the febris introversa of Dr. Sydenham.

The Indians are subject to ANIMAL and VEGETABLE POISONS. The effects of

these upon the body, are in some degree analogous to the exhalations we

have mentioned. When they do not bring on sudden death, they produce,

according to their force, either a common inflammatory, or a malignant

fever.

The SMALL POX and the VENEREAL DISEASE were communicated to the Indians

of North-America by the Europeans. Nor can I find that they were ever

subject to the SCURVY. Whether this was obviated by their method

of preserving their flesh, or by their mixing it at all times with

vegetables, I shall not undertake to determine. Their peculiar customs

and manners seem to have exempted them from this, as well as from the

common diseases of the skin.

I have heard of two or three cases of the GOUT among the Indians, but

it was only among those who had learned the use of rum from the white

people. A question naturally occurs here, and that is, why does not the

gout appear more frequently among that class of people, who consume the

greatest quantity of rum among ourselves? To this I answer, that the

effects of this liquor upon those enfeebled people, are too sudden and

violent, to admit of their being thrown upon the extremities; as we know

them to be among the Indians. They appear only in visceral obstructions,

and a complicated train of chronic diseases. Thus putrid miasmata

are sometimes too strong to bring on a fever, but produce instant

debility and death. The gout is seldom heard of in Russia, Denmark, or

Poland. Is this occasioned by the vigour of constitution peculiar to

the inhabitants of those northern countries? or is it caused by their

excessive use of spirituous liquors, which produce the same chronic

complaints among them, which we said were common among the lower class

of people in this country? The similarity of their diseases makes the

last of these suppositions the most probable. The effects of wine, like

tyranny in a well formed government, are felt first in the extremities;

while spirits, like a bold invader, seize at once upon the vitals of the

constitution.

After much inquiry, I have not been able to find a single instance of

FATUITY among the Indians, and but few instances of MELANCHOLY and

MADNESS; nor can I find any accounts of diseases from WORMS among them.

Worms are common to most animals; they produce diseases only in weak,

or increase them in strong constitutions[7]. Hence they have no place

in the nosological systems of physic. Nor is DENTITION accompanied by

disease among the Indians. The facility with which the healthy children

of healthy parents cut their teeth among civilized nations, gives us

reason to conclude that the Indian children never suffer from this

quarter.

[7] Indian children are not exempted from worms. It is common with the

Indians, when a fever in their children is ascribed by the white

people to worms (from their being discharged occasionally in their

stools), to say, "the fever makes the worms come, and not the

worms the fever."

The Indians appear moreover to be strangers to diseases and pains in the

teeth.

The employments of the Indians subject them to many accidents; hence we

sometimes read of WOUNDS, FRACTURES, and LUXATIONS among them.

Having thus pointed out the natural diseases of the Indians, and shown

what diseases are foreign to them, we may venture to conclude, that

FEVERS, OLD AGE, CASUALTIES, and WAR are the only natural outlets

of human life. War is nothing but a disease; it is founded in the

imperfection of political bodies, just as fevers are founded on the

weakness of the animal body. Providence in these diseases seems to act

like a mild legislature, which mitigates the severity of death, by

inflicting it in a manner the least painful, upon the whole, to the

patient and the survivors.

Let us now inquire into the REMEDIES of the Indians. These, like

their diseases, are simple, and few in number. Among the first of

them we shall mention the POWERS OF NATURE. Fevers, we said formerly,

constituted the chief of the diseases among the Indians; they are

likewise, in the hands of nature, the principal instruments to remove

the evils which threaten her dissolution; but the event of these efforts

of nature, no doubt, soon convinced the Indians of the danger of

trusting her in all cases; and hence, in the earliest accounts we have

of their manners, we read of persons who were intrusted with the office

of physicians.

It will be difficult to find out the exact order in which the Indian

remedies were suggested by nature or discovered by art; nor will it be

easy to arrange them in proper order. I shall, however, attempt it, by

reducing them to NATURAL and ARTIFICIAL.

To the class of NATURAL REMEDIES belongs the Indian practice of

abstracting from their patients all kinds of stimulating aliment. The

compliance of the Indians with the dictates of nature, in the early

stage of a disease, no doubt, prevents, in many cases, their being

obliged to use any other remedy. They follow nature still closer, in

allowing their patients to drink plentifully of cold water; this being

the only liquor a patient calls for in a fever.

Sweating is likewise a natural remedy. It was probably suggested by

observing fevers to be terminated by it. I shall not inquire how far

these sweats are essential to the crisis of a fever. The Indian mode of

procuring this evacuation is as follows: the patient is confined in

a close tent, or wigwam, over a hole in the earth, in which a red hot

stone is placed; a quantity of water is thrown upon this stone, which

instantly involves the patient in a cloud of vapour and sweat; in this

situation he rushes out, and plunges himself into a river, from whence

he retires to his bed. If the remedy has been used with success, he

rises from his bed in four and twenty hours, perfectly recovered from

his indisposition. This remedy is used not only to cure fevers, but

remove that uneasiness which arises from fatigue of body.

A third natural remedy among the Indians, is PURGING. The fruits of the

earth, the flesh of birds, and other animals feeding upon particular

vegetables, and, above all, the spontaneous efforts of nature, early led

the Indians to perceive the necessity and advantages of this evacuation.

VOMITS constitute their fourth natural remedy. They were probably, like

the former, suggested by nature, and accident. The ipecacuanha is one of

the many roots they employ for that purpose.

The ARTIFICIAL REMEDIES made use of by the Indians, are BLEEDING,

CAUSTICS, and ASTRINGENT medicines. They confine bleeding entirely to

the part affected. To know that opening a vein in the arm, or foot,

would relieve a pain in the head or side, supposes some knowledge of the

animal economy, and therefore marks an advanced period in the history of

medicine.

Sharp stones and thorns are the instruments they use to procure a

discharge of blood.

We have an account of the Indians using something like a POTENTIAL

CAUSTIC, in obstinate pains. It consists of a piece of rotten wood

called _punk_, which they place upon the part affected, and afterwards

set it on fire: the fire gradually consumes the wood, and its ashes burn

a hole in the flesh.

The undue efforts of nature, in those fevers which are connected with

a diarrh[oe]a, or dysentery, together with those hemorrhages to which

their mode of life exposed them, necessarily led them to an early

discovery of some ASTRINGENT VEGETABLES. I am uncertain whether the

Indians rely upon astringent, or any other vegetables, for the cure of

the intermitting fever. This disease among them probably requires no

other remedies than the cold bath, or cold air. Its greater obstinacy,

as well as frequency, among ourselves, must be sought for in the

greater feebleness of our constitutions, and in that change which our

country has undergone, from meadows, mill-dams, and the cutting down

of woods; whereby morbid exhalations have been multiplied, and their

passage rendered more free, through every part of country.

This is a short account of the remedies of the Indians. If they are

simple, they are like their eloquence, full of strength; if they are few

in number, they are accommodated, as their languages are to their ideas,

to the whole of their diseases.

We said, formerly, that the Indians were subject to ACCIDENTS, such as

wounds, fractures, and the like. In these cases, nature performs the

office of a surgeon. We may judge of her qualifications for this office,

by observing the marks of wounds and fractures, which are sometimes

discovered on wild animals. But further, what is the practice of our

modern surgeons in these cases? Is it not to lay aside plasters and

ointments, and trust the whole to nature? Those ulcers which require the

assistance of mercury, bark, and a particular regimen are unknown to the

Indians.

The HEMORRHAGES which sometimes follow their wounds, are restrained

by plunging themselves into cold water, and thereby producing a

constriction upon the bleeding vessels.

Their practice of attempting to recover DROWNED PEOPLE, is irrational

and unsuccessful. It consists in suspending the patient by the heels, in

order that the water may flow from his mouth. This practice is founded

on a belief that the patient dies from swallowing an excessive quantity

of water. But modern observations teach us that drowned people die from

another cause. This discovery has suggested a method of cure, directly

opposite to that in use among the Indians; and has shown us that the

practice of suspending by the heels is hurtful.

I do not find that the Indians ever suffer in their limbs from the

action of COLD upon them. Their mokasons[8], by allowing their feet to

move freely, and thereby promoting the circulation of the blood, defend

their lower extremities in the day-time, and their practice of sleeping

with their feet near a fire, defends them from the morbid effects of

cold at night. In those cases where the motion of their feet in their

mokasons is not sufficient to keep them warm, they break the ice, and

restore their warmth by exposing them for a short time to the action of

cold water[9].

[8] Indian shoes.

[9] It was remarked in Canada, in the winter of the year 1759, during

the war before last, that none of those soldiers who wore mokasons

were frost-bitten, while few of those escaped that were much

exposed to the cold who wore shoes.

We have heard much of their specific antidotes to the VENEREAL DISEASE.

In the accounts of these anti-venereal medicines, some abatement should

be made for that love of the marvellous, and of novelty, which are

apt to creep into the writings of travellers and physicians. How many

medicines which were once thought infallible in this disease, are now

rejected from the materia medica! I have found upon inquiry that the

Indians always assist their medicines in this disease, by a regimen

which promotes perspiration. Should we allow that mercury acts as a

specific in destroying this disease, it does not follow that it is proof

against the efficacy of medicines which act more mechanically upon the

body[10].

[10] I cannot help suspecting the anti-venereal qualities of the

lobelia, ceanothus and ranunculus, spoken of by Mr. Kalm, in the

Memoirs of the Swedish Academy. Mr. Hand informed me, that the

Indians rely chiefly upon a plentiful use of the decoctions of

the pine-trees for the cure of the venereal disease. He added,

moreover, that he had often known this disease prove fatal to

them.

There cannot be a stronger mark of the imperfect state of knowledge in

medicine among the Indians, than their method of treating the SMALL-POX.

We are told that they plunge themselves in cold water in the beginning

of the disease, and that it often proves fatal to them.

Travellers speak in high terms of the Indian ANTIDOTES TO POISONS. We

must remember that many things have been thought poisonous, which later

experience hath proved to possess no unwholesome quality. Moreover,

the uncertainty and variety in the operation of poisons, renders it

extremely difficult to fix the certainty of the antidotes to them. How

many specifics have derived their credit for preventing the hydrophobia,

from persons being wounded by animals, who were not in a situation to

produce that disease! If we may judge of all the Indian antidotes to

poisons, by those which have fallen into our hands, we have little

reason to ascribe much to them in any cases whatever.

I have heard of their performing several remarkable cures upon STIFF

JOINTS, by an infusion of certain herbs in water. The mixture of

several herbs together in this infusion calls in question the specific

efficacy of each of them. I cannot help attributing the whole success

of this remedy to the great heat of the water in which the herbs were

boiled, and to its being applied for a long time to the part affected.

We find the same medicine to vary frequently in its success, according

to its strength, or to the continuance of its application. De Haen

attributes the good effects of electricity, entirely to its being used

for several months.

I have met with one case upon record of their aiding nature in

PARTURITION. Captain Carver gives us an account of an Indian woman in a

difficult labour, being suddenly delivered in consequence of a general

convulsion induced upon her system, by stopping, for a short time, her

mouth and nose, so as to obstruct her breathing.

We are sometimes amused with accounts of Indian remedies for the DROPSY,

EPILEPSY, COLIC, GRAVEL, and GOUT. If, with all the advantages which

modern physicians derive from their knowledge in anatomy, chemistry,

botany, and philosophy; if, with the benefit of discoveries communicated

from abroad, as well as handed down from our ancestors, by more certain

methods than tradition, we are still ignorant of certain remedies for

these diseases; what can we expect from the Indians; who are not only

deprived of these advantages, but want our chief motive, the sense of

the pain and danger of those diseases, to prompt them to seek for such

remedies to relieve them? There cannot be a stronger proof of their

ignorance of proper remedies for new or difficult diseases, than their

having recourse to enchantment. But to be more particular; I have taken

pains to inquire into the success of some of these Indian specifics,

and have never heard of one well attested case of their efficacy. I

believe they derive all their credit from our being ignorant of their

composition. The influence of secrecy is well known in establishing

the credit of a medicine. The sal seignette was supposed to be an

infallible medicine for the intermitting fever, while the manufactory of

it was confined to an apothecary at Rochelle; but it lost its virtues

as soon as it was found to be composed of the acid of tartar and the

fossil alkali. Dr. Ward's famous pill and drop ceased to do wonders in

scrophulous cases, as soon as he bequeathed to the world his receipts

for making them.

I foresee an objection to what has been said concerning the remedies of

the Indians, drawn from that knowledge which experience gives to a mind

intent upon one subject. We have heard much of the perfection of their

senses of seeing and hearing. An Indian, we are told, will discover

not only a particular tribe of Indians by their footsteps, but the

distance of time in which they were made. In those branches of knowledge

which relate to hunting and war, the Indians have acquired a degree of

perfection that has not been equalled by civilized nations. But we must

remember, that medicine among them does not possess the like advantages

with the arts of war and hunting, of being the _chief_ object of their

attention. The physician and the warrior are united in one character;

to render him as able in the former as he is in the latter profession,

would require an entire abstraction from every other employment, and

a familiarity with external objects, which are incompatible with the

wandering life of savages.

Thus have we finished our inquiry into the diseases and remedies of the

Indians in North-America. We come now to inquire into the diseases and

remedies of civilized nations.

Nations differ in their degrees of civilization. We shall select one

for the subject of our inquiries which is most familiar to us; I mean

the British nation. Here we behold subordination and classes of mankind

established by government, commerce, manufactures, and certain customs

common to most of the civilized nations of Europe. We shall trace the

origin of their diseases through their customs, in the same manner as we

did those of the Indians.

I. It will be sufficient to name the degrees of heat, the improper

aliment, the tight dresses, and the premature studies children are

exposed to, in order to show the ample scope for diseases, which is

added to the original defect of stamina they derive from their ancestors.

II. Civilization rises in its demands upon the health of women. Their

fashions; their dress and diet; their eager pursuits and ardent

enjoyment of pleasure; their indolence and undue evacuations in

pregnancy; their cordials, hot regimen, and neglect, or use of art, in

child-birth, are all so many inlets to disease.

Humanity would fain be silent, while philosophy calls upon us to mention

the effects of interested marriages, and of disappointments in love,

increased by that concealment which the tyranny of custom has imposed

upon the sex[11]. Each of these exaggerates the natural, and increases

the number of artificial diseases among women.

[11] "Married women are more healthy and long-lived than single women.

The registers, examined by Mr. Muret, confirm this observation;

and show particularly, that of equal numbers of single and

married women between fifteen and twenty-five years of age, more

of the former died than of the latter, in the proportion of two

to one: the consequence, therefore, of following nature must be

favourable to health among the female sex." Supplement to Price's

Observations on Reversionary Payments. p. 357.

III. The diseases introduced by civilization extend themselves through

every class and profession among men. How fatal are the effects of

idleness and intemperance among the rich, and of hard labour and penury

among the poor! What pallid looks are contracted by the votaries of

science from hanging over the "sickly taper!" How many diseases are

entailed upon manufacturers, by the materials in which they work, and

the posture of their bodies! What monkish diseases do we observe from

monkish continence and monkish vices! We pass over the increase of

accidents from building, sailing, riding, and the like. War, as if too

slow in destroying the human species, calls in a train of diseases

peculiar to civilized nations. What havoc have the corruption and

monopoly of provisions, a damp soil, and an unwholesome sky, made, in

a few days, in an army! The achievements of British valour, at the

Havannah, in the last war, were obtained at the expence of 9,000 men,

7,000 of whom perished with the West-India fever[12]. Even our modern

discoveries in geography, by extending the empire of commerce, have

likewise extended the empire of diseases. What desolation have the East

and West-Indies made of British subjects! It has been found, upon a nice

calculation, than only ten of a hundred Europeans, live above seven

years after they arrive in the island of Jamaica.

[12] The modern writers upon the diseases of armies, wonder that the

Greek and Roman physicians have left us nothing upon that

subject. But may not _most_ of the diseases of armies be produced

by the different manner in which wars are carried on by the

modern nations? The discoveries in geography, by extending the

field of war, expose soldiers to many diseases from long voyages,

and a _sudden_ change of climate, which were unknown to the

armies of former ages. Moreover, the form of the weapons, and

the variety in the military exercises of the Grecian and Roman

armies, gave a vigour to the constitution, which can never be

acquired by the use of muskets and artillery.

IV. It would take up too much of our time to point out all the customs,

both _physical_ and _moral_, which influence diseases among both sexes.

The former have engendered the seeds of diseases in the human body

itself: hence the origin of catarrhs, jail and miliary fevers, with

a long train of other diseases, which compose so great a part of our

books of medicine. The latter likewise have a large share in producing

diseases. I am not one of those modern philosophers, who derive the

vices of mankind from the influence of civilization; but I am safe in

asserting, that their number and malignity increase with the refinements

of polished life. To prove this, we need only survey a scene too

familiar to affect us: it is a bedlam; which injustice, inhumanity,

avarice, pride, vanity, and ambition, have filled with inhabitants.

Thus have I briefly pointed out the customs which influence the diseases

of civilized nations. It remains now that we take notice of their

diseases. Without naming the many new fevers, fluxes, hemorrhages,

swellings from water, wind, flesh, fat, pus, and blood; foulnesses on

the skin, from cancers, leprosy, yawes, poxes, and itch; and, lastly,

the gout, the hysteria, and the hypochondriasis, in all their variety

of known and unknown shapes; I shall sum up all that is necessary upon

this subject, by adding, that the number of diseases which belong to

civilized nations, according to Doctor Cullen's nosology, amounts to

1387; the single class of nervous diseases form 612 of this number.

Before we proceed to speak of the remedies of civilized nations, we

shall examine into the abilities of NATURE in curing their diseases. We

found her active and successful in curing the diseases of the Indians.

Are her strength, wisdom, or benignity, equal to the increase of those

dangers which threaten her dissolution among civilized nations? In order

to answer this question, it will be necessary to explain the meaning of

the term nature.

By nature, in the present case, I understand nothing but _physical

necessity_. This at once excludes every thing like intelligence from

her operations: these are all performed in obedience to the same laws

which govern vegetation in plants, and the intestine motions of fossils.

They are as truly mechanical as the laws of gravitation, electricity,

or magnetism. A ship when laid on her broadside by a wave, or a sudden

blast of wind, rises by the simple laws of her mechanism; but suppose

this ship to be attacked by fire, or a water-spout, we are not to call

in question the skill of the ship-builder, if she be consumed by the

one, or sunk by the other. In like manner, the Author of nature hath

furnished the body with powers to preserve itself from its natural

enemies; but when it is attacked by those civil foes which are bred by

the peculiar customs of civilization, it resembles a company of Indians,

armed with bows and arrows, against the complicated and deadly machinery

of fire-arms. To place this subject in a proper light, I shall deliver

a history of the operations of nature in a few of the diseases of

civilized nations.

I. There are cases in which nature is still successful in curing

diseases.

In fevers she still deprives us of our appetite for animal food, and

imparts to us a desire for cool air and cold water.

In hemorrhages she produces a faintness, which occasions a coagulum in

the open vessels; so that the further passage of blood through them is

obstructed.

In wounds of the flesh and bones she discharges foreign matter by

exciting an inflammation, and supplies the waste of both with new flesh

and bone.

II. There are cases where the efforts of nature are too feeble to do

service, as in malignant and chronic fevers.

III. There are cases where the efforts of nature are over proportioned

to the strength of the disease, as in the cholera morbus and dysentery.

IV. There are cases where nature is idle, as in the atonic stages of the

gout, the cancer, the epilepsy, the mania, the venereal disease, the

apoplexy, and the tetanus[13].

[13] Hoffman de hypothesium medicarum damno, sect. xv.

V. There are cases in which nature does mischief. She wastes herself

with an unnecessary fever, in a dropsy and consumption. She throws a

plethora upon the brain and lungs in the apoplexy and peripneumonia

notha. She ends a pleurisy and peripneumony in a vomica, or empyema. She

creates an unnatural appetite for food in the hypochondriac disease.

And, lastly, she drives the melancholy patient to solitude, where, by

brooding over the subject of his insanity, he increases his disease.

We are accustomed to hear of the salutary kindness of nature in alarming

us with pain, to prompt us to seek for a remedy. But,

VI. There are cases in which she refuses to send this harbinger of the

evils which threaten her, as in the aneurism, schirrhous, and stone in

the bladder.

VII. There are cases where the pain is not proportioned to the danger,

as in the tetanus, consumption, and dropsy of the head. And,

VIII. There are cases where the pain is over-proportioned to the danger,

as in the paronychia and tooth-ach.

This is a short account of the operations of nature, in the diseases

of civilized nations. A lunatic might as well plead against the

sequestration of his estate, because he once enjoyed the full exercise

of his reason, or because he still had lucid intervals, as nature be

exempted from the charges we have brought against her.

But this subject will receive strength from considering the REMEDIES of

civilized nations. All the products of the vegetable, fossil, and animal

kingdoms, tortured by heat and mixture into an almost infinite variety

of forms; bleeding, cupping, artificial drains by setons, issues, and

blisters; exercise, active and passive; voyages and journies; baths,

warm and cold; waters, saline, aërial, and mineral; food by weight and

measure; the royal touch; enchantment; miracles; in a word, the combined

discoveries of natural history and philosophy, united into a system of

materia medica, all show, that although physicians are in speculation

the servants, yet in practice they are the masters of nature. The whole

of their remedies seem contrived on purpose to arouse, assist, restrain,

and controul her operations.

There are some truths like certain liquors, which require strong heads

to bear them. I feel myself protected from the prejudices of vulgar

minds, when I reflect that I am delivering these sentiments in a society

of philosophers.

Let us now take a COMPARATIVE VIEW of the diseases and remedies of the

Indians with those of civilized nations. We shall begin with their

diseases.

In our account of the diseases of the Indians, we beheld death executing

his commission, it is true; but then his dart was hid in a mantle, under

which he concealed his shape. But among civilized nations we behold

him multiplying his weapons in proportion to the number of organs and

functions in the body; and pointing each of them in such a manner, as to

render his messengers more terrible than himself.

We said formerly that fevers constituted the chief diseases of the

Indians. According to Doctor Sydenham's computation, above 66,000 out of

100,000 died of fevers in London, about 100 years ago; but fevers now

constitute but a little more than one-tenth part of the diseases of that

city. Out of 21,780 persons who died in London between December, 1770,

and December, 1771, only 2273 died of simple fevers. I have more than

once heard Doctor Huck complain, that he could find no marks of epidemic

fevers in London, as described by Dr. Sydenham. London has undergone

a revolution in its manners and customs since Doctor Sydenham's time.

New diseases, the offspring of luxury, have supplanted fevers; and the

few that are left are so complicated with other diseases, that their

connection can no longer be discovered with an epidemic constitution of

the year. The pleurisy and peripneumony, those inflammatory fevers of

strong constitutions, are now lost in catarrhs, or colds, which, instead

of challenging the powers of nature or art to a fair combat, insensibly

undermine the constitution, and bring on an incurable consumption. Out

of 22,434 who died in London between December, 1769, and the same month

in 1770, 4594 perished with that British disease. Our countryman, Doctor

Maclurg, has ventured to foretel that the gout will be lost in a few

years, in a train of hypochondriac, hysteric, and bilious diseases.

In like manner, may we not look for a season when fevers, the natural

diseases of the human body, will be lost in an inundation of artificial

diseases, brought on by the modish practices of civilization?

It may not be improper to compare the PROGNOSIS of the Indians, in

diseases, with that of civilized nations, before we take a comparative

view of their remedies.

The Indians are said to be successful in predicting the events of

diseases. While diseases are simple, the marks which distinguish

them, or characterize their several stages, are generally uniform and

obvious to the most indifferent observer. These marks afford so much

certainty, that the Indians sometimes kill their physicians for a false

prognosis, charging the death of the patient to their carelessness, or

ignorance. They estimate the danger of their patients by the degrees

of appetite; while an Indian is able to eat, he is looked upon as free

from danger. But when we consider the number and variety in the signs

of diseases, among civilized nations, together with the shortness of

life, the fallacy of memory, and the uncertainty of observation, where

shall we find a physician willing to risk his reputation, much less his

life, upon the prediction of the event of our acute diseases? We can

derive no advantage from the simple sign, by which the Indians estimate

the danger of their patients; for we daily see a want of appetite for

food in diseases which are attended with no danger; and we sometimes

observe an unusual degree of this appetite to precede the agonies of

death. I honour the name of HIPPOCRATES: but forgive me, ye votaries of

antiquity, if I attempt to pluck a few grey hairs from his venerable

head. I was once an idolater at his altar, nor did I turn apostate from

his worship, till I was taught, that not a tenth part of his prognostics

corresponded with modern experience, or observation. The pulse[14],

urine, and sweats, from which the principal signs of life and death

have been taken, are so variable, in most of the acute diseases of

civilized nations, that the wisest physicians have in some measure

excluded the prognosis from being a part of their profession.

[14] Doctor Cullen used to inform his pupils, that after forty years'

experience, he could find no relation between his own

observations on the pulse, and those made by Doctor Solano. The

climate and customs of the people in Spain being so different

from the climate and customs of the present inhabitants of

Britain, may account for the diversity of their observations.

Doctor Heberden's remarks upon the pulse, in the second volume of

the Medical Transactions, are calculated to show how little the

issue of diseases can be learned from it.

I am here insensibly led to make an apology for the instability of the

theories and practice of physic. The theory of physic is founded upon

the laws of the animal economy. These (unlike the laws of the mind, or

the common laws of matter) do not appear at once, but are gradually

brought to light by the phænomena of diseases. The success of nature in

curing the simple diseases of Saxony, laid the foundation for the ANIMA

MEDICA of Doctor STAHL. The endemics of Holland[15] led Doctor BOERHAAVE

to seek for the causes of all diseases in the FLUIDS. And the universal

prevalence of diseases of the NERVES, in Great-Britain, led Doctor

CULLEN to discover their peculiar laws, and to found a system upon them;

a system, which will probably last till some new diseases are let loose

upon the human species, which shall unfold other laws of the animal

economy.

[15] "The scurvy is very frequent in Holland; and draws its origin

partly from their strong food, sea-fish, and smoked flesh, and

partly from their dense and moist air, together with their bad

water." Hoffman on Endemical Distempers.

"We are now in North-Holland; and I have never seen, among so

few people, so many infected with the leprosy as here. They say

the reason is, because they eat so much fish." Howell's Familiar

Letters.

It is in consequence of this fluctuation in the principles and practice

of physic, being so necessarily connected with the changes in the

customs of civilized nations, that old and young physicians so often

disagree in their opinions and practices. And it is by attending to

the constant changes in these customs of civilized nations, that those

physicians have generally become the most eminent, who have soonest

emancipated themselves from the tyranny of the schools of physic; and

have occasionally accommodated their principles and practice to the

changes in diseases[16]. This variety in diseases, which is produced

by the changes in the customs of civilized nations, will enable us to

account for many of the contradictions which are to be found in authors

of equal candour and abilities, who have written upon the materia medica.

[16] We may learn from these observations, the great impropriety of

those Egyptian laws which oblige physicians to adopt, in all

cases, the prescriptions which had been collected, and approved

of, by the physicians of former ages. Every change in the customs

of civilized nations, produces a change in their diseases, which

calls for a change in their remedies. What havoc would plentiful

bleeding, purging, and small beer, formerly used with so much

success by Dr. Sydenham in the cure of fevers, now make upon the

enfeebled citizens of London! The fevers of the same, and of more

southern latitudes, still admit of such antiphlogistic remedies.

In the room of these, bark, wine, and other cordial medicines,

are prescribed in London in almost every kind of fever.

In forming a comparative view of the REMEDIES of the Indians, with those

of civilized nations, we shall remark, that the want of success in a

medicine is occasioned by one of the following causes:

First, our ignorance of the disease. Secondly, an ignorance of a

suitable remedy. Thirdly, a want of efficacy in the remedy.

Considering the violence of the diseases of the Indians, it is probable

their want of success is always occasioned by a want of efficacy in

their medicines. But the case is very different among the civilized

nations. Dissections daily convince us of our ignorance of the seats

of diseases, and cause us to blush at our prescriptions. How often are

we disappointed in our expectation from the most certain and powerful

of our remedies, by the negligence or obstinacy of our patients!

What mischief have we done under the belief of false facts (if I

may be allowed the expression) and false theories! We have assisted

in multiplying diseases. We have done more--we have increased their

mortality.

I shall not pause to beg pardon of the faculty, for acknowledging, in

this public manner, the weaknesses of our profession. I am pursuing

Truth, and while I can keep my eye fixed upon my guide, I am indifferent

whether I am led, provided she is my leader.

But further, the Indian submits to his disease, without one fearful

emotion from his doubtfulness of its event; and at last meets his fate

without an an anxious wish for futurity; except it is of being admitted

to an "equal sky," where

"His faithful dog shall bear him company."

But, among civilized nations, the influence of a false religion in good,

and of a true religion in bad men, has converted even the fear of death

into a disease. It is this original distemper of the imagination which

renders the plague most fatal, upon his first appearance in a country.

Under all these disadvantages in the state of medicine, among civilized

nations, do more in proportion die of the diseases peculiar to them,

than of fevers, casualties, and old age, among the Indians? If we take

our account from the city of London, we shall find this to be the case.

Near a twentieth part of its inhabitants perish one year with another.

Nor does the natural increase of inhabitants supply this yearly waste.

If we judge from the bills of mortality, the city of London contains

fewer inhabitants, by several thousands, than it did forty years ago. It

appears from this fact, and many others of a like nature, which might be

adduced, that although the difficulty of supporting children, together

with some peculiar customs of the Indians, which we mentioned, limit

their number, yet they multiply faster, and die in a smaller proportion

than civilized nations, under the circumstances we have described.

The Indians, we are told, were numerous in this country, before the

Europeans settled among them. Travellers agree likewise in describing

numbers of both sexes who exhibited all the marks of extreme old age. It

is remarkable that age seldom impairs the faculties of their minds.

The mortality peculiar to those Indian tribes who have mingled with the

white people, must be ascribed to the extensive mischief of spiritous

liquors. When these have not acted, they have suffered from having

accommodated themselves too suddenly to the European diet, dress, and

manners. It does not become us to pry too much into futurity; but if we

may judge from the fate of the original natives of Hispaniola, Jamaica,

and the provinces on the continent, we may venture to foretel, that, in

proportion as the white people multiply, the Indians will diminish; so

that in a few centuries they will probably be entirely extirpated[17].

[17] Even the influence of CHRISTIAN principles has not been able to

put a stop to the mortality introduced among the Indians, by

their intercourse with the Europeans. Dr. Cotton Mather, in a

letter to sir William Ashurst, printed in Boston, in the year

1705, says, "that about five years before there were about thirty

Indian congregations in the southern parts of the province

of Massachusetts-Bay." The same author, in his history of

New-England, says, "That in the islands of Nantucket and Martha's

Vineyard, there were 3000 _adult_ Indians, 1600 of whom professed

the christian religion." At present there is but _one_ Indian

congregation in the whole Massachusetts province.

It may serve to extend our knowledge of diseases, to remark, that

epidemics were often observed to prevail among the Indians in

Nantucket, without affecting the white people.

It may be said, that health among the Indians, like insensibility to

cold and hunger, is proportioned to their need of it; and that the less

degrees, or entire want of health, are no interruption to the ordinary

business of civilized life.

To obviate this supposition, we shall first attend to the effects of

a single disease in those people who are the principal wheels in the

machine of civil society. Justice has stopt its current, victories have

been lost, wars have been prolonged, and embassies delayed, by the

principal actors in these departments of government being suddenly laid

up by a fit of the gout. How many offences are daily committed against

the rules of good breeding, by the tedious histories of our diseases,

which compose so great a part of modern conversation! What sums of money

have been lavished in foreign countries in pursuit of health[18]!

Families have been ruined by the unavoidable expences of medicines and

watering-places. In a word, the swarms of beggars which infest so many

of the European countries, urge their petitions for charity chiefly by

arguments derived from real or counterfeit diseases, which render them

incapable of supporting themselves[19].

[18] It is said, there are seldom less than 20,000 British subjects in

France and Italy; one half of whom reside or travel in those

countries upon the account of their health.

[19] Templeman computes, that Scotland contains 1,500,000 inhabitants;

100,000 of whom, according to Mr. Fletcher, are supported at the

public expence. The proportion of poor people is much greater in

England, Ireland, France, and Italy.

But may not civilization, while it abates the violence of natural

diseases, increase the lenity of those that are artificial, in the same

manner that it lessens the strength of natural vices by multiplying

them? To answer this question, it will only be necessary to ask another:

Who should exchange the heat, thirst, and uneasiness of a fever, for one

fit of the colic or stone?

The history of the number, combination, and fashions of the remedies

we have given, may serve to humble the pride of philosophy; and to

convince us, that with all the advantages of the whole circle of

sciences, we are still ignorant of antidotes to many of the diseases of

civilized nations. We sometimes sooth our ignorance, by reproaching our

idleness in not investigating the remedies peculiar to this country.

We are taught to believe that every herb that grows in our woods is

possessed of some medicinal virtue, and that Heaven would be wanting in

benignity, if our country did not produce remedies for all the different

diseases of its inhabitants. It would be arrogating too much to suppose

that man was the only creature in our world for whom vegetables grow.

The beasts, birds, and insects, derive their sustenance either directly

or indirectly from them; while many of them were probably intended,

from their variety in figure, foliage, and colour, only to serve as

ornaments for our globe. It would seem strange that the Author of

nature should furnish every spot of ground with medicines adapted to

the diseases of its inhabitants, and at the same time deny it the more

necessary articles of food and clothing. I know not whether Heaven has

provided every country with antidotes even to the _natural_ diseases

of its inhabitants. The intermitting fever is common in almost every

corner of the globe; but a sovereign remedy for it has been discovered

only in South-America. The combination of bitter and astringent

substances, which serve as a succedaneum to the Peruvian bark, is as

much a preparation of art, as calomel or tartar emetic. Societies stand

in need of each other as much as individuals; and the goodness of the

Deity remains unimpeached when we suppose, that he intended medicines

to serve (with other articles) to promote that knowledge, humanity, and

politeness among the inhabitants of the earth, which have been so justly

attributed to commerce.

We have no discoveries in the materia medica to hope for from the

Indians in North-America. It would be a reproach to our schools of

physic, if modern physicians were not more successful than the Indians,

even in the treatment of their own diseases.

