The terms on which this licence was granted are remarkable.

_UNDER THE SUPERINTENDENCE OF THE SOCIETY FOR THE DIFFUSION OF USEFUL

KNOWLEDGE._

THE

GALLERY OF PORTRAITS:

WITH

MEMOIRS.

VOLUME VI.

LONDON:

CHARLES KNIGHT, 22, LUDGATE-STREET.

1836.

[PRICE ONE GUINEA, BOUND IN CLOTH.]

LONDON:

PRINTED BY WILLIAM CLOWES AND SONS,

Duke-Street, Lambeth.

------------------------------------------------------------------------

PORTRAITS AND BIOGRAPHIES

CONTAINED IN THIS VOLUME.

Page.

1. Raleigh 1

2. Jenner 11

3. Maskelyne 20

4. Hobbes 25

5. Raphael 30

6. John Knox 40

7. Adam Smith 49

8. Calvin 55

9. Lord Mansfield 62

10. Bradley 69

11. Melancthon 75

12. William Pitt 84

13. Wesley 93

14. Dr. Cartwright 102

15. Porson 108

16. Wiclif 113

17. Cortez 122

18. Leibnitz 132

19. Ximenes 137

20. Addison 147

21. Bramante 156

22. Madame de Stael 161

23. Palladio 172

24. Queen Elizabeth 177

[Illustration:

_Engraved by Posselwhite._

RALEIGH.

_From a Picture in the Collection of the Duchess of Dorset._

Under the Superintendance of the Society for the Diffusion of Useful

Knowledge.

_London, Published by Charles Knight, Ludgate Street._

]

[Illustration]

RALEIGH.

Very little is known concerning the youth of Sir Walter Raleigh. He was

a younger son, descended of an ancient family, and was born at a farm

called Hayes, near the mouth of the river Otter, in Devonshire, in the

year 1552. He went to Oriel College, Oxford, at an early age, and gained

high praise for the quickness and precocity of his talents. In 1569 he

began his military career in the civil wars of France, as a volunteer in

the Protestant cause. It is conjectured that he remained in France for

more than six years, and returned to England in 1576. Soon after, he

repaired to the Netherlands, and served as a volunteer against the

Spaniards. In such schools, and under such leaders as Coligni and the

Prince of Orange, Raleigh’s natural aptitude for political and military

science received the best nurture: but he was soon drawn from the war in

Holland by a pursuit which had captivated his imagination from an early

age—the prosecution of discovery in the New World. In conjunction with

his half-brother, Sir Humphrey Gilbert, a man of courage and ability,

and a skilful sailor, he made an unsuccessful attempt to establish a

colony in North America. Returning home in 1579, he immediately entered

the Queen’s army in Ireland, and served with good esteem for personal

courage and professional skill, until the suppression of the rebellion

in that country. He owed his introduction to court, and the personal

favour of Elizabeth, as is traditionally reported, to a fortunate and

well-improved accident, which is too familiar to need repetition here.

It is probable, however, that his name and talents were not unknown, for

we find him employed almost immediately in certain matters of diplomacy.

