I. _Detail of_ MR. J. W. TOBIN.

Having seen the remarkable effects produced on Mr. Davy, by breathing

nitrous oxide, the 18th of April; I became desirous of taking some.

A day or two after I breathed 2 quarts of this gas, returning it back

again into the same bag, after two or three in inspirations, breathing

became difficult, and I occasionally admitted common air into my

lungs. While the respiration was continued, my sensations became more

pleasant. On taking the bag from my mouth, I staggered a little, but

felt no other effect.

On the second time of making the experiment, I took nearly four quarts,

but still found it difficult to continue breathing long, though the air

which was left in the bag was far from being impure.

The effects however, in this case, were more striking than in the

former. Increased muscular action was accompanied by very pleasurable

feelings, and a strong desire to continue the inspiration. On removing

the bag from my mouth, I laughed, staggered, and attempted to speak,

but stammered exceedingly, and was utterly unable to pronounce some

words. My usual state of mind, however, soon returned.

On the 29th, I again breathed four quarts. The pleasant feelings

produced at first, urged me to continue the inspiration with great

eagerness. These feelings however, went off towards the end of the

experiment, and no other effects followed. The gas had probably been

breathed too long, as it would not support flame. I then proposed to

Mr. Davy, to inhale the air by the mouth from one bag, and to expire

it from the nose into another. This method was pursued with less than

three quarts, but the effects were so powerful as to oblige me to take

in a little common air occasionally. I soon found my nervous system

agitated by the highest sensations of pleasure, which are difficult

of description; my muscular powers were very much increased, and I

went on breathing with great vehemence, not from a difficulty of

inspiration, but from an eager avidity for more air. When the bags

were exhausted and taken from me, I continued breathing with the same

violence, then suddenly starting from the chair, and vociferating with

pleasure, I made towards those that were present, as I wished they

should participate in my feelings. I struck gently at Mr. Davy and a

stranger entering the room at the moment, I made towards him, and gave

him several blows, but more in the spirit of good humour than of anger.

I then ran through different rooms in the house, and at last returned

to the laboratory somewhat more composed; my spirits continued much

elevated for some hours after the experiment, and I felt no consequent

depression either in the evening or the day following, but slept as

soundly as usual.

On the 5th of May, I again attempted to breathe nitrous oxide, but

it happened to contain suspended nitrous vapour which rendered it

non-respirable.

On the 7th, I inspired 7 quarts of pure gas mingled with an equal

quantity of common air, the sensations were pleasant, and my muscular

power much increased.

On the 8th, I inspired five quarts without any mixture of common air,

but the effects were not equal to those produced the day before; Indeed

there were reasons for supposing that the gas was impure.

On the 18th, I breathed nearly six quarts of the pure nitrous oxide. It

is not easy to describe my sensations; they were superior to any thing

I ever before experienced. My step was firm, and all my muscular powers

increased. My senses were more alive to every surrounding impression;

I threw myself into several theatrical attitudes, and traversed the

laboratory with a quick step; my mind was elevated to a most sublime

height. It is giving but a faint idea of the feelings to say, that they

resembled those produced by a representation of an heroic scene on the

stage, or by reading a sublime passage in poetry when circumstances

contribute to awaken the finest sympathies of the soul. In a few

minutes the usual state of mind returned. I continued in good spirits

for the rest of the day, and slept soundly.

Since the 18th of May, I have very often breathed nitrous oxide. In

the first experiments when pure, its effects were generally similar to

those just described.

Lately I have seldom experienced vivid sensations. The pleasure

produced by it is slight and tranquil, I rarely feel sublime emotions

or increased muscular power.

J. W. TOBIN.

_October, 1799._

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