Do the blessings of civilization compensate for the sacrifice we make

of natural health, as well as of natural liberty? This question must be

answered under some limitations. When natural liberty is given up for

laws which enslave instead of protecting us, we are immense losers by

the exchange. Thus, if we arm the whole elements against our health, and

render every pore in the body an avenue for a disease, we pay too high

a price for the blessings of civilization.

In governments which have departed entirely from their simplicity,

partial evils are to be cured by nothing but an entire renovation of

their constitution. Let the world bear with the professions of law,

physic, and divinity; and let the lawyer, physician, and divine yet

learn to bear with each other. They are all necessary, in the present

state of society. In like manner, let the woman of fashion forget the

delicacy of her sex, and submit to be delivered by a man-midwife[20].

Let her snatch her offspring from her breast, and send it to repair the

weakness of its stamina, with the milk of a ruddy cottager[21]. Let art

supply the place of nature in the preparation and digestion of all our

aliment. Let our fine ladies keep up their colour with carmine, and

their spirits with ratifia; and let our fine gentlemen defend themselves

from the excesses of heat and cold, with lavender and hartshorn. These

customs have become necessary in the corrupt stages of society. We must

imitate, in these cases, the practice of those physicians who consult

the appetite only, in diseases which do not admit of a remedy.

[20] In the enervated age of Athens, a law was passed which confined

the practice of midwifery only to the men. It was, however,

repealed, upon a woman's dying in childbirth, rather than

be delivered by a man-midwife. It appears from the bills of

mortality in London and Dublin, that about one in seventy of

those women die in childbirth, who are in the hands of midwives;

but from the accounts of the lying-in hospitals in those cities,

which are under the care of man-midwives, only one in a hundred

and forty perishes in childbirth.

[21] There has been much common-place declamation against the custom

among the great, of not suckling their children. Nurses were

common in Rome, in the declension of the empire: hence we find

Cornelia commended as a rare example of maternal virtue, as much

for suckling her sons, as for teaching them eloquence. That

nurses were common in Egypt, is probable from the contract which

Pharaoh's daughter made with the unknown mother of Moses, to

allow her wages for suckling her own child. The same degrees of

civilization require the same customs. A woman whose times for

eating and sleeping are constantly interrupted by the calls of

enervating pleasures, must always afford milk of an unwholesome

nature. It may truly be said of a child doomed to live on this

aliment, that, as soon as it receives its

------"breath,

It sucks in "the lurking principles of death."

The state of a country in point of population, temperance, and industry,

is so connected with its diseases, that a tolerable idea may be formed

of it, by looking over its bills of mortality. HOSPITALS, with all

their boasted advantages, exhibit at the same time monuments of the

charity and depravity of a people[22]. The opulence of physicians, and

the divisions of their offices, into those of surgery, pharmacy, and

midwifery, are likewise proofs of the declining state of a country. In

the infancy of the Roman empire, the priest performed the office of a

physician; so simple were the principles and practice of physic. It

was only in the declension of the empire that physicians vied with the

emperors of Rome in magnificence and splendour[23].

[22] "Aurengezebe, emperor of Persia, being asked, Why he did not build

hospitals? said, _I will make my empire so rich, that there shall

be no need of hospitals_. He ought to have said, I will begin by

rendering my subjects rich, and then I will build hospitals.

"At Rome, the hospitals place every one at his ease, except those

who labour, those who are industrious, those who have lands, and

those who are engaged in trade.

"I have observed, that wealthy nations have need of hospitals,

because fortune subjects them to a thousand accidents; but it

is plain, that transient assistances are better than perpetual

foundations. The evil is momentary; it is necessary, therefore,

that the succour should be of the same nature, and that it be

applied to particular accidents." Spirit of Laws, b. xxiii. ch.

29.

It was reserved for the present generation to substitute in the

room of public hospitals private DISPENSARIES for the relief of

the sick. Philosophy and christianity alike concur in deriving

praise and benefit from these excellent institutions. They

exhibit something like an application of the mechanical powers

to the purposes of benevolence; for in what other charitable

institutions do we perceive so great a _quantity_ of distress

relieved by so small an expence?

[23] The first regular practitioners of physic in Rome, were women and

slaves. The profession was confined to them above six hundred

years. The Romans, during this period, lived chiefly upon

vegetables, particularly upon PULSE; and hence they were called,

by their neighbours, PULTIFAGI. They were likewise early inured

to the healthy employments of war and husbandry. Their diseases,

of course, were too few and simple to render the cure of them

an object of liberal profession. When their diseases became

more numerous and complicated, their investigation and cure

required the aids of philosophy. The profession from this time

became liberal; and maintained a rank with the other professions

which are founded upon the imperfection and depravity of human

institutions. Physicians are as necessary in the advanced stages

of society as surgeons, although their office is less ancient

and certain. There are many artificial diseases, in which they

give certain relief; and even where their art fails, their

prescriptions are still necessary, in order to smooth the avenues

of death.

I am sorry to add, in this place, that the number of patients in the

HOSPITAL, and incurables in the ALMSHOUSE of this city, show that we are

treading in the enervated steps of our fellow subjects in Britain. Our

bills of mortality likewise show the encroachments of British diseases

upon us. The NERVOUS FEVER has become so familiar to us, that we look

upon it as a natural disease. Dr. Sydenham, so faithful in his history

of fevers, takes no notice of it. Dr. Cadwallader informed me, that it

made its first appearance in this city about five and twenty years ago.

It will be impossible to name the CONSUMPTION without recalling to our

minds the memory of some friend or relation, who has perished within

these few years by that disease. Its rapid progress among us has been

unjustly attributed to the growing resemblance of our climate to that of

Great-Britain. The HYSTERIC and HYPOCHONDRIAC DISEASES, once peculiar

to the chambers of the great, are now to be found in our kitchens and

workshops. All these diseases have been produced by our having deserted

the simple diet and manners of our ancestors.

The blessings of literature, commerce, and religion were not

_originally_ purchased at the expence of health. The complete enjoyment

of health is as compatible with civilization, as the enjoyment of

civil liberty. We read of countries, rich in every thing that can

form national happiness and national grandeur, the diseases of which

are nearly as few and simple as those of the Indians. We hear of no

diseases among the Jews, while they were under their democratical

form of government, except such as were inflicted by a supernatural

power[24]. We should be tempted to doubt the accounts given of the

populousness of that people, did we not see the practice of their simple

customs producing nearly the same populousness in Egypt, Rome, and other

countries of antiquity. The empire of China, it is said, contains more

inhabitants than the whole of Europe. The political institutions of that

country have exempted its inhabitants from a large share of the diseases

of other civilized nations. The inhabitants of Switzerland, Denmark,

Norway[25], and Sweden, enjoy the chief advantages of civilization

without having surrendered for them the blessings of natural health. But

it is unnecessary to appeal to ancient or remote nations to prove, that

health is not incompatible with civilization. The inhabitants of many

parts of New-England, particularly of the province of Connecticut, are

but little affected by artificial diseases. Some of you may remember

the time, and our fathers have told those of us who do not, when the

diseases of PENNSYLVANIA were as few and as simple as those of the

Indians. The food of the inhabitants was then simple; their only drink

was water; their appetites were restrained by labour; religion excluded

the influence of sickening passions; private hospitality supplied the

want of a public hospital; nature was their only nurse, and temperance

their principal physician. But I must not dwell upon this retrospect

of primæval manners; and I am too strongly impressed with a hope of a

revival of such happy days, to pronounce them the golden age of our

province.

[24] The principal employments of the Jews, like those of the Romans in

their simple ages, consisted in war and husbandry. Their diet was

plain, consisting chiefly of vegetables. Their only remedies were

plasters and ointments; which were calculated for those diseases

which are produced by accidents. In proportion as they receded

from their simple customs, we find artificial diseases prevail

among them. The leprosy made its appearance in their journey

through the wilderness. King Asa's pains in his feet, were

probably brought on by a fit of the gout. Saul and Nebuchadnezzar

were afflicted with a melancholy. In the time of our Saviour,

we find an account of all those diseases in Judea, which mark

the declension of a people; such as, the palsy, epilepsy, mania,

blindness, hæmorrhagia uterina, &c. It is unnecessary to suppose,

that they were let loose at this juncture, on purpose to give

our Saviour an opportunity of making them the chief subject of

his miracles. They had been produced from natural causes, by

the gradual depravity of their manners. It is remarkable, that

our Saviour chose those artificial diseases for the subject of

his miracles, in preference to natural diseases. The efforts

of nature, and the operation of medicines, are too slow and

uncertain in these cases to detract in the least from the

validity of the miracle. He cured Peter's mother-in-law, it is

true, of a fever; but to show that the cure was miraculous, the

sacred historian adds (contrary to what is common after a fever),

"that she arose _immediately_, and ministered unto them."

[25] In the city of Bergen, which consists of 30,000 inhabitants, there

is but one physician; who is supported at the expense of the

public. Pontoppidan's Nat. Hist. of Norway.

Our esteem for the customs of our savage neighbours will be lessened,

when we add, that civilization does not preclude the honours of old age.

The proportion of old people is much greater among civilized, than among

savage nations. It would be easy to decide this assertion in our favour,

by appealing to facts in the natural histories of Britain, Norway,

Sweden, North-America[26], and several of the West-India islands.

[26] It has been urged against the state of longevity in America, that

the Europeans, who settle among us, generally arrive to a

greater age than the Americans. This is not occasioned so much

by a peculiar firmness in their stamina, as by an increase of

vigour which the constitution acquires by a change of climate. A

Frenchman (cæteris paribus) outlives an Englishman in England. A

Hollander prolongs his life by removing to the Cape of Good Hope.

A Portuguese gains fifteen or twenty years by removing to Brazil.

And there are good reasons to believe, that a North-American

would derive the same advantages, in point of health and

longevity, by removing to Europe, which a European derives from

coming to this country.

From a calculation made by an ingenious foreigner, it appears,

that a greater proportion of old people are to be found in

Connecticut, than in any colony in North-America. This colony

contains 180,000 inhabitants. They have no public hospitals or

poor-houses; nor is a beggar to be seen among them. There cannot

be more striking proofs than these facts of the simplicity of

their manners.

The laws of decency and nature are not necessarily abolished by the

customs of civilized nations. In many of these, we read of women among

whom nature alone still performs the office of a midwife[27], and who

feel the obligations of suckling their children to be equally binding

with the common obligations of morality.

[27] Parturition, in the simple ages of all countries, is performed by

nature. The Israelitish women were delivered even without the

help of the Egyptian midwives. We read of but two women who died

in child-birth in the whole history of the Jews. Dr. Bancroft

says, that child-bearing is attended with so little pain in

Guiana, that the women seem to be exempted from the curse

inflicted upon Eve. These easy births are not confined to warm

climates. They are equally safe and easy in Norway and Iceland,

according to Pontoppidan and Anderson's histories of those

countries.

Civilization does not render us less fit for the necessary hardships of

war. We read of armies of civilized nations, who have endured degrees of

cold, hunger, and fatigue, which have not been exceeded by the savages

of any country[28].

[28] Civilized nations have, in the end, always conquered savages as

much by their ability to bear hardships, as by their superior

military skill. Soldiers are not to be chosen indiscriminately.

The greatest generals have looked upon sound constitutions to

be as essential to soldiers, as bravery or military discipline.

Count Saxe refused soldiers born and bred in large cities; and

sought for such only as were bred in mountainous countries.

The King of Prussia calls young soldiers only to the dangers

and honours of the field, in his elegant poem, Sur l'Art de la

Guerre, chant 1. Old soldiers generally lose the advantages of

their veteranism, by their habits of idleness and debauchery. An

able general, and experienced officers, will always supply the

defects of age in young soldiers.

Civilization does not always multiply the avenues of death. It appears

from the bills of mortality, of many countries, that fewer in proportion

die among civilized, than among savage nations.

Even the charms of beauty are heightened by civilization. We read of

stateliness, proportion, line teeth[29] and complexions, in both sexes,

forming the principal outlines of national characters.

[29] Bad teeth are observed chiefly in middle latitudes, which are

subject to alternate heats and colds. The inhabitants of Norway

and Russia are as remarkable for their fine teeth as the

inhabitants of Africa. We observe fine teeth to be universal

likewise among the inhabitants of France, who live in a

_variable_ climate. These have been ascribed to their protecting

their heads from the action of the night air by means of woollen

night-caps, and to the extraordinary attention to the teeth of

their children. These precautions secure good teeth; and are

absolutely necessary in all variable climates, where people do

not adopt all the customs of the savage life.

The danger of many diseases is not proportioned to their violence, but

to their duration. America has advanced but a few paces in luxury and

effeminacy. There is yet strength enough in her vitals to give life to

those parts which are decayed. She may tread back her steps. For this

purpose,

I. Let our children be educated in a manner more agreeable to nature.

II. Let the common people (who constitute the wealth and strength of our

country) be preserved from the effects of ardent spirits. Had I a double

portion of all that eloquence which has been employed in describing the

political evils that lately threatened our country, it would be too

little to set forth the numerous and complicated _physical_ and _moral_

evils which these liquors have introduced among us. To encounter this

_hydra_ requires an arm accustomed, like that of Hercules, to vanquish

monsters. Sir William Temple tells us, that formerly in Spain no man

could be admitted as an evidence in a court, who had once been convicted

of drunkenness. I do not call for so severe a law in this country.

Let us first try the force of severe manners. Lycurgus governed more

by these, than by his laws. "Boni mores non bonæ leges," according to

Tacitus, were the bulwarks of virtue among the ancient Germans.

III. I despair of being able to call the votaries of Bacchus from their

bottle, and shall therefore leave them to be roused by the more eloquent

twinges of the gout.

IV. Let us be cautious what kind of manufactures we admit among us.

The rickets made their first appearance in the manufacturing towns in

England. Dr. Fothergill informed me, that he had often observed, when

a pupil, that the greatest part of the chronic patients in the London

Hospital were Spittal-field weavers. I would not be understood, from

these facts, to discourage those manufactures which employ women and

children: these suffer few inconveniences from a sedentary life: nor do

I mean to offer the least restraint to those manufactories among men,

which admit of free air, and the exercise of all their limbs. Perhaps

a pure air, and the abstraction of spiritous liquors, might render

sedentary employments less unhealthy in America, even among men, than in

the populous towns of Great-Britain.

The population of a country is not to be accomplished by rewards and

punishments. And it is happy for America, that the universal prevalence

of the protestant religion, the checks lately given to negro slavery,

the general unwillingness among us to acknowledge the usurpations of

primogeniture, the universal practice of inoculation for the small-pox,

and the absence of the plague, render the interposition of government

for that purpose unnecessary.

These advantages can only be secured to our country by AGRICULTURE.

This is the true basis of national health, riches, and populousness.

Nations, like individuals, never rise higher than when they are ignorant

whether they are tending. It is impossible to tell from history what

will be the effects of agriculture, industry, temperance, and commerce,

urged on by the competition of colonies, united in the same general

pursuits, in a country, which for extent, variety of soil, climate,

and number of navigable rivers, has never been equalled in any quarter

of the globe. America is the theatre where human nature will probably

receive her last and principal literary, moral, and political honours.

But I recall myself from the ages of futurity. The province of

Pennsylvania has already shown to her sister colonies, the influence

of agriculture and commerce upon the number and happiness of a people.

It is scarcely a hundred years since our illustrious legislator, with

a handful of men, landed upon these shores. Although the perfection

of our government, the healthiness of our climate, and the fertility

of our soil, seemed to ensure a rapid settlement of the province; yet

it would have required a prescience bordering upon divine, to have

foretold, that in such a short space of time, the province would contain

above 300,000 inhabitants; and that nearly 30,000 of this number

should compose a city, which should be the third, if not the second

in commerce in the British empire. The pursuits of literature require

leisure and a total recess from clearing forests, planting, building,

and all the common toils of settling a new country: but before these

arduous works were accomplished, the SCIENCES, ever fond of the company

of liberty and industry, chose this spot for the seat of their empire

in this new world. Our COLLEGE, so catholic in its foundation, and

extensive in its objects, already sees her sons executing offices in the

highest departments of society. I have now the honour of speaking in

the presence of a most respectable number of philosophers, physicians,

astronomers, botanists, patriots, and legislators; many of whom have

already seized the prizes of honour, which their ancestors had allotted

to a much later posterity. Our first offering had scarcely found its

way into the temple of fame, when the oldest societies in Europe turned

their eyes upon us, expecting with impatience to see the mighty fabric

of science, which, like a well-built arch, can only rest upon the

whole of its materials, completely finished from the treasures of this

unexplored quarter of the globe.

It reflects equal honour upon our society and the honourable assembly

of our province, to acknowledge, that we have always found the latter

willing to encourage by their patronage, and reward by their liberality,

all our schemes for promoting useful knowledge. What may we not expect

from this harmony between the sciences and government! Methinks I see

canals cut, rivers once impassable rendered navigable, bridges erected,

and roads improved, to facilitate the exportation of grain. I see the

banks of our rivers vying in fruitfulness with the banks of the river

of Egypt. I behold our farmers nobles; our merchants princes. But I

forbear--imagination cannot swell with the subject.

I beg leave to conclude, by deriving an argument from our connection

with the legislature, to remind my auditors of the duty they owe to the

society. Patriotism and literature are here connected together; and a

man cannot neglect the one, without being destitute of the other. Nature

and our ancestors have completed their works among us; and have left us

nothing to do, but to enlarge and perpetuate our own happiness.

AN ACCOUNT

OF THE

_CLIMATE OF PENNSYLVANIA_,

AND ITS

INFLUENCE UPON THE HUMAN BODY.

In order to render the observations upon the epidemic diseases which

compose the following volumes more useful, it will be necessary to

prefix to them a short account of the climate of Pennsylvania, and

of its influence upon the human body. This account may perhaps serve

further, to lead to future discoveries, and more extensive observations,

upon this subject.

The state of Pennsylvania lies between 39° 43' 25", and 42° north

latitude, including, of course, 2° 16' 35", equal to 157 miles from its

southern to its northern boundary. The western extremity of the state is

in the longitude of 5° 23' 40", and the eastern, is that of 27' from the

meridian of Philadelphia, comprehending in a due west course 311 miles,

exclusive of the territory lately purchased by Pennsylvania from the

United States, of which as yet no accurate surveys have been obtained.

The state is bounded on the south by part of the state of Delaware, by

the whole state of Maryland, and by Virginia to her western extremity.

The last named state, the territory lately ceded to Connecticut, and

Lake Erie, (part of which is included in Pennsylvania) form the western

and north-western boundaries of the state. Part of New-York, and the

territory lately ceded to Pennsylvania, with a part of Lake Erie,

compose the northern, and another part of New-York, with a large extent

of New-Jersey (separated from Pennsylvania by the river Delaware),

compose the eastern boundaries of the state. The lands which form these

boundaries (except a part of the states of Delaware, Maryland, and

New-Jersey) are in a state of nature. A large tract of the western and

north-eastern parts of Pennsylvania are nearly in the same uncultivated

situation.

The state of Pennsylvania is intersected and diversified with numerous

rivers and mountains. To describe, or even to name them all, would far

exceed the limits I have proposed to this account of our climate. It

will be sufficient only to remark, that one of these rivers, viz. the

Susquehannah, begins at the northern boundary of the state, twelve

miles from the river Delaware, and winding several hundred miles,

through a variegated country, enters the state of Maryland on the

southern line, fifty-eight miles westward of Philadelphia; that each

of these rivers is supplied by numerous streams of various sizes; that

tides flow in parts of two of them, viz. in the Delaware and Schuylkill;

that the rest rise and fall alternately in wet and dry weather; and

that they descend with great rapidity, over prominent beds of rocks in

many places, until they empty themselves into the bays of Delaware and

Chesapeak on the east, and into the Ohio on the western part of the

state.

The mountains form a considerable part of the state of Pennsylvania.

Many of them appear to be reserved as perpetual marks of the original

empire of nature in this country. The Allegany, which crosses the state

about two hundred miles from Philadelphia, in a north, inclining to

an eastern course, is the most considerable and extensive of these

mountains. It is called by the Indians the back-bone of the continent.

Its height, in different places, is supposed to be about 1,300 feet from

the adjacent plains.

The soil of Pennsylvania is diversified by its vicinity to mountains and

rivers. The vallies and bottoms consist of a black mould, which extends

from a foot to four feet in depth. But in general a deep clay forms the

surface of the earth. Immense beds of limestone lie beneath this clay

in many parts of the state. This account of the soil of Pennsylvania is

confined wholly to the lands on the east side of the Allegany mountain.

The soil on the west side of this mountain, shall be described in

another place.

The city of Philadelphia lies in the latitude of 39° 57', in longitude

75° 8' from Greenwich, and fifty-five miles west from the Atlantic ocean.

It is situated about four miles due north from the conflux of the rivers

Delaware and Schuylkill. The buildings, which consist chiefly of brick,

extend nearly three miles north and south along the Delaware, and

above half a mile due west towards the Schuylkill, to which river the

limits of the city extend, the whole of which includes a distance of

two miles from the Delaware. The land near the rivers, between the city

and the conflux of the rivers, is in general low, moist, and subject to

be overflowed. The greatest part of it is meadow ground. The land to

the northward and westward, in the vicinity of the city, is high, and

in general well cultivated. Before the year 1778, the ground between

the present improvements of the city, and the river Schuylkill, was

covered with woods. These, together with large tracts of wood to the

northward of the city, were cut down during the winter the British army

had possession of Philadelphia. I shall hereafter mention the influence

which the cutting down of these woods, and the subsequent cultivation of

the grounds in the neighbourhood of the city, have had upon the health

of its inhabitants.

The mean height of the ground on which the city stands, is about forty

feet above the river Delaware. One of the longest and most populous

streets in the city rises only a few feet above the river. The air at

the north is much purer than at the south end of the city; hence the

lamps exhibit a fainter flame in its southern than its northern parts.

The tide of the Delaware seldom rises more than six feet. It flows four

miles in an hour. The width of the river near the city is about a mile.

The city, with the adjoining districts of Southwark and the Northern

Liberties, contains between 70 and 80,000 inhabitants.

From the accounts which have been handed down to us by our ancestors,

there is reason to believe that the climate of Pennsylvania has

undergone a material change. Thunder and lightning are less frequent,

and the cold of our winters and heat of our summers are less uniform,

than they were forty or fifty years ago. Nor is this all. The springs

are much colder, and the autumns more temperate than formerly, insomuch

that cattle are not housed so soon by one month as they were in former

years. Within the last eight years, there have been some exceptions

to part of these observations. The winter of the year 1779-80, was

uniformly and uncommonly cold. The river Delaware was frozen near three

months during this winter, and public roads for waggons and sleighs

connected the city of Philadelphia in many places with the Jersey shore.

The thickness of the ice in the river near the city, was from sixteen

to nineteen inches, and the depth of the frost in the ground was from

four to five feet, according to the exposure of the ground, and the

quality of the soil. This extraordinary depth of the frost in the earth,

compared with its depth in more northern and colder countries, is

occasioned by the long delay of snow, which leaves the earth without

a covering during the last autumnal and the first winter months. Many

plants were destroyed by the intenseness of the cold during this winter.

The ears of horned cattle and the feet of hogs exposed to the air,

were frost-bitten; squirrels perished in their holes, and partridges

were often found dead in the neighbourhood of farm houses. The mercury

in January stood for several hours at 5° below 0, in Fahrenheit's

thermometer; and during the whole of this month (except on one day), it

never rose in the city of Philadelphia so high as to the freezing point.

The cold in the winter of the year 1783-4 was as intense, but not so

steady, as it was in the winter that has been described. It differed

from it materially in one particular, viz. there was a thaw in the month

of January, which opened all our rivers for a few days.

The summer which succeeded the winter of 1779-80, was uniformly warm.

The mercury in the thermometer, during this summer, stood on one day

(the 15th of August) at 95°, and fluctuated between 93°, and 80° for

many weeks. The thermometer, in every reference that has been, or shall

be made to it, stood in the shade in the open air.

I know it has been said by many old people, that the winters in

Pennsylvania are less cold, and the summers less warm, than they were

forty or fifty years ago. The want of thermometrical observations

before, and during those years, renders it difficult to decide this

question. Perhaps the difference of clothing and sensation between youth

and old age, in winter and summer, may have laid the foundation of this

opinion. I suspect the mean temperature of the air in Pennsylvania has

not altered, but that the principal change in our climate consists in

the heat and cold being less confined than formerly to their natural

seasons. I adopt the opinion of Doctor Williamson[30] respecting

the diminution of the cold in the southern, being occasioned by the

cultivation of the northern parts of Europe; but no such cultivation

has taken place in the countries which lie to the north-west of

Pennsylvania, nor do the partial and imperfect improvements which have

been made in the north-west parts of the state, appear to be sufficient

to lessen the cold, even in the city of Philadelphia. I have been able

to collect no facts, which dispose me to believe that the winters were

colder before the year 1740, than they have been since. In the memorable

winter of 1739-40, the Delaware was crossed on the ice, in sleighs, on

the 5th of March, old style, and did not open till the 13th of the same

month. The ground was covered during this winter with a deep snow, and

the rays of the sun were constantly obscured by a mist, which hung in

the upper regions of the air. In the winter of 1779-80, the river was

navigable on the 4th of March; the depth of the snow was moderate, and

the gloominess of the cold was sometime suspended for a few days by a

cheerful sun. From these facts, it is probable the winter of 1739-40 was

colder than the winter of 1779-80.

[30] American Philosophical Transactions, vol. I.

The winter of 1804-5 exhibited so many peculiarities that it deserves a

place in the history of the climate of Pennsylvania. The navigation of

the Delaware was obstructed on the 18th of December. The weather partook

of every disagreeable and distressing property of every cold climate on

the globe. These were intense cold, deep snows, hail, sleet, high winds,

and heavy rains. They generally occurred in succession, but sometimes

most of them took place in the course of four and twenty hours. A

serene and star-light evening, often preceded a tempestuous day. The

mercury stood for many days, in Philadelphia, at 4° and 6° above 0 in

Fahrenheit's thermometer. The medium depth of the snow was two feet,

but from its fall being accompanied with high winds, its height in many

places was three and four feet, particularly in roads, which it rendered

so impassable, as to interrupt business and social intercourse, in many

parts of the state. From the great depth of the snow, the ground was so

much protected from the cold, that the frost extended but six inches

below its surface. The newspapers daily furnished distressing accounts

of persons perishing with the cold by land and water, and of shipwrecks

on every part of the coast of the United States. Poultry were found

dead, or with frozen feet, in their coops, in many places.

This intense cold was not confined to Pennsylvania. In Norfolk, in

Virginia, the mercury stood at 18° above 0 on the 22d of January. At

Lexington, in Kentucky, it stood at 0 on the 21st of the same month.

In Lower Canada the snow was seven feet in depth, which is three feet

deeper than in common years. And such was the quantity of ice collected

in the northern seas, that a ship was destroyed, and several vessels

injured, by large masses of it, floating between the 41st and 42d

degrees of north latitude.

Great fears were entertained of an inundation in Pennsylvania, from

a sudden thaw of the immense quantities of snow and ice that had

accumulated during the winter, in every part of the state; but happily

they both dissolved away so gradually, as scarcely to injure a bridge or

a road. On the 28th of February the Delaware was navigable, and on the

2d of March no ice was to be seen in it.

Having premised these general remarks, I proceed to observe, that there

are seldom more than twenty or thirty days in summer or winter, in

Pennsylvania, in which the mercury rises above 80° in the former, or

falls below 30° in the latter season. Some old people have remarked,

that the number of _extremely_ cold and warm days in successive summers

and winters, bears an exact proportion to each other. This was strictly

true in the years 1787 and 1788.

The warmest part of the day in summer is at two, in ordinary, and at

three o'clock in the afternoon, in extremely warm weather. From these

hours, the heat gradually diminishes till the ensuing morning. The

coolest part of the four and twenty hours, is at the break of day.

There are seldom more than three or four nights in a summer in which

the heat of the air is nearly the same as in the preceding day. After

the warmest days, the evenings are generally agreeable, and often

delightful. The higher the mercury rises in the day time, the lower it

falls the succeeding night. The mercury at 80° generally falls to 68°,

while it descends, when at 60°, but to 56°. This disproportion between

the temperature of the day and night, in summer is always greatest in

the month of August. The dews at this time are heavy in proportion to

the coolness of the evening. They are sometimes so considerable as to

wet the clothes; and there are instances in which marsh-meadows, and

even creeks, which have been dry during the summer, have been supplied

with their usual waters from no other source, than the dews which have

fallen in this month, or in the first weeks of September.

There is another circumstance connected with the one just mentioned,

which contributes very much to mitigate the heat of summer, and that is,

it seldom continues more than two or three days without being succeeded

with showers of rain, accompanied sometimes by thunder and lightning,

and afterwards by a north-west wind, which produces a coolness in the

air that is highly invigorating and agreeable.

The warmest weather is _generally_ in the month of July. But intensely

warm days are often felt in May, June, August, and September. In the

annexed table of the weather for the year 1787, there is an exception to

the first of these remarks. It shows that the mean heat of August was

greater by a few degrees than that of July.

The transitions from heat to cold are often very sudden, and sometimes

to very distant degrees. After a day in which the mercury has stood at

86° and even 90°, it sometimes falls, in the course of a single night,

to the 65th, and even to the 60th degree, insomuch that fires have been

found necessary the ensuing morning, especially if the change in the

temperature of the air has been accompanied by rain and a south-east

wind. In a summer month, in the year 1775, the mercury was observed to

fall 20° in an hour and a half. There are few summers in which fires are

not agreeable during some parts of them. My ingenious friend, Mr. David

Rittenhouse, whose talent for accurate observation extends alike to all

subjects, informed me, that he had never passed a summer, during his

residence in the country, without discovering frost in every month of

the year, except July.

The weather is equally variable in Pennsylvania during the greatest

part of the winter. The mercury fell from 37° to 4-1/2° below 0 in four

and twenty hours, between the fourth and fifth of February, 1788. In

this season nature seems to play at cross purposes. Heavy falls of snow

are often succeeded in a few days by a general thaw, which frequently

in a short time leaves no vestige of the snow. The rivers Delaware,

Schuylkill, and Susquehannah have sometimes been frozen (so as to bear

horses and carriages of all kinds) and thawed so as to be passable in

boats, two or three times in the course of the same winter. The ice is

formed for the most part in a gradual manner, and seldom till the water

has been previously chilled by a fall of snow. Sometimes its production

is more sudden. On the night of the 31st of December, 1764, the Delaware

was completely frozen over between ten o'clock at night and eight the

next morning, so as to bear the weight of a man. An unusual vapour like

a fog was seen to rise from the water, in its passage from a fluid to a

solid state.

This account of the variableness of the weather in winter, does not

apply to every part of Pennsylvania. There is a line about the 41° of

the state, beyond which the winters are steady and regular, insomuch

that the earth there is seldom without a covering of snow during the

three winter months. In this line the climate of Pennsylvania forms a

union with the climate of the eastern and northern states.

The time in which frost and ice begin to show themselves in the

neighbourhood of Philadelphia, is generally about the latter end of

October or the beginning of November. But the intense cold seldom sets

in till about the the 20th or 25th of December; hence the common saying,

"as the day lengthens, the cold strengthens." The coldest weather is

commonly in January. The navigation of the river Delaware, after being

frozen, is seldom practicable for large vessels, before the first week

in March.

As in summer there are often days in which fires are agreeable, so there

are sometimes days in winter in which they are disagreeable. Vegetation

has been observed in all the winter months. Garlic was tasted in butter

in January, 1781. The leaves of the willow, the blossoms of the peach

tree, and the flowers of the dandelion and the crocus, were all seen in

February, 1779; and I well recollect, when a school-boy, to have seen an

apple orchard in full bloom, and small apples on many of the trees, in

the month of December.

A cold day in winter is often succeeded by a moderate evening. The

coldest part of the four and twenty hours, is generally at the break of

day.

In the most intense cold which has been recorded in Philadelphia, within

the last twenty years, the mercury stood at 5° below 0. But it appears

from the accounts published by Messieurs Mason and Dixon, in the 58th

volume of the Transactions of the Royal Society of London, that the

mercury stood at 22° below 0, on the 2d of January, 1767, at Brandywine,

about thirty miles to the westward of Philadelphia. They inform us, that

on the 1st of the same month, the mercury stood at 20°, and on the day

before at 7° below 0. I have to lament that I am not able to procure any

record of the temperature of the air in the same year in Philadelphia.

From the variety in the height and quality of the soil, and from the

difference in the currents of winds and the quantity of rain and snow

which fall in different parts of the state, it is very probable this

excessive cold may not have extended thirty miles from the place where

it was first perceived.

The greatest degree of heat upon record in Philadelphia, is 95°.

The standard temperature of the air in the city of Philadelphia is

52-1/2°, which is the temperature of our deepest wells, as also the mean

heat of our common spring water.

The spring in Pennsylvania is generally less pleasant than in many other

countries. In March the weather is stormy, variable, and cold. In April,

and sometimes in the beginning of May, it is moist, and accompanied by

a degree of cold which has been called _rawness_, and which, from its

disagreeable effects upon the temper, has been called the _sirocco_ of

this country. From the variable nature of the weather in the spring,

vegetation advances very differently in different years. The colder the

spring, the more favourable it proves to the fruits of the earth. The

hopes of the farmer from his fruit-trees in a warm spring are often

blasted by a frost in April and May. A fall of snow is remembered with

regret by many of them, on the night between the 3d and 4th of May, in

the year 1774; also on the morning of the 8th of May, 1803. Such was its

quantity on the latter day, that it broke down the limbs of many poplar

trees. This effect was ascribed to its not being accompanied with any

wind. The colder the winter, the greater delay we generally observe in

the return of the ensuing spring.

Sometimes the weather during the spring months is cloudy and damp,

attended occasionally with a gentle fall of rain resembling the spray

from a cataract of water. A day of this kind of weather is called, from

its resemblance to a damp day in Great-Britain, "an English day." This

damp weather seldom continues more than three or four days. The month of

May, 1786, will long be remembered, for having furnished a very uncommon

instance of the absence of the sun for fourteen days, and of constant

damp or rainy weather.