Among the cares and pleasures of a courtier’s life, Raleigh preserved

his zeal for American discovery. He applied his own resources to the

fitting out of another expedition in 1583, under command of Sir Humphrey

Gilbert, which proved more unfortunate than the former one: two out of

five vessels returned home in consequence of sickness, and two were

wrecked, including that in which the admiral sailed; and the only result

of the enterprise was the taking possession of Newfoundland in the name

of England. Still Raleigh’s desire for American adventure was not

damped. The Continent northward of the Gulf of Florida was at this time

unknown. But Raleigh, upon careful study of the best authorities, had

concluded that there was good reason for believing that a considerable

tract of land did exist in that quarter; and with the assent of the

Queen in council, from whom he obtained letters patent, granting to

himself and his heirs, under certain reservations, property in such

countries as he should discover, with a right to provide for their

protection and administration, he fitted out two ships, which sailed in

April, 1584. The first land which they made was an island named Okakoke,

running parallel to the coast of North Carolina. They were well received

by the natives, and returned to England in the following autumn highly

pleased. Nor was less satisfaction felt by Raleigh, or even by the

Queen, who conferred on him the honour of knighthood, a title which was

then in high esteem, inasmuch as it was bestowed by that wise princess

with a most frugal and just discrimination. She also gave him a very

lucrative mark of favour, in the shape of a patent for licensing the

selling of wine throughout the kingdom; and she directed that the new

country, in allusion to herself, should be called Virginia. Raleigh did

not think it politic, perhaps was not allowed, to quit the court to take

charge in person of his undertaking; and those to whom he intrusted the

difficult task of directing the infant colony appear to have been

unequal to their office. It is not necessary to pursue the history of an

enterprise which proved unsuccessful, and in which Sir Walter personally

bore no share. He showed his earnestness by fitting out several

expeditions, which must have been a heavy drain upon his fortune. But he

is said to have derived immense wealth from prizes captured from the

Spaniards; and we may here observe that the lavish magnificence in

dress, especially in jewels, for which Raleigh was remarkable, even in

the gorgeous court of Elizabeth (his state dress is said to have been

enriched with jewels to the value of £60,000), may be considered less as

an extravagance, than as a safe and portable investment of treasure. A

mind less active might have found employment more than enough in the

variety of occupations which pressed upon it at home. He possessed a

large estate, granted out of forfeited lands, in Ireland; but this was

always a source rather of expense than of profit, until, in 1601, he

sold it to the Earl of Cork. He was Seneschal of the Duchies of Cornwall

and Exeter, and held the wardenship of the Stannaries; and in 1586, as

well as formerly in 1584, we find that he possessed a seat in

parliament. In 1587, the formidable preparation of the Spanish Armada

withdrew the mind of Raleigh, as of all Englishmen, from objects of

minor importance, to the defence of their country. He was a member of

the council of war directed to prepare a general scheme of defence, and

held the office of Lieutenant-General of Cornwall, in addition to the

charge of the Isle of Portland: but as on this occasion he possessed no

naval command, he was not actively engaged in the destruction of that

mighty armament. In 1589 he served as a volunteer in the expedition of

Norris and Drake to Portugal, of which some account has been given in

the life of the latter. Nor were his labours unrewarded even in that

unfortunate enterprise; for he captured several prizes, and received the

present of a gold chain from the Queen, in testimony of her approbation

of his conduct.

Soon after these events, Raleigh retired to his Irish property, being

driven from court, according to some authorities, by the enmity of the

Earl of Essex, then a young man just rising into favour. He there

renewed a former intimacy with the poet Spenser, who, like himself, had

been rewarded with a grant of land out of forfeited estates, and then

resided at Kilcolman Castle. Spenser has celebrated the return of his

friend in the beautiful pastoral, ‘Colin Clout’s come home again;’ and

in that, and various passages of his works, has made honourable mention

of the highly poetic spirit which enabled the ‘Shepherd of the Ocean,’

as he is there denominated, to appreciate the merit of the ‘Fairy

Queen,’ and led him to promote the publication of it by every means in

his power. The loss of Raleigh’s court-favour, if such there were, could

not have been of long duration on this occasion. But he incurred more

serious displeasure in consequence of a private marriage contracted with

Elizabeth Throgmorton, one of the Queen’s maids of honour, a lady of

beauty and accomplishments, who proved her worth and fidelity in the

long train of misfortunes which beset the latter years of Raleigh’s

life. In consequence of this intrigue, he was committed to the Tower.

One or two amusing anecdotes are related of the devices which he

employed to obtain forgiveness, by working on that vanity which was the

Queen’s chief foible. He succeeded in appeasing his indignant mistress

so far as to procure his release; and about the same time, in 1594, she

granted to him the valuable manor of Sherborne, in Dorsetshire: but

though she requited his services, she still forbade his appearance at

court, where he now held the office of Captain of the Yeomen of the

Guard. Raleigh was peculiarly fitted to adorn a court by his imposing

person, the graceful magnificence of his taste and habits, the elegance

of his manners, and the interest of his conversation. These

accomplishments were sure passports to the favour of Elizabeth; and he

improved to the utmost the constant opportunities of intercourse with

her which his post afforded, insomuch that, except the Earls of

Leicester and Essex, no one ever seems to have stood higher in her

graces. But Elizabeth’s jealousy on the subject of her favourites’

marriages is well known, and her anger was lasting, in proportion to the

value which she set on the incense of Raleigh’s flattery. He retired, on

his disgrace, to his new estate, in the improvement and embellishment of

which he felt great interest. But though deeply alive to the beauties of

nature, he had been too long trained to a life of ambition and adventure

to rest contented in the tranquil routine of a country life; and during

this period of seclusion, he again turned his thoughts to his favourite

subject of American adventure, and laid the scheme of his first

expedition to Guiana, in search of the celebrated El Dorado, the fabled

seat of inexhaustible wealth. Having fitted out, with the assistance of

other private persons, a considerable fleet, Raleigh sailed from

Plymouth, February 6, 1595. He left his ships in the mouth of the river

Orinoco, and sailed 400 miles into the interior in boats. It is to be

recorded to his honour, that he treated the Indians with great kindness;

which, contrasted with the savage conduct of the Spaniards, raised so

friendly a feeling towards him, that for years his return was eagerly

expected, and at length was hailed with delight. The hardships of the

undertaking, and the natural advantages of the country which he

explored, are eloquently described in his own account of the ‘Discovery

of Guiana.’ But the setting in of the rainy season rendered it necessary

to return, without having reached the promised land of wealth; and

Raleigh reaped no other fruit of his adventure than a certain quantity

of geographical knowledge, and a full conviction of the importance of

colonizing and taking possession of the newly-discovered region. This

continued through life to be his favourite scheme; but neither Elizabeth

nor her successor could be induced to view it in the same favourable

light.