The month of June is the only month in the year which resembles a

spring month in the southern countries of Europe. The weather is then

generally temperate, the sky is serene, and the verdure of the country

is universal and delightful.

The autumn is the most agreeable season in the year in Pennsylvania.

The cool evenings and mornings, which generally begin about the first

week in September, are succeeded by a moderate temperature of the air

during the day. This kind of weather continues with an increase of cold

scarcely perceptible, till the middle of October, when the autumn is

closed by rain, which sometimes falls in such quantities as to produce

destructive freshes in the rivers and creeks, and sometimes descends

in gentle showers, which continue, with occasional interruptions by a

few fair days, for two or three weeks. These rains are the harbingers

of the winter; and the Indians have long ago taught the inhabitants

of Pennsylvania, that the degrees of cold during the winter, are in

proportion to the quantity of rain which falls during the autumn[31].

[31] I cannot help agreeing with Mr. Kirwan, in one of his remarks

upon the science of meteorology, in the preface to his estimate

of the temperature of different latitudes. "This science (says

he), if brought to perfection, would enable us at least to

foresee those changes in the weather which we could not prevent.

Great as is the distance between such knowledge and our own

present attainments, we have no reason to think it above the

level of the powers of the human mind. The motions of the

planets must have appeared as perplexed and intricate to those

who first contemplated them; yet, by persevering industry, they

are now known to the utmost precision. The present is (as the

great Leibnitz expresses it) in every case pregnant with the

future, and the connection must be found by long and attentive

observation."

The influence which the perfection of this science must have upon

health, agriculture, navigation, and commerce, is too obvious to

be mentioned.

From this account of the temperature of the air in Pennsylvania, it

is evident that there are seldom more than four months in which the

weather is agreeable without a fire.

In winter the winds generally come from the north-west in _fair_,

and from the north-east in _wet_ weather. The north-west winds are

uncommonly dry as well as cold. It is in consequence of the violent

action of these winds that trees have uniformly a thicker and more

compact bark on their northern than on their southern exposures. Even

brick houses are affected by the force and dryness of these north-west

winds: hence it is much more difficult to demolish the northern than the

southern walls of an old brick house. This fact was communicated to me

by an eminent bricklayer in the city of Philadelphia.

The winds in fair weather in the spring, and in warm weather in the

summer, blow from the south-west and from west-north-west. The _raw_

air before-mentioned comes from the north-east. The south-west winds

likewise usually bring with them those showers of rain in the spring

and summer which refresh the earth. They moreover moderate the heat of

the weather, provided they are succeeded by a north-west wind. Now and

then showers of rain come from the west-north-west.

There is a common fact connected with the account of the usual winds in

Pennsylvania, which it may not be improper to mention in this place.

While the clouds are seen flying from the south-west, the _scud_, as it

is called, or a light vapour, is seen at the same time flying below the

clouds from the north-east.

The moisture of the air is much greater than formerly, occasioned

probably by the exhalations which in former years fell in the form of

snow, now descending in the form of rain. The depth of the snow is

sometimes between two and three feet, but in general seldom exceeds

between six and nine inches.

Hail frequently descends with snow in winter. Once in four or five years

large and heavy showers of hail fall in the spring and summer. They

generally run in narrow veins (as they are called) of thirty or forty

miles in length, and two or three miles in breadth. The heaviest shower

of hail that is remembered in Philadelphia, did not extend in breadth

more than half a mile north and south. Some of the stones weighed half

an ounce. The windows of many houses were broken by them. This shower

fell in May, 1783.

From sudden changes in the air, rain and snow often fall together,

forming what is commonly called _sleet_.

In the uncultivated parts of the state, the snow sometimes lies on the

ground till the first week in April. The backwardness of the spring has

been ascribed to the passage of the air over the undissolved beds of

snow and ice which usually remain, after the winter months are past,

on the north-west grounds and waters of the state, and of the adjacent

country.

The dissolution of the ice and snow in the spring is sometimes so sudden

as to swell the creeks and rivers in every part of the state to such a

degree, as not only to lay waste the hopes of the husbandman from the

produce of his lands, but in some instances to sweep his barns, stables,

and even his dwelling house into their currents[32]. The wind, during a

general thaw, comes from the south-west or south-east.

[32] The following account of the thaw of the river Susquehannah, in

the spring of 1784, was published by the author in the Columbian

Magazine, for November, 1786. It may serve to illustrate a fact

related formerly in the history of the winters in Pennsylvania,

as well as to exhibit an extraordinary instance of the

destructive effects of a sudden thaw.

"The winter of 1783-4 was uncommonly cold, insomuch that the

mercury in Fahrenheit's thermometer stood several times at 5

degrees below 0. The snows were frequent, and, in many places,

from two to three feet deep, during the greatest part of the

winter. All the rivers in Pennsylvania were frozen, so as to

bear waggons and sleds with immense weights. In the month of

January a thaw came on suddenly, which opened our rivers so as to

set the ice a-driving, to use the phrase of the country. In the

course of one night, during the thaw, the wind shifted suddenly

to the north-west, and the weather became intensely cold. The

ice, which had floated the day before, was suddenly obstructed;

and in the river Susquehannah, the obstructions were formed in

those places where the water was most shallow, or where it had

been accustomed to fall. This river is several hundred miles in

length, and from half a mile to a mile and a half in breadth, and

winds through a hilly, and in many places a fertile and highly

cultivated country. It has as yet a most difficult communication

with our bays and the sea, occasioned by the number and height

of the falls which occur near the mouth of the river. The ice in

many places, especially where there were falls, formed a kind

of dam, of a most stupendous height. About the middle of March

our weather moderated, and a thaw became general. The effects

of it were remarkable in all our rivers; but in none so much as

in the river I have mentioned. I shall therefore endeavour in a

few words to describe them. Unfortunately the dams of ice did

not give way all at once, nor those which lay nearest to the

mouth of the river, first. While the upper dams were set afloat

by the warm weather, the lower ones, which were the largest, and

in which, of course, the ice was most impacted, remained fixed.

In consequence of this, the river rose in a few hours, in many

places, above 30 feet, rolling upon its surface large lumps of

ice, from 10 to 40 cubic feet in size. The effects of this sudden

inundation were terrible. Whole farms were laid under water.

Barns, stables, horses, cattle, fences, mills of every kind, and,

in one instance, a large stone house, 40 by 30 feet, were carried

down the stream. Large trees were torn up by the roots; several

small islands, covered with woods, were swept away, and not a

vestige of them was left behind. On the barns which preserved

their shape, in some instances, for many miles were to be seen

living fowls; and, in one dwelling, a candle was seen to burn

for some time, after it was swept from its foundation. Where the

shore was level, the lumps of ice, and the ruins of houses and

farms, were thrown a quarter of a mile from the ordinary height

of the river. In some instances, farms were ruined by the mould

being swept from them by the cakes of ice, or by depositions of

sand; while others were enriched by large depositions of mud.

The damage, upon the whole, done to the state of Pennsylvania by

this fresh, was very great. In most places it happened in the day

time, or the consequences must have been fatal to many thousands."

"I know of but one use that can be derived from recording the

history of this inundation. In case of similar obstructions of

rivers, from the causes such as have been described, the terrible

effects of their being set in motion by means of a general thaw

may in part be obviated, by removing such things out of the

course of the water and ice as are within our power; particularly

cattle, hay, grain, fences, and farming utensils of all kinds."

The air, when dry in Pennsylvania, has a peculiar elasticity, which

renders the heat and cold less insupportable than the same degrees of

both are in moister countries. It is in those cases only when summer

showers are not succeeded by north-west winds, that the heat of the air

becomes oppressive and distressing, from being combined with moisture.

From tradition, as well as living observation, it is evident, that

the waters in many of the creeks in Pennsylvania have diminished

considerably within the last fifty years. Hence many mills, erected

upon large and deep streams of water, now stand idle in dry weather;

and many creeks, once navigable in large boats, are now impassable even

in canoes. This diminution of the waters has been ascribed to the

application of a part of them to the purpose of making meadows.

The mean elevation of the barometer in Philadelphia, is about 30 inches.

The variations in the barometer are very inconsiderable in the greatest

changes of the weather, which occur in the city of Philadelphia. During

the violent and destructive storm which blew from the south-west on

the 11th of November, 1788, it suddenly fell from 30 to 29-3/10. Mr.

Rittenhouse informs me, that long and faithful observations have

satisfied him, that the alterations in the height of the mercury in the

barometer do not _precede_ but always _succeed_ changes in the weather.

It falls with the south and south-west, and rises with the north and

north-west winds.

The quantity of water which falls in rain and snow, one year with

another, amounts to from 24 to 36 inches. But to complete the account

of variable qualities in the climate, it will be necessary to add, that

our summers and autumns are sometimes marked by a _deficiency_, and

sometimes by an _excessive_ quantity of rain. The summer and autumn

of 1782 were uncommonly dry. Near two months elapsed without a single

shower of rain. There were only two showers in the whole months of

September and October. In consequence of this dry weather, there was

no second crop of hay. The Indian corn failed of its increase in many

places, and was cut down for food for cattle. Trees newly planted, died.

The pasture fields not only lost their verdure, but threw up small

clouds of dust when agitated by the feet of men, or beasts. Cattle in

some instances were driven many miles to be watered, every morning

and evening. It was remarked during this dry weather, that the sheep

were uncommonly fat, and their flesh well tasted, while all the other

domestic animals languished from the want of grass and water. The earth

became so inflammable in some places, as to burn above a foot below

its surface. A complete consumption of the turf by an accidental fire

kindled in the adjoining state of New-Jersey, spread terror and distress

through a large tract of country. Springs of water and large creeks

were dried up in many parts of the state. Rocks appeared in the river

Schuylkill, which had never been observed before, by the oldest persons

then alive. On one of them were cut the figures 1701. The atmosphere,

during part of this dry weather, was often filled, especially in

the mornings, with a thin mist, which, while it deceived with the

expectation of rain, served the valuable purpose of abating the heat

of the sun. A similar mist was observed in France by Dr. Franklin, in

the summer of 1782. The winter which succeeded it was uncommonly cold

in France, as well as in Pennsylvania. I am sorry that I am not able

to furnish the mean heat of each of the summer months. My notes of the

weather enable me to add nothing further upon this subject, than that

the summer was "uncommonly cool."

The summer of the year 1788 afforded a remarkable instance of _excess_

in the quantity of rain which sometimes falls in Pennsylvania. Thirteen

days are marked with rain in July, in the records of the weather kept

at Spring-Mill. There fell on the 18th and 19th of August seven inches

of rain in the city of Philadelphia. The wheat suffered greatly by the

constant rains of July in the eastern and middle parts of the state. So

unproductive a harvest in grain, from wet weather, had not been known,

it is said, in the course of the last 70 years. The heat of the air,

during these summer months was very moderate. Its mean temperature at

Spring-Mill was 67,8 in June, 74,7 in July, and only 70,6 in August.

It is some consolation to a citizen of Pennsylvania, in recording

facts which seem to militate against our climate, to reflect that the

difference of the weather, in different parts of the state, at the

same season, is happily accommodated to promote an increase of the same

objects of agriculture; and hence a deficiency of crops has never been

known in any one year throughout the _whole_ state.

The aurora borealis and meteors are seen occasionally in Pennsylvania.

In the present imperfect state of our knowledge of their influence upon

the human body, it will be foreign to the design of this history of our

climate to describe them.

Storms and hurricanes are not unknown in Pennsylvania. They occur once

in four or five years, but they are most frequent and destructive in the

autumn. They are generally accompanied by rain. Trees are torn up by

the roots, and the rivers and creeks are sometimes swelled so suddenly

as to do considerable damage to the adjoining farms. The wind, during

these storms, generally blows from the south-east and south-west. In the

storms which occurred in September, 1769, and in the same month of the

year 1785, the wind veered round contrary to its usual course, and blew

from the north.

After what has been said, the character of the climate of Pennsylvania

may be summed up in a few words. There are no two successive years

alike. Even the same successive seasons and months differ from each

other every year. Perhaps there is but one steady trait in the character

of our climate, and that is, it is uniformly variable.

To furnish the reader with a succinct view of the weather in

Pennsylvania, that includes all the articles that have been mentioned,

I shall here sub-join a table containing the result of meteorological

observations made near the river Schuylkill, for one year, in the

neighbourhood of Philadelphia, by an ingenious French gentleman, Mr.

Legeaux, who divides his time between rural employments, and useful

philosophical pursuits. This table is extracted from the Columbian

Magazine, for February, 1788. The height of Spring-Mill above the city

of Philadelphia, is supposed to be about 70 feet.

|====================================================================|

| METEOROLOGICAL OBSERVATIONS, made at SPRING-MILL, |

| 13 miles NNW of Philadelphia. Result of the year 1787. |

|====================================================================|

| | THERMOMETER. | BAROMETER. | PREVAILING |

| | of | de | | WIND. |

| MONTH. |_Fahrenheit_,| _Reaumur_, | mean height | |

| | mean degree |degrés moyens| | |

| | D. 1/16 O | D. 1/10 O |in. pts. 1/16| |

|----------+-------------+-------------+-------------+---------------|

|January | 35 1 | 1 4 | 29 9 9 |Variable still |

|February | 33 8 | 8 | 29 9 9 |NE |

|March | 45 1 | 5 8 | 29 9 7 |W |

|April | 54 3 | 9 9 | 29 9 6 |Still, SW |

|May | 61 2 | 13 | 29 9 2 |Still, WSW |

|June | 70 7 | 17 2 | 29 8 2 |WNW |

|July | 72 2 | 17 9 | 29 9 10 |WWSW var. |

|August | 74 5 | 18 9 | 29 10 6 |W |

|September | 64 7 | 14 5 | 29 10 4 |WNW |

|October | 51 1 | 8 5 | 29 11 9 |WNW vari. |

|November | 45 1 | 5 8 | 29 11 1 |Still, vari. |

|December | 34 | 9 | 29 7 7 |WNW |

|----------+-------------+-------------+-------------+---------------|

| |10 Feb. |10 Feb. D. du| 8 Mar. | |

| RESULT. |greatest D. |plus. gr. | greatest | |

| |of cold. |froid. | elevation. | |

| | 5 | 12 0 | 30 10 | |

| |-------------+-------------+-------------| |

| |3 July |3 July plus |2 Febr. least| WNW |

| |greatest D. |G. D. de |elevation. | |

| |of heat. |chaud. | | |

| | 96 1 | 28 5 | 29 | |

| |-------------+-------------+-------------| |

| |Variation. | Variation. |Variation. | |

| | 91 1 | 40 5 | 1 10 | |

|----------|-------------+-------------+-------------|---------------|

| |Temperature. |Temperature. |Mean elevat. | |

| | 53 5 | 9 6 | 20 9 9 | |

|====================================================================|

| MONTH. | DAYS of | WATER | WEATHER. Key for left |

| | [Key | of RAIN | A=aur. bor. |

| | at right] | and SNOW. | R=rain Th=thunder |

| |A|R |Th|S |T|in. pts. 1/16| S=snow T=tempest |

|----------+-+--+--+--+-+-------------+------------------------------|

|January | | 7| 1| 4| | 3 10 10 |Fair, still, cold, and snow. |

|February | | 3| | 3|2| 3 7 3 |Fair, overcast. |

|March | | 6| | 3| | 2 4 2 |Fair, windy. |

|April | | 3| 2| 1|2| 1 2 13 |Fair, and very dry. |

|May |1|14| 6| |2| 4 11 4 |Foggy, cold, and wet. |

|June | | 9| 1| | | 1 10 4 |Very fair & growing weather. |

|July |1| 5| 2| | | 3 1 11 |Fair, and overcast. |

|August | |11| 4| |1| 5 2 3 |Very fair, and cloudy. |

|September | | 6| 1| |1| 2 7 8 |Fair weather. |

|October |1| 4| | | | 7 10 |Foggy, fair, and dry weather. |

|November |1| 5| | | | 2 6 10 |Very fair. |

|December | | | | 1|1| 9 |Very fair, and very dry. |

|----------+-+--+--+--+-+-------------+------------------------------|

| RESULT. |4|73|17|12|9|32 8 14 |TEMPERATURE OF THE YEAR 1787. |

| | | | Very fair, dry, abundant in |

| | | | every thing, and healthy. |

|====================================================================|

It is worthy of notice, how near the mean heat of the year, and of the

month of April, in two successive years, are to each other in the same

place. The mean heat of April, 1787, was 54°3, that of April, 1788,

was 52°2. By the table of the mean heat of each month in the year, it

appears that the mean heat of 1787 was 53°5 at Spring-Mill.

The following accounts of the climates of Pekin and Madrid, which lie

within a few minutes of the same latitude as Philadelphia, may serve to

show how much climates are altered by local and relative circumstances.

The account of the temperature of the air at Pekin will serve further to

show, that with all the advantages of the highest degrees of cultivation

which have taken place in China, the winters are colder, and the summers

warmer there than in Pennsylvania, principally from a cause which will

probably operate upon the winters of Pennsylvania for many centuries to

come, viz. the vicinity of an uncultivated north-west country.

"PEKIN, lat. 39° 54', long. 116° 29' W.

"By five years observations, its annual mean temperature was found to be

55° 5'.

January 20°,75 July 84°,8

February 32 August 83

March 48 September 63

April 59 October 52

May 72 November 41

June 83°,75 December 27

"The temperature of the Atlantic under this parallel is 62, but the

standard of this part of the globe is the North Pacific, which is here

4 or 5 degrees colder than the Atlantic. The Yellow Sea is the nearest

to Pekin, being about 200 miles distant from it; but it is itself cooled

by the mountainous country of Corea, which interposes between it and the

ocean, for a considerable part of its extent. Besides, all the northern

parts of China (in which Pekin lies) must be cooled by the vicinity of

the mountains of Chinese Tartary, among which the cold is said to be

excessive.

"The greatest cold usually experienced during this period was 5°, the

greatest heat, 98°: on the 25th of July, 1773, the heat arose to 108°

and 110°: a N. E. or N. W. wind produces the greatest cold, a S. or S.

W. or S. E. the greatest heat[33]."

[33] "6. Mem. Scav. Etrang. p. 528."

"MADRID, lat. 40° 25', long. 3° 20' E.

The usual heat in summer is said to be from 75° to 85°; even at night it

seldom falls below 70°; the mean height of the barometer is 27,96. It

seems to be about 1900 feet above the level of the sea[34]."

[34] "Mem. Par. 1777, p. 146."

The above accounts are extracted from Mr. Kirwan's useful and elaborate

estimate of the temperature of different latitudes.

The history which has been given of the climate of Pennsylvania, is

confined chiefly to the country on the east side of the Allegany

mountain. On the west side of this mountain, the climate differs

materially from that of the south-eastern parts of the state in the

temperature of the air, in the effects of the winds upon the weather,

and in the quantity of rain and snow which falls every year. The winter

seldom breaks up on the mountains before the 25th of March. A fall of

snow was once perceived upon it, which measured an inch and a half, on

the 11th day of June. The trees which grow upon it are small, and Indian

corn is with difficulty brought to maturity, even at the foot of the

east side of it. The south-west winds on the west side of the mountain

are accompanied by cold and rain. The soil is rich, consisting of near

a foot, in many places, of black mould. The roads in this country are

muddy in winter, but seldom dusty in summer. The arrangement of strata

of the earth on the west side, differs materially from their arrangement

on the east side the mountain. "The country (says Mr. Rittenhouse, in a

letter to a friend in Philadelphia[35]), when viewed from the western

ridge of the Allegany, appears to be one vast extended plain. All the

various strata of stone seem to lie undisturbed in the situation in

which they were first formed, and the layers of stone, sand, clay, and

coal, are nearly _horizontal_."

[35] Columbian Magazine, for October, 1786.

The temperature of the air on the west is seldom so hot, or so cold,

as on the east side of the mountain. By comparing the state of a

thermometer examined by Dr. Bedford at Pittsburg, 284 miles from

Philadelphia, it appears that the weather was not so cold by twelve

degrees in that town, as it was in Philadelphia, on the 5th of February,

1788.

To show the difference between the weather at Spring-Mill and in

Pittsburg, I shall here sub-join an account of it, in both places, the

first taken by Mr. Legeaux, and the other by Doctor Bedford.

+----------------------------------------------------------+

| METEOROLOGICAL OBSERVATIONS, made at SPRING-MILL, |

| 13 miles NNW. of Philadelphia. April, 1788. |

+-------+------------------------+-------------+-----------+

| | | | |

| | | | |

| | | | |

| | | | |

| | THERMOMETER | | |

| |-------------+----------| BAROMETER. | |

| | of | de | | |

| |_Fahrenheit_,|_Reaumur_,| mean | |

| D. | mean | degrés | height | |

| of the| degree | moyens | |PREVAILING |

| month.| D. 1/10 O | D. 1/10 O|in. pts. 1/10| WIND. |

+-------+-------------+--------+-+-------------+-----------+

| 1 | 58 1 | | 11 6 | | 29 10 5 |W. |

| 2 | 46 9 | | 6 9 | | 30 1 |Calm. |

| 3 | 40 3 | | 3 7 | | 30 3 |Changeable.|

| 4 | 51 3 | | 8 6 | | 29 11 7 |SW. |

| 5 | 51 1 | | 8 5 | | 30 7 |E. |

| 6 | 55 7 | | 10 5 | | 29 11 7 |Calm. |

| 7 | 51 3 | | 8 6 | | 30 2 |NE. |

| 8 | 42 1 | | 4 5 | | 29 11 |E. |

| 9 | 63 5 | | 14 | | 29 8 |W. |

| 10 | 46 7 | | 6 5 | | 29 10 |W. |

| 11 | 53 8 | | 9 7 | | 30 2 |W. |

| 12 | 44 5 | | 5 5 | | 29 10 |Calm. |

| 13 | 60 5 | | 12 7 | | 29 10 3 |SW. |

| 14 | 50 2 | | 8 1 | | 29 9 |E. |

| 15 | 58 1 | | 11 6 | | 29 9 7 |SW. |

+-------+----- --+---+-- -----+-+-------------+-----------+

| METEOROLOGICAL OBSERVATIONS, made at PITTSBURG, |

| 284 miles west of Philadelphia. April, 1788. |

+-------+---------+---+--------+-+-------------+-----------+

| 1 | 46 | | | | |SW. |

| 2 | 42 | | | | |NE. by N. |

| 3 | 43 | | | | |SE. |

| 4 | 64 | | | | |Calm. |

| 5 | 80 | | | | |SE. by S. |

| 6 | 52 | | | | |SW. |

| 7 | 48 | | | | |NE. by N. |

| 8 | 66 | | | | |SE. by S. |

| 9 | 56 | | | | |NW. by N. |

| 10 | 60 | | | | |SW. |

| 11 | 62 | | | | |Calm. |

| 12 | 67 | | | | |SW. |

| 13 | 62 | | | | |Calm. |

| 14 | 60 | | | | |Variable. |

| 15 | 52 | | | | |W. |

+-------+---------+---+--------+-+-------------+-----------+

+------------------------------------------------------+

| METEOROLOGICAL OBSERVATIONS, made at SPRING-MILL, |

| 13 miles NNW. of Philadelphia. April, 1788. |

+-------+-----------------------+----------------------+

| | DAYS of | |

| |aur. boreal. | |

| | |rain. | |

| | | |thunder. | |

| | | | |snow. | |

| | | | | | +-------------| |

| | | | | | | WATER. | |

| D. | | | | | | of RAIN | |

| of the| | | | | | and SNOW. | |

| month.| | | | | |in. pts. 1/16| WEATHER. |

+-------+-+-+-+-+-+-------------+----------------------+

| 1 | | | | | | |Overcast, fair. |

| 2 | | | | | | |Overcast and windy. |

| 3 | |1| | | | 1 15 |Overcast, rainy. |

| 4 | | | | | | |Overcast. |

| 5 | | | | | | |Overcast, fair. |

| 6 | |1| | | | 1 3 |Overcast, rainy. |

| 7 | |1| | | | 2 7 |Overcast, rainy. |

| 8 | |1| | | | 1 4 |Rainy. |

| 9 | | | | | | |Overcast, windy. |

| 10 | | | | | | |Fair. |

| 11 | | | | | | |Very fair. |

| 12 | |1| | | | 1 11 |Overcast, rainy. |

| 13 | | | | | | |Very fair. |

| 14 | |1| | | | 1 14 |Fair, overcast, rainy.|

| 15 | |1| | | | 2 13 |Foggy, rainy. |

+-------+-+-+-+-+-+-------------+----------------------+

| METEOROLOGICAL OBSERVATIONS, made at PITTSBURG, |

| 284 miles west of Philadelphia. April, 1788. |

+-------+-+-+-+-+-+-------------+----------------------+

| 1 | |1| | | | |Cloudy. |

| 2 | | | | | | |Clear. |

| 3 | |1| | | | |Cloudy. |

| 4 | | | | | | |Clear. |

| 5 | |1|1| | | |Cloudy. |

| 6 | |1| | | | |Cloudy. |

| 7 | | | | | | |Cloudy. |

| 8 | |1|1| | | |Cloudy. |

| 9 | | | | | | |Cloudy. |

| 10 | | | | | | |Cloudy, with wind. |

| 11 | | | | | | |Clear. |

| 12 | | | | | | |Cloudy, with wind. |

| 13 | | | | | | |Clear. |

| 14 | |1| | | | |Cloudy. |

| 15 | | | | | | |Cloudy. |

+-------+-+-+-+-+-+-------------+----------------------+

From a review of all the facts which have been mentioned, it appears

that the climate of Pennsylvania is a compound of most of the climates

in the world. Here we have the moisture of Britain in the spring, the

heat of Africa in summer, the temperature of Italy in June, the sky of

Egypt in the autumn, the cold and snows of Norway and the ice of Holland

in the winter, the tempests (in a certain degree) of the West-Indies in

every season, and the variable winds and weather of Great-Britain in

every month of the year.

From this history of the climate of Pennsylvania, it is easy to

ascertain what degrees of health, and what diseases prevail in the

state. As we have the climates, so we have the health, and the acute

diseases, of all the countries that have been mentioned. Without

attempting to enumerate the diseases, I shall only add a few words upon

the _time_ and _manner_ in which they are produced.

I. It appears from the testimonies of many aged persons, that pleurisies

and inflammatory diseases of all kinds, are less frequent now than they

were forty or fifty years ago.

II. It is a well known fact, that intermitting and bilious fevers

have increased in Pennsylvania in proportion as the country has been

_cleared of its wood_, in many parts of the state.

III. It is equally certain that these fevers have lessened, or

disappeared, in proportion as the country has been _cultivated_.

IV. Heavy rains and freshes in the spring seldom produce fevers, unless

they are succeeded by unseasonably warm weather.

V. Sudden changes from great heat to cold, or cool weather, if they

occur before the 20th of August, seldom produce fevers. After that time,

they are generally followed by them.

VI. The same state of the atmosphere, whether cold or warm, moist or

dry, continued for a long time, without any material changes, is always

healthy. Acute and inflammatory fevers were in vain looked for in the

cold winter of 1779-80. The dry summer of 1782, and the wet summer of

1788, were likewise uncommonly healthy in the city of Philadelphia.

These facts extend only to those diseases which depend upon the sensible

qualities of the air, for diseases from miasmata and contagion, are less

influenced by the uniformity of the weather. The autumn of 1780 was very

sickly in Philadelphia, from the peculiar situation of the grounds in

the neighbourhood of the city, while the country was uncommonly healthy.

The dry summer and autumn of 1782 were uncommonly sickly in the country,

from the extensive sources of morbid exhalations which were left by the

diminution of the waters in the creeks and rivers.

VII. Diseases are often _generated_ in one season and _produced_ in

another. Hence we frequently observe fevers of different kinds to

_follow_ every species of the weather that was mentioned in the last

observation.

VIII. The excessive heat in Pennsylvania has sometimes proved fatal to

persons who have been much exposed to it. Its morbid effects discover

themselves by a difficulty of breathing, a general languor, and, in

some instances, by a numbness and an immobility of the extremities. The

excessive cold in Pennsylvania has more frequently proved fatal, but it

has been chiefly to those persons who have sought a defence from it,

by large draughts of spiritous liquors. Its operation in bringing on

sleepiness previous to death, is well known. On the 5th of February,

1788, many people were affected by the cold. It produced a violent

pain in the head; and, in one instance, a sickness at the stomach,

and a vomiting appeared to be the consequence of it. I have frequently

observed that a greater number of old people die, during the continuance

of extreme cold and warm weather, than in the same number of days in

moderate weather.

IX. May and June are usually the healthiest months in the year.

X. The influence of the winds upon health, depends very much upon the

nature of the country over which they pass. Winds which pass over

mill-dams and marshes in August and September, generally carry with them

the seeds of fevers.

XI. The country in the neighbourhood of Philadelphia was formerly more

sickly than the central parts of the city, after the 20th of August.

Since the year 1793, the reverse of this has been the case.

XII. The night-air is always unwholesome from the 20th of August,

especially during the passive state of the system in _sleep_. The

frequent and sudden changes of the air from heat to cold render it

unsafe to sleep with open windows, during the autumnal months.

XIII. Valetudinarians always enjoy the most health in Pennsylvania in

the summer and winter months. The spring, in a particular manner, is

very unfavourable to them.

I shall conclude the account of the influence of the climate of

Pennsylvania upon the human body, with the following observations.

1. The sensations of heat and cold are influenced so much by outward

circumstances, that we often mistake the degrees of them by neglecting

to use such conveniences as are calculated to obviate the effects of

their excess. A native of Jamaica often complains less of the heat, and

a native of Canada of the cold, in their respective countries, than they

do under certain circumstances in Pennsylvania. Even a Pennsylvanian

frequently complains less of the heat in Jamaica, and of the cold in

Canada, than in his native state. The reason of this is plain. In

countries where heat and cold are intense and regular, the inhabitants

guard themselves, by accommodating their houses and dresses to each of

them. The instability and short duration of excessive heat and cold in

Pennsylvania, have unfortunately led its inhabitants, in many instances,

to neglect adopting customs, which are used in hot and cold countries

to guard against them. Where houses are built with a southern or

south-western front exposure, and where other accommodations to the

climate are observed in their construction, the disagreeable excesses

of heat and cold are rendered much less perceptible in Pennsylvania.

Perhaps the application of the principles of philosophy and taste to the

construction of our houses, within the last thirty or forty years, may

be another reason why some old people have supposed that the degrees of

heat and cold are less in Pennsylvania than they were in former years.

2. The variable nature of the climate of Pennsylvania does not render

it _necessarily_ unhealthy. Doctor Huxham has taught us, that the

healthiest seasons in Great-Britain have often been accompanied by the

most variable weather. His words upon this subject convey a reason for

the fact. "When the constitutions of the year are frequently changing,

so that by the _contrast_ a sort of _equilibrium_ is kept up, and health

with it; and that especially if persons are careful to guard themselves

well against these sudden changes[36]." Perhaps no climate or country is

unhealthy, where men acquire from experience, or tradition, the arts of

accommodating themselves to it. The history of all the nations of the

world, whether savage, barbarous, or civilized, previously to a mixture

of their manners by an intercourse with strangers, seems to favour this

opinion. The climate of China appears, in many particulars, to resemble

that of Pennsylvania. The Chinese wear loose garments of different

lengths, and increase or diminish the number of them, according to the

frequent and sudden changes of their weather; hence they have very few

acute diseases among them. Those inhabitants of Pennsylvania who have

acquired the arts of conforming to the changes and extremes of our

weather in dress, diet, and manners, escape most of those acute diseases

which are occasioned by the sensible qualities of the air; and faithful

inquiries and observations have proved, that they attain to as great

ages as the same number of people in any part of the world.

[36] Observations on the Air and Epidemic Diseases, vol. I. p. 5.

AN ACCOUNT

OF THE

BILIOUS REMITTING FEVER,

AS IT APPEARED

_IN PHILADELPHIA_,

IN THE SUMMER AND AUTUMN OF THE YEAR 1780.

Before I proceed to describe this fever, it will be necessary to give

a short account of the weather, and of the diseases which preceded its

appearance.

The spring of 1780 was dry and cool. A catarrh appeared among children

between one year, and seven years of age. It was accompanied by a

defluxion from the eyes and nose, and by a cough and dyspn[oe]a,

resembling, in some instances, the cynanche trachealis, and in others

a peripneumony. In some cases it was complicated with the symptoms of

a bilious remitting, and intermitting fever. The exacerbations of this

fever were always attended with dyspn[oe]a and cough. A few patients

expectorated blood. Some had swellings behind their ears, and others

were affected with small ulcers in the throat. I met with only one case

of this fever in which the pulse indicated bleeding. The rest yielded

in a few days to emetics, blisters, and the bark, assisted by the usual

more simple remedies in such diseases.

An intermittent prevailed among adults in the month of May.

July and August were uncommonly warm. The mercury stood on the 6th of

August at 94-1/2°, on the 15th of the same month at 95°, and for several

days afterwards at 90°. Many labouring people perished during this month

by the heat, and by drinking, not only cold water, but cold liquors of

several kinds, while they were under the violent impressions of the heat.

The vomiting and purging prevailed universally, during these two warm

months, among the children, and with uncommon degrees of mortality.

Children from one year to eight and nine years old were likewise very

generally affected by blotches and little boils, especially in their

faces. An eruption on the skin, called by the common people the prickly

heat, was very common at this time among persons of all ages. The winds

during these months blew chiefly from the south, and south-west. Of

course they passed over the land which lies between the city, and the

conflux of the rivers Delaware and Schuylkill, the peculiar situation of

which, at that time, has been already described.

The dock, and the streets of Philadelphia, supplied the winds at this

season, likewise, with a portion of their unwholesome exhalations.

The muschetoes were uncommonly numerous during the autumn. A certain

sign (says Dr. Lind) of an unwholesome atmosphere.

The remitting fever made its first appearance in July and August, but

its symptoms were so mild, and its extent so confined, that it excited

no apprehensions of its subsequent more general prevalence throughout

the city.

On the 19th of August the air became suddenly very cool. Many hundred

people in the city complained, the next day, of different degrees of

indisposition, from a sense of lassitude, to a fever of the remitting

type. This was the signal of the epidemic. The weather continued cool

during the remaining part of the month, and during the whole month of

September. From the exposure of the district of Southwark (which is

often distinguished by the name of the _Hill_) to the south-west winds,

the fever made its first appearance in that appendage of the city.