On reaching England, he found the Queen still unappeased; nor was he

suffered to appear at court: and he complains in pathetic terms of the

cold return with which his perils and losses were requited. But he was

invested with a high command in the expedition of 1596, by which the

Spanish fleet was destroyed in the harbour of Cadiz; and to his judgment

and temper in overruling the faulty schemes proposed by others the

success of that enterprise was chiefly due. Indeed his services were

perhaps too important, and too justly appreciated by the public, for his

own interests: for the great and general praise bestowed on him on this

occasion tended to confirm a jealousy of long standing on the part of

the commander-in-chief, the Earl of Essex; and it was probably owing to

that favourite’s influence, that Raleigh was still forbidden the Queen’s

presence. Essex, and the Secretary of State, Sir Robert Cecil, regarded

each other with mutual distrust and dislike. Cecil and Raleigh were

connected by ties of common interest, and, as the latter supposed, of

friendship. Still Raleigh found the interest of the minister too weak to

serve his purpose, while the interest of the favourite was employed

against him; and, as the only method of effecting his own restoration to

the Queen’s favour, he undertook to work a reconciliation between these

two powerful rivals. In this he succeeded, to the great admiration of

all spectators; and the fruit of his policy was seen in his re-admission

to the execution of his official duties at court, June 1, 1597. In the

following August he was appointed Rear Admiral in the expedition called

the Island Voyage, of which Essex held the chief command. The slight

successes which were obtained were again due to the military talents of

Raleigh; the main objects of the voyage were lost through the Earl’s

inexperience.

From this time to the death of the Queen, Raleigh enjoyed an

uninterrupted course of favour. The ancient enmity between Essex and

himself was indeed renewed, and that with increased rancour; but the

indiscretions of the favourite had greatly weakened his influence.

Raleigh and Cecil spared no pains to undermine him, and were in fact the

chief workers of his ruin. This is perhaps the most unamiable passage in

Raleigh’s life; and the only excuse to be pleaded for him is, the

determined enmity of that unfortunate nobleman. This fault, however,

brought a slow but severe punishment with it; for the death of Essex

dissolved the tie which held together Cecil and himself. Neither could

be content to act second to the other; and Raleigh’s high reputation,

and versatile as well as profound abilities, might well alarm the

secretary for his own supremacy. The latter took the surest way of

establishing his power prospectively. Elizabeth was now old: Cecil took

no steps to diminish the high esteem in which she held Sir Walter

Raleigh, but he secretly laboured to prejudice her successor against

him, and he succeeded to his wish. Very soon after the accession of

James I., Raleigh’s post of captain of the guard was taken from him; and

his patent of wines was revoked, though not without a nominal

compensation being made. To complete his ruin, it was contrived to

involve him in a charge of treason. Most writers have concurred in

speaking of this passage of history as inexplicable: it is the opinion

of the last historian of Raleigh, Mr. Tytler, that he has found

sufficient evidence for regarding the whole plot as a device of Cecil,

and he has supported this opinion by cogent arguments. Lord Cobham, a

violent and ambitious but weak man, had engaged in private dealings with

the Spanish ambassador, which brought him under the suspicion of the

government. By a device of Cecil’s (we here follow the account of Mr.

Tytler) he was induced, in a fit of anger, and in the belief that

Raleigh had given information against him, to accuse Sir Walter himself

of being privy to a conspiracy against the government. This charge

Cobham retracted, confirmed, and retracted again, behaving in so

equivocal a manner, that no reliance whatever can be placed on any of

his assertions. But as the King was afraid of Raleigh as much as the

secretary hated him, this vague charge, unsupported by other evidence,

was made sufficient to commit him to the Tower; and, after being plied

with private examinations, in which nothing criminal could be elicited,

he was brought to trial, November 17, 1603. For an account of that

memorable scene we shall refer to Mr. Jardine’s ‘Criminal Trials,’ vol.

i. It is reported to have been said by one of the judges who presided

over it, on his death-bed, that “the justice of England had never been

so degraded and injured as by the condemnation of Sir Walter Raleigh.”

The behaviour of the victim himself was the object of universal

admiration, for the tempered mixture of patience and noble spirit with

which he bore the oppressive measure dealt to him. He had before been

unpopular; but it was recorded by an eye-witness that “he behaved

himself so worthily, so wisely, and so temperately, that in half a day

the mind of all the company was changed from the extremest hate to the

extremest pity.”

The sentence of death thus unfairly and disgracefully obtained was not

immediately carried into execution. James was not satisfied with the

evidence adduced on the trial; and believing at the same time that

Raleigh had been plotting against him, he set his royal wit to dive into

the mystery. Of the singular scene which our British Solomon devised it

is not necessary to speak, since Raleigh was not an actor in it. But as

no more evidence could be obtained against him even by the King’s

sagacity, he was reprieved, and remanded to the Tower, where the next

twelve years of his life were spent in confinement. Fortunately, he had

never ceased to cultivate literature with a zeal not often found in the

soldier and politician, and he now beguiled the tedium of his lot by an

entire devotion to those studies which before had only served to

diversify his more active and engrossing pursuits. Of his poetical

talents we have already made short mention: to the end of life he

continued the practice of pouring out his mind in verse, and there are

several well-known and beautiful pieces expressive of his feelings in

prison, and in the anticipation of immediate death, especially ‘The

Lie,’ and the beautiful little poem called ‘The Pilgrimage.’ He also

possessed a strong turn for mathematics, and studied them with much

success in the society and under the guidance of his friend Thomas

Hariot, one of the most accomplished mathematicians of the age.

Chemistry was another favourite pursuit in which, according to the

standard of his contemporaries, he made great progress. But the most

important occupation of his imprisonment was the composition of his

‘History of the World.’ Notwithstanding the quaintness of the style and

the discursive manner in which the subject is treated, it is impossible

to read this volume without admiring the wonderful extent of the

author’s reading, not only in history, but in philosophy, theology, and

even the ponderous and untempting stores of Rabbinical learning. Many of

the chapters relate to subjects which few persons would expect to find

in a history of the world; yet these will often be found among the most

interesting and characteristic portions of the book; and its deep

learning is relieved and set off by passages of genuine eloquence, which

display to the best advantage the author’s rich imagination and grasp of

mind. The work extends from the Creation to the end of the second

Macedonian war. Raleigh meant to bring it down to modern times; but the

untimely death of Henry Prince of Wales, for whose use it was composed,

deprived him of the spirit to proceed with so laborious an undertaking.

He enjoyed the confidence of that generous youth in a remarkable degree,

and maintained a close correspondence with him on civil, military, and

naval subjects. Several discourses on these topics, addressed to the

Prince, will be found in the editions of Raleigh’s works. Henry repaid

these services with sincere friendship and admiration; and we may

presume that his adviser looked forward to that friendship, not only for

a cessation of misfortune, but for a more brilliant period of favour and

power than he had yet enjoyed. Fortunately, however, this calamity was

preceded by the death of his arch-enemy, Cecil; and through the

mediation of the Duke of Buckingham, employed in consideration of

1500_l._ paid to his uncles, Sir William, Sir John, and Sir Edward

Villiers, Raleigh was released from the Tower in March, 1615; and

obtained permission to follow up his long-cherished scheme of

establishing a colony in Guiana and working a gold mine, of which he had

ascertained the existence and situation.

The terms on which this licence was granted are remarkable. He was not

pardoned, but merely let loose on the engagement of his friends, the

Earls of Arundel and Pembroke, that he should return to England. Neither

did James contribute to the expense of the undertaking, though it was

stipulated that he was to receive a fifth part of the bullion imported.

The necessary funds were provided out of the wreck of Raleigh’s fortune

(his estate of Sherborne had been forfeited) and by those private

adventurers who were willing to risk something in reliance on his

experience and judgment. A fleet of fourteen sail was thus provided, and

Raleigh, by letters under the privy seal, was appointed

commander-in-chief and governor of the intended colony. He relied, it is

said, on the full powers granted him by this commission as necessarily

including a remission of all past offences, and therefore neglected to

sue out a formal pardon, which at this period probably would hardly have

been denied him. The results of this disastrous voyage must be shortly

given. Raleigh sailed March 28, 1617, and reached the coast of Guiana in

November following. Being himself disabled by sickness from proceeding

farther, he dispatched a party to the mine under the command of Captain

Keymis, an officer who had served in the former voyage to Guiana. But

during the interval which had elapsed since Raleigh’s first discovery of

that country, the Spaniards had extended their settlements into it, and

in particular had built a town called Santa Thome, in the immediate

neighbourhood of the mine in question. James, with his usual duplicity,

while he authorised the expedition, revealed every particular connected

with it to the Spanish ambassador. The English, therefore, were expected

in the Orinoco, and preparation had been made for repelling them by

force. Keymis and his men were unexpectedly attacked by the garrison of

Santa Thome, and a sharp contest ensued, in which the English gained the

advantage, and burnt the town. In this action Raleigh’s eldest son was

killed. The Spaniards still occupied the passes to the mine, and after

an unsuccessful attempt to dislodge them, Keymis abandoned the

enterprize, and returned to the ships. Raleigh’s correspondence

expresses in affecting terms his grief and indignation at this double

misfortune; the loss of a brave and promising son, and the destruction

of the hopes which he had founded on this long-cherished adventure. On

his return to England, he found himself marked out for a victim to

appease the resentment of the Spanish court, to which he had long been

an object of fear and hatred. He quietly surrendered himself to Sir

Lewis Stukeley, who was sent to Plymouth to arrest him, and commenced

the journey to London under his charge. But his mind fluctuated between

the desire to confront his enemies, and a sense of the hopelessness of

obtaining justice, and he was at last entrapped by the artifices of the

emissaries of government who surrounded him into an attempt to escape,

in which he was arrested and committed to close custody in the Tower.