Scarcely a family, and, in many families, scarcely a member of them,

escaped it. From the Hill it gradually travelled along the second street

from the Delaware, improperly called Front-street. For a while it was

confined to this street only, after it entered the city, and hence it

was called by some people the _Front-street fever_. It gradually spread

through other parts of the city, but with very different degrees of

violence. It prevailed but little in the Northern Liberties. It was

scarcely known beyond Fourth-street from the Delaware. Intemperance in

eating or drinking, riding in the sun or rain, watching, fatigue, or

even a fright, but more frequently cold, all served to excite the seeds

of this fever into action, where-ever they existed.

All ages and both sexes were affected by this fever. Seven of the

practitioners of physic were confined by it nearly at the same time. The

city, during the prevalence of the fever, was filled with an unusual

number of strangers, many of whom, particularly the Friends (whose

yearly meeting was held in the month of September), were affected by

it. No other febrile disease was observed during this time in the city.

This fever generally came on with rigour, but seldom with a regular

chilly fit, and often without any sensation of cold. In some persons it

was introduced by a slight sore throat, and in others by a hoarseness

which was mistaken for a common cold. A giddiness in the head was the

forerunner of the disease in some people. This giddiness attacked so

suddenly, as to produce, in several instances, a faintness, and even

symptoms of apoplexy. It was remarkable, that all those persons who were

affected in this violent manner, recovered in two or three days.

I met with one instance of this fever attacking with coma, and another

with convulsions, and with many instances, in which it was introduced by

a delirium.

The pains which accompanied this fever were exquisitely severe in the

head, back, and limbs. The pains in the head were sometimes in the back

parts of it, and at other times they occupied only the eyeballs. In some

people, the pains were so acute in their backs and hips, that they could

not lie in bed. In others, the pains affected the neck and arms, so as

to produce in one instance a difficulty of moving the fingers of the

right hand. They all complained more or less of a soreness in the seats

of these pains, particularly when they occupied the head and eyeballs. A

few complained of their flesh being sore to the touch, in every part of

the body. From these circumstances, the disease was sometimes believed

to be a rheumatism; but its more general name among all classes of

people was, the _break-bone fever_.

I met with one case of pain in the back, and another of an acute

ear-ach, both of which returned periodically every night, and without

any fever.

A nausea universally, and in some instances a vomiting, accompanied by a

disagreeable taste in the mouth, attended this fever. The bowels were,

in most cases, regular, except where the disease fell with its whole

force upon them, producing a dysentery.

The tongue was generally moist, and tinctured of a yellow colour.

The urine was high coloured, and in its usual quantity in fevers.

The skin was generally moist, especially where the disease terminated on

the third or fourth day.

The pulse was quick and full, but never hard, in a single patient that

came under my care, till the 28th of September.

It was remarkable, that little, and, in some instances, no thirst

attended this fever.

A screatus, or constant hawking and spitting, attended in many cases

through the whole disease, and was a favourable symptom.

There were generally remissions in this fever every morning, and

sometimes in the evening. The exacerbations were more severe every other

day, and two exacerbations were often observed in one day.

A rash often appeared on the third and fourth days, which proved

favourable. This rash was accompanied, in some cases, by a burning in

the palms of the hands and soles of the feet. Many people at this time,

who were not confined to their beds, and some, who had no fever, had an

efflorescence on their skins.

In several persons the force of the disease seemed to fall upon the

face, producing swellings under the jaw and in the ears, which in some

instances terminated in abscesses.

When the fever did not terminate on the third or fourth day, it

frequently ran on to the eleventh, fourteenth, and even twentieth days,

assuming in its progress, according to its duration, the usual symptoms

of the typhus gravior, or mitior, of Doctor Cullen. In some cases, the

discharge of a few spoons-full of blood from the nose accompanied a

solution of the fever on the third or fourth day; while in others, a

profuse hæmorrhage from the nose, mouth, and bowels, on the tenth and

eleventh days, preceded a fatal issue of the disease.

Several cases came under my care, in which the fever was succeeded by a

jaundice.

The disease terminated in some cases without sweating, or a sediment in

the urine; nor did I observe such patients more disposed to relapse than

others, provided they took a sufficient quantity of the bark.

About the beginning of October the weather became cool, accompanied

by rain and an easterly wind. This cool and wet weather continued

for four days. The mercury in the thermometer fell to 60°, and fires

became agreeable. From this time the fever evidently declined, or was

accompanied by inflammatory symptoms. On the 16th of October, I met

with a case of inflammatory angina; and on the next day I visited a

patient who had a complication of the bilious fever with a pleurisy, and

whose blood discovered strong marks of the presence of the inflammatory

diathesis. His stools were of a green and black colour. On the third

day of his disease a rash appeared on his skin, and on the fourth, in

consequence of a second bleeding, his fever terminated with the common

symptoms of a crisis.

During the latter end of October, and the first weeks in November, the

mercury in the thermometer fluctuated between 50° and 60°. Pleurisies

and inflammatory diseases of all kinds now made their appearance. They

were more numerous and more acute, than in this stage of the autumn, in

former years. I met with one case of pleurisy in November, which did not

yield to less than four plentiful bleedings.

I shall now add a short account of the METHOD I pursued in the treatment

of this fever.

I generally began by giving a gentle vomit of tartar emetic. This

medicine, if given while the fever was in its forming state, frequently

produced an immediate cure; and if given after its formation, on the

_first_ day, seldom failed of producing a crisis on the third or fourth

day. The vomit always discharged more or less bile. If a nausea, or

an ineffectual attempt to vomit continued after the exhibition of the

tartar emetic, I gave a second dose of it with the happiest effects.

If the vomit failed of opening the bowels, I gave gentle doses of salts

and cream of tartar[37], or of the butter-nut pill[38], so as to procure

two or three plentiful stools. The matter discharged from the bowels was

of a highly bilious nature. It was sometimes so acrid as to excoriate

the rectum, and so offensive, as to occasion, in some cases, sickness

and faintness both in the patients and in their attendants. In every

instance, the patients found relief by these evacuations, especially

from the pains in the head and limbs.

[37] I have found that cream of tartar renders the purging neutral

salts less disagreeable to the taste and stomach; but accident

has lately taught me, that the juice of two limes or of one

lemon, with about half an ounce of loaf sugar, added to six

drachms of Glauber or Epsom salt, in half a pint of boiling

water, form a mixture that is nearly as pleasant as strong

beverage.

[38] This pill is made from an extract of a strong decoction of the

bark of the white walnut-tree.

In those cases, where the prejudices of the patients against an emetic,

or where an advanced state of pregnancy, or a habitual predisposition

to a vomiting of blood occurred, I discharged the bile entirely by

means of the lenient purges that have been mentioned. In this practice

I had the example of Doctor Cleghorn, who prescribed purges with great

success in a fever of the same kind in Minorca, with that which has been

described[39]. Doctor Lining prescribed purges with equal success in an

autumnal pleurisy in South Carolina, which I take to have been a form

of a bilious remittent, accompanied by an inflammatory affection of the

breast.

[39] The tertiana interposita remissione tantum of Dr. Cullen.

After evacuating the contents of the stomach and bowels, I gave small

doses of tartar emetic, mixed with Glauber's salt. This medicine excited

a general perspiration. It likewise kept the bowels gently open, by

which means the bile was discharged as fast as it was accumulated.

I constantly recommended to my patients, in this stage of the disorder,

to _lie in bed_. This favoured the eruption of the rash, and the

solution of the disease by perspiration. Persons who struggled against

the fever by _sitting up_, or who attempted to shake it off by labour or

exercise, either sunk under it, or had a slow recovery.

A clergyman of a respectable character from the country, who was

attacked by the disease in the city, returned home, from a desire of

being attended by his own family, and died in a few days afterwards.

This is only one, of many cases, in which I have observed travelling,

even in the easiest carriages, to prove fatal in fevers after they were

formed, or after the first symptoms had shown themselves. The quickest

and most effectual way of conquering a fever, in most cases, is, by an

early submission to it.

The drinks I recommended to my patients were sage and balm teas, weak

punch, lemonade, wine whey, tamarind and apple water.

The apple water should be made by pouring boiling water upon slices of

raw apples. It is more lively than that which is made by pouring the

water on roasted apples.

I found obvious advantages, in many cases, from the use of pediluvia,

every night.

In every case, I found the patients refreshed and relieved by frequent

changes of their linen.

On the third or fourth day, in the forenoon, the pains in the head and

back generally abated, with a sweat which was diffused over the whole

body. The pulse at this time remained quick and weak. This was, however,

no objection to the use of the bark, a few doses of which immediately

abated its quickness, and prevented a return of the fever.

If the fever continued beyond the third or fourth day without an

intermission, I always had recourse to blisters. Those which were

applied to the neck, and behind the ears, produced the most immediate

good effects. They seldom failed of producing an intermission in the

fever, the day after they were applied. Where delirium or coma attended,

I applied the blister to the neck on the _first_ day of the disease. A

worthy family in this city will always ascribe the life of a promising

boy, of ten years old, to the early application of a blister to the

neck, in this fever.

Where the fever did not yield to blisters, and assumed malignant, or

typhus symptoms, I gave the medicines usually exhibited in both those

states of fever.

I took notice, in the history of this fever, that it was sometimes

accompanied with symptoms of a dysentery. Where this disease appeared,

I prescribed lenient purges and opiates. Where these failed of success,

I gave the bark in the intermissions of the pain in the bowels, and

applied blisters to the wrists. The good effects of these remedies led

me to conclude, that the dysentery was the febris introversa of Dr.

Sydenham.

I am happy in having an opportunity, in this place, of bearing a

testimony in favour of the usefulness of OPIUM in this disease, after

the necessary evacuations had been made. I yielded, in prescribing it

at first, to the earnest solicitations of my patients for something to

give them relief from their insupportable pains, particularly when they

were seated in the eyeballs and head. Its salutary effects in procuring

sweat, and a remission of the fever, led me to prescribe it afterwards

in almost every case, and always with the happiest effects. Those

physicians enjoy but little pleasure in practising physic, who know not

how much of the pain and anguish of fevers, of a certain kind, may be

lessened by the judicious use of opium.

In treating of the remedies used in this disease, I have taken no notice

of blood-letting. Out of several hundred patients whom I visited in this

fever, I did not meet with a single case, before the 27th of September,

in which the state of the pulse indicated this evacuation. It is true,

the pulse was _full_, but never _hard_. I acknowledge that I was called

to several patients who had been bled without the advice of a physician,

who recovered afterwards on the usual days of the solution of the fever.

This only can be ascribed to that disposition which Doctor Cleghorn

attributes to fevers, to preserve their types under every variety of

treatment, as well as constitution. But I am bound to declare further,

that I heard of several cases in which bleeding was followed by a fatal

termination of the disease.

In this fever relapses were very frequent, from exposure to the rain,

sun, or night air, and from an excess in eating or drinking.

The convalescence from this disease was marked by a number of

extraordinary symptoms, which rendered patients the subjects of medical

attention for many days after the pulse became perfectly regular, and

after the crisis of the disease.

A bitter taste in the mouth, accompanied by a yellow colour on the

tongue, continued for near a week.

Most of those who recovered complained of nausea, and a total want of

appetite. A faintness, especially upon sitting up in bed, or in a chair,

followed this fever. A weakness in the knees was universal. I met with

two patients, who were most sensible of this weakness in the right knee.

An inflammation in one eye, and in some instances in both eyes, occurred

in several patients after their recovery.

But the most remarkable symptom of the convalescence from this fever,

was an uncommon dejection of the spirits. I attended two young ladies,

who shed tears while they vented their complaints of their sickness

and weakness. One of them very aptly proposed to me to change the name

of the disease, and to call it, in its present stage, instead of the

break-bone, the _break-heart fever_.

To remove these symptoms, I gave the tincture of bark and elixir of

vitriol in frequent doses. I likewise recommended the plentiful use of

ripe fruits; but I saw the best effects from temperate meals of oysters,

and a liberal use of porter. To these was added, gentle exercise in the

open air, which gradually completed the cure.

AN ACCOUNT

OF THE

_SCARLATINA ANGINOSA_,

AS IT

APPEARED IN PHILADELPHIA,

IN THE YEARS 1783 AND 1784.

The beginning of the month of July was unusually cool; insomuch that

the mercury in Fahrenheit's thermometer stood at 61° in the day time,

and fires were very comfortable, especially in the evening. In the last

week but one of this month, the weather suddenly became so warm, that

the mercury rose to 94-1/2°, at which it remained for three days. As

this heat was accompanied by no breeze from any quarter, the sense of

it was extremely distressing to many people. Upwards of twenty persons

died in the course of those three days, from the excess of the heat,

and from drinking cold water. Three old people died suddenly within

this space of time. This extreme heat was succeeded by cool weather,

the mercury having fallen to 60°, and the month closed with producing

a few intermitting and remitting fevers, together with several cases of

inflammatory angina.

The weather in the month of August was extremely variable. The mercury,

after standing for several days at 92°, suddenly fell so low, as not

only to render fires necessary, but in many places to produce frost.

Every form of fever made its appearance in this month. The synocha was

so acute, in several cases, as to require from three to four bleedings.

The remitting fever was accompanied by an uncommon degree of nausea

and faintness. Several people died, after a few days' illness, of

the malignant bilious fever, or typhus gravior, of Dr. Cullen. The

intermittents had nothing peculiar in them, in their symptoms or method

of cure.

Towards the close of the month, the scarlatina anginosa made its

appearance, chiefly among children.

The month of September was cool and dry, and the scarlatina anginosa

became epidemic among adults as well as young people. In most of the

patients who were affected by it, it came on with a chilliness and a

sickness at the stomach, or a vomiting; which last was so invariably

present, that it was with me a pathognomonic sign of the disease. The

matter discharged from the stomach was always bile. The swelling of

the throat was in some instances so great, as to produce a difficulty

of speaking, swallowing, and breathing. In a few instances, the speech

was accompanied by a squeaking voice, resembling that which attends the

cynanche trachealis. The ulcers on the tonsils were deep, and covered

with white, and, in some instances, with black sloughs. In several

cases, there was a discharge of a thick mucus from the nose, from the

beginning, but it oftener occurred in the decline of the disease, which

most frequently happened on the fifth day. Sometimes the subsiding of

the swelling of the throat was followed by a swelling behind the ears.

An eruption on the skin generally attended the symptoms which have been

described. But this symptom appeared with considerable variety. In some

people it preceded, and in others it followed the ulcers and swelling of

the throat. In some, it appeared only on the outside of the throat, and

on the breast; in others, it appeared chiefly on the limbs. In a few it

appeared on the second or third day of the disease, and never returned

afterwards. I saw two cases of eruption without a single symptom of

sore throat. The face of one of those patients was swelled, as in the

erisypelas. In the other, a young girl of seven years old, there was

only a slight redness on the skin. She was seized with a vomiting, and

died delirious in fifty-four hours. Soon after her death, a livid colour

appeared on the outside of her throat.

The bowels, in this degree of the disease, were in general regular. I

can recollect but few cases which were attended by a diarrh[oe]a.

The fever which accompanied the disease was generally the typhus mitior

of Doctor Cullen. In a few cases it assumed symptoms of great malignity.

The disease frequently went off with a swelling of the hands and feet.

I saw one instance in a gentlewoman, in whom this swelling was absent,

who complained of very acute pains in her limbs, resembling those of the

rheumatism.

In two cases which terminated fatally, there were large abscesses; the

one on the outside, and the other on the inside of the throat. The first

of these cases was accompanied by troublesome sores on the ends of the

fingers. One of these patients lived twenty-eight, and the other above

thirty days, and both appeared to die from the discharge which followed

the opening of their abscesses.

Between the degrees of the disease which I have described, there were

many intermediate degrees of indisposition which belonged to this

disease.

I saw in several cases a discharge from behind the ears, and from the

nose, with a slight eruption, and no sore throat. All these patients

were able to sit up, and walk about.

I saw one instance of a discharge from the inside of one of the ears in

a child, who had ulcers in his throat, and the squeaking voice.

In some, a pain in the jaw, with swellings behind the ears, and a slight

fever, constituted the whole of the disease.

In one case, the disease came on with a coma, and in several patients it

went off with this symptom.

A few instances occurred of adults, who walked about, and even

transacted business, until a few hours before they died.

The intermitting fever, which made its appearance in August, was not

lost during the month of September. It continued to prevail, but with

several peculiar symptoms. In many persons it was accompanied by an

eruption on the skin, and a swelling of the hands and feet. In some,

it was attended by a sore throat and pains behind the ears. Indeed,

such was the predominance of the scarlatina anginosa, that many

hundred people complained of sore throats, without any other symptom

of indisposition. The slightest occasional or exciting cause, and

particularly cold, seldom failed of producing the disease.

The month of October was much cooler than September, and the disease

continued, but with less alarming symptoms. In several adults, who were

seized with it, the hardness of the pulse indicated blood-letting. The

blood, in one case, was covered with a buffy coat, but beneath its

surface it was dissolved.

In the month of November, the disease assumed several inflammatory

symptoms, and was attended with much less danger than formerly. I

visited one patient whose symptoms were so inflammatory as to require

two bleedings. During the decline of the disease, many people complained

of troublesome sores on the ends of their fingers. A number of children

likewise had sore throats and fevers, with eruptions on their skins,

which resembled the chicken-pox. I am disposed to suspect that this

eruption was the effect of a spice of the scarlatina anginosa, as

several instances occurred of patients who had all the symptoms of this

disease, in whom an eruption of white blisters succeeded their recovery.

This form of the disease has been called by Sauvage, the scarlatina

variolosa.

I saw one case of sore throat, which was succeeded not only by swellings

in the abdomen and limbs, but by a catarrh, which brought on a fatal

consumption.

A considerable shock of an earthquake was felt on the 29th of this

month, at ten o'clock at night, in the city of Philadelphia; but no

change was perceived in the disease, in consequence of it.

In December, January, and February, the weather was intensely cold.

There was a thaw for a few days in January, which broke the ice of the

Delaware, but it was followed by cold so excessive, as to close the

river till the beginning of March. The mercury, on the 28th and 29th of

February, stood below 0 in Fahrenheit's thermometer.

For a few weeks in the beginning of December, the disease disappeared

in the circle of my patients, but it broke out with great violence the

latter end of that month, and in the January following. Some of the

worst cases that I met with (three of which proved fatal) were in those

two months.

The disease disappeared in the spring, but it spread afterwards through

the neighbouring states of New-Jersey, Delaware, and Maryland.

I shall now add an account of the remedies which I administered in this

disease.

In every case that I was called to, I began the cure by giving a vomit

joined with calomel. The vomit was either tartar emetic or ipecacuanha,

according to the prejudices, habits, or constitutions of my patients.

A quantity of bile was generally discharged by this medicine. Besides

evacuating the contents of the stomach, it cleansed the throat in its

passage downwards. To ensure this effect from the calomel, I always

directed it to be given mixed with syrup or sugar and water, so as to

diffuse it generally over every part of the throat. The calomel seldom

failed to produce two or three stools. In several cases I was obliged,

by the continuance of nausea, to repeat the emetics, and always with

immediate and obvious advantage. I gave the calomel in moderate doses

in every stage of the disease. To restrain its purgative effects, when

necessary, I added to it a small quantity of opium.

During the whole course of the disease, where the calomel failed of

opening the bowels, I gave lenient purges, when a disposition to

costiveness required them.

The throat was kept clean by detergent gargles. In several instances

I saw evident advantages from adding a few grains of calomel to them.

In cases of great difficulty of swallowing or breathing, the patients

found relief from receiving the steams of warm water mixed with a little

vinegar, through a funnel into the throat.

A perspiration kept up by gentle doses of antimonials, and diluting

drinks, impregnated with wine, always gave relief.

In every case which did not yield to the above remedies on the third

day, I applied a blister behind each ear, or one to the neck, and, I

think, always with good effects.

I met with no cases in which the bark appeared to be indicated, except

the three in which the disease proved fatal. Where the sore throat was

blended with the intermitting fever, the bark was given with advantage.

But in common cases it was unnecessary. Subsequent observations have led

me to believe, with Doctor Withering, that it is sometimes hurtful in

this disease.

It proved fatal in many parts of the country, upon its first appearance;

but wherever the mode of treatment here delivered was adopted, its

mortality was soon checked. The calomel was used very generally in

New-Jersey and New-York. In the Delaware state, a physician of character

made it a practice not only to give calomel, but to anoint the outside

of the throat with mercurial ointment.

ADDITIONAL OBSERVATIONS

UPON THE

_Scarlatina Anginosa_.

This disease has prevailed in Philadelphia, at different seasons,

ever since the year 1783. It has blended itself occasionally with all

our epidemics. Many cases have come under my notice since its first

appearance, in which dropsical swellings have succeeded the fever. In

some instances there appeared to be effusions of water not only in the

limbs and abdomen, but in the thorax. They yielded, in every case that

I attended, to purges of calomel and jalap. Where these swellings were

neglected, they sometimes proved fatal.

In the winter of 1786-7, the scarlatina anginosa was blended with the

cynanche parotidea, and in one instance with a typhus mitior. The

last was in a young girl of nine years of age. She was seized with a

vomiting of bile and an efflorescence on her breast, but discovered no

other symptoms of the scarlatina anginosa till the sixteenth day of her

fever, when a swelling appeared on the outside of her throat, and after

her recovery, a pain and swelling in one of her knees.

In the month of July, 1787, a number of people were affected by sudden

swellings of their lips and eyelids. These swellings generally came on

in the night, were attended with little or no pain, and went off in two

or three days. I met with only one case in which there was a different

issue to these symptoms. It was in a patient in the Pennsylvania

hospital, in whom a swelling in the lips ended in a suppuration, which,

notwithstanding the liberal use of bark and wine, proved fatal in the

course of twelve days.

In the months of June and July, 1788, a number of people were affected

by sudden swellings, not only of the lips, but of the cheeks and throat.

At the same time many persons were affected by an inflammation of the

eyes. The swellings were attended with more pain than they were the year

before, and some of them required one or two purges to remove them; but

in general they went without medicine, in two or three days.

Is it proper to refer these complaints to the same cause which produces

the scarlatina anginosa?

The prevalence of the scarlatina anginosa at the _same time_ in this

city; its disposition to produce swellings in different parts of the

body; and the analogy of the intermitting fever, which often conceals

itself under symptoms that are foreign to its usual type; all seem to

render this conjecture probable. In one of the cases of an inflammation

of the eye, which came under my notice, the patient was affected by a

vomiting a few hours before the inflammation appeared, and complained

of a sickness at his stomach for two or three days afterwards. Now

a vomiting and nausea appear to be very generally symptoms of the

scarlatina anginosa.

In the autumn of 1788, the scarlatina anginosa appeared with different

degrees of violence in many parts of the city. In two instances it

appeared with an obstinate diarrh[oe]a; but it was in young subjects,

and not in adults, as described by Doctor Withering. In both cases, the

disease proved fatal; the one on the third, the other on the fifth day.

In the month of December of the same year, I saw one case in which a

running from one of the ears, and a deafness came on, on the fifth day,

immediately after the discharge of mucus from the nose had ceased. This

case terminated favourably on the ninth day, but was succeeded, for

several days afterwards, by a troublesome cough.

I shall conclude this essay by the following remarks:

1. Camphor has often been suspended in a bag from the neck, as a

preservative against this disease. Repeated observations have taught

me, that it possesses little or no efficacy for this purpose. I have

had reason to entertain a more favourable opinion of the benefit of

washing the hands and face with vinegar, and of rinsing the mouth and

throat with vinegar and water every morning, as means of preventing this

disease.

2. Whenever I have been called to a patient where the scarlatina

appeared to be in a _forming_ state, a vomit of ipecacuanha or tartar

emetic, mixed with a few grains of calomel, has never failed of

completely checking the disease, or of so far mitigating its violence,

as to dispose it to a favourable issue in a few days; and if these

observations should serve no other purpose than to awaken the early

attention of patients and physicians to this speedy and effectual

remedy, they will not have been recorded in vain.

3. When the matter which produces this disease has been received into

the body, a purge has prevented its being excited into action, or

rendered it mild, throughout a whole family. For this practice I am

indebted to some observations on the scarlatina, published by Dr. Sims

in the first volume of the Medical Memoirs.

4. During the prevalence of the inflammatory constitution of the

atmosphere, between the years 1793 and 1800, this disease occurred

occasionally in Philadelphia, and yielded, like the other epidemics of

those years, to copious blood-letting, and other depleting remedies.

AN INQUIRY

INTO

THE CAUSE AND CURE

OF

_THE CHOLERA INFANTUM_.

By this name I mean to designate a disease, called, in Philadelphia,

the "vomiting and purging of children." From the regularity of its

appearance in the summer months, it is likewise known by the name of

"the disease of the season." It prevails in most of the large towns of

the United States. It is distinguished in Charleston, in South Carolina,

by the name of "the April and May disease," from making its first

appearance in those two months. It seldom appears in Philadelphia till

the middle of June, or the beginning of July, and generally continues

till near the middle of September. Its frequency and danger are always

in proportion to the heat of the weather. It affects children from the

first or second week after their birth, till they are two years old. It

sometimes begins with a diarrh[oe]a, which continues for several days

without any other symptom of indisposition; but it more frequently comes

on with a violent vomiting and purging, and a high fever. The matter

discharged from the stomach and bowels is generally yellow or green,

but the stools are sometimes slimy and bloody, without any tincture

of bile. In some instances they are nearly as limpid as water. Worms

are frequently discharged in each kind of the stools that has been

described. The children, in this stage of the disease, appear to suffer

a good deal of pain. They draw up their feet, and are never easy in one

posture. The pulse is quick and weak. The head is unusually warm, while

the extremities retain their natural heat, or incline to be cold. The

fever is of the remitting kind, and discovers evident exacerbations,

especially in the evenings. The disease affects the head so much, as in

some instances to produce symptoms not only of delirium, but of mania,

insomuch that the children throw their heads backwards and forwards, and

sometimes make attempts to scratch, and to bite their parents, nurses,

and even themselves. A swelling frequently occurs in the abdomen, and

in the face and limbs. An intense thirst attends every stage of the

disease. The eyes appear languid and hollow, and the children generally

sleep with them half closed. Such is the insensibility of the system in

some instances in this disease, that flies have been seen to alight upon

the eyes when open, without exciting a motion in the eyelids to remove

them. Sometimes the vomiting continues without the purging, but more

generally the purging continues without the vomiting, through the whole

course of the disease. The stools are frequently large, and extremely

f[oe]tid, but in some instances they are without smell, and resemble

drinks and aliment which have been taken into the body. The disease is

sometimes fatal in a few days. I once saw it carry off a child in four

and twenty hours. Its duration is varied by the season of the year, and

by the changes in the temperature of the weather. A cool day frequently

abates its violence, and disposes it to a favourable termination. It

often continues, with occasional variations in its appearance, for six

weeks or two months. Where the disease has been of long continuance, the

approach of death is gradual, and attended by a number of distressing

symptoms. An emaciation of the body to such a degree, as that the

bones come through the skin, livid spots, a singultus, convulsions, a

strongly marked hippocratic countenance, and a sore mouth, generally

precede the fatal termination of this disease. Few children ever

recover, after the last symptoms which have been mentioned make their

appearance.

This disease has been ascribed to several causes; of each of which I

shall take notice in order.

I. It has been attributed to dentition. To refute this opinion, it will

be necessary to observe, that it appears only in one season of the year.

Dentition, I acknowledge, sometimes aggravates it; hence we find it is

most severe in that period of life, when the greatest number of teeth

make their appearance, which is generally about the 10th month. I think

I have observed more children to die of this disease at that age, than

at any other.

II. Worms have likewise been suspected of being the cause of this

disease. To this opinion, I object the uncertainty of worms ever

producing an idiopathic fever, and the improbability of their combining

in such a manner as to produce an annual epidemic disease of any kind.

But further, we often see the disease in all its force, before that age,

in which worms usually produce diseases; we likewise often see it resist

the most powerful anthelmintic medicines; and, lastly, it appears

from dissection, where the disease has proved fatal, that not a single

worm has been discovered in the bowels. It is true, worms are in some

instances discharged in this disease, but they are frequently discharged

in greater numbers in the hydrocephalus internus, and in the small-pox,

and yet who will assert either of those diseases to be produced by worms.

III. The summer fruits have been accused of producing this disease. To

this opinion I object, that the disease is but little known in country

places, where children eat much more fruit than in cities. As far as I

have observed, I am disposed to believe, that the moderate use of ripe

fruits, rather tends to prevent, than to induce the disease.

From the discharge of bile which generally introduces the disease,

from the remissions and exacerbations of the fever which accompanies

it, and from its occurring nearly in the same season with the cholera

and remitting fever in adults, I am disposed to consider it as a

modification of the same diseases. Its appearance earlier in the season

than the cholera and remitting fever in adults, must be ascribed to the

constitutions of children being more predisposed from weakness to be

acted upon, by the remote causes which produce those diseases.

I shall now mention the remedies which are proper and useful in this

disease.

I. The first indication of cure is to evacuate the bile from the stomach

and bowels. This should be done by gentle doses of ipecacuanha, or

tartar emetic. The vomits should be repeated occasionally, if indicated,

in every stage of the disease. The bowels should be opened by means

of calomel, manna, castor oil, or magnesia. I have generally found

rhubarb improper for this purpose, while the stomach was in a very

irritable state. In those cases, where there is reason to believe that

the offending contents of the primæ viæ have been discharged by nature

(which is often the case), the emetics and purges should by no means be

given; but, instead of them, recourse must be had to

II. Opiates. A few drops of liquid laudanum, combined in a testaceous

julep, with peppermint or cinnamon-water, seldom fail of composing the

stomach and bowels. In some instances, this medicine alone subdues

the disease in two or three days; but where it does not prove so

successful, it produces a remission of pain, and of other distressing

symptoms, in every stage of the disease.

III. Demulcent and diluting drinks have an agreeable effect in this

disease. Mint and mallow teas, or a tea made of blackberry roots infused

in cold water, together with a decoction of the shavings of hartshorn

and gum arabic with cinnamon, should all be given in their turns for

this purpose.

IV. Glysters made of flaxseed tea, or of mutton broth, or of starch

dissolved in water, with a few drops of liquid laudanum in them, give

ease, and produce other useful effects.

V. Plasters of Venice treacle applied to the region of the stomach,

and flannels dipped in infusions of bitter and aromatic herbs in warm

spirits, or Madeira wine, and applied to the region of the abdomen,

often afford considerable relief.

VI. As soon as the more violent symptoms of the disease are composed,

tonic and cordial medicines should be given. The bark in decoction,

or in substance (where it can be retained in that form), mixed with

a little nutmeg, often produces the most salutary effects. Port wine

or claret mixed with water are likewise proper in this stage of the

disease. After the disease has continued for some time, we often see

an appetite suddenly awakened for articles of diet of a stimulating

nature. I have seen many children recover from being gratified in an

inclination to eat salted fish, and the different kinds of salted meat.

In some instances they discover an appetite for butter, and the richest

gravies of roasted meats, and eat them with obvious relief to all their

symptoms. I once saw a child of sixteen months old, perfectly restored,

from the lowest stage of this disease, by eating large quantities of

rancid English cheese, and drinking two or three glasses of port wine

every day. She would in no instance eat bread with the cheese, nor taste

the wine, if it was mixed with water.

We sometimes see relief given by the use of the warm bath, in cases

of obstinate pain. The bath is more effectual, if warm wine is used,

instead of water.

I have had but few opportunities of trying the effects of cold water

applied to the body in this disease; but from the benefit which

attended its use in the cases in which it was prescribed, I am disposed

to believe that it would do great service, could we overcome the

prejudices which subsist in the minds of parents against it.

After all that has been said in favour of the remedies that have been

mentioned, I am sorry to add, that I have very often seen them all

administered without effect. My principal dependence, therefore, for

many years, has been placed upon

VII. Country air. Out of many hundred children whom I have sent into the

country, in every stage of this disease, I have lost but three; two of

whom were sent, contrary to my advice, into that unhealthy part of the

neighbourhood of Philadelphia called the _Neck_, which lies between the

city and the conflux of the rivers Delaware and Schuylkill. I have seen

one cure performed by this remedy, after convulsions had taken place.

To derive the utmost benefit from the country air, children should be

carried out on horseback, or in a carriage, every day; and they should

be exposed to the open air as much as possible in fair weather, in the

day time. Where the convenience of the constant benefit of country air

cannot be obtained, I have seen evident advantages from taking children

out of the city once or twice a day. It is extremely agreeable to see

the little sufferers revive as soon as they escape from the city air,

and inspire the pure air of the country.

I shall conclude this inquiry, by recommending the following methods of

preventing this disease, all of which have been found by experience to

be useful.

1. The daily use of the cold bath.

2. A faithful and attentive accommodation of the dresses of children, to

the state and changes of the air.

3. A moderate quantity of salted meat taken occasionally in those months

in which this disease usually prevails. It is perhaps in part from the

daily use of salted meat in diet, that the children of country people

escape this disease.

4. The use of sound old wine in the summer months. From a

tea-spoon-full, to half a wine glass full, according to the age of the

child, may be given every day. It is remarkable, that the children of

persons in easy circumstances, who sip occasionally with their parents

the remains of a glass of wine after dinner, are much less subject to

this disease, than the children of poor people, who are without the

benefit of that article of diet.

5. Cleanliness, both with respect to the skin and clothing of children.

Perhaps the neglect of this direction may be another reason why the

children of the poor, are most subject to this disease.

6. The removal of children into the country before the approach of warm

weather. This advice is peculiarly necessary during the whole period of

dentition. I have never known but one instance of a child being affected

by this disease, who had been carried into the country in order to avoid

it.

I have only to add to the above observations, that since the prevalence

of the yellow fever in Philadelphia after the year 1793, the cholera

infantum has assumed symptoms of such malignity, as to require bleeding

to cure it. In some cases, two and three bleedings were necessary for

that purpose.

OBSERVATIONS

ON THE

_CYNANCHE TRACHEALIS_.

The vulgar name of this disease in Pennsylvania is HIVES. It is a

corruption of the word _heaves_, which took its rise from the manner in

which the lungs heave in breathing. The worst degree of the disease is

called the BOWEL HIVES, from the great motion of the abdominal muscles

in respiration.