Here his conversation and correspondence were narrowly watched, in the

hopes that a treasonable understanding with the French government, from

which he had received the offer of an asylum in France, might be

established against him. His conduct abroad had already been closely

scrutinized, in the hope of finding some act of piracy, or unauthorized

aggression against Spain, for which he might be brought to trial. Both

these hopes failing, and his death, in compliment to Spain, being

resolved on, it was determined to carry into effect the sentence passed

fifteen years before, from which he had never been legally released; and

a warrant was accordingly issued to the judges, requiring them to order

execution. The case was a novel one, and threw that learned body into

some perplexity. They determined, however, that after so long an

interval execution could not be granted without allowing the prisoner

the opportunity of pleading against it; and Raleigh was therefore

brought to the bar of the Court of King’s Bench, October 28, 1618. The

record of his conviction having been read, he was asked whether he could

urge any thing why the sentence should not be carried into effect. He

insisted on the nature of his late commission, and on that plea being

overruled, submitted with his usual calmness and dignity. The execution,

with indecent haste, was ordered to take place on the following morning.

In this last stage of life, his greatness of mind shone with even more

than its usual lustre. Calm, and fearless without bravado, his behaviour

and speech expressed the piety and resignation of a Christian with the

habitual coolness of one who has braved death too often to shrink at its

approach. The accounts of his deportment on the scaffold effectually

refute the charges of irreligion and atheism which some writers have

brought against him, unless we make up our minds to believe him an

accomplished hypocrite. He spoke at considerable length, and his dying

words have been faithfully reported. They contain a denial of all the

serious offences laid to his charge, and express his forgiveness of

those even who had betrayed him under the mask of friendship. After

delivering this address and spending some time in prayer, he laid his

head on the block, and breathing a short private prayer, gave the signal

to the executioner. Not being immediately obeyed, he partially raised

his head, and said, “What dost thou fear? Strike, man!” and underwent

the fatal blow without shrinking or alteration of position. He died in

his sixty-sixth year.

Raleigh sat in several parliaments, and took an active part in the

business of the house. His speeches, preserved in the Journals, are said

by Mr. Tytler to be remarkable for an originality and freedom of thought

far in advance of the time. His expression was varied and animated, and

his powers of conversation remarkable. His person was dignified and

handsome, and he excelled in bodily accomplishments and martial

exercises. He was very fond of paintings, and of music; and, in

literature as in art, he possessed a cultivated and correct taste. He

was one of those rare men who seem qualified to excel in all pursuits

alike; and his talents were set off by an extraordinary laboriousness,

and capacity of application. As a navigator, soldier, statesman, and

historian, his name is intimately and honourably linked with one of the

most brilliant periods of British history.

The works of Oldys, Birch, Cayley, Mrs. Thompson, and Mr. Tytler, may be

consulted concerning this remarkable person. The life of the last-named

gentleman, published in the ‘Edinburgh Cabinet Library,’ is the most

recent; and the industry of the author has enabled him to gain a clue to

some points which before had been imperfectly understood. A list of

Raleigh’s numerous works is given in the ‘Biographia Britannica.’ They

will be found collected in eight volumes, in the Oxford edition of 1829.

Several of his MSS. are preserved in the British Museum.

[Illustration: [Sir Walter Raleigh in the Tower.]]

[Illustration:

_Engraved by E. Scriven._

JENNER.

_From a Print engraved and coloured by J. R. Smith in the possession

of the late John Ring Esq^r._

Under the Superintendance of the Society for the Diffusion of Useful

Knowledge.

_London, Published by Charles Knight, Ludgate Street._

]

[Illustration]

JENNER.

Edward, the third son of the Rev. Stephen Jenner, was born May 17, 1749,

in the vicarage-house of Berkeley in Gloucestershire, of which parish

his father, a man of independent fortune, and of a family long

established and esteemed in that neighbourhood, was incumbent. At the

death of that parent in 1754, the care of Edward Jenner’s education

devolved upon his eldest brother, Stephen, who succeeded to the living

of Berkeley, and faithfully and affectionately discharged the duties of

a father towards him.

He began at a very early age to give tokens of that fondness and

aptitude for the study of natural history, which first directed the

choice of his profession; and afterwards led him, by steps which may be

easily traced, to the discovery of a method of securing the constitution

against the small-pox, by a remedy so mild as to be scarcely an

inconvenience, yet so effectual as almost to have extinguished that

disease in some countries where it has been energetically used.

Having finished his school education and fixed upon a profession, Jenner

was apprenticed at the usual age to Mr. Ludlow, a surgeon practising at

Sodbury near Bristol; and in 1770, when nearly twenty-one, he came to

London, and put himself under the tuition of John Hunter, in whose house

he lived for two years, as much in the capacity of a friend as in that

of a pupil, with great advantage to his professional studies. The

intimacy between these two eminent men was very close and cordial, and

subsisted till Hunter’s sudden death in 1793. It is attested by many

letters from Mr. Hunter, which Jenner carefully preserved; his own were

probably destroyed with the rest of Hunter’s papers by the late Sir

Everard Home. Their correspondence relates chiefly to facts and

experiments in natural history.