It has been called suffocatio stridula by Dr. Home, and cynanche

trachealis by Dr. Cullen. Professor Frank calls it trachitis, and Dr.

Darwin considers it as a pleurisy of the windpipe. By the two latter

names, the authors mean to convey the correct idea, that the disease is

the same in its nature with the common diseases of other internal parts

of the body.

It is brought on by the same causes which induce fever, particularly

by cold. I have seen it accompany, as well as succeed, the small-pox,

measles, scarlet-fever, and apthous sore throat. In the late Dr. Foulke

it succeeded acute rheumatism. The late Dr. Sayre informed me, he had

seen it occur in a case of yellow fever, in the year 1798.

It sometimes comes on suddenly, but it more frequently creeps on in the

form of a common cold. Its symptoms are sometimes constant, but they

more generally remit, particularly during the day. It attacks children

of all ages, from three months to five years old. But it occasionally

attacks adults. It generally runs its course in three or four days, but

we now and then see it protracted in a chronic and feeble form, for

eight and ten days.

Dissections show the following appearances in the trachea. 1. A slight

degree of inflammation. 2. A thick matter resembling mucus. 3. A

membrane similar to that which succeeds inflammation in the pleura and

bowels, formed from the coagulating lymph of the blood. 4. In some cases

the trachea exhibits no marks of disease of any kind. These cases are

generally violent, and terminate suddenly. The morbid excitement here

transcends inflammation. Similar instances of the absence of the common

signs of disease after death, occur in other parts of the body. Where

the cynanche trachealis has appeared in the high grade which has been

last mentioned, it has been called spasmodic. Where the serous vessels

of the trachea have been tinged with red blood, it has been considered

as inflammatory. Where a liquid matter has been found in the trachea,

it has been called humoral; and where a membrane has been seen adhering

to the trachea, it has received from Dr. Michaelis the name of angina

polyposa. But all these different issues of the cynanche trachealis are

the effects of a difference only in its force, or in its duration: they

all depend upon one remote, and one proximate cause.

In the _forming_ state of this disease, which may be easily known

by a hoarseness, and a slight degree of stertorous cough, a puke of

antimonial wine, tartar emetic, ipecacuanha, or oxymel of squills, is

for the most part an immediate cure. To be effectual, it should operate

four or five times. Happily children are seldom injured by a little

excess in the operation of this class of medicines. I have prevented the

formation of this disease many hundred times, and frequently in my own

family, by means of this remedy.

After the disease is completely formed, and appears with the usual

symptoms described by authors, the remedies should be

1. Blood-letting. The late Dr. Bailie of New-York used to bleed until

fainting was induced. His practice has been followed by Dr. Dick of

Alexandria, and with great success. I have generally preferred small,

but frequent, to copious bleedings. I once drew twelve ounces of blood,

at four bleedings, in one day, from a son of Mr. John Carrol, then in

the fourth year of his age. Dr. Physick bled a child, of but three

months old, three times in one day. Life was saved in both these cases.

Powerful as the lancet is, in this disease, its violence and danger

require that it should be aided by

2. Vomits. These should be given every day, or oftener, during the

continuance of the disease. Their good effects are much more obvious

and certain in a disease of the trachea, than of the lungs, and hence

their greater utility, as I shall say hereafter, in a consumption from a

catarrh, than from any other of its causes.

3. Purges. These should consist of calomel and jalap, or rhubarb, and

should always follow the use of emetics, if they fail of opening the

bowels.

4. Calomel should likewise be given in large doses. Dr. Physick gave

half a drachm of this medicine, in one day, to the infant whose case

has been mentioned. I have never known it excite a salivation when

given to children whose ages rendered them subjects of it, probably

because it has been given in such large quantities as to pass rapidly

through the bowels. Its good effects seem to depend upon its exciting a

counter-action in the whole intestinal canal, and thereby lessening the

disposition of the tracheal blood-vessels to discharge the mucus, or

form the membrane, which have been described.

5. Blisters should be applied to the throat, breast, neck, and even to

the limbs.

6. Dr. Archer of Maryland commends, in high terms, the use of polygola,

or Seneka snake-root, in this disease. I can say nothing in favour of

its exclusive use, from my own experience, having never given it, but as

an auxiliary to other remedies.

7. I have seen great relief given by the use of the warm bath,

especially when it has been followed by a gentle perspiration.

8. Towards the close of the disease, after the symptoms of great morbid

action begin to decline, a few drops of liquid laudanum, by quieting

the cough which generally succeeds it, often produce the most salutary

effects. They should be given in flaxseed, or bran, or onion tea, of

which drinks the patient should drink freely in every stage of the

disease.

The cynanche trachealis is attended with most danger, when the patient

labours under a _constant_ and audible stertorous breathing. The danger

is less, when a dry stertorous cough attends, with _easy_ respiration

in its intervals. The danger is nearly over, when the cough, though

stertorous, is _loose_, and accompanied with a _discharge_ of mucus from

the trachea.

An eruption of little red blotches, which frequently appears and

disappears two or three times in the course of this disease, is always a

favourable symptom.

I once attended a man from Virginia, of the name of Bampfield, who,

after an attack of this disease, was much distressed with the stertorous

breathing and cough which belong to it. I suspected both to arise from

a membrane formed by inflammation in his trachea. This membrane I

supposed to be in part detached from the trachea, from the rattling

noise which attended his breathing. He had used many remedies for it

to no purpose. I advised a salivation, which in less than three weeks

perfectly cured him.

Since the general adoption of the remedies which have been enumerated,

for the cynanche trachealis, instances of its mortality have become very

uncommon in the city of Philadelphia.

AN ACCOUNT

OF THE EFFICACY OF

BLISTERS AND BLEEDING,

IN THE CURE OF OBSTINATE

_Intermitting Fevers_.

The efficacy of these remedies will probably be disputed by every

regular-bred physician, who has not been a witness of their utility in

the above disease; but it becomes such physicians, before they decide

upon this subject, to remember, that many things are true in medicine,

as well as in other branches of philosophy, which are very improbable.

In all those cases of _autumnal_ intermittents, whether quotidian,

tertian, or quartan, in which the bark did not succeed after three or

four days trial, I have seldom found it fail after the application of

blisters to the wrists.

But in those cases where blisters had been neglected, or applied without

effect, and where the disease had been protracted into the _winter_

months, I have generally cured it by means of one or two moderate

bleedings.

The pulse in those cases is generally full, and sometimes a little hard,

and the blood when drawn for the most part appears sizy.

The bark is seldom necessary to prevent the return of the disease.

It is always ineffectual, where blood-letting is indicated. I have

known several instances where pounds of that medicine have been taken

without effect, in which the loss of ten or twelve ounces of blood has

immediately cured the disease.

I once intended to have added to this account of the efficacy of

blisters and bleeding in curing obstinate intermittents, testimonies

from a number of medical gentlemen, of the success with which they have

used them; but these vouchers have become so numerous, that they would

swell this essay far beyond the limits I wish to prescribe to it.

AN ACCOUNT

OF

THE DISEASE OCCASIONED

BY

_DRINKING COLD WATER_

IN WARM WEATHER,

AND THE METHOD OF CURING IT.

Few summers elapse in Philadelphia, in which there are not instances of

many persons being diseased by drinking cold water. In some seasons,

four or five persons have died suddenly from this cause, in one day.

This mortality falls chiefly upon the labouring part of the community,

who seek to allay their thirst by drinking the water from the pumps in

the streets, and who are too impatient, or too ignorant, to use the

necessary precautions for preventing its morbid or deadly effects upon

them. These accidents seldom happen, except when the mercury rises above

85° in Fahrenheit's thermometer.

Three circumstances generally concur to produce disease or death, from

drinking cold water. 1. The patient is extremely warm. 2. The water is

extremely cold. And 3. A large quantity of it is suddenly taken into the

body. The danger from drinking the cold water is always in proportion to

the degrees of combination which occur in the three circumstances that

have been mentioned.

The following symptoms generally follow, where cold water has been

taken, under the above circumstances, into the body:

In a few minutes after the patient has swallowed the water, he is

affected by a dimness of sight; he staggers in attempting to walk, and,

unless supported, falls to the ground; he breathes with difficulty; a

rattling is heard in his throat; his nostrils and cheeks expand and

contract in every act of respiration; his face appears suffused with

blood, and of a livid colour; his extremities become cold, and his pulse

imperceptible; and, unless relief be speedily obtained, the disease

terminates in death, in four or five minutes.

This description includes only the less common cases of the effects

of drinking a _large_ quantity of _cold_ water, when the body is

_preternaturally_ heated. More frequently, patients are seized with

acute spasms in the breast and stomach. These spasms are so painful as

to produce syncope, and even asphyxia. They are sometimes of the tonic,

but more frequently of the clonic kind. In the intervals of the spasms,

the patient appears to be perfectly well. The intervals between each

spasm become longer or shorter, according as the disease tends to life

or death.

It may not be improper to take notice, that punch, beer, and even toddy,

when drunken under the same circumstances as cold water, have all been

known to produce the same morbid and fatal effects.

I know of but one certain remedy for this disease, and that is LIQUID

LAUDANUM. The doses of it, as in other cases of spasm, should be

proportioned to the violence of the disease. From a tea-spoonful to near

a table-spoonful have been given in some instances, before relief has

been obtained. Where the powers of life appear to be suddenly suspended,

the same remedies should be used, which have been so successfully

employed in recovering persons supposed to be dead from drowning.

Care should be taken in every case of disease, or apparent death, from

drinking cold water, to prevent the patient's suffering from being

surrounded, or even attended by too many people.

Persons who have been recovered from the immediate danger which attends

this disease, are sometimes affected after it, by inflammations and

obstructions in the breast or liver. These generally yield to the usual

remedies which are administered in those complaints, when they arise

from other causes.

If neither the voice of reason, nor the fatal examples of those who

have perished from this cause, are sufficient to produce restraint

in drinking a _large_ quantity of _cold_ liquors, when the body is

_preternaturally_ heated, then let me advise to

1. Grasp the vessel out of which you are about to drink for a minute or

longer, with both your hands. This will abstract a portion of heat from

the body, and impart it at the same time to the cold liquor, provided

the vessel be made of metal, glass, or earth; for heat follows the same

laws, in many instances, in passing through bodies, with regard to its

relative velocity, which we observe to take place in electricity.

2. If you are not furnished with a cup, and are obliged to drink by

bringing your mouth in contact with the stream which issues from a

pump, or a spring, always wash your hands and face, previously to your

drinking, with a little of the cold water. By receiving the shock of

the water first upon those parts of the body, a portion of its heat is

conveyed away, and the vital parts are thereby defended from the action

of the cold.

By the use of these preventives, inculcated by advertisements pasted

upon pumps by the Humane Society, death from drinking cold water has

become a rare occurrence for many years past in Philadelphia.

AN ACCOUNT

OF THE

_EFFICACY OF COMMON SALT_,

IN THE CURE OF

HÆMOPTYSIS.

From the present established opinions and practice respecting the

cause and cure of hæmoptysis, the last medicine that would occur to a

regular-bred physician for the cure of it, is COMMON SALT; and yet I

have seen and heard of a great number of cases, in which it has been

administered with success.

The mode of giving it is to pour down from a tea to a table-spoonful

of clean fine salt, as soon as possible after the hæmorrhage begins

from the lungs. This quantity generally stops it; but the dose must

be repeated daily for three or four days, to prevent a return of the

disease. If the bleeding continue, the salt must be continued till it is

checked, but in larger doses. I have heard of several instances in which

two table spoons-full were taken at one time for several days.

It sometimes excites a sickness at the stomach, and never fails to

produce a burning sensation in the throat, in its passage into the

stomach, and considerable thirst afterwards.

I have found this remedy to succeed equally well in hæmorrhages, whether

they occurred in young or in old people, or with a weak or active pulse.

I had prescribed it for several years before I could satisfy myself with

a theory, to account for its extraordinary action upon the human body.

My inquiries led me to attend more particularly to the following facts:

1. Those persons who have been early instructed in vocal music, and who

use their vocal organs moderately through life, are seldom affected by a

hæmorrhage from the lungs.

2. Lawyers, players, public cryers, and city watchmen, all of whom

exercise their lungs either by long or loud speaking, are less affected

by this disease, than persons of other occupations.

I acknowledge I cannot extend this observation to the public teachers

of religion. I have known several instances of their being affected

by hæmoptysis; but never but one in which the disease came on in the

pulpit, and that was in a person who had been recently cured of it. The

cases which I have seen, have generally been brought on by catarrhs.

To this disease, the practice of some of our American preachers disposes

them in a peculiar manner; for it is very common with this class of

them, to expose themselves to the cold or evening air, immediately after

taking what a celebrated and eloquent preacher used to call a _pulpit

sweat_.

3. This hæmorrhage chiefly occurs in debilitated habits, or in persons

afflicted by such a predisposition to consumption, as indicates a weak

and relaxed state of the lungs.

4. It generally occurs when the lungs are in a passive state; as in

sitting, walking, and more frequently in lying. Many of the cases that I

have known, have occurred during _sleep_, in the middle of the night.

From these facts, is it not probable that the common salt, by acting

primarily and with great force upon the throat, extends its stimulus

to the bleeding vessel, and by giving it a tone, checks the further

effusion of blood?

I shall only add to this conjecture the following observations:

1. I have never known the common salt perform a cure, where the

hæmorrhage from the lungs has been a symptom of a confirmed consumption.

But even in this case it gives a certain temporary relief.

2. The exhibition of common salt in the hæmoptysis, should by no means

supersede the use of occasional bleeding when indicated by plethora,

nor of that diet which the state of the pulse, or of the stomach, may

require.

3. I have given the common salt in one case with success, in a

hæmorrhage from the stomach, accompanied by a vomiting; and have

heard of several cases in which it has been supposed to have checked

a discharge of blood from the nose and uterus, but I can say nothing

further in its favour in these last hæmorrhages, from my own experience.

It may perhaps serve to lessen the prejudices of physicians against

adopting improvements in medicine, that are not recommended by the

authority of colleges or universities, to add, that we are indebted to

an old woman, for the discovery of the efficacy of common salt in the

cure of hæmoptysis.

THOUGHTS

UPON

THE CAUSE AND CURE

OF THE

_PULMONARY CONSUMPTION_.

The ancient Jews used to say, that a man does not fulfil his duties in

life, who passes through it, without building a house, planting a tree,

and leaving a child behind him. A physician, in like manner, should

consider his obligations to his profession and society as undischarged,

who has not attempted to lessen the number of incurable diseases. This

is my apology for presuming to make the consumption the object of a

medical inquiry.

Perhaps I may suggest an idea, or fact, that may awaken the ideas and

facts which now lie useless in the memories or common-place books

of other physicians; or I may direct their attention to some useful

experiments upon this subject.

I shall begin my observations upon the consumption, by remarking,

1. That it is unknown among the Indians in North-America.

2. It is scarcely known by those citizens of the United States, who live

in the _first_ stage of civilized life, and who have lately obtained the

title of the _first settlers_.

The principal occupations of the Indian consist in war, fishing, and

hunting. Those of the first settler, are fishing, hunting, and the

laborious employments of subduing the earth, cutting down forests,

building a house and barn, and distant excursions, in all kinds of

weather, to mills and courts, all of which tend to excite and preserve

in the system, something like the Indian vigour of constitution.

3. It is less common in country places than in cities, and increases in

both, with intemperance and sedentary modes of life.

4. Ship and house carpenters, smiths, and all those artificers whose

business requires great exertions of strength in the _open_ air, in

_all_ seasons of the year, are less subject to this disease, than men

who work under cover, and at occupations which do not require the

constant action of their limbs.

5. Women, who sit more than men, and whose work is connected with less

exertion, are most subject to the consumption.

From these facts it would seem, that the most probable method of curing

the consumption, is to revive in the constitution, by means of exercise

or labour, that vigour which belongs to the Indians, or to mankind in

their first stage of civilization.

The efficacy of these means of curing consumption will appear, when we

inquire into the relative merit of the several remedies which have been

used by physicians in this disease.

I shall not produce among these remedies the numerous receipts for

syrups, boluses, electuaries, decoctions, infusions, pills, medicated

waters, powders, draughts, mixtures, and diet-drinks, which have so long

and so steadily been used in this disease; nor shall I mention as a

remedy, the best accommodated diet, submitted to with the most patient

self-denial; for not one of them all, without the aid of exercise, has

ever, I believe, cured a single consumption.

1. SEA-VOYAGES have cured consumptions; but it has been only when they

have been so long, or so frequent, as to substitute the long continuance

of gentle, to violent degrees of exercise of a shorter duration, or

where they have been accompanied by some degree of the labour and care

of navigating the ship.

2. A CHANGE OF CLIMATE has often been prescribed for the cure of

consumptions, but I do not recollect an instance of its having

succeeded, except when it has been accompanied by exercise, as in

travelling, or by some active laborious pursuit.

Doctor Gordon of Madeira, ascribes the inefficacy of the air of Madeira

in the consumption, in part to the difficulty patients find of using

exercise in carriages, or even on horseback, from the badness of the

roads in that island.

3. JOURNIES have often performed cures in the consumption, but it has

been chiefly when they have been long, and accompanied by difficulties

which have roused and invigorated the powers of the mind and body.

4. VOMITS and NAUSEATING MEDICINES have been much celebrated for the

cure of consumptions. These, by procuring a temporary determination to

the surface of the body, so far lessen the pain and cough, as to enable

patients to use profitable exercise. Where this has not accompanied or

succeeded the exhibition of vomits, I believe they have seldom afforded

any _permanent_ relief.

5. BLOOD-LETTING has often relieved consumptions; but it has been only

by removing the troublesome symptoms of inflammatory diathesis, and

thereby enabling the patients to use exercise, or labour, with advantage.

6. VEGETABLE BITTERS and some of the STIMULATING GUMS have in some

instances afforded relief in consumptions; but they have done so only

in those cases where there was great debility, accompanied by a total

absence of inflammatory diathesis. They have most probably acted by

their tonic qualities, as substitutes for labour and exercise.

7. A PLENTIFUL and REGULAR PERSPIRATION, excited by means of a flannel

shirt, worn next to the skin, or by means of a stove-room, or by a warm

climate, has in many instances _prolonged_ life in consumptive habits;

but all these remedies have acted as palliatives only, and thereby have

enabled the consumptive patients to enjoy the more beneficial effects of

exercise.

8. BLISTERS, SETONS, and ISSUES, by determining the perspirable matter

from the lungs to the surface of the body, lessen pain and cough, and

thereby prepare the system for the more salutary effects of exercise.

9. The effects of SWINGING upon the pulse and respiration, leave us no

room to doubt of its being a tonic remedy, and therefore a safe and

agreeable substitute for exercise.

From all these facts it is evident, that the remedies for consumptions

must be sought for in those _exercises and employments which give the

greatest vigour to the constitution_. And here I am happy in being able

to produce several facts which demonstrate the safety and certainty of

this method of cure.

During the late war, I saw three instances of persons in confirmed

consumptions, who were perfectly cured by the hardships of a military

life. They had been my patients previously to their entering into

the army. Besides these, I have heard of four well-attested cases of

similar recoveries from nearly the same remedies. One of these was

the son of a farmer in New-Jersey, who was sent to sea as the last

resource for a consumption. Soon after he left the American shore, he

was taken by a British cruiser, and compelled to share in all the duties

and hardships of a common sailor. After serving in this capacity for

twenty-two months, he made his escape, and landed at Boston, from whence

he travelled on foot to his father's house (nearly four hundred miles),

where he arrived in perfect health.

Doctor Way of Wilmington informed me, that a certain Abner Cloud, who

was reduced so low by a pulmonary consumption as to be beyond all relief

from medicine, was so much relieved by sleeping in the open air, and

by the usual toils of building a hut, and improving a farm, in the

unsettled parts of a new country in Pennsylvania, that he thought him in

a fair way of a perfect recovery.

Doctor Latimer of Wilmington had been long afflicted with a cough and an

occasional hæmoptysis. He entered into the American army as a surgeon,

and served in that capacity till near the end of the war; during which

time he was perfectly free from all pulmonary disease. The spitting of

blood returned soon after he settled in private practice. To remedy this

complaint, he had recourse to a low diet, but finding it ineffectual, he

partook liberally of the usual diet of healthy men, and he now enjoys a

perfect exemption from it.

It would be very easy to add many other cases, in which labour, the

employments of agriculture, and a life of hardship by sea and land, have

prevented, relieved, or cured, not only the consumption, but pulmonary

diseases of all kinds.

To the cases that have been mentioned, I shall add only one more,

which was communicated to me by the venerable Doctor Franklin, whose

conversation at all times conveyed instruction, and not less in

medicine than upon other subjects. In travelling, many years ago,

through New-England, the doctor overtook the post-rider; and after

some inquiries into the history of his life, he informed him that he

was bred a shoe-maker; that his confinement, and other circumstances,

had brought on a consumption, for which he was ordered by a physician

to ride on horseback. Finding this mode of exercise too expensive, he

made interest, upon the death of an old post-rider, to succeed to his

appointment, in which he perfectly recovered his health in two years.

After this he returned to his old trade, upon which his consumption

returned. He again mounted his horse, and rode post in all seasons and

weathers, between New-York and Connecticut river (about 140 miles), in

which employment he continued upwards of thirty years, in perfect health.

These facts, I hope, are sufficient to establish the advantages of

restoring the original vigour of the constitution, in every attempt to

effect a radical cure of consumption.

But how shall these remedies be applied in the time of peace, or in a

country where the want of woods, and brooks without bridges, forbid the

attainment of the laborious pleasures of the Indian mode of hunting;

or where the universal extent of civilization does not admit of our

advising the toils of a new settlement, and improvements upon bare

creation? Under these circumstances, I conceive substitutes may be

obtained for each of them, nearly of equal efficacy, and attainable with

much less trouble.

1. Doctor Sydenham pronounced riding on horseback, to be as certain a

cure for consumptions as bark is for an intermitting fever. I have no

more doubt of the truth of this assertion, than I have that inflammatory

fevers are now less frequent in London than they were in the time of

Doctor Sydenham. If riding on horseback in consumptions has ceased to be

a remedy in Britain, the fault is in the patient, and not in the remedy.

"It is a sign that the stomach requires milk (says Doctor Cadogan), when

it cannot bear it." In like manner, the inability of the patient to

bear this manly and wholesome exercise, serves only to demonstrate the

necessity and advantages of it. I suspect the same objections to this

exercise which have been made in Britain, will not occur in the United

States of America; for the Americans, with respect to the symptoms and

degrees of epidemic and chronic diseases, appear to be nearly in the

same state that the inhabitants of England were in the seventeenth

century. We find, in proportion to the decline of the vigour of the

body, that many occasional causes produce fever and inflammation, which

would not have done it a hundred years ago.

2. The laborious employments of agriculture, if steadily pursued, and

accompanied at the same time by the simple, but wholesome diet of a

farmhouse, and a hard bed, would probably afford a good substitute for

the toils of a savage or military life.

3. Such occupations or professions as require constant labour or

exercise in the open air, in all kinds of weather, may easily be

chosen for a young man who, either from hereditary predisposition, or

an accidental affection of the lungs, is in danger of falling into a

consumption. In this we should imitate the advice given by some wise

men, always to prefer those professions for our sons, which are the

least favourable to the corrupt inclinations of their hearts. For

example, where an undue passion for money, or a crafty disposition,

discover themselves in early life, we are directed to oppose them by

the less profitable and more disinterested professions of divinity or

physic, rather than cherish them by trade, or the practice of the law.

Agreeably to this analogy, weakly children should be trained to the

laborious, and the robust, to the sedentary occupations. From a neglect

of this practice, many hundred apprentices to taylors, shoemakers,

conveyancers, watchmakers, silversmiths, and mantua-makers, perish every

year by consumptions.

4. There is a case recorded by Dr. Smollet, of the efficacy of the cold

bath in a consumption; and I have heard of its having been used with

success, in the case of a negro man, in one of the West-India islands.

To render this remedy useful, or even safe, it will be necessary to

join it with labour, or to use it in degrees that shall prevent the

alternation of the system with vigour and debility; for I take the cure

of consumption ultimately to depend upon the simple and constant action

of tonic remedies. It is to be lamented that it often requires so much

time, or such remedies to remove the inflammatory diathesis, which

attends the first stage of consumption, as to reduce the patient too low

to make use of those tonic remedies afterwards, which would effect a

radical cure.

If it were possible to graduate the tone of the system by means of

a scale, I would add, that to cure consumption, the system should

be raised to the highest degree of this scale. Nothing short of an

equilibrium of tone, or a free and vigorous action of every muscle and

viscus in the body, will fully come up to a radical cure of this disease.

In regulating the diet of consumptive patients, I conceive it to be

as necessary to feel the pulse, as it is in determining when and in

what quantity to draw blood. Where inflammatory diathesis prevails,

a vegetable diet is certainly proper; but where the patient has

_escaped_, or _passed_ this stage of the disease, I believe a vegetable

diet alone to be injurious; and am sure a moderate quantity of animal

food may be taken with advantage.

The presence or absence of this inflammatory diathesis, furnishes the

indications for administering or refraining from the use of the bark

and balsamic medicines. With all the testimonies of their having done

mischief, many of which I could produce, I have known several cases in

which they have been given with obvious advantage; but it was only when

there was a total absence of inflammatory diathesis.

Perhaps the remedies I have recommended, and the opinions I have

delivered, may derive some support from attending to the analogy of

ulcers on the legs, and in other parts of the body. The first of these

occur chiefly in habits debilitated by spiritous liquors, and the last

frequently in habits debilitated by the scrophula. In curing these

diseases, it is in vain to depend upon internal or external medicines.

The whole system must be strengthened, or we do nothing; and this is to

be effected only by exercise and a generous diet.

In relating the facts that are contained in this inquiry, I wish I

could have avoided reasoning upon them; especially as I am confident of

the certainty of the facts, and somewhat doubtful of the truth of my

reasonings.

I shall only add, that if the cure of consumptions should at last be

effected by remedies in every respect the opposites of those palliatives

which are now fashionable and universal, no more will happen than what

we have already seen in the tetanus, the small-pox, and the management

of fractured limbs.

Should this be the case, we shall not be surprised to hear of

physicians, instead of prescribing any one, or all of the medicines

formerly enumerated for consumptions, ordering their patients to

exchange the amusements, or indolence of a city, for the toils

of a country life; of their advising farmers to exchange their

plentiful tables, and comfortable fire-sides, for the scanty but

solid subsistence, and midnight exposure of the herdsman; or of their

recommending, not so much the exercise of a _passive_ sea voyage, as

the _active_ labours and dangers of a common sailor. Nor should it

surprise us, after what we have seen, to hear patients relate the

pleasant adventures of their excursions or labours, in quest of their

recovery from this disease, any more than it does now to see a strong

or well-shaped limb that has been broken; or to hear a man talk of his

studies, or pleasures, during the time of his being inoculated and

attended for the small-pox.

I will not venture to assert, that there does not exist a medicine

which shall supply, at least in some degree, the place of the labour

or exercises, whose usefulness in consumptions has been established by

the facts that have been mentioned. Many instances of the analogous

effects of medicines, and of exercise upon the human body, forbid

the supposition. If there does exist in nature such a medicine, I am

disposed to believe it will be found in the class of TONICS. If this

should be the case, I conceive its strength, or its dose, must far

exceed the present state of our knowledge or practice, with respect to

the efficacy or dose of tonic medicines.

I except the disease, which arises from recent abscesses in the lungs,

from the general observation which has been made, respecting the

inefficacy of the remedies that were formerly enumerated for the cure

of consumptions without labour or exercise. These abscesses often

occur without being preceded by general debility, or accompanied by a

consumptive diathesis, and are frequently cured by nature, or by very

simple medicines.

OBSERVATIONS UPON WORMS

IN THE

ALIMENTARY CANAL,

AND UPON

ANTHELMINTIC MEDICINES.

With great diffidence I venture to lay before the public my opinions

upon worms: nor should I have presumed to do it, had I not entertained a

hope of thereby exciting further inquiries upon this subject.

When we consider how universally worms are found in all young animals,

and how frequently they exist in the human body, without producing

disease of any kind, it is natural to conclude, that they serve some

useful and necessary purposes in the animal economy. Do they consume the

superfluous aliment which all young animals are disposed to take, before

they have been taught, by experience or reason, the bad consequences

which arise from it? It is no objection to this opinion, that worms are

unknown in the human body in some countries. The laws of nature are

diversified, and often suspended under peculiar circumstances in many

cases, where the departure from uniformity is still more unaccountable,

than in the present instance. Do worms produce diseases from an _excess_

in their _number_, and an _error_ in their place, in the same manner

that blood, bile, and air produce diseases from an _error_ in their

place, or from _excess_ in their _quantities_? Before these questions

are decided, I shall mention a few facts which have been the result of

my own observations upon this subject.

1. In many instances, I have seen worms discharged in the small-pox and

measles, from children who were in perfect health previously to their

being attacked by those diseases, and who never before discovered a

single symptom of worms. I shall say nothing here of the swarms of worms

which are discharged in fevers of all kinds, until I attempt to prove

that an idiopathic fever is never produced by worms.

2. Nine out of ten of the cases which I have seen of worms, have been in

children of the grossest habits and most vigorous constitutions. This is

more especially the case where the worms are dislodged by the small-pox

and measles. Doctor Capelle of Wilmington, in a letter which I received

from him, informed me, that in the livers of sixteen, out of eighteen

rats which he dissected, he found a number of the tænia worms. The rats

were fat, and appeared in other respects to have been in perfect health.

The two rats in which he found no worms, he says, "were very lean, and

their livers smaller in proportion than the others."

3. In weakly children, I have often known the most powerful

anthelmintics given without bringing away a single worm. If these

medicines have afforded any relief, it has been by their tonic quality.

From this fact, is it not probable--the conjecture, I am afraid, is too

bold, but I will risk it:--is it not probable, I say, that children

are sometimes disordered from the want of worms? Perhaps the tonic

medicines which have been mentioned, render the bowels a more quiet and

comfortable asylum for them, and thereby provide the system with the

means of obviating the effects of crapulas, to which all children are

disposed. It is in this way that nature, in many instances, cures evil

by evil. I confine the salutary office of worms only to that species of

them which is known by the name of the round worm, and which occurs most

frequently in children.

Is there any such disease as an idiopathic WORM-FEVER? The Indians in

this country say there is not, and ascribe the discharge of worms to a

fever, and not a fever to the worms[40].

[40] See the Inquiry into the Diseases of the Indians, p. 19.

By adopting this opinion, I am aware that I contradict the observations

of many eminent and respectable physicians.

Doctor Huxham describes an epidemic pleurisy, in the month of March, in

the year 1740, which he supposes was produced by his patients feeding

upon some corn that had been injured by the rain the August before[41].

He likewise mentions that a number of people, and those too of the

elderly sort[42], were afflicted at one time with worms, in the month of

April, in the year 1743.

[41] Vol. II. of his Epidemics, p. 56.

[42] P. 136.

Lieutade gives an account of an epidemic worm-fever from Velchius,

an Italian physician[43]; and Sauvages describes, from Vandermonde,

an epidemic dysentery from worms, which yielded finally only to worm

medicines[44]. Sir John Pringle, and Doctor Monro, likewise frequently

mention worms as accompanying the dysentery and remitting fever, and

recommend the use of calomel as an antidote to them.

[43] Vol. I. p. 76.

[44] Vol. II. p. 329.

I grant that worms appear more frequently in some epidemic diseases

than in others, and oftener in some years than in others. But may not

the same heat, moisture, and diet which produced the diseases, have

produced the worms? And may not their discharge from the bowels have

been occasioned in those epidemics, as in the small-pox and measles,

by the increased heat of the body, by the want of nourishment, or by

an anthelmintic quality being accidentally combined with some of the

medicines that are usually given in fevers?

In answer to this, we are told that we often see the crisis of a fever

brought on by the discharge of worms from the bowels by means of a

purge, or by an anthelmintic medicine. Whenever this is the case, I

believe it is occasioned by offending bile being dislodged by means

of the purge, at the same time with the worms, or by the anthelmintic

medicine (if not a purge) having been given on, or near one of the usual

critical days of the fever. What makes the latter supposition probable

is, that worms are seldom suspected in the beginning of fevers, and

anthelmintic medicines seldom given, till every other remedy has failed

of success; and this generally happens about the usual time in which

fevers terminate in life or death.

It is very remarkable, that since the discovery and description of the

hydrocephalus internus, we hear and read much less than formerly of

worm-fevers. I suspect that disease of the brain has laid the foundation

for the principal part of the cases of worm-fevers which are upon record

in books of medicine. I grant that worms sometimes increase the danger

from fevers, and often confound the diagnosis and prognosis of them, by

a number of new and anomalous symptoms. But here we see nothing more

than that complication of symptoms which often occurs in diseases of a

very different and opposite nature.

Having rejected worms as the cause of fevers, I proceed to remark, that

the diseases most commonly produced by them, belong to Dr. Cullen's

class of NEUROSES. And here I might add, that there is scarcely a

disease, or a symptom of a disease, belonging to this class, which is

not produced by worms. It would be only publishing extracts from books,

to describe them.

The _chronic_ and _nervous_ diseases of children, which are so numerous

and frequently fatal, are, I believe, frequently occasioned by worms.

There is no great danger, therefore, of doing mischief, by prescribing

anthelmintic medicines in all our first attempts to cure their chronic

and nervous diseases.

I have been much gratified by finding myself supported in the above

theory of worm-fevers, by the late Dr. William Hunter, and by Dr.

Butter, in his excellent treatise upon the infantile remitting fever.

I have taken great pains to find out, whether the presence of the

different species of worms might not be discovered by certain peculiar

symptoms; but all to no purpose. I once attended a girl of twelve years

of age in a fever, who discharged four yards of a tænia, and who was

so far from having discovered any peculiar symptom of this species

of worms, that she had never complained of any other indisposition,

than now and then a slight pain in the stomach, which often occurs in

young girls from a sedentary life, or from errors in their diet. I

beg leave to add further, that there is not a symptom which has been

said to indicate the presence of worms of any kind, as the cause of

a disease, that has not deceived me; and none oftener than the one

that has been so much depended upon, viz. the picking of the nose. A

discharge of worms from the bowels, is, perhaps, the only symptom that

is pathognomonic of their presence in the intestines.