The success with which Jenner had already pursued his studies, and the

respect entertained for his talents by his illustrious instructor at a

period when their intercourse was yet in its infancy, may be gathered

from his being selected in 1771, on the recommendation of Mr. Hunter, to

arrange the collections in natural history which had been made by Sir

Joseph Banks in his voyage round the world with Captain Cook, then just

completed. Jenner acquitted himself so well of this charge, that he was

offered, though little more than twenty-two years of age, the situation

of naturalist to the second expedition under the command of Captain

Cook, which sailed in 1772. This was a flattering proposal to so young a

man, and consonant to Jenner’s ruling tastes; nevertheless he declined

it. It is fortunate for mankind that he chose the laborious seclusion of

a country practice in preference to aiming at distinction and wealth;

for in no other sphere could he have found opportunities of pursuing his

discovery of vaccination through all the perplexities in which his early

researches into that subject involved him. Indeed, it is probable that

considerations of this kind, independently of his fondness for a country

life, had their weight with him in the choice; for the idea had already

taken strong hold of his naturally sanguine feelings and quick

apprehension, that he was furnished with a clue which might lead him to

a result of the highest importance to mankind.

It may be added here that a few years after this time he declined a very

lucrative situation in India, as well as a much more tempting proposal

from Mr. Hunter, in 1775, to join him in a project for establishing in

London a school of natural history, including medicine, of which Jenner

was to undertake the anatomical department.

Having determined to settle in the country, and being amply provided

with the requisite knowledge, Jenner established himself as a general

practitioner at Berkeley. Here he speedily acquired a profitable and

extensive practice; so much so, indeed, that finding his health giving

way, he was obliged to limit himself to the practice of medicine alone;

for which purpose he purchased, as it was then customary, the degree of

doctor at St. Andrew’s in 1792.

But he not only attained at an early age to a high degree of

professional reputation, but won the affectionate esteem of all with

whom he associated. It is related of him that his friends were in the

habit of joining in his daily professional rides, often of considerable

extent, for the sake of his agreeable and instructive conversation; and

that when any of them were ill, he would sometimes make their houses the

head-quarters of his practice for the time being, and remain in close

attendance upon them till their recovery.

Music, the lighter kinds of literature, both as a reader and

occasionally as an author, and the innocent recreations of society,

which no one enjoyed more keenly than himself, were the means by which

Jenner lightened the burden of his professional labours; but his chief

amusement was natural history, including geology, a science then in its

infancy, for the study of which his position in the vale of Gloucester

afforded ample opportunity, the neighbourhood abounding with fossil

remains, and exhibiting a great variety of terrestrial structure.

Towards subjects of this nature he was led, not only by his original

bias, but by his correspondence with Hunter, Banks, and Parry.

In 1778 he formed a medical society, which held its periodical meetings

at Rodborough, for the purpose of communicating professional information

and promoting a friendly feeling among the members. In furtherance of

these objects, Jenner contributed several important and original papers,

the substance of which is now embodied in medical science, without his

property in them being generally known. Among these were essays on the

nature and causes of Angina Pectoris, on a peculiar disease of the heart

occurring in acute rheumatism, and on several of the more severe

affections of the eye. He also belonged to another medical society,

meeting at Alveston near Bristol, to the members of which, who were men

of congenial dispositions with his own, he was personally much attached.

Upon one topic, however, they did not agree; for it is said that he was

in the habit of enlarging so frequently upon his favourite speculation

of the cow-pox, that the subject was at length proscribed, and he was

jestingly forbidden to renew it on pain of expulsion. This club was for

many years a source of much enjoyment and advantage to him, and we may

suppose that he was a very principal contributor to the diversion of the

other members; for it ceased to exist in 1789, when other objects began

to engross the time that he could spare from his practice. In March of

the previous year, at the age of thirty-seven, he married Miss Catharine

Kingscote, by whom he had several children. The choice appears to have

been a very fortunate one for his domestic happiness.

In 1786 he had communicated to Mr. Hunter, in the form of an essay, the

result of several years’ careful observation of the singular habits of

the cuckoo, till then a mystery to naturalists. It was presented by Mr.

Hunter to the Royal Society, and was printed entire in their

Transactions in 1789, having been returned to Jenner in the mean time,

in order that he might record some additional facts which he had

ascertained. This tract has been considered as a very masterly

performance, and was the occasion of the author being elected to the

fellowship of the Royal Society. It is not a little remarkable that Mr.

Hunter, like Jenner’s friends at Alveston, thought so doubtfully of his

views on the subject of vaccination, that he cautioned him against

publishing them, lest they should interfere with the fame he had

acquired in the learned world by his ‘Essay on the Cuckoo.’ But the

event proved that the caution, though well meant, was unnecessary.