I shall now make a few remarks upon anthelmintic remedies.

But I shall first give an account of some experiments which I made

in the year 1771, upon the common earth-worm, in order to ascertain

the anthelmintic virtues of a variety of substances. I made choice of

the earth-worm for this purpose, as it is, according to naturalists,

nearly the same in its structure, manner of subsistence, and mode of

propagating its species, with the round worm of the human body.

In the first column I shall set down, under distinct heads, the

substances in which worms were placed; and in the second and third

columns the _time_ of their death, from the action of these substances

upon them.

I. BITTER AND ASTRINGENT | HOURS. | MINUTES.

SUBSTANCES. | |

| |

Watery infusion of aloes | 2 | 48

---- of rhubarb | 1 | 30

---- of Peruvian bark | 1 | 30

| |

II. PURGES. | |

| |

Watery infusion of jalap | 1 | --

------ bear's-foot | 1 | 17

------ gamboge | 1 | --

| |

III. SALTS. | |

| |

1. _Acids._ | |

| |

Vinegar | -- | 1-1/2 convulsed.

Lime juice | -- | 1

Diluted nitrous acid | -- | 1-1/2

| |

2. _Alkali._ | |

| |

A watery solution of salt of tartar | -- | 2 convulsed, throwing

| | up a mucus

| | on the surface of

3. _Neutral Salts._ | | the water.

| |

In a watery solution of common | |

salt | -- | 1 convulsed.

---- of nitre | -- | ditto.

---- of sal diuretic | -- | ditto.

---- of sal ammoniac | -- | 1-1/2

---- of common salt and sugar. | -- | 4

| |

4. _Earthy and metallic salts._ | |

| |

In a watery solution of Epsom salt | -- | 15-1/2

---- of rock alum | -- | 10

---- of corrosive sublimate | -- | 1-1/2 convulsed.

---- of calomel | -- | 49

---- of turpeth mineral | -- | 1 convulsed.

---- of sugar of lead | -- | 3

---- of green vitriol | -- | 1

---- of blue vitriol | -- | 10

---- of white vitriol | -- | 30

IV. METALS. | |

| |

Filings of steel | -- | 2-1/2

Filings of tin | 1 | --

| |

V. CALCAREOUS EARTH. | |

| |

Chalk | 2 | --

| |

VI. NARCOTIC SUBSTANCES. | |

| |

Watery infusion of opium | -- | 11-1/2 convulsed.

---- of Carolina pink-root | -- | 33

---- of tobacco | -- | 14

| |

VII. ESSENTIAL OILS. | |

| |

Oil of wormwood | -- | 3 convulsed.

---- of mint | -- | 3

---- of caraway seed | -- | 3

---- of amber | -- | 1-1/2

---- of anniseed | -- | 4-1/2

---- of turpentine | -- | 6

| |

VIII. ARSENIC. | |

| |

A watery solution of white | near |

arsenic | 2 | --

| |

IX. FERMENTED LIQUORS. | |

| |

In Madeira wine | -- | 3 convulsed.

Claret | -- | 10

| |

X. DISTILLED SPIRIT. | |

| |

Common rum | -- | 1 convulsed.

| |

XI. THE FRESH JUICES OF RIPE FRUITS. | |

| |

The juice of red cherries | -- | 5-1/2

---- of black do. | -- | 5

---- of red currants | -- | 2-1/2

---- of gooseberries | -- | 3-1/2

---- of whortleberries | -- | 12

---- of blackberries | -- | 7

---- of raspberries | -- | 5-1/2

---- of plums | -- | 13

---- of peaches | -- | 25

The juice of water-melons, no | |

effect. | -- | --

| |

XII. SACCHARINE SUBSTANCES. | |

| |

Honey | -- | 7

Molasses | -- | 7

Brown sugar | -- | 30

Manna | -- | 2-1/2

| |

XIII. IN AROMATIC SUBSTANCES. | |

| |

Camphor | -- | 5

Pimento | -- | 3-1/2

Black pepper | -- | 45

| |

XIV. FOETID SUBSTANCES | |

| |

Juice of onions | -- | 3-1/2

Watery infusion of assaf[oe]tida | -- | 27

---- Santonicum, or worm seed | 1 | --

| |

XV. MISCELLANEOUS SUBSTANCES. | |

| |

Sulphur mixed with oil | 2 | --

Æthiops mineral | 2 | --

Sulphur | 2 | --

Solution of gunpowder | -- | 1-1/2

---- of soap | -- | 19

Oxymel of squills | -- | 3-1/2

Sweet oil | 2 | 30

In the application of these experiments to the human body, an allowance

must always be made for the alteration which the several anthelmintic

substances that have been mentioned, may undergo from mixture and

diffusion in the stomach and bowels.

In order to derive any benefit from these experiments, as well as from

the observations that have been made upon anthelmintic medicines, it

will be necessary to divide them into such as act,

1. Mechanically,

2. Chemically upon worms; and,

3. Into those which possess a power composed of chemical and mechanical

qualities.

1. The mechanical medicines act indirectly and directly upon the worms.

Those which act _indirectly_ are, vomits, purges, bitter and astringent

substances, particularly aloes, rhubarb, bark, bear's-foot, and

worm-seed. Sweet oil acts indirectly and very feebly upon worms. It was

introduced into medicine from its efficacy in destroying the botts in

horses; but the worms which infest the human bowels, are of a different

nature, and possess very different organs of life from those which are

found in the stomach of a horse.

Those mechanical medicines which act _directly_ upon the worms, are

cowhage[45] and powder of tin. The last of these medicines has been

supposed to act chemically upon the worms, from the arsenic which

adheres to it; but from the length of time a worm lived in a solution of

white arsenic, it is probable the tin acts altogether mechanically upon

them.

[45] Dolichos Pruriens, of Linnæus.

2. The medicines which act chemically upon worms, appear, from our

experiments, to be very numerous.

Nature has wisely guarded children against the morbid effects of worms,

by implanting in them an early appetite for common salt, ripe fruits,

and saccharine substances; all of which appear to be among the most

speedy and effectual poisons for worms.

Let it not be said, that nature here counteracts her own purposes. Her

conduct in this business is conformable to many of her operations in the

human body, as well as throughout all her works. The bile is a necessary

part of the animal fluids, and yet an appetite for ripe fruits seems

to be implanted chiefly to obviate the consequences of its excess, or

acrimony, in the summer and autumnal months.

The use of common salt as an anthelmintic medicine, is both ancient and

universal. Celsus recommends it. In Ireland it is a common practice

to feed children, who are afflicted by worms, for a week or two upon

a salt-sea weed, and when the bowels are well charged with it, to

give a purge of wort in order to carry off the worms, after they are

debilitated by the salt diet.

I have administered many pounds of common salt coloured with cochineal,

in doses of half a drachm, upon an empty stomach in the morning, with

great success in destroying worms.

Ever since I observed the effects of sugar and other sweet substances

upon worms, I have recommended the liberal use of all of them in the

diet of children, with the happiest effects. The sweet substances

probably act in preventing the diseases from worms in the stomach only,

into which they often insinuate themselves, especially in the morning.

When we wish to dislodge worms from the bowels by sugar or molasses, we

must give these substances in large quantities, so that they may escape

in part the action of the stomach upon them.

I can say nothing from my own experience of the efficacy of the mineral

salts, composed of copper, iron, and zinc, combined with vitriolic

acid, in destroying worms in the bowels. Nor have I ever used the

corrosive sublimate in small doses as an anthelmintic.

I have heard of well-attested cases of the efficacy of the oil of

turpentine in destroying worms.

The expressed juices of onions and of garlic are very common remedies

for worms. From one of the experiments, it appears that the onion juice

possesses strong anthelmintic virtues.

I have often prescribed a tea-spoonful of gunpowder in the morning upon

an empty stomach, with obvious advantage. The active medicine here is

probably the nitre.

I have found a syrup made of the bark of the Jamaica cabbage-tree[46],

to be a powerful as well as a most agreeable anthelmintic medicine.

It sometimes purges and vomits, but its good effects may be obtained

without giving it in such doses as to produce these evacuations.

[46] Geoffrea, of Linnæus.

There is not a more _certain_ anthelmintic than Carolina pink-root[47].

But as there have been instances of death having followed excessive

doses of it, imprudently administered, and as children are often

affected by giddiness, stupor, and a redness and pain in the eyes after

taking it, I acknowledge that I have generally preferred to it, less

certain, but more safe medicines for destroying worms.

[47] Spigelia Marylandica, of Linnæus.

3. Of the medicines whose action is compounded of mechanical and

chemical qualities, calomel, jalap, and the powder of steel, are the

principal.

Calomel, in order to be effectual, must be given in large doses. It is

a safe and powerful anthelmintic. Combined with jalap, it often brings

away worms when given for other purposes.

Of all the medicines that I have administered, I know of none more safe

and certain than the simple preparations of iron, whether they be given

in the form of steel-filings or of the rust of iron. If ever they fail

of success, it is because they are given in too small doses. I generally

prescribe from five to thirty grains every morning, to children

between one year, and ten years old; and I have been taught by an old

sea-captain, who was cured of a tænia by this medicine, to give from two

drachms to half an ounce of it, every morning, for three or four days,

not only with safety, but with success.

I shall conclude this essay with the following remarks:

1. Where the action of medicines upon worms in the bowels does not agree

exactly with their action upon the earth-worms in the experiments that

have been related, it must be ascribed to the medicines being more or

less altered by the action of the stomach upon them. I conceive that the

superior anthelmintic qualities of pink-root, steel-filings, and calomel

(all of which acted but slowly upon the earth-worms compared with many

other substances) are in a great degree occasioned by their escaping the

digestive powers unchanged, and acting in a concentrated state upon the

worms.

2. In fevers attended with anomalous symptoms, which are supposed

to arise from worms, I have constantly refused to yield to the

solicitations of my patients, to abandon the indications of cure in the

fever, and to pursue worms as the _principal_ cause of the disease.

While I have adhered steadily to the usual remedies for the different

states of fever, in all their stages, I have at the same time blended

those remedies occasionally with anthelmintic medicines. In this I

have imitated the practice of physicians in many other diseases, in

which troublesome and dangerous symptoms are pursued, without seducing

the attention from the original disease. The anthelmintic medicines

prescribed in these cases, should not be the rust of iron, and common

salt, which are so very useful in chronic diseases from worms, but

calomel and jalap, and such other medicines as aid in the cure of

fevers.

AN ACCOUNT

OF THE

_EXTERNAL USE OF ARSENIC_,

IN THE

CURE OF CANCERS.

A few years ago, a certain Doctor Hugh Martin, a surgeon of one of the

Pennsylvania regiments stationed at Pittsburg, during the latter part

of the late war, came to this city, and advertised to cure cancers

with a medicine which he said he had discovered in the woods, in the

neighbourhood of the garrison. As Dr. Martin had once been my pupil,

I took the liberty of waiting upon him, and asked him some questions

respecting his discovery. His answers were calculated to make me

believe, that his medicine was of a vegetable nature, and that it was

originally an Indian remedy. He showed me some of the medicine, which

appeared to be the powder of a well-dried root of some kind. Anxious to

see the success of this medicine in cancerous sores, I prevailed upon

the doctor to admit me to see him apply it in two or three cases. I

observed, in some instances, he applied a powder to the parts affected,

and in others only touched them with a feather dipped in a liquid which

had a white sediment, and which he made me believe was the vegetable

root diffused in water. It gave me great pleasure to witness the

efficacy of the doctor's applications. In several cancerous ulcers, the

cures he performed were complete. Where the cancers were much connected

with the lymphatic system, or accompanied with a scrophulous habit of

body, his medicine always failed, and, in some instances, did evident

mischief.

Anxious to discover a medicine that promised relief in even a few cases

of cancers, and supposing that all the caustic vegetables were nearly

alike, I applied the phytolacca or poke-root, the stramonium, the arum,

and one or two others, to foul ulcers, in hopes of seeing the same

effects from them which I had seen from Doctor Martin's powder; but in

these I was disappointed. They gave some pain, but performed no cures.

At length I was furnished by a gentleman from Pittsburg with a powder

which I had no doubt, from a variety of circumstances, was of the same

kind as that used by Dr. Martin. I applied it to a fungous ulcer, but

without producing the degrees of pain, inflammation, or discharge,

which I had been accustomed to see from the application of Dr. Martin's

powder. After this, I should have suspected that the powder was not a

_simple_ root, had not the doctor continued upon all occasions to assure

me, that it was wholly a vegetable preparation.

In the beginning of the year 1784, the doctor died, and it was generally

believed that his medicine had died with him. A few weeks after his

death I procured, from one of his administrators, a few ounces of the

doctor's powder, partly with a view of applying it to a cancerous sore

which then offered, and partly with a view of examining it more minutely

than I had been able to do during the doctor's life. Upon throwing the

powder, which was of a brown colour, upon a piece of white paper, I

perceived distinctly a number of white particles scattered through it.

I suspected at first that they were corrosive sublimate, but the usual

tests of that metallic salt soon convinced me, that I was mistaken.

Recollecting that arsenic was the basis of most of the celebrated cancer

powders that have been used in the world, I had recourse to the tests

for detecting it. Upon sprinkling a small quantity of the powder upon

some coals of fire, it emitted the garlick smell so perceptibly as to

be known by several persons whom I called into the room where I made the

experiment, and who knew nothing of the object of my inquiries. After

this, with some difficulty I picked out about three or four grains of

the white powder, and bound them between two pieces of copper, which

I threw into the fire. After the copper pieces became red hot, I took

them out of the fire, and when they had cooled, discovered an evident

whiteness imparted to both of them. One of the pieces afterwards looked

like dull silver. These two tests have generally been thought sufficient

to distinguish the presence of arsenic in any bodies; but I made use of

a third, which has lately been communicated to the world by Mr. Bergman,

and which is supposed to be in all cases infallible.

I infused a small quantity of the powder in a solution of a vegetable

alkali in water for a few hours, and then poured it upon a solution of

blue vitriol in water. The colour of the vitriol was immediately changed

to a beautiful green, and afterwards precipitated.

I shall close this paper with a few remarks upon this powder, and upon

the cure of cancers and foul ulcers of all kinds.

1. The use of caustics in cancers and foul ulcers is very ancient, and

universal. But I believe _arsenic_ to be the most efficacious of any

that has ever been used. It is the basis of Plunket's and probably

of Guy's well-known cancer powders. The great art of applying it

successfully, is to dilute and mix it in such a manner as to mitigate

the violence of its action. Doctor Martin's composition was happily

calculated for this purpose. It gave less pain than the common or

lunar caustic. It excited a moderate inflammation, which separated

the morbid from the sound parts, and promoted a plentiful afflux of

humours to the sore during its application. It seldom produced an escar;

hence it insinuated itself into the deepest recesses of the cancers,

and frequently separated those fibres in an unbroken state, which are

generally called the roots of the cancer. Upon this account, I think,

in some ulcerated cancers it is to be preferred to the knife. It has

no action upon the sound skin. This Doctor Hall proved, by confining a

small quantity of it upon his arm for many hours. In those cases where

Doctor Martin used it to extract cancerous or schirrous tumours that

were not ulcerated, I have reason to believe that he always broke the

skin with Spanish flies.

2. The arsenic used by the doctor was the pure white arsenic. I should

suppose from the examination I made of the powder with the eye, that the

proportion of arsenic to the vegetable powder, could not be more than

one-fortieth part of the whole compound. I have reason to think that the

doctor employed different vegetable substances at different times. The

vegetable matter with which the arsenic was combined in the powder which

I used in my experiments, was probably nothing more than the powder of

the root and berries of the solanum lethale, or deadly nightshade. As

the principal, and perhaps the only design of the vegetable addition

was to blunt the activity of the arsenic, I should suppose that the

same proportion of common wheat flour as the doctor used of his caustic

vegetables, would answer nearly the same purpose. In those cases where

the doctor applied a feather dipped in a liquid to the sore of his

patient, I have no doubt but his phial contained nothing but a weak

solution of arsenic in water. This is no new method of applying arsenic

to foul ulcers. Doctor Way of Wilmington has spoken in the highest terms

to me of a wash for foulnesses on the skin, as well as old ulcers,

prepared by boiling an ounce of white arsenic in two quarts of water to

three pints, and applying it once or twice a day.

3. I mentioned, formerly, that Doctor Martin was often unsuccessful

in the application of his powder. This was occasioned by his using it

indiscriminately in _all_ cases. In schirrous and cancerous tumours, the

knife should always be preferred to the caustic. In cancerous ulcers

attended with a scrophulous or a bad habit of body, such particularly

as have their seat in the neck, in the breasts of females, and in the

axillary glands, it can only protract the patient's misery. Most of

the cancerous sores cured by Doctor Martin were seated on the nose, or

cheeks, or upon the surface or extremities of the body. It remains yet

to discover a cure for cancers that taint the fluids, or infect the

whole lymphatic system. This cure I apprehend must be sought for in

diet, or in the long use of some internal medicine.

To pronounce a disease incurable, is often to render it so. The

intermitting fever, if left to itself, would probably prove frequently,

and perhaps more speedily fatal than cancers. And as cancerous tumours

and sores are often neglected, or treated improperly by injudicious

people, from an apprehension that they are incurable (to which the

frequent advice of physicians "to let them alone," has no doubt

contributed), perhaps the introduction of arsenic into regular practice

as a remedy for cancers, may invite to a more early application to

physicians, and thereby prevent the deplorable cases that have been

mentioned, which are often rendered so by delay or unskilful management.

4. It is not in cancerous sores only that Doctor Martin's powder has

been found to do service. In sores of all kinds, and from a variety of

causes, where they have been attended with fungous flesh or callous

edges, I have used the doctor's powder with advantage.

I flatter myself that I shall be excused in giving this detail of a

_quack_ medicine, when we reflect that it was from the inventions and

temerity of quacks, that physicians have derived some of their most

active and most useful medicines.

OBSERVATIONS

UPON

_THE TETANUS_.

For a history of the different names and symptoms of this disease, I beg

leave to refer the reader to practical books, particularly to Doctor

Cullen's First Lines. My only design in this inquiry, is to deliver such

a theory of the disease, as may lead to a new and successful use of old

and common remedies for it.

All the remote and predisposing causes of the tetanus act by inducing

preternatural debility, and irritability in the muscular parts of

the body. In many cases, the remote causes act alone, but they more

frequently require the co-operation of an exciting cause. I shall

briefly enumerate, without discriminating them, or pointing out when

they act singly, or when in conjunction with each other.

I. Wounds on different parts of the body are the most frequent causes

of this disease. It was formerly supposed it was the effect only of a

wound, which partially divided a tendon, or a nerve; but we now know

it is often the consequence of læsions which affect the body in a

superficial manner. The following is a list of such wounds and læsions

as have been known to induce the disease:

1. Wounds in the soles of the feet, in the palms of the hands, and under

the nails, by means of nails or splinters of wood.

2. Amputations, and fractures of limbs.

3. Gun-shot wounds.

4. Venesection.

5. The extraction of a tooth, and the insertion of new teeth.

6. The extirpation of a schirrous.

7. Castration.

8. A wound on the tongue.

9. The injury which is done to the feet by frost.

10. The injury which is sometimes done to one of the toes, by stumping

it (as it is called) in walking.

11. Cutting a nail too closely. Also,

12. Cutting a corn too closely.

13. Wearing a shoe so tight as to abrade the skin of one of the toes.

14. A wound, not more than an eighth part of an inch, upon the forehead.

15. The stroke of a whip upon the arm, which only broke the skin.

16. Walking too soon upon a broken limb.

17. The sting of a wasp upon the glands penis.

18. A fish bone sticking in the throat.

19. Cutting the navel string in new-born infants.

Between the time in which the body is thus wounded or injured, and the

time in which the disease makes its appearance, there is an interval

which extends from one day to six weeks. In the person who injured his

toe by stumping it in walking, the disease appeared the next day. The

trifling wound on the forehead which I have mentioned, produced both

tetanus and death, the day after it was received. I have known two

instances of tetanus, from running nails in the feet, which did not

appear until six weeks afterwards. In most of the cases of this disease

from wounds which I have seen, there was a total absence of pain and

inflammation, or but very moderate degrees of them, and in some of

them the wounds had entirely healed, before any of the symptoms of the

disease had made their appearance. Wounds and læsions are most apt to

produce tetanus, after the long continued application of heat to the

body; hence its greater frequency, from these causes, in warm than in

cold climates, and in warm than in cold weather, in northern countries.

II. Cold applied suddenly to the body, after it has been exposed to

intense heat. Of this Dr. Girdlestone mentions many instances, in his

Treatise upon Spasmodic Affections in India. It was most commonly

induced by sleeping upon the ground, after a warm day. Such is the

dampness and unwholesome nature of the ground, in some parts of that

country, that "fowls (the doctor says) put into coops at night, in the

sickly season of the year, and on the same soil that the men slept,

were always found dead the next morning, if the coop was not placed at

a certain height above the surface of the earth[48]." It was brought

on by sleeping on a damp pavement in a servant girl of Mr. Alexander

Todd of Philadelphia, in the evening of a day in which the mercury in

Fahrenheit's thermometer stood at 90°. Dr. Chalmers relates an instance

of its having been induced by a person's sleeping without a nightcap,

after shaving his head. The late Dr. Bartram informed me, that he

had known a draught of cold water produce it in a man who was in a

preternaturally heated state. The cold air more certainly brings on this

disease, if it be applied to the body in the form of a current. The

stiff neck which is sometimes felt after exposure to a stream of cool

air from an open window, is a tendency to a locked jaw, or a feeble and

partial tetanus.

[48] Page 55.

III. Worms and certain acrid matters in the alimentary canal. Morgagni

relates an instance of the former, and I shall hereafter mention

instances of the latter in new-born infants.

IV. Certain poisonous vegetables. There are several cases upon record of

its being induced by the hemlock dropwort, and the datura stramonium, or

Jamestown weed of our country.

V. It is sometimes a symptom of the bilious remitting and intermitting

fever. It is said to occur more frequently in those states of fever in

the island of Malta, than in any other part of the world.

VI. It is likewise a symptom of that malignant state of fever which is

brought on by the bite of a rabid animal, also of hysteria and gout.

VII. The grating noise produced by cutting with a knife upon a pewter

plate excited it in a servant, while he was waiting upon his master's

table in London. It proved fatal in three days.

VIII. The sight of food, after long fasting.

IX. Drunkenness.

X. Certain emotions and passions of the mind. Terror brought it on

a brewer in this city. He had been previously debilitated by great

labour, in warm weather. I have heard of its having been induced in a

man by agitation of mind, occasioned by seeing a girl tread upon a nail.

Fear excited it in a soldier who kneeled down to be shot. Upon being

pardoned he was unable to rise, from a sudden attack of tetanus. Grief

produced it in a case mentioned by Dr. Willan.

XI. Parturition.

All these remote and exciting causes act with more or less certainty and

force, in proportion to the greater or less degrees of fatigue which

have preceded them.

It has been customary with authors to call all those cases of tetanus,

which are not brought on by wounds, symptomatic. They are no more so

than those which are said to be idiopathic. They all depend alike upon

irritating impressions, made upon one part of the body, producing

morbid excitement, or disease in another. It is immaterial, whether

the impression be made upon the intestines by a worm, upon the ear by

an ungrateful noise, upon the mind by a strong emotion, or upon the

sole of the foot by a nail; it is alike communicated to the muscles,

which, from their previous debility and irritability, are thrown into

commotions by it. In yielding to the impression of irritants, they

follow in their contractions the order of their predisposing debility.

The muscles which move the lower jaw are affected more early, and more

obstinately than any of the other external muscles of the body, only

because they are more constantly in a relaxed, or idle state.

The negroes in the West-Indies are more subject to this disease than

white people. This has been ascribed to the greater irritability of

their muscular systems, which constitutes a part of its predisposing

cause. It is remarkable that their sensibility lessens with the increase

of their irritability; and hence, Dr. Moseley says, they bear surgical

operations much better than white people.

New-born infants are often affected by this disease in the West-Indies.

I have seen a few cases of it in Philadelphia. It is known by the name

of the jaw-fall. Its causes are:

1. The cutting of the navel string. This is often done with a pair of

dull scissors, by which means the cord is bruised.

2. The acrimony of the meconium retained in the bowels.

3. Cold air acting upon the body, after it has been heated by the air of

a hot room.

4. Smoke is supposed to excite it, in the negro quarters in the

West-Indies.

It is unknown, Dr. Winterbottom informs us, among the native Africans in

the neighbourhood of Sierra Leone.

I am aware that it is ascribed by many physicians to only one of the

above causes; but I see no reason why it should not be induced by

more than one cause in infants, when we see it brought on by so many

different causes in grown people.

The tetanus is not confined to the human species. It often affects

horses in the West-Indies. I have seen several cases of it in

Philadelphia.

The want of uniform success in the treatment of this disease, has long

been a subject of regret among physicians. It may be ascribed to the use

of the same remedies, without any respect to the nature of the causes

which produce it, and to an undue reliance upon some one remedy, under

a belief of its specific efficacy. Opium has been considered as its

antidote, without recollecting that it was one only, of a numerous class

of medicines, that are all alike useful in it.

Tetanus, from all its causes, has nearly the same premonitory symptoms.

These are a stiffness in the neck, a disposition to bend forward, in

order to relieve a pain in the back, costiveness, a pain about the

external region of the stomach, and a disposition to start in sleep. In

this feeble state of the disease, an emetic, a strong dose of laudanum,

the warm bath, or a few doses of bark, have often prevented its being

completely formed. When it has arisen from a wound, dilating it if small

or healed, and afterwards inflaming it, by applying to it turpentine,

common salt, corrosive sublimate, or Spanish flies, have, in many

hundred instances, been attended with the same salutary effects.

The disease I have said is seated in the muscles, and, while they are

preternaturally excited, the blood-vessels are in a state of reduced

excitement. This is evident from the feebleness and slowness of the

pulse. It sometimes beats, according to Dr. Lining, but forty strokes

in a minute. By stimulating the wound, we not only restore the natural

excitement of the blood-vessels, but we produce an inflammatory

diathesis in them, which abstracts morbid excitement from the muscular

system, and, by equalizing it, cures the disease. This remedy I

acknowledge has not been as successfully employed in the West-Indies as

in the United States, and that for an obvious reason. The blood-vessels

in a warm climate refuse to assume an inflammatory action. Stimuli hurry

them on suddenly to torpor or gangrene. Hence the danger and even fatal

effects of blood-letting, in the fevers which affect the natives of the

islands, a few hours after they are formed. But widely different is

the nature of wounds, and of the tension of the blood-vessels, in the

inhabitants of northern countries. While Dr. Dallas deplores the loss

of 49 out of 50 affected with tetanus from wounds, in the West-India

islands, I am sure I could mention many hundred instances of the

disease being prevented, and a very different proportion of cures being

performed, by inflaming the wounds, and exciting a counter _morbid_

action in the blood-vessels.

When the disease is the effect of fever, the same remedies should be

given, as are employed in the cure of that fever. I have once unlocked

the jaw of a woman who was seized at the same time with a remitting

fever, by an emetic, and I have heard of its being cured in a company

of surveyors, in whom it was the effect of an intermittent, by large

doses of bark. When it accompanies malignant fever, hysteria, or gout,

the remedies for those forms of disease should be employed. Bleeding

was highly useful in it in a case of yellow fever which occurred in

Philadelphia in the year 1794.

When it is produced by the suppression of perspiration by means of cold,

the warm bath and sweating medicines have been found most useful in it.

Nature has in one instance pointed out the use of this remedy, by curing

the disease by a miliary eruption on the skin[49].

[49] Burserus.

If it be the effect of poisonous substances taken into the stomach, or

of worms in the bowels, the cure should be begun by emetics, purges, and

anthelmintic medicines.

Where patients are unable to swallow, from the teeth of the upper and

lower jaw pressing upon each other, a tooth or two should be extracted,

to open a passage for our medicines into the throat. If this be

impracticable or objected to, they should be injected by way of glyster.

In the locked jaw which arises from the extraction of a tooth, an

instrument should be introduced to depress the jaw. This has been done

by a noted English dentist in London, with success.

As the habit of diseased action often continues after the removal of its

causes, and as some of the remote causes of this disease are beyond the

reach of medicine, such remedies should be given as are calculated, by

their stimulating power, to overcome the morbid or spasmodic action of

the muscles. These are:

1. OPIUM. It should be given in large and frequent doses. Dr. Streltz

says he has found from one to two drachms of an alkali, taken in the

course of a day, greatly to aid the action of the opium in this disease.

2. WINE. This should be given in quarts, and even gallons daily. Dr.

Currie relates a case of a man in the infirmary of Liverpool, who was

cured of tetanus, by drinking nearly a quarter cask of Madeira wine.

Dr. Hosack speaks in high terms of it, in a letter to Dr. Duncan, and

advises its being given without any other stimulating medicine.

3. ARDENT SPIRITS. A quack in New-England has lately cured tetanus, by

giving ardent spirits in such quantities as to produce intoxication.

Upon being asked his reason for this strange practice, he said, he had

always observed the jaw to fall in drunken men, and any thing that would

produce that effect, he supposed to be proper in the locked jaw.

4. The BARK has of late years been used in this disease with success. I

had the pleasure of first seeing its good effects in the case of Colonel

Stone, in whom a severe tetanus followed a wound in the foot, received

at the battle of Germantown, in October, 1777.

5. The COLD BATH. This remedy has been revived by Dr. Wright of Jamaica,

and has in many instances performed cures of this disease. In one of two

cases in which I have used it with success, the patient's jaw opened in

a few minutes after the affusion of a single bucket of water upon her

body. The disease was occasioned by a slight injury done to one of her

toes, by wearing a tight shoe. The signals for continuing the use of the

cold bath, are its being followed by a slight degree of fever, and a

general warmth of the skin. Where these do not occur, there is reason

to believe it will do no service, or perhaps do harm. We have many

proofs of the difference in the same disease, and in the operation of

the same medicine, in different and opposite climates. Dr. Girdlestone

has mentioned the result of the use of the cold bath in tetanus in

the East-Indies, which furnishes a striking addition to the numerous

facts that have been collected upon that subject. He tells us the cold

bath uniformly destroyed life, in every case in which it was used. The

reason is obvious. In that extremely debilitating climate, the system in

tetanus was prostrated too low to re-act, under the sedative operation

of the cold water.

6. The WARM BATH has often been used with success in this disease. Its

temperature should be regulated by our wishes to promote sweats, or to

produce excitement in the blood-vessels. In the latter case it should

rise above the heat of the human body.

7. The OIL OF AMBER acts powerfully upon the muscular system. I have

seen the happiest effects from the exhibition of six or eight drops of

it, every two hours, in this disease.

8. A SALIVATION has been often recommended for the cure of tetanus, but

unfortunately it can seldom be excited in time to do service. I once saw

it complete the cure of a sailor in the Pennsylvania hospital, whose

life was prolonged by the alternate use of bark and wine. The disease

was brought on him by a mortification of his feet, in consequence of

their being frost-bitten.

9. Dr. Girdlestone commends BLISTERS in high terms in this disease.

He says he never saw it prove fatal, even where they only produced a

redness on the skin.

10. I have heard of ELECTRICITY having been used with advantage in

tetanus, but I can say nothing in its favour from my own experience.

In order to ensure the utmost benefit from the use of the above

remedies, it will be necessary for a physician always to recollect, that

the disease is attended with great morbid action, and of course each of

the stimulating medicines that has been mentioned should be given, 1st,

in large doses; 2dly, in succession; 3dly, in rotation; and 4thly, by

way of glyster, as well as by the mouth.

The jaw-fall in new-born infants is, I believe, always fatal. Purging

off the meconium from the bowels immediately after birth has often

prevented it from one of its causes; and applying a rag wetted with

spirit of turpentine to the navel-string, immediately after it is cut,

Dr. Chisholm says, prevents it from another of its causes which has been

mentioned.

This disease, I have said, sometimes affects horses. I have twice seen

it cured by applying a potential caustic to the neck under the mane,

by large doses of the oil of amber, and by plunging one of them into a

river, and throwing buckets of cold water upon the other.

I shall conclude my observations upon the tetanus with the following

queries:

1. What would be the effects of _copious_ blood-letting in this disease?

There is a case upon record of its efficacy, in the Medical Journal

of Paris, and I have now in my possession a letter from the late Dr.

Hopkins of Connecticut, containing the history of a cure performed by

it. Where tetanus is the effect of primary gout, hysteria, or fever,

attended with highly inflammatory symptoms, bleeding is certainly

indicated, but, in general, the disease is so completely insulated in

the muscles, and the arteries are so far below their par of excitement

in frequency and force, that little benefit can be expected from that

remedy. The disease, in these cases, seems to call for an elevation,

instead of a diminution, of the excitement of the blood-vessels.

2. What would be the effect of _extreme_ cold in this disease? Mr. John

Hunter used to say, in his lectures, "Were he to be attacked by it,

he would, if possible, fly to Nova-Zembla, or throw himself into an

ice-house." I have no doubt of the efficacy of intense cold, in subduing

the inordinate morbid actions which occur in the muscular system; but

it offers so much violence to the fears and prejudices of sick people,

or their friends, that it can seldom be applied in such a manner as to

derive much benefit from it. Perhaps the sedative effects of cold might

be obtained with less difficulty, by wrapping the body in sheets, and

wetting them occasionally for an hour or two with cold water.

3. What would be the effect of exciting a strong counter-action in

the stomach and bowels in this disease? Dr. Brown of Kentucky cured

a tetanus by inflaming the stomach, by means of the tincture of

cantharides. It has likewise been cured by a severe cholera morbus,

induced by a large dose of corrosive sublimate. The stomach and bowels,

and the external muscles of the body, discover strong associations in

many diseases. A sick stomach is always followed by general weakness,

and the dry gripes often paralyze the muscles of the arms and limbs. But

further, one of the remote causes of tetanus, viz. cold air, often shows

the near relationship of the muscles to the bowels, and the vicarious

nature of disease in each of them. It often produces in the latter, in

the West-Indies, what the French physicians call a "crampe seche," or,

in other words, if I may be allowed the expression, a tetanus in the

bowels.

4. A sameness has been pointed out between many of the symptoms of

hydrophobia and tetanus. A similar difficulty of swallowing, and similar

convulsions after it, have been remarked in both diseases. Death often

takes place suddenly in tetanus, as it does in hydrophobia, without

producing marks of fatal disorganization in any of the internal parts

of the body. Dr. Physick supposes death in these cases to be the

effect of suffocation, from a sudden spasm and closure of the glottis,

and proposes to prevent it in the same manner that he has proposed

to prevent death from hydrophobia, that is, by laryngotomy[50]. The

prospect of success from it appears alike reasonable in both cases.

[50] Medical Repository.

THE RESULT OF OBSERVATIONS

MADE UPON

_THE DISEASES_

WHICH OCCURRED IN

THE MILITARY HOSPITALS

OF THE UNITED STATES,

DURING THE REVOLUTIONARY WAR BETWEEN GREAT BRITAIN

AND THE UNITED STATES.

1. The army when in tents, was always more sickly, than in the open air.

It was likewise more healthy when it was kept in motion, than when it

lay in an encampment.

2. Young men under twenty years of age, were subject to the greatest

number of camp diseases.

3. The southern troops were more sickly than the northern or eastern

troops.

4. The native Americans were more sickly than the natives of Europe who

served in the American army.

5. Men above thirty, and five and thirty years of age, were the hardiest

soldiers in the army. Perhaps the reason why the natives of Europe were

more healthy than the native Americans, was, they were more advanced in

life.

6. The southern troops sickened from the want of salt provisions. Their

strength and spirits were restored only by means of salted meat. I once

saw a private in a Virginia regiment, throw away his ration of choice

fresh beef, and give a dollar for a pound of salted bacon.

7. Those officers who wore flannel shirts or waistcoats next to their

skins, in general escaped fevers and diseases of all kinds.

8. The principal diseases in the hospitals were the typhus gravior and

mitior of Doctor Cullen. Men who came into the hospitals with pleurisies

or rheumatisms, soon lost the types of their original diseases, and

suffered, or died, by the above-mentioned states of fever.

9. The typhus mitior always prevailed most, and with the worst symptoms

in winter. A free air, which could only be obtained in summer, always

prevented, or mitigated it.

10. In all those cases, where the contagion was received, cold seldom

failed to render it active. Whenever an hospital was removed in winter,

one half of the patients generally sickened on the way, or soon after

their arrival at the place to which they were sent.

11. Drunken soldiers and convalescents were most subject to this fever.

12. Those patients in this fever who had large ulcers on their back or

limbs, generally recovered.

13. I met with several instances of buboes, also of ulcers in the

throat, as described by Doctor Donald Monro. They were mistaken by some

of the junior surgeons for venereal sores, but they yielded to the

common remedies of the hospital fever.

14. There were many instances of patients in this fever, who suddenly

fell down dead, upon being moved, without any previous symptoms of

approaching dissolution. This was more especially the case, when they

arose to go to stool.

15. The contagion of this fever was frequently conveyed from the

hospital to the camp, by means of blankets and clothes.

16. Those black soldiers who had been previously slaves, died in a

greater proportion by this fever, or had a much slower recovery from it,

than the same number of white soldiers.

17. The remedies which appeared to do most service in this disease were

vomits of tartar emetic, gentle dozes of laxative salts, bark, wine,

volatile salt, opium, and blisters.

18. An emetic seldom failed of checking this fever if exhibited while it

was in a _forming_ state, and before the patient was confined to his bed.

19. Many causes concurred to produce, and increase this fever; such as

the want of cleanliness, excessive fatigue, the ignorance or negligence

of officers in providing suitable diet and accommodations for their

men, the general use of linen instead of woollen clothes in the summer

months, and the crowding too many patients together in one hospital,

with such other inconveniences and abuses, as usually follow the union

of the _purveying_ and _directing_ departments of hospitals in the

_same_ persons. But there is one more cause of this fever which remains

to be mentioned, and that is, the sudden assembling of a great number of

persons together of different habits and manners, such as the soldiers

of the American army were in the years 1776 and 1777. Doctor Blane

informs us, in his observations upon the diseases of seamen, "that it

sometimes happens that a ship with a long established crew shall be very

_healthy_, yet if strangers are introduced among them, who are also

_healthy_, sickness will be mutually produced." The history of diseases

furnishes many proofs of the truth of this assertion[51]. It is very

remarkable, that while the American army at Cambridge, in the year 1775,

consisted only of New-Englandmen (whose habits and manners were the

same) there was scarcely any sickness among them. It was not till the

troops of the eastern, middle, and southern states met at New-York and

Ticonderoga, in the year 1776, that the typhus became universal, and

spread with such peculiar mortality in the armies of the United States.

[51] "Cleanliness is founded on a natural aversion to what is unseemly

and offensive in the persons of others; and there seems also to

be an instinctive horror at strangers implanted in human nature

for the same purpose, as is visible in young children, and

uncultivated people. In the early ages of Rome, the same word

signified both a stranger and an enemy." Dr. Blane, p. 225.

20. The dysentery prevailed, in the summer of 1777, in the military

hospitals of New-Jersey, but with very few instances of mortality. This

dysentery was frequently followed by an obstinate diarrh[oe]a, in which

the warm bath was found in many cases to be an effectual remedy.

21. I saw several instances of fevers occasioned by the use of the

common ointment made of the flour of sulphur and hog's lard, for the

cure of the itch. The fevers were probably brought on by the exposure of

the body to the cold air, in the usual method in which that ointment is

applied. I have since learned, that the itch may be cured as speedily by

rubbing the parts affected, two or three times, with the dry flour of

sulphur, and that no inconvenience, and scarcely any smell, follow this

mode of using it.

22. In gun-shot wounds of the joints, Mr. Ranby's advice of amputating

the limb was followed with success. I saw two cases of death where this

advice was neglected.

23. There was one instance of a soldier who lost his hearing, and

another of a soldier who had been deaf who recovered his hearing, by the

noise of artillery in a battle.

24. Those soldiers who were billetted in private houses, generally

escaped the hospital fever, and recovered soonest from all their

diseases.

25. Hospitals built of coarse logs, with _ground_ floors, with

fire-places in the middle of them, and a hole in the roof, for the

discharge of smoke, were found to be very conducive to the recovery of

the soldiers from the hospital fever. This form of a military hospital

was introduced into the army by Dr. Tilton of the state of Delaware[52].

[52] "It is proved, in innumerable instances, that sick men recover

health sooner and better in sheds, huts, and barns, exposed

occasionally to wind, and sometimes to rain, than in the

most superb hospitals in Europe." Jackson's Remarks on the

Constitution of the Medical Department of the British Army,

p. 340.

26. In fevers and dysenteries, those soldiers recovered most certainly,

and most speedily, who lay at the greatest distance from the walls of

the hospitals. This important fact was communicated to me by the late

Dr. Beardsley of Connecticut.

27. Soldiers are but little more than adult children. That officer,

therefore, will best perform his duty to his men, who obliges them to

take the most care of their HEALTH.

28. Hospitals are the sinks of human life in an army. They robbed the

United States of more citizens than the sword. Humanity, economy, and

philosophy, all concur in giving a preference to the conveniences and

wholesome air of private houses; and should war continue to be the

absurd and unchristian mode of deciding national disputes, it is to

be hoped that the progress of science will so far mitigate one of its

greatest calamities, as to produce an abolition of hospitals for acute

diseases. Perhaps there are no cases of sickness in which reason and

religion do not forbid the seclusion of our fellow creatures from the

offices of humanity in private families, except where they labour under

the calamities of madness and the venereal disease, or where they are

the subjects of some of the operations of surgery.

AN ACCOUNT OF THE INFLUENCE

OF THE

MILITARY AND POLITICAL EVENTS

OF THE

_AMERICAN REVOLUTION_

UPON THE

HUMAN BODY.

There were several circumstances peculiar to the American revolution,

which should be mentioned previously to an account of the influence of

the events which accompanied it, upon the human body.

1. The revolution interested every inhabitant of the country of both

sexes, and of every rank and age that was capable of reflection. An

indifferent, or neutral spectator of the controversy, was scarcely to be

found in any of the states.

2. The scenes of war and government which it introduced, were new to the

greatest part of the inhabitants of the United States, and operated with

all the force of _novelty_ upon the human mind.

3. The controversy was conceived to be the most important of any that

had ever engaged the attention of mankind. It was generally believed, by

the friends of the revolution, that the very existence of _freedom_ upon

our globe, was involved in the issue of the contest in favour of the

United States.

4. The American revolution included in it the cares of government, as

well as the toils and dangers of war. The American mind was, therefore,

frequently occupied at the _same time_, by the difficult and complicated

duties of political and military life.

5. The revolution was conducted by men who had been born _free_, and

whose sense of the blessings of liberty was of course more exquisite

than if they had just emerged from a state of slavery.

6. The greatest part of the soldiers in the armies of the United States

had family connections and property in the country.

7. The war was carried on by the Americans against a nation, to whom

they had long been tied by the numerous obligations of consanguinity,

laws, religion, commerce, language, interest, and a mutual sense of

national glory. The resentments of the Americans of course rose, as is

usual in all disputes, in proportion to the number and force of these

ancient bonds of affection and union.

8. A predilection to a limited monarchy, as an essential part of a

free and safe government, and an attachment to the reigning king of

Great-Britain (with a very few exceptions), were universal in every part

of the United States.

9. There was at one time a sudden dissolution of civil government in

_all_, and of ecclesiastical establishments in several of the states.

10. The expences of the war were supported by means of a paper currency,

which was continually depreciating.

From the action of each of these causes, and frequently from their

combination in the same persons, effects might reasonably be expected,

both upon the mind and body, which have seldom occurred; or if they

have, I believe were never fully recorded in any age or country.

It might afford some useful instruction, to point out the influence

of the military and political events of the revolution upon the

understandings, passions, and morals of the citizens of the United

States; but my business in the present inquiry, is only to take notice

of the influence of those events upon the human body, through the medium

of the mind.

I shall first mention the effects of the military, and secondly, of the

political events of the revolution. The last must be considered in a

two-fold view, accordingly as they affected the friends, or the enemies

of the revolution.

I. In treating of the effects of the military events, I shall take

notice, first, of the influence of _actual_ war, and, secondly, of the

influence of the military life.

In the beginning of a battle, I have observed _thirst_ to be a very

common sensation among both officers and soldiers. It occurred where no

exercise, or action of the body, could have excited it.

Many officers have informed me, that after the first onset in a battle,

they felt a glow of heat, so universal as to be perceptible in both

their ears. This was the case, in a particular manner, in the battle of

Princeton, on the third of January, in the year 1777, on which day the

weather was remarkably cold.

A veteran colonel of a New-England regiment, whom I visited at

Princeton, and who was wounded in the hand at the battle of Monmouth,

on the 28th of June, 1778 (a day in which the mercury stood at 90° of

Fahrenheit's thermometer), after describing his situation at the time

he received his wound, concluded his story by remarking, that "fighting

was hot work on a cold day, but much more so on a warm day." The many

instances which appeared after that memorable battle, of soldiers who

were found among the slain without any marks of wounds or violence upon

their bodies, were probably occasioned by the heat excited in the body,

by the emotions of the mind, being added to that of the atmosphere.

Soldiers bore operations of every kind immediately _after_ a battle,

with much more fortitude than they did at _any time_ afterwards.

The effects of the military life upon the human body come next to be

considered under this head.

In another place[53] I have mentioned three cases of pulmonary

consumption being perfectly cured by the diet and hardships of a camp

life.

[53] Page 204.

Doctor Blane, in his valuable observations on the diseases incident to

seamen, ascribes the extraordinary healthiness of the British fleet in

the month of April, 1782, to the effects produced on the spirit of the

soldiers and seamen, by the victory obtained over the French fleet on

the 12th of that month; and relates, upon the authority of Mr. Ives,

an instance in the war between Great-Britain and the combined powers

of France and Spain, in 1744, in which the scurvy, as well as other

diseases, were checked by the prospect of a naval engagement.

The American army furnished an instance of the effects of victory upon

the human mind, which may serve to establish the inferences from the

facts related by Doctor Blane. The Philadelphia militia who joined the

remains of General Washington's army, in December, 1776, and shared with

them a few days afterwards in the capture of a large body of Hessians at

Trenton, consisted of 1500 men, most of whom had been accustomed to the

habits of a city life. These men slept in tents and barns, and sometimes

in the open air during the usual colds of December and January; and yet

there were but two instances of sickness, and only one of death, in that

body of men in the course of nearly six weeks, in those winter months.

This extraordinary healthiness of so great a number of men under such

trying circumstances, can only be ascribed to the vigour infused into

the human body by the victory of Trenton having produced insensibility

to all the usual remote causes of diseases.

Militia officers and soldiers, who enjoyed good health during a

campaign, were often affected by fevers and other diseases, as soon

as they returned to their respective homes. I knew one instance of a

militia captain, who was seized with convulsions the first night he lay

on a feather bed, after sleeping several months on a mattrass, or upon

the ground. These affections of the body appeared to be produced only by

the sudden abstraction of that tone in the system which was excited by a

sense of danger, and the other invigorating objects of a military life.

The NOSTALGIA of Doctor Cullen, or the _home-sickness_, was a frequent

disease in the American army, more especially among the soldiers of

the New-England states. But this disease was suspended by the superior

action of the mind under the influence of the principles which governed

common soldiers in the American army. Of this General Gates furnished

me with a remarkable instance in 1776, soon after his return from the

command of a large body of regular troops and militia at Ticonderoga.

From the effects of the nostalgia, and the feebleness of the discipline,

which was exercised over the militia, desertions were very frequent and

numerous in his army, in the latter part of the campaign; and yet during

the _three weeks_ in which the general expected every hour an attack to

be made upon him by General Burgoyne, there was not a single desertion

from his army, which consisted at that time of 10,000 men.

The patience, firmness, and magnanimity with which the officers and

soldiers of the American army endured the complicated evils of hunger,

cold, and nakedness, can only be ascribed to an insensibility of body

produced by an uncommon tone of mind excited by the love of liberty and

their country.

Before I proceed to the second general division of this subject, I shall

take notice, that more instances of apoplexies occurred in the city of

Philadelphia, in the winter of 1774-5, than had been known in former

years. I should have hesitated in recording this fact, had I not found

the observation supported by a fact of the same kind, and produced

by a nearly similar cause, in the appendix to the practical works of

Doctor Baglivi, professor of physic and anatomy at Rome. After a very

wet season in the winter of 1694-5, he informs us, that "apoplexies

displayed their rage; and perhaps (adds our author) that some part of

this epidemic illness was owing to the universal grief and domestic

care, occasioned by all Europe being engaged in a war. All commerce

was disturbed, and all the avenues of peace blocked up, so that the

strongest heart could scarcely bear the thoughts of it." The winter of

1774-5 was a period of uncommon anxiety among the citizens of America.

Every countenance wore the marks of painful solicitude, for the event

of a petition to the throne of Britain, which was to determine whether

reconciliation, or a civil war, with all its terrible and distressing

consequences, were to take place. The apoplectic fit, which deprived the

world of the talents and virtues of Peyton Randolph, while he filled

the chair of congress, in 1775, appeared to be occasioned in part by

the pressure of the uncertainty of those great events upon his mind. To

the name of this illustrious patriot, several others might be added,

who were affected by the apoplexy in the same memorable year. At this

time a difference of opinion upon the subject of the contest with

Great-Britain, had scarcely taken place among the citizens of America.

II. The political events of the revolution produced different effects

upon the human body, through the medium of the mind, according as they

acted upon the friends or enemies of the revolution.

I shall first describe its effects upon the former class of citizens of

the United States.

Many persons, of infirm and delicate habits, were restored to perfect

health, by the change of place, or occupation, to which the war exposed

them. This was the case in a more especial manner with hysterical women,

who were much interested in the successful issue of the contest. The

same effects of a civil war upon the hysteria, were observed by Doctor

Cullen in Scotland, in the years 1745 and 1746. It may perhaps help to

extend our ideas of the influence of the passions upon diseases, to add,

that when either love, jealousy, grief, or even devotion, wholly engross

the female mind, they seldom fail, in like manner, to cure or to suspend

hysterical complaints.

An uncommon cheerfulness prevailed every where, among the friends of the

revolution. Defeats, and even the loss of relations and property, were

soon forgotten in the great objects of the war.

The population in the United States was more rapid from births during

the war, than it had ever been in the same number of years since the

settlement of the country.

I am disposed to ascribe this increase of births _chiefly_ to the

quantity and extensive circulation of money, and to the facility of

procuring the means of subsistence during the war, which favoured

marriages among the labouring part of the people[54]. But I have

sufficient documents to prove, that marriages were more fruitful than

in former years, and that a considerable number of unfruitful marriages

became fruitful during the war. In 1783, the year of the peace, there

were several children born of parents who had lived many years together

without issue.

[54] Wheat, which was sold before the war for seven shillings and

sixpence, was sold for several years _during_ the war for four,

and in some places for two and sixpence Pennsylvania currency

per bushel. Beggars of every description disappeared in the year

1776, and were seldom seen till near the close of the war.

Mr. Hume informs us, in his History of England, that some old people,

upon hearing the news of the restoration of Charles II, died suddenly

of joy. There was a time when I doubted the truth of this assertion;

but I am now disposed to believe it, from having heard of a similar

effect from an agreeable political event, in the course of the American

revolution. The door-keeper of congress, an aged man, died suddenly,

immediately after hearing of the capture of Lord Cornwallis' army. His

death was universally ascribed to a violent emotion of political joy.

This species of joy appears to be one of the strongest emotions that can

agitate the human mind.

Perhaps the influence of that ardour in trade and speculation, which

seized many of the friends of the revolution, and which was excited

by the fallacious nominal amount of the paper money, should rather be

considered as a disease, than as a passion. It unhinged the judgment,

deposed the moral faculty, and filled the imagination, in many people,

with airy and impracticable schemes of wealth and grandeur. Desultory

manners, and a peculiar species of extempore conduct, were among its

characteristic symptoms. It produced insensibility to cold, hunger, and

danger. The trading towns, and in some instances the extremities of the

United States, were frequently visited in a few hours or days by persons

affected by this disease; and hence "to travel with the speed of a

speculator," became a common saying in many parts of the country. This

species of insanity (if I may be allowed to call it by that name) did

not require the confinement of a bedlam to cure it, like the South-Sea

madness described by Doctor Mead. Its remedies were the depreciation of

the paper money, and the events of the peace.

The political events of the revolution produced upon its enemies very

different effects from those which have been mentioned.

The hypochondriasis of Doctor Cullen occurred, in many instances, in

persons of this description. In some of them, the terror and distress

of the revolution brought on a true melancholia[55]. The causes which

produced these diseases may be reduced to four heads. 1. The loss of

former power or influence in government. 2. The destruction of the

hierarchy of the English church in America. 3. The change in the habits

of diet, and company, and manners, produced by the annihilation of just

debts by means of depreciated paper money. And 4. The neglect, insults,

and oppression, to which the loyalists were exposed, from individuals,

and, in several instances, from the laws of some of the states.

[55] Insania partialis sine dyspepsia, of Doctor Cullen.

It was observed in South-Carolina, that several gentlemen who had

protected their estates by swearing allegiance to the British

government, died soon after the evacuation of Charleston by the British

army. Their deaths were ascribed to the neglect with which they were

treated by their ancient friends, who had adhered to the government of

the United States. The disease was called, by the common people, the

_protection fever_.

From the causes which produced this hypochondriasis, I have taken the

liberty of distinguishing it by the name of _revolutiana_.

In some cases, this disease was rendered fatal by exile and confinement;

and, in others, by those persons who were afflicted with it, seeking

relief from spiritous liquors.

The termination of the war by the peace in 1783, did not terminate the

American revolution. The minds of the citizens of the United States were

wholly unprepared for their new situation. The excess of the passion

for liberty, inflamed by the successful issue of the war, produced, in

many people, opinions and conduct which could not be removed by reason

nor restrained by government. For a while, they threatened to render

abortive the goodness of heaven to the United States, in delivering them

from the evils of slavery and war. The extensive influence which these

opinions had upon the understandings, passions, and morals of many of

the citizens of the United States, constituted a form of insanity, which

I shall take the liberty of distinguishing by the name of _anarchia_.

I hope no offence will be given by the freedom of any of these remarks.

An inquirer after philosophical truth should consider the passions of

men in the same light that he does the laws of matter or motion. The

friends and enemies of the American revolution must have been more, or

less than men, if they could have sustained the magnitude and rapidity

of the events that characterised it, without discovering some marks of

human weakness, both in body and mind. Perhaps these weaknesses were

permitted, that human nature might receive fresh honours in America,

by the contending parties (whether produced by the controversies about

independence or the national government) mutually forgiving each other,

and uniting in plans of general order, and happiness.

AN INQUIRY

INTO

THE RELATION OF

_TASTES AND ALIMENTS_

TO EACH OTHER,

AND

INTO THE INFLUENCE OF THIS RELATION

UPON

HEALTH AND PLEASURE.

In entering upon this subject, I feel like the clown, who, after several

unsuccessful attempts to play upon a violin, threw it hastily from him,

exclaiming at the same time, that "there was music in it," but that he

could not bring it out.

I shall endeavour, by a few brief remarks, to lay a foundation for more

successful inquiries upon this difficult subject.

Attraction and repulsion seem to be the active principles of the

universe. They pervade not only the greatest, but the minutest works

of nature. Salts, earths, inflammable bodies, metals, and vegetables,

have all their respective relations to each other. The order of these

relations is so uniform, that it has been ascribed by some philosophers

to a latent principle of intelligence pervading each of them.

Colours, odours, and sounds, have likewise their respective relations to

each other. They become agreeable and disagreeable, only in proportion

to the natural or unnatural combination which takes place between each

of their different species.

It is remarkable, that the number of original colours and notes in

music is exactly the same. All the variety in both, proceeds from the

difference of combination. An arbitrary combination of them is by no

means productive of pleasure. The relation which every colour and sound

bear to each other, was as immutably established at the creation, as

the order of the heavenly bodies, or as the relation of the objects of

chemistry to each other.

But this relation is not confined to colours and sounds alone. It

probably extends to the objects of human aliment. For example, bread and

meat, meat and salt, the alkalescent meats and acescent vegetables, all

harmonize with each other upon the tongue; while fish and flesh, butter

and raw onions, fish and milk, when combined, are all offensive to a

pure and healthy taste.

It would be agreeable to trace the analogy of sounds and tastes. They

have both their flats and their sharps. They are both improved by the

contrast of discords. Thus pepper, and other condiments (which are

disagreeable when taken by themselves) enhance the relish of many of our

aliments, and they are both delightful in proportion as they are simple

in their composition. To illustrate this analogy by more examples from

music, would lead us from the subject of the present inquiry.

It is observable that the tongue and the stomach, like instinct and

reason, are, by nature, in unison with each other. One of those organs

must always be disordered, when they disagree in a single article of

aliment. When they both unite in articles of diet that were originally

disagreeable, it is owing to a perversion in each of them, similar to

that which takes place in the human mind, when both the moral faculty

and the conscience lose their natural sensibility to virtue and vice.

Unfortunately for this part of science, the taste and the stomach are

so much perverted in infancy and childhood by heterogeneous aliment,

that it is difficult to tell what kinds, and mixtures of food are

natural, and what are artificial. It is true, the system possesses a

power of accommodating itself both to artificial food, and to the most

discordant mixtures of that which is natural; but may we not reasonably

suppose, that the system would preserve its natural strength and order

much longer, if no such violence had been offered to it?

If the relation of aliments to each other follows the analogy of the

objects of chemistry, then their union will be influenced by many

external circumstances, such as heat and cold, dilution, concentration,

rest, motion, and the addition of substances which promote unnatural,

or destroy natural mixtures. This idea enlarges the field of inquiry

before us, and leads us still further from facts and certainty upon this

subject, but at the same time it does not preclude us from the hope of

obtaining both; for every difficulty that arises out of this view of the

subject, may be removed by observation and experiment.

I come now to apply these remarks to health and pleasure. I shall select

only a few cases for this purpose; for if my principles be true, my

readers cannot avoid discovering many other illustrations of them.

1. When an article of diet is grateful to the taste, and afterwards

disagrees with the stomach, may it not be occasioned by some other kind

of food, or by some drink being taken into the stomach, which refuses to

unite with the offending article of diet?

2. May not the uneasiness which many persons feel after a moderate meal,

arise from its having consisted of articles of aliment which were not

related to each other?

3. May not the delicacy of stomach which sometimes occurs after the

fortieth or forty-fifth year of human life, be occasioned by nature

recovering her empire in the stomach, so as to require simplicity in

diet, or such articles only of aliment as are related? May not this be

the reason why most people, who have passed those periods of life, are

unable to retain or to digest fish and flesh at the same time, and why

they generally dine only upon one kind of food?

4. Is not the language of nature in favour of simplicity in diet,

discovered by the avidity with which the luxurious and intemperate often

seek relief from variety and satiety, by retreating to spring water for

drink, and to bread and milk for aliment?

5. May not the reason why plentiful meals of fish, venison, oysters,

beef, or mutton, when eaten alone, lie so easily in the stomach, and

digest so speedily, be occasioned by no other food being taken with

them? A pound, and even more, of the above articles, frequently oppress

the system much less than half the quantity of heterogeneous aliments.

6. Does not the facility with which a due mixture of vegetable and

animal food digests in the stomach, indicate the certainty of their

relation to each other?

7. May not the peculiar good effects of a diet wholly vegetable, or

animal, be occasioned by the more frequent and intimate relation of the

articles of the same kingdoms to each other? And may not this be the

reason why so few inconveniences are felt from the mixture of a variety

of vegetables in the stomach?

8. May not the numerous acute and chronic diseases of the rich and

luxurious, arise from heterogeneous aliments being distributed in a

_diffused_, instead of a _mixed_ state, through every part of the body?

9. May not the many cures which are ascribed to certain articles of

diet, be occasioned more by their being taken alone, than to any

medicinal quality inherent in them? A diet of oysters in one instance,

of strawberries in another, and of sugar of roses in many instances,

has cured violent and dangerous diseases of the breast[56]. Grapes,

according to Doctor Moore, when eaten in large quantities, have produced

the same salutary effect. A milk diet, persisted in for several

years, has cured the gout and epilepsy. I have seen many cases of

dyspepsia cured by a simple diet of beef and mutton, and have heard of

a well-attested case of a diet of veal alone having removed the same

disease. Squashes, and turnips likewise, when taken by themselves, have

cured that distressing complaint in the stomach. It has been removed

even by milk, when taken by itself in a moderate quantity[57]. The

further the body, and more especially the stomach, recede from health,

the more this simplicity of diet becomes necessary. The appetite in

these cases does not speak the language of uncorrupted nature. It

frequently calls for various and improper aliment; but this is the

effect of intemperance having produced an early breach between the taste

and the stomach.

[56] Vansweiten, 1209. 3.

[57] Medical Observations and Inquiries, vol. VI. p. 310, 319.

Perhaps the extraordinary cures of obstinate diseases which are

sometimes performed by persons not regularly educated in physic, may

be occasioned by a long and steady perseverance in the use of a single

article of the materia medica. Those chemical medicines which decompose

each other, are not the only substances which defeat the intention

of the prescriber. Galenical medicines, by combination, I believe,

frequently produce effects that are of a compound and contrary nature to

their original and simple qualities. This remark is capable of extensive

application, but I quit it as a digression from the subject of this

inquiry.

10. I wish it to be observed, that I have condemned the mixture of

different aliments in the stomach only in a few cases, and under certain

circumstances. It remains yet to determine by experiments, what changes

are produced upon aliments by heat, dilution, addition, concentration,

motion, rest, and the addition of uniting substances, before we can

decide upon the relation of aliments to each other, and the influence of

that relation upon health. The olla podrida of Spain is said to be a

pleasant and wholesome dish. It is probably rendered so, by a previous

tendency of all its ingredients to putrefaction, or by means of heat

producing a new arrangement, or additional new relations of all its

parts. I suspect heat to be a powerful agent in disposing heterogeneous

aliments to unite with each other; and hence the mixture of aliments is

probably less unhealthy in France and Spain, than in England, where so

much less fire is used in preparing them, than in the former countries.

As too great a mixture of glaring colours, which are related to each

other, becomes painful to the eye, so too great a mixture of related

aliments oppresses the stomach, and debilitates the powers of the

system. The original colours of the sky, and of the surface of the

globe, have ever been found the most permanently agreeable to the

eye. In like manner, I am disposed to believe that there are certain

simple aliments which correspond, in their sensible qualities, with the

intermediate colours of _blue_ and _green_, that are most permanently

agreeable to the tongue and stomach, and that every deviation from them,

is a departure from the simplicity of health and nature.

11. While nature seems to have limited us to simplicity in aliment, is

not this restriction abundantly compensated by the variety of tastes

which she allows us to impart to it, in order to diversify and increase

the pleasure of eating? It is remarkable that salt, sugar, mustard,

horse-radish, capers, and spices of all kinds, according to Mr. Gosse's

experiments, related by Abbé Spallanzani[58], all contribute not only to

render aliments savoury, but to promote their digestion.

[58] Dissertations, vol. I. p. 326.

12. When we consider, that part of the art of cookery consists in

rendering the taste of aliments agreeable, is it not probable that the

pleasure of eating might be increased beyond our present knowledge upon

that subject, by certain new arrangements or mixtures of the substances

which are used to impart a pleasant taste to our aliment?

13. Should philosophers ever stoop to this subject, may they not

discover and ascertain a table of the relations of sapid bodies to each

other, with the same accuracy that they have ascertained the relation of

the numerous objects of chemistry to each other?

14. When the tongue and stomach agree in the same kinds of aliment,

may not the increase of the pleasure of eating be accompanied with an

increase of health and prolongation of life?

15. Upon the pleasure of eating, I shall add the following remarks.

In order to render it truly exquisite, it is necessary that all the

senses, except that of taste, should be as _quiescent_ as possible.

Those persons mistake the nature of the appetite for food, who attempt

to whet it by accompanying a dinner by a band of music, or by connecting

the dining table, with an extensive and delightful prospect. The undue

excitement of one sense, always produces weakness in another. Even

conversation sometimes detracts from the pleasure of eating: hence

great feeders love to eat in silence, or alone; and hence the speech

of a passionate Frenchman, while dining in a talkative company, was

not so improper as might be at first imagined. "Hold your tongues

(said he); I cannot taste my dinner." I know a physician, who, upon

the same principle, always shuts his eyes, and requests silence in a

sick chamber, when he wishes to determine by the pulse the propriety

of blood-letting, in cases where its indication is doubtful. His

perceptions become more distinct, by confining his whole attention to

the sense of feeling.

It is impossible to mention the circumstance of the senses acting only

in succession to each other in the enjoyment of pleasure, without being

struck with the impartial goodness of Heaven, in placing the rich and

the poor so much upon a level in the pleasures of the table. Could the

numerous objects of pleasure, which are addressed to the ears and the

eyes, have been possessed at the same time with the pleasure of eating,

the rich would have commanded three times as much pleasure in that

enjoyment as the poor; but this is so far from being the case, that a

king has no advantage over a beggar, in eating the same kind of aliment.

THE

NEW METHOD OF INOCULATING

FOR THE

SMALL-POX.

DELIVERED IN A LECTURE IN THE UNIVERSITY OF PENNSYLVANIA,

ON THE 20TH OF FEBRUARY, 1781.

GENTLEMEN,

It must afford no small pleasure to a benevolent mind, in the midst of a

war which daily makes so much havoc with the human species, to reflect

that the small-pox, which once proved equally fatal to thousands, has

been checked in its career, and in a great degree subdued, by the

practice of INOCULATION.

It is foreign to my purpose to deliver to you the history of this

art, and to mark the various steps that have attended its progress to

its present state of improvement. We have yet to lament the want of

uniformity and of equal success in the practice of it among physicians.

A great number of pamphlets have been written upon the subject without

exhausting it. There is still ample room left for the man of genius to

exercise his talents for observation and reasoning upon it. The facts I

mean to lay before you are so inconsiderable, compared with what still

remain to be known upon this subject, that I have to request, when your

knowledge in it is completed, that you would bury my name in silence,

and forget that ever I ventured to lay a single stone in this part of

the fabric of science.

In treating upon this subject, I shall

I. Consider the proper subjects, and seasons for inoculation.

II. I shall describe the method of communicating the disease.

III. I shall consider the method of preparing the body for the small-pox.

IV. I shall mention the treatment proper during the eruptive fever. And,

V. Point out a few cautions that are necessary after the disease is

over.

I. Formerly there were great difficulties in the choice of subjects for

inoculation. But experience teaches us, that it may be practised in

every stage of life, and in almost every condition of the human body. In

infancy, the periods before and after dentition are to be preferred. But

we seldom see any great inconveniences from submitting to the general

necessity of inoculating children between the ages of three months, and

two years. Indeed we often see children cut three or four teeth during

the preparation and eruptive fever, without the least addition being

made to any of the troublesome symptoms which accompany the small-pox.

There is one inconvenience attending the choice of the first months

of infancy for inoculating, and that is, the matter often fails of

producing the disease in such young subjects. I have frequently failed

in two or three attempts to communicate it to children under four months

old, with the same matter that has succeeded in a dozen other patients,

inoculated at the same time. When the inoculation succeeds in such

tender subjects, they generally have less fever, and fewer pustules,

than are common in any future period of life.

Although a physician would prefer a patient in good health to any other

as a subject for inoculation, yet cases often occur in which it is

necessary to communicate the small-pox while the body is affected with

some other disease. I can with pleasure inform you, that the small-pox

is rendered so perfectly safe by inoculation, that there are few chronic

diseases which should be considered as obstacles in the way of it. I

have inoculated patients labouring under a tertian fever, obstructed

viscera, the hooping cough, the hypochondriasis, the asthma, the itch,

and other cutaneous diseases, and even pregnant women, with the same,

and, in some instances, with greater success, than persons in perfect

health. Doctor Cullen informs us, that he has seen inoculation succeed

in scrophulous patients. A physician in Jamaica informed me, that he

had inoculated negroes with success in the worst stage of the yaws. To

these facts I must add one more extraordinary than any that has been yet

mentioned: Doctor Brown, my late colleague in the care of the military

hospitals, informed me, that he had seen inoculation succeed in patients

who were seized, after the infection was communicated, with the hospital

fever. The preparation of the body should be accommodated to the disease

which affects it. Some physicians have thought the small-pox, received

in this way, was a remedy for other diseases; but my experience has not

confirmed this opinion: on the contrary, I am inclined to think that

no other change is produced by inoculation, than by the regimen and

medicines that are used to prepare the body for the small-pox. Nor does

the small-pox, during its continuance, afford any security against the

attacks of other diseases. I have seen the most alarming complication of

the small-pox and measles taken in _succession_ to each other, in the

same person.