Jenner was not more disposed than his gifted master to admit any

conclusion on merely collateral grounds, that might be put to the test

of experiment. This, however, was too new and important a matter to be

lightly or prematurely hazarded; and Jenner waited long and patiently

for an opportunity of thus testing his opinions, losing in the mean time

no occasion of collecting additional information. The idea, thus

watchfully and laboriously improved, was first excited in his mind while

he was an apprentice at Sodbury, by a remark accidentally dropped by a

young countrywoman in his master’s surgery, who, overhearing a

conversation about the small-pox, observed that she had no fear of

catching that disease as she had taken the _cow-pox_. Jenner, who was

always alive to any subject connected with natural history, was induced

to make more particular inquiries into this complaint, of which he had

never heard before; and the answers he received were such as to suggest

the probability of substituting it with advantage for the inoculated

small-pox. Of this theory he never lost sight till he established it on

the clearest evidence, and with it his unrivalled claim to the perpetual

gratitude of mankind.

The cow-pox is a disease of the eruptive kind, which is sometimes

extensively prevalent among cattle in large dairy countries where they

are herded together in numbers, but often disappears for a long time

together. Though commonly mild, it is occasionally so severe as to

terminate fatally; and it is believed, on strong grounds, to have been

at different times even pestilential among them, and as such, to have

been mentioned by various writers on rural economy, ancient and modern,

as well as in medical and other histories. It is generally, however, a

very mild disorder, appearing on the udder of the cow, at first in the

form of vesicles much resembling those of small-pox; and it is

sometimes, as in the instance which first attracted the attention of

Jenner, communicated to the hands of milkers. In such cases, an eruption

of similar vesicles takes place on the hands and arms, not without much

swelling and inflammation, and occasionally with fever and disturbance

of the health for some days. It has never been known to prove fatal when

thus communicated, or to have left any unpleasant effects behind it,

except a few indented marks in the situation occupied by the pustules.

It is not communicable, like small-pox in the human subject, by the

effluvia; but the matter, or lymph as it is called, contained in the

vesicles, must be actually inserted under the skin, or applied to a raw

or an absorbing surface. But the most important of its peculiarities is

the security it affords against the infection of small-pox. This

property was well known among the agricultural classes in the grazing

districts before the time of Jenner, and it has been stated that

individuals among them had turned their knowledge of it to account for

the protection of their families, by inoculating them with the vaccine

disease. But this circumstance, alleged on very scanty evidence by those

who were opposed to Jenner’s claims, cannot lessen the merit of his

independent discovery, of which each step was communicated in succession

to a numerous circle of medical friends, and is recorded in the most

authentic form. His reputation is, on the other hand, enhanced by the

fact that, although the immunity conferred by the casual disease in

milkers had frequently come under the notice of medical men from their

failing in such persons to produce the small-pox by inoculation, yet the

idea of introducing the disease of an animal into the human frame was so

little in consonance with any former practice, that Jenner was the first

among his brethren to conjecture that cow-pox, as the milder disease,

might advantageously supersede the inoculated small-pox; and that, as

the latter is rendered less virulent by inoculation, so the former

introduced in the same way might be milder than the casual complaint,

and yet retain its protecting power. He had even communicated this

conjecture to Hunter, himself no mean innovator in medicine, so early as

the year 1770; and Mr. Hunter was for many years in the habit of

mentioning it in his public lectures coupled with Jenner’s name: but the

proposed substitution was so distasteful, or appeared of such

questionable propriety, that it obtained no favourable notice till it

was forced by the inventor on the public attention, thirty years after

it had first attracted his own.

It would be interesting to enter into a detail of the progress of

Jenner’s discovery and of its introduction into general use, as well as

to show its inestimable value to society by a reference to statistical

facts. This, however, can only be done here in a very cursory manner.

The way in which the idea was first suggested to him has been already

mentioned. After his return to Berkeley from London, he pursued the

subject with great patience and sagacity for many years. In the course

of these preliminary inquiries he found reason to believe that of

several kinds of vesicular disease in the cow, but one had the property

of securing from the small-pox, and that one exclusively, or at least

with the greatest certainty, in its first stage. He also ascertained

that the horse is subject to an eruption of similar vesicles, apparently

arising without infection, and popularly known by the name of the

_grease_. The matter issuing from these is sometimes conveyed to the cow

by milkers engaged in farriery; and Jenner conceived it to be the

original and only source of cow-pox among the herds. The opinion is not

generally held at present to its full extent; but experiments by himself

and others since the publication of his Inquiry have proved a fact much

disputed at the time, that he was right in believing the diseases to be

identical, whatever may be their origin.

It may be mentioned as a curious circumstance, that the first lymph

transmitted in an active state to British India in 1802 by Dr. De Carro

of Vienna, long the only source of vaccination in that country, had been

furnished to him by Dr. Sacco of Milan, from genuine vesicles produced

by direct inoculation from the horse, without passing through the cow;

an intervention which, till about that period, Jenner had continued to

think essential to the production of the true disease in man.

In addition to these and other curious results, laboriously collected

during a period of twenty-six years, Dr. Jenner at length arrived at a

rational conviction of the safety of the experiment he meditated, from

observing the invariable harmlessness of the disease when casually

taken: he determined therefore to put his long-cherished idea to the

trial on the first opportunity.

This offered on the 14th of May, 1796, the anniversary of which is still

kept as a festival at Berlin. On that day he inoculated a boy of the

name of Phipps in the arm, from a pustule on the hand of a young woman

who was infected by her master’s cows. The boy went favourably through

the disease. On the 1st of July he was inoculated for the small-pox,

and, as Jenner had predicted, without effect.

The feelings of the sanguine philanthropist may be conceived. They

cannot be better described than they have been by himself in the

following terms. “While the vaccine discovery was progressive, the joy I

felt at the prospect before me of being the instrument destined to take

away from the world one of its greatest calamities, blended with the

fond hope of enjoying independence and domestic peace and happiness, was

often so excessive, that in pursuing my favourite subject among the

meadows, I have sometimes found myself in a reverie. It is pleasant to

me to recollect that these reflections always ended in devout

acknowledgments to that Being from whom this and all other mercies

flow.”

During the next two years many other equally successful trials were

made; and at length the discovery was published to the world in June,

1798, in a quarto pamphlet of seventy pages, which had been previously

subjected to the most rigorous criticism and revision by a few chosen

friends who met for that purpose at the house of Thomas Westfaling,

Esq., at Rudhall, near Ross. It is entitled ‘An Inquiry into the Causes

and Effects of the Variolæ Vaccinæ; a disease discovered in some of the

Western Counties of England, particularly Gloucestershire, and known by

the name of the Cow-pox.’ The pamphlet is enriched with the detail of

sixteen cases of the casual, and seven of the inoculated disease, the

latter including the case of one of the author’s sons; and with coloured

drawings of the appearances in both.

The style of this pamphlet, as well as of others which succeeded it from

Jenner’s pen in the course of a few years, is remarkably modest, and

admirable in all respects, which probably contributed much to the early

favour it received. The facts were such as to defy contradiction, and

the conclusions so just and mature, that the experience of nearly forty

years has been able to add little more than its seal of confirmation to

them. The few errors that have been detected relate chiefly to the

degree of protection afforded by the cow-pox, which Jenner affirmed to

be perfect: it is now however believed to be incomplete, perhaps in

three instances out of every hundred; that small proportionate number

passing, in general after the lapse of some years, through a very mild

and modified small-pox, in which the per-centage of fatal cases is

certainly not more, and probably much less, than five; being not more

than three in 2000 of all vaccinated persons, while the rate of

mortality even in inoculated small-pox is one in fifty, or forty in

2000. It should be borne in mind that small-pox itself sometimes occurs

a second time even in a severe and fatal form, as in the case of Louis

XV. Some constitutional peculiarity is probably the occasion of both

these anomalies; and this supposition will also account for the

often-observed fact, that small-pox after vaccination commonly affects

several members of the same family almost simultaneously, thus giving an

appearance of failure in a proportion much greater than the truth.

Another position advanced by Jenner in this pamphlet is too remarkable

to be passed over. After stating his belief that the cow-pox originates

from the horse in the way already mentioned, he proceeds to suggest that

the small-pox may have been itself originally morbid matter of the same

kind, aggravated into a malignant and contagious form by accidental

circumstances. But this opinion, though plausible, is not considered by

any means as established.

Favourably as his work was received, the author, who had come to London

partly to superintend the publication, was unable to obtain an

opportunity of displaying the disease in that city, which had been the

chief object of his visit; and returned, much disappointed, to

Cheltenham, where he now frequently resided, in the middle of July. He

left, however, some vaccine lymph with Mr. Cline, who was the first

surgeon in London that ventured to make a trial of it. The complete

success of the experiment, which was publicly performed, so strongly

interested the profession, that the new practice became quickly popular,

in spite of a warm though partial opposition, which was put down in the

summer of 1799 by a manifesto expressive of confidence in its efficacy

and safety, signed by seventy-three of the most eminent medical men in

the metropolis. In the same year some unfortunate occurrences took place

in consequence of Dr. Woodville, the physician of the Small-pox

Hospital, having incautiously used and distributed matter from persons

whom he had inoculated with small-pox a few days after vaccination,

before it had taken a sufficient hold. The mongrel lymph thus produced

sometimes occasioned one, sometimes the other disease; their effects

were confounded; and some deaths which ensued, as well as a general

eruption of the skin which took place in many instances, were attributed

to the cow-pox. This and other mistakes would probably have much

retarded the general adoption of vaccination, but for the promptitude of

Jenner to discover and expose the source of the error.

In 1802 a parliamentary inquiry into the value of the new method of

preventing small-pox, including Jenner’s claim to the discovery of it,

was instituted, and a grant was voted to him of 10,000_l._ In 1807 he

received an additional vote of 20,000_l._, which, considering that he

had been the instrument of saving in England alone at least 45,000 lives

annually, will seem by no means an extravagant mark of national

gratitude and respect.

In 1803 the Royal Jennerian Society, for the encouragement of

vaccination, was established in London under the superintendence of Dr.

Jenner. In 1808 this society was merged by his advice in the National

Vaccine Establishment, which still continues to dispense the blessings

of the antidote at the public charge.

The Gallery of Portraits: with Memoirs. Volume 6 (of 7) · 第 1 / 19 段