The seasons commonly preferred for inoculation, in this country, are the

spring and fall. It may be practised with equal safety in the winter, a

due regard being had to the temperature of the air in the preparation of

the body.

The principal objection to inoculating in the summer months in this

climate, arises from the frequency of bilious diseases at that season,

to which the preparation necessary for the small-pox probably disposes

the body. This caution applies more directly to children, who, at a

certain age, are more subject than grown people to a disease in their

bowels in warm weather.

II. The methods of communicating the small-pox by inoculation, have

been different in different countries, and in the different æras of its

progress towards its present stage of improvement. The scab, dossel of

lint, and the thread impregnated with variolous matter, and bound up in

a gash in the arm, have been laid aside.

We are indebted to Mr. Sutton for the mode of communicating it by a

slight puncture with the point of a lancet, or needle, dipt in fresh

matter. As it is difficult sometimes to procure matter in a fresh

state, I have been led to use it with equal success by preserving

it on lint in a box, and moistening it with cold water just before

I used it. Matter may be kept in this way for a month, without

losing its infectious quality, provided it be not exposed to heat or

moisture. The former destroys its power of infecting as certainly

as the salt of tartar destroys the acidity of vinegar. Moisture, by

remaining long upon the matter, probably destroys its virulence, by

subjecting it to fermentation. The longer matter has been kept in

a general way, the longer the distance will be between the time of

communicating the disease, and the eruptive fever. It will be proper

always to yield to the prejudices of our patients in favour of matter

taken from persons who have but few pustules. But I am persuaded from

repeated observations, that the disease is no ways influenced by this

circumstance. I am satisfied likewise that there is no difference

between the effects of the matter, whether it be taken in its watery and

purulent state. The puncture should not be larger than is sufficient

to draw one drop of blood, but it should always be made by a _sharp_

lancet, for the sudden inflammation and suppuration, excited by a dull

lancet, sometimes throw off the matter, so as to prevent its infecting

the body[59]. No plaster or bandage should be applied over the puncture.

It should be made in the left arm of all subjects. The objections to

inoculating in the leg are too obvious to be mentioned. I have heard of

the disease being communicated by rubbing the dry skin with the matter.

My own observations upon this subject, give me reason to suspect the

facts that are contained in books relative to this mode of infecting

the body. I have bound large pieces of lint dipt in fresh matter for

twenty-four hours upon the arm, without producing the disease. A

practitioner of physic in New-Jersey informed me, that he once gave a

considerable quantity of fresh variolous matter in a dose of physic,

without infecting his patient. I suspect the matter that produces the

disease is of the same nature with certain poisons, which require to be

brought in contact with a wound or sore in the body, before they produce

their effects. I deliver this opinion with diffidence. The subject

stands in need of more experiments and investigation.

[59] I am disposed to believe that the external applications which are

used by the Indians for the cure of the bite of poisonous

snakes act only by exciting inflammation and suppuration, which

discharge the poison from the wound before it is absorbed. All

their external remedies are of a _stimulating_ nature.

III. I come now to consider the best method of preparing the body for

the small-pox. This must be done, 1st, by DIET, and 2dly, by MEDICINE.

The DIET should consist chiefly of vegetables. I have never seen any

inconvenience from the free use of milk, as a part of the preparative

diet. In some habits, where a morbid acid prevails in the stomach, we

may indulge our patients in a little weak flesh broth two or three times

a week with safety. A little salted meat may likewise be taken daily

in such cases. Tea, coffee, and even weak chocolate, with biscuit or

dry toast, may be used as usual, by persons accustomed to that kind

of aliment. Wine and spirits of all kinds should be withheld from our

patients, during the preparation. The more acescent their drinks are,

the better. It is unnecessary that this change in the diet should take

place till a day or two before the time of communicating the disease.

The system accommodates to a vegetable and low diet in the course of

three weeks or a month, so as to defeat in some measure the advantages

we expected from it. The good effects of it appear to depend in a

great degree upon the _suddenness_ with which we oblige our patients to

conform to it. For this reason, when we are called upon to inoculate

persons who have lived more than three or four weeks upon a low diet, we

should always direct them to live a few days upon animal food, before

we communicate the disease to them. By these means we may produce all

the good effects of the _sudden_ change in the diet I have already

mentioned. 2. The MEDICINES most commonly used to prepare the body

for the small-pox are antimony and mercury. The latter has had the

preference, and has been given in large quantities, under a notion of

its being a specific antidote to the variolous matter. Many objections

might be made to this opinion; I shall mention only three.

1. We often see the disease in a high degree, after the system is fully

impregnated with mercury.

2. We often see the same salutary effects of mercury, when given before

the disease is communicated to the body, that we perceive when it is

given after inoculation; in which case we are sure the mercury cannot

enter into the mixture with the variolous matter so as to destroy it.

3. If mercury acted specifically in destroying the variolous matter,

it would render every other part of the preparation unnecessary: but

this we know is not the case, for the neglect or improper use of the

vegetable diet or cool regimen is often attended with an extraordinary

number, or virulence of the small-pox, even in those cases where mercury

is given in the largest quantity.

The way in which mercury prepares the body for the small-pox, seems

to be by promoting the several excretions, particularly that by

perspiration, which, by diminishing the quantity of the fluids, and

weakening the tone of the solids, renders the system less liable to a

plentiful eruption of the small-pox. But I object to the use of this

medicine for the following reasons:

1. It effectually deprives us of all the benefits of the cool regimen;

for mercury, we know, always _disposes_ the system to take cold.

2. All the good effects of mercury may be produced by PURGES, which do

not subject the body to the above-mentioned inconvenience.

The PURGES may be suited to the constitutions, and in some cases, even

to the inclinations of our patients. I have seen jalap, rhubarb,

senna, manna, aloes, soluble tartar, glauber and Epsom salts, and the

butter-nut pill, all given with equal success. The quantity should be

sufficient to procure three or four stools every day. A little magnesia

should always be mixed with rhubarb and jalap in preparing children.

It will be sufficient for the mothers and nurses of infants to conform

strictly to the vegetable diet. I have never seen any advantages from

giving them even a single dose of physic.

It is hardly necessary to observe, that the quality, dose, and number of

purges are to be determined by the age, sex, and habits of our patients.

A constitution enfeebled by a previous disease forbids the use of

purges, and requires medicines of a restorative kind. Patients afflicted

with cutaneous diseases bear larger and more frequent doses of physic,

than are indicated in more healthy subjects.

In adult subjects of a plethoric habit, blood-letting is very useful on

the third or fourth day after inoculation. We are not to suppose, that

every fat person labours under a plethora. A moderate degree of fat is

so far from rendering the disease more violent, especially in children,

that I think I have generally found such subjects have the small-pox

more favourably than others.

Moderate exercise in the open air should be used during the preparation.

But hard labour, and every thing that promotes sweat or fatigue, as also

the extremes of heat and cold, should be avoided.

IV. We come now to consider the treatment of the body during the

eruptive fever. On the eighth day after inoculation our patients are

_generally_ seized with the common symptoms of fever. Sometimes this

fever appears on the sixth and seventh day after inoculation. But when

it is irregular, it is often delayed till the ninth and tenth days. I

have seen many instances of it on the fourteenth, a few on the fifteenth

and sixteenth, and _one_ case in which it did not come on till the

eighteenth day after the infection was communicated to the body[60]. The

place where the puncture was made with the lancet, or needle, generally

serves as a harbinger of the approaching fever. A slight inflammation

appears about it, and a pock rises up in the centre. But this remark is

liable to some objections. I have seen _four_ instances in which the

fever came on at the expected time, and the disease went through all

its stages with the greatest regularity, and yet there was no sign of

an inflammation or pock near the spot where the puncture was made: even

the puncture itself became invisible. On the other hand, we sometimes

see an inflammation and pock on the arm appear on the eighth and ninth

days, without any fever accompanying them. Some physicians suppose that

this inflammation and solitary pock are sufficient to constitute the

disease; but repeated experience has taught me to be very cautious in

relying upon these equivocal marks. It is true, I have sometimes seen

patients secured against the small-pox, both in the natural way and by

inoculation, where these marks have appeared; but I have as often seen

such patients seized afterwards with the small-pox in the natural way,

to the great distress of families, and mortification of physicians.

Upon this account, I make it a constant practice to advise a second

or third inoculation, where a fever and eruption have been wanting. As

the absence of these symptoms is probably occasioned by the weakness or

age of the variolous matter, or the too high state of preparation of

the body, we should always guard against both, by making the puncture

the second time with _fresh_ matter, by subjecting our patients to a

_less_ abstemious diet, and by giving fewer doses of physic. I have

heard it remarked, that if a slight redness and a small pimple appeared

on the arm on the third day after inoculation, it was a sign the matter

had infected the whole constitution. I acknowledge I have often seen

a greater degree of redness on the third than on the second day after

inoculation, but I have not been able to establish a diagnostic mark

from it; for I have seen the disease produced on the usual days where

the redness has appeared on the second day, and in some cases where it

has not appeared until the eruptive fever.

[60] Since the publication of the first edition of this lecture, I have

heard of two cases, in one of which the fever did not come on

till the twentieth, and in the other till the twenty-first day

after the infection was communicated to the body. In some of

these tedious cases, I have seen an inflammation and suppuration

on the punctured part of the arm on the eighth day without any

fever. Perhaps in these cases the inflammation and suppuration

are only cuticular, and that the small-pox is taken from the

matter which is formed by them.

I am led here unwillingly to discuss the old question, Is it possible

to have the small-pox in the natural way after inoculation?--In

many of the cases supposed to be the small-pox from inoculation, it

is probable the matter has been taken from the chicken-pox, which

resembles the small-pox in many of its peculiarities, but in none

more than that of leaving pits or marks on the skin. But there are

certainly cases where there are the most irrefragable proofs of the

infection implanted by inoculation being of a variolous nature, where

the disease has been afterwards taken in the natural way. In these

cases I would suppose the variolous matter produced only a topical or

cuticular disease. We see something analogous to this in nurses who

attend patients in the small-pox. But further, this topical or cuticular

infection may be produced by art in persons who have had the small-pox

in the natural way. Some years ago, I made a puncture on my left hand

with a lancet moistened with variolous matter. On the eighth day an

inflammation appeared on the place, accompanied by an efflorescence

in the neighbourhood of it, which extended about two inches in every

direction from the spot where the puncture was made. On the eleventh

day I was surprised to find two pocks (if I may venture to call them

such), the one on the outside of the fourth finger of my left hand,

and the other on my forehead. They remained there for several days,

but without filling with matter, and then dropped off, rather in the

form of a soft wart, than of a common scab. Doctor Way of Wilmington

repeated the same experiment upon himself, but with an issue to his

curiosity more extraordinary than that I have just now related. On the

eighth day after he had made a puncture on his hand, a pock appeared

on the spot, which in the usual time filled with matter, from which he

inoculated several children, who sickened at the usual time, and went

through all the common stages and symptoms of the small-pox. It would

seem from these facts, that it is necessary the small-pox should produce

some impression upon the _whole_ system, in order to render it ever

afterwards incapable of receiving an impression of a similar nature. A

fever and an eruption therefore seem necessary for this purpose. As the

inflammation of the arm on the eighth day is a sign of the _topical_

and cuticular infection, so an eruption (though ever so small) seems to

be the only certain sign of the infection of the _whole_ system. The

eruption is the more decisive in its report, in proportion as it comes

out and goes off in the usual manner of the small-pox in the natural

way. In those cases where patients have been secured against a second

attack of the disease, when there have been no _obvious_ fever or

_visible_ eruption, I think I have observed an unusual inflammation, and

a copious and long continued discharge of matter from the arm. Perhaps

this may serve as an outlet of the matter, which in other cases produces

the fever and eruption. I am the more disposed to embrace this opinion,

from the testimony which several authors have left us of the effects

of ulcers in securing the body from the infection of the plague. The

effects of issues are still more to our purpose. We observe a plentiful

discharge of matter from them every time the body is exposed to cold,

and the febrile effects of it upon the system are thereby frequently

obviated. How far a ratio exists between the degrees of inflammation

and the discharge of matter from the arm, and the degrees of fever and

eruption, must be determined by future and very accurate observations.

If it should appear, that there are the least inflammation and smallest

discharge, where there have been the highest fever and most copious

eruption; and, on the contrary, if it should appear that there are

the greatest inflammation and discharge, where there have been the

least fever and smallest eruption, I must beg leave to add, without

attempting in this place to explain the reasons of it, that the remark,

if generally true, is liable to some exceptions. But the subject is

involved in darkness; I shall be satisfied if I have brought you within

sight of the promised land. Your own ingenuity, like another Jewish

leader, must conduct you thither.

The indications in the treatment of the body during the eruptive fever

are,

I. To regulate the degree of fever.

II. To mitigate troublesome and alarming symptoms.

The fever which produces the eruption is generally of the inflammatory

kind. It sometimes, therefore, comes on with the symptoms of great heat,

preceded with chilliness, and determination to the head and breast, and

a full hard pulse. The remedies proper in this case are,

1. Blood-letting. The quantity to be drawn must be regulated by the

violence of the symptoms, the constitution, habits, and even country of

the patient, and by the season of the year. I have never found more than

one bleeding, to the quantity of twelve or fourteen ounces, necessary

in any stage or degree of the eruptive fever of the small-pox by

inoculation.

2. Cool air is of the utmost consequence in the eruptive fever. The

use of this remedy in fevers marks an æra, not only in the management

of the small-pox, but in medicine. The degrees of cold should always

be increased in proportion to the violence of the fever. Stove-rooms,

so common in this country, should be carefully avoided. The more we

oblige our patients to sit up and walk in the open air, the better. Even

in those cases where they languish most for the bed, they should be

encouraged rather to lie upon, than _under_ the bed-clothes. Children

should be stript of flannel petticoats that come in contact with their

skins; and even clouts should be laid aside, if possible without great

inconvenience, and at any rate they should be often removed. Great and

obvious as the advantages of cold air appear to be in the eruptive

fever, it has sometimes been used to an excess that has done mischief.

There are few cases where a degree of cold below fifty of _Fahrenheit's_

thermometer is necessary in this stage of the small-pox. When it has

been used below this, or where patients have been exposed to a damp

atmosphere some degrees above it, I have heard of inflammations of an

alarming nature being produced in the throat and breast.

3. The bowels, more especially of children, should be kept open with

gentle laxatives. And,

4. Cool subacid drinks should be plentifully used until the eruption be

completed.

Sometimes the small-pox comes on with a fever the reverse of that which

we have described. The heat is inconsiderable, the pulse is weak, and

scarcely quicker than ordinary, and the patient complains of but

slight pains in the back and head. Here the treatment should be widely

different from that which has been mentioned when the fever is of the

inflammatory kind. Bleeding in this case is hurtful, and even cool air

must be admitted with caution. The business of the physician in this

case is to excite a gentle action in the sanguiferous system, in order

to produce the degree of fever which is necessary to the eruption of the

pock. For this purpose he may recommend the use of warm drinks, and even

of a warm bed with advantage. If the eruption delay beyond the third

day, with all the circumstances of debility that have been mentioned, I

have frequently ordered my patients to eat a few ounces of animal food,

and to drink a glass or two of wine, with the most desirable success.

The effects of this indulgence are most obvious where the weakness

of the fever and the delay of the eruption in children, have made it

necessary to allow it to mothers and nurses.

The small-pox by inoculation so seldom comes on with the symptoms of

what is called a malignant fever, that little need be said of the

treatment proper in such cases. I shall only observe, that the cold

regimen in the highest degree, promises more success in these cases than

in any others. I have repeatedly been told, that when the small-pox

appears confluent among the Africans, it is a common practice for

mothers to rub their children all over with pepper, and plunge them

immediately afterwards into a spring of cold water. This, they say,

destroys a great part of the pock, and disposes the remainder to a

kindly suppuration. From the success that has attended the use of the

cold bath in malignant fevers in some parts of Europe[61], I am disposed

to believe in the efficacy of the African remedy.

[61] In a dissertation entitled "_Epidemia verna quæ Wratislaviam,

Anno. 1737 afflixit_," published in the appendix to the Acta Nat.

Curios. Vol. X. it appears, that washing the body all over with

cold water in putrid fevers, attended with great debility, was

attended with success at _Breslaw_ in _Silesia_. The practice has

since been adopted, we are told, by several of the neighbouring

countries. CULLEN'S FIRST LINES OF THE PRACTICE OF PHYSIC.

The fever generally lasts three days, and the eruption continues for a

similar length of time, counting the last day of the fever, as the first

day of the eruption. But this remark is liable to many exceptions. We

sometimes observe the eruption to begin on the first, and often on the

second day of the fever; and we sometimes meet with cases in which a

second eruption comes on after the fever has abated for several days,

and the first eruption considerably advanced in its progress towards

a complete suppuration. This is often occasioned by the application of

excessive cold or heat to the body, or by a sudden and premature use of

stimulating drinks, or animal food.

I come now to treat of the best method of mitigating troublesome and

alarming symptoms.

The only _alarming_ symptom is convulsions, to which children are

subject during the time of dentition. These have been less frequent,

since the liberal and judicious use of cool air in the eruptive fever

than formerly. They are often relieved by putting the feet in warm

water. But a more effectual and speedy method of curing them, is to

expose our patients suddenly to the open air. The colder the air the

quicker relief it affords in these cases. To prevent the return of the

fits, as well as to allay any disagreeable and troublesome startings, a

few drops of laudanum should be given. They generally yield in a little

while to this excellent remedy.

The next symptom which demands the aid of our art, is the inflammation

and sore on the arm. Poultices of all kinds should be laid aside, as

tending to increase the inflammation and sore. Instead of these, the

part affected should be washed three or four times a day with cold

water[62]. This application is not only agreeable to our patients, but

soon checks the progress of the inflammation, and disposes the sore to

heal about the time the eruption is completed. The eyes should likewise

be washed frequently with cold water, to secure them from pustules and

inflammation. With respect to those alarming or troublesome symptoms

which occur in those cases where the pocks are numerous, or confluent,

they happen so seldom in inoculation, that they do not come properly

under our notice in this place. They are moreover fully discussed by

Doctors Boerhaave, Huxham, Hillary, and other practical writers.

[62] Where the inflammation on the arm has been so considerable as not

to yield immediately to the application of cold water, I have

used the vegeto-mineral water with advantage.

V. I come now, in the last place, to deliver a few directions that are

necessary after the eruption and suppuration are over.

It is well known that eruptions of an obstinate nature sometimes follow

the small-pox. These I believe are often occasioned by a too _sudden_

and speedy use of animal food. To guard against these disagreeable

consequences of inoculation, it is of the utmost importance to enjoin a

cautious and _gradual_ return to the free use of an animal diet; and at

the same time it will be necessary to give our patients a dose or two of

purging physic.

Thus, gentlemen, have I delivered to you a short history of the new

method of inoculating for the small-pox. I am aware that prejudices are

entertained against some parts of it by physicians of the most ancient

name and character among us. I have witnessed the effects of the old and

new methods of preparing the body upon many thousand patients, and I am

satisfied, not only from my own observations, but from the experience

of gentlemen upon whose judgments I rely more than upon my own, that

the new method is by far the safest and most successful. Added to this,

I can assure my pupils, that I have never known a single instance of a

patient, prepared and treated in the manner I have described, that ever

had an abscess after the small-pox, or even such an inflammation or sore

upon the arm as required the application of a poultice.

AN INQUIRY

INTO THE

_EFFECTS OF ARDENT SPIRITS_

UPON THE

HUMAN BODY AND MIND.

WITH

AN ACCOUNT OF THE MEANS OF PREVENTING,

AND OF THE

_REMEDIES FOR CURING THEM_.

PART I.

By ardent spirits, I mean those liquors only which are obtained by

distillation from fermented substances of any kind. To their effects

upon the bodies and minds of men, the following inquiry shall be

exclusively confined. Fermented liquors contain so little spirit, and

that so intimately combined with other matters, that they can seldom

be drunken in sufficient quantities to produce intoxication, and its

subsequent effects, without exciting a disrelish to their taste, or

pain, from their distending the stomach. They are moreover, when taken

in a moderate quantity, generally innocent, and often have a friendly

influence upon health and life.

The effects of ardent spirits divide themselves into such as are of

a prompt, and such as are of a chronic nature. The former discover

themselves in drunkenness, and the latter, in a numerous train of

diseases and vices of the body and mind.

I. I shall begin by briefly describing their prompt, or immediate

effects, in a fit of drunkenness.

This odious disease (for by that name it should be called) appears with

more or less of the following symptoms, and most commonly in the order

in which I shall enumerate them.

1. Unusual garrulity.

2. Unusual silence.

3. Captiousness, and a disposition to quarrel.

4. Uncommon good humour, and an insipid simpering, or laugh.

5. Profane swearing, and cursing.

6. A disclosure of their own, or other people's secrets.

7. A rude disposition to tell those persons in company, whom they know,

their faults.

8. Certain immodest actions. I am sorry to say, this sign of the first

stage of drunkenness, sometimes appears in women, who, when sober, are

uniformly remarkable for chaste and decent manners.

9. A clipping of words.

10. Fighting; a black eye, or a swelled nose, often mark this grade of

drunkenness.

11. Certain extravagant acts which indicate a temporary fit of madness.

These are singing, hallooing, roaring, imitating the noises of brute

animals, jumping, tearing off clothes, dancing naked, breaking glasses

and china, and dashing other articles of household furniture upon

the ground, or floor. After a while the paroxysm of drunkenness is

completely formed. The face now becomes flushed; the eyes project, and

are somewhat watery; winking is less frequent than is natural; the under

lip is protruded; the head inclines a little to one shoulder; the jaw

falls; belchings and hiccup take place; the limbs totter; the whole

body staggers. The unfortunate subject of this history next falls on

his seat; he looks around him with a vacant countenance, and mutters

inarticulate sounds to himself. He attempts to rise and walk; in this

attempt, he falls upon his side, from which he gradually turns upon

his back. He now closes his eyes, and falls into a profound sleep,

frequently attended with snoring, and profuse sweats, and sometimes with

such a relaxation of the muscles which confine the bladder and the lower

bowels, as to produce a symptom which delicacy forbids me to mention. In

this condition, he often lies from ten, twelve, and twenty-four hours,

to two, three, four, and five days, an object of pity and disgust to his

family and friends. His recovery from this fit of intoxication is marked

with several peculiar appearances. He opens his eyes, and closes them

again; he gapes and stretches his limbs; he then coughs and pukes; his

voice is hoarse; he rises with difficulty, and staggers to a chair; his

eyes resemble balls of fire; his hands tremble; he loathes the sight of

food; he calls for a glass of spirits to compose his stomach; now and

then he emits a deep-fetched sigh, or groan, from a transient twinge of

conscience, but he more frequently scolds, and curses every thing around

him. In this state of languor and stupidity he remains for two or three

days, before he is able to resume his former habits of business and

conversation.

Pythagoras we are told maintained that the souls of men after death,

expiated the crimes committed by them in this world, by animating

certain brute animals; and that the souls of those animals in their

turns, entered into men, and carried with them all their peculiar

qualities and vices. This doctrine of one of the wisest and best of the

Greek philosophers, was probably intended only to convey a lively idea

of the changes which are induced in the body and mind of man by a fit of

drunkenness. In folly, it causes him to resemble a calf; in stupidity,

an ass; in roaring, a mad bull; in quarrelling, and fighting, a dog;

in cruelty, a tiger; in fetor, a skunk; in filthiness, a hog; and in

obscenity, a he-goat.

It belongs to the history of drunkenness to remark, that its paroxysms

occur, like the paroxysms of many diseases, at certain periods, and

after longer or shorter intervals. They often begin with annual, and

gradually increase in their frequency, until they appear in quarterly,

monthly, weekly, and quotidian or daily periods. Finally they afford

scarcely any marks of remission, either during the day or the night.

There was a citizen of Philadelphia, many years ago, in whom drunkenness

appeared in this protracted form. In speaking of him to one of his

neighbours, I said,

"Does he not _sometimes_ get drunk?" "You mean," said his neighbour, "is

he not _sometimes_ sober?"

It is further remarkable, that drunkenness resembles certain hereditary,

family, and contagious diseases. I have once known it to descend from a

father to four out of five of his children. I have seen three, and once

four brothers who were born of sober ancestors, affected by it, and I

have heard of its spreading through a whole family composed of members

not originally related to each other. These facts are important, and

should not be overlooked by parents, in deciding upon the matrimonial

connections of their children.

Let us next attend to the chronic effects of ardent spirits upon the

body and mind. In the body, they dispose to every form of acute disease;

they moreover _excite_ fevers in persons predisposed to them, from other

causes. This has been remarked in all the yellow fevers which have

visited the cities of the United States. Hard drinkers seldom escape,

and rarely recover from them. The following diseases are the usual

consequences of the habitual use of ardent spirits, viz.

1. A decay of appetite, sickness at stomach, and a puking of bile, or a

discharge of a frothy and viscid phlegm by hawking, in the morning.

2. Obstructions of the liver. The fable of Prometheus, on whose liver a

vulture was said to prey constantly, as a punishment for his stealing

fire from heaven, was intended to illustrate the painful effects of

ardent spirits upon that organ of the body.

3. Jaundice and dropsy of the belly and limbs, and finally of every

cavity in the body. A swelling in the feet and legs is so characteristic

a mark of habits of intemperance, that the merchants in Charleston, I

have been told, cease to trust the planters of South-Carolina, as soon

as they perceive it. They very naturally conclude industry and virtue

to be extinct in that man, in whom that symptom of disease has been

produced by the intemperate use of distilled spirits.

4. Hoarseness, and a husky cough, which often terminate in consumption,

and sometimes in an acute and fatal disease of the lungs.

5. Diabetes, that is, a frequent and weakening discharge of pale, or

sweetish urine.

6. Redness and eruptions on different parts of the body. They generally

begin on the nose, and after gradually extending all over the face,

sometimes descend to the limbs in the form of leprosy. They have been

called "rum-buds," when they appear in the face. In persons who have

occasionally survived these effects of ardent spirits on the skin, the

face after a while becomes bloated, and its redness is succeeded by a

death-like paleness. Thus the same fire which produces a red colour in

iron, when urged to a more intense degree, produces what has been called

a white heat.

7. A fetid breath, composed of every thing that is offensive in putrid

animal matter.

8. Frequent and disgusting belchings. Dr. Haller relates the case of a

notorious drunkard having been suddenly destroyed, in consequence of the

vapour discharged from his stomach by belching, accidentally taking fire

by coming in contact with the flame of a candle.

9. Epilepsy.

10. Gout, in all its various forms of swelled limbs, colic, palsy, and

apoplexy.

Lastly, 11. Madness. The late Dr. Waters, while he acted as house

pupil and apothecary of the Pennsylvania hospital, assured me, that in

one-third of the patients confined by this terrible disease, it had been

induced by ardent spirits.

Most of the diseases which have been enumerated are of a mortal nature.

They are more certainly induced, and terminate more speedily in death,

when spirits are taken in such quantities, and at such times, as to

produce frequent intoxication: but it may serve to remove an error with

which some intemperate people console themselves, to remark, that ardent

spirits often bring on fatal diseases without producing drunkenness. I

have known many persons destroyed by them, who were never completely

intoxicated during the whole course of their lives. The solitary

instances of longevity which are now and then met with in hard drinkers,

no more disprove the deadly effects of ardent spirits, than the solitary

instances of recoveries from apparent death by drowning, prove that

there is no danger to life from a human body lying an hour or two under

water.

The body after its death, from the use of distilled spirits, exhibits

by dissection certain appearances which are of a peculiar nature. The

fibres of the stomach and bowels are contracted; abscesses, gangrene,

and schirri are found in the viscera; the bronchial vessels are

contracted; the blood-vessels and tendons, in many parts of the body,

are more or less ossified; and even the hair of the head possesses a

crispness which renders it less valuable to wig-makers than the hair of

sober people.

Not less destructive are the effects of ardent spirits upon the human

mind. They impair the memory, debilitate the understanding, and pervert

the moral faculties. It was probably from observing these effects of

intemperance in drinking, upon the mind, that a law was formerly passed

in Spain, which excluded drunkards from being witnesses in a court of

justice. But the demoralizing effects of distilled spirits do not stop

here. They produce not only falsehood, but fraud, theft, uncleanliness,

and murder. Like the demoniac mentioned in the New Testament, their name

is "legion," for they convey into the soul, a host of vices and crimes.

A more affecting spectacle cannot be exhibited, than a person into whom

this infernal spirit, generated by habits of intemperance, has entered.

It is more or less affecting, according to the station the person fills

in a family, or in society, who is possessed by it. Is he a husband? How

deep the anguish which rends the bosom of his wife! Is she a wife? Who

can measure the shame and aversion which she excites in her husband! Is

he the father, or is she the mother of a family of children? See their

averted looks from their parent, and their blushing looks at each other!

Is he a magistrate? or has he been chosen to fill a high and respectable

station in the councils of his country? What humiliating fears of

corruption in the administration of the laws, and of the subversion of

public order and happiness, appear in the countenances of all who see

him! Is he a minister of the gospel? Here language fails me.----If

angels weep,--it is at such a sight.

In pointing out the evils produced by ardent spirits, let us not pass

by their effects upon the estates of the persons who are addicted to

them. Are they inhabitants of cities? Behold their houses stripped

gradually of their furniture, and pawned, or sold by a constable, to

pay tavern debts! See their names upon record in the dockets of every

court, and whole pages of newspapers filled with advertisements of

their estates for public sale! Are they inhabitants of country places?

Behold their houses with shattered windows! their barns with leaky

roofs! their gardens over-run with weeds! their fields with broken

fences! their hogs without yokes! their sheep without wool! their cattle

and horses without fat! and their children filthy, and half clad,

without manners, principles, and morals! This picture of agricultural

wretchedness is seldom of long duration. The farms and property thus

neglected, and depreciated, are seized and sold for the benefit of a

group of creditors. The children that were born with the prospect of

inheriting them, are bound out to service in the neighbourhood; while

their parents, the unworthy authors of their misfortunes, ramble into

new and distant settlements, alternately fed on their way by the hand of

charity, or a little casual labour.

Thus we see poverty and misery, crimes and infamy, diseases and death,

are all the natural and usual consequences of the intemperate use of

ardent spirits.

I have classed death among the consequences of hard drinking. But it

is not death from the immediate hand of the Deity, nor from any of the

instruments of it which were created by him. It is death from SUICIDE.

Yes! thou poor degraded creature, who art daily lifting the poisoned

bowl to thy lips, cease to avoid the unhallowed ground in which the

self-murderer is interred, and wonder no longer that the sun should

shine, and the rain fall, and the grass look green upon his grave.

Thou art perpetrating gradually, by the use of ardent spirits, what

he has effected suddenly, by opium, or a halter. Considering how many

circumstances, from a sudden gust of passion, or from derangement, may

palliate his guilt, or that (unlike yours) it was not preceded and

accompanied by any other crime, it is probable his condemnation will be

less than yours at the day of judgment.

I shall now take notice of the occasions and circumstances which are

supposed to render the use of ardent spirits necessary, and endeavour

to show that the arguments in favour of their use in such cases are

founded in error, and that, in each of them, ardent spirits, instead of

affording strength to the body, increase the evils they are intended to

relieve.

1. They are said to be necessary in very cold weather. This is far from

being true; for the temporary warmth they produce, is always succeeded

by a greater disposition in the body to be affected by cold. Warm

dresses, a plentiful meal just before exposure to the cold, and eating

occasionally a little gingerbread, or any other cordial food, is a much

more durable method of preserving the heat of the body in cold weather.

2. They are said to be necessary in very warm weather. Experience proves

that they increase instead of lessening the effects of heat upon the

body, and thereby dispose to diseases of all kinds. Even in the warm

climate of the West-Indies, Dr. Bell asserts this to be true. "Rum

(says this author) whether used habitually, moderately, or in excessive

quantities, in the West-Indies, always diminishes the strength of the

body, and renders men more susceptible of disease, and unfit for any

service in which vigour or activity is required[63]." As well might

we throw oil into a house, the roof of which was on fire, in order to

prevent the flames from extending to its inside, as pour ardent spirits

into the stomach, to lessen the effects of a hot sun upon the skin.

[63] Inquiry into the causes which produce, and the means of preventing

diseases among British officers, soldiers, and others in the

West-Indies.

3. Nor do ardent spirits lessen the effects of hard labour upon the

body. Look at the horse: with every muscle of his body swelled from

morning till night in the plough, or a team, does he make signs for

a draught of toddy or a glass of spirits, to enable him to cleave the

ground, or to climb a hill? No; he requires nothing but cool water,

and substantial food. There is no nourishment in ardent spirits. The

strength they produce in labour is of a transient nature, and is always

followed by a sense of weakness and fatigue.

But are there no conditions of the human body in which ardent spirits

may be given? I answer, there are. 1st. When the body has been suddenly

exhausted of its strength, and a disposition to faintness has been

induced. Here a few spoonsful, or a wine-glassful of spirits, with

or without water, may be administered with safety and advantage. In

this case we comply strictly with the advice of Solomon, who restricts

the use of "strong drink" only "to him who is ready to perish." 2dly.

When the body has been exposed for a long time to wet weather, more

especially if it be combined with cold. Here a moderate quantity of

spirits is not only safe, but highly proper to obviate debility, and to

prevent a fever. They will more certainly have those salutary effects,

if the feet are at the same time bathed with them, or a half pint of

them poured into the shoes or boots. These I believe are the only two

cases in which distilled spirits are useful or necessary to persons in

health.

Medical Inquiries and Observations, Vol. 1 The Second Edition, Revised and Enlarged by the Author · 第 1 / 3 章