GENERAL PRINCIPLES OF TREATMENT OF SKIN DISEASES.

General and local. Diet: wholesome diet following laxative:

restricted, generous, vegetable. Rest, avoiding congestion,

perspiration, friction, stretching, pressure. Cleanliness. Diuretics.

Purgatives. Tonics. Alteratives. Sulphur. Antimony. Phosphorus.

Calcium sulphide. Pilocarpin. Baths, tepid, warm, soapy, alterative.

Emollients, simple, medicated. Drying powders. Protective films.

Stimulating and antiseptic applications. Parasiticides. Caustics.

Counter-irritants. Bandages.

These must be general and local, and the first hygienic, dietetic and

medicinal.

The =diet= is especially important in eruptions due to poisons such as

green food, distillery refuse, silage, roots, ergoted or smutty food,

musty fodder, irritant plants in hay or grain feed, buckwheat, etc. In

many cases a change to sound fodder and a laxative to clear the

alimentary canal of the irritant, may be all that is required. In cases

where the feeding has been parsimonious, a judiciously gradual change to

a generous diet may be required. Again when the feed has been unduly

rich, or spiced as in the patent food for stock or the table leavings

for dogs, a plainer, simpler and less exciting diet will be called for.

Indigestions, urinary and hepatic disorders due to diet may be often

corrected by a more judicious ration.

=Rest= is a most important element in horses and hunting dogs. When

pressure of the harness keeps up the irritation, or when active movement

reopens cracks in the tense rigid congested skin of the heel, carpus or

tarsus of the horse, the parts must be kept quiescent. When on the other

hand chaps and fissures are caused and maintained by _stocking_, the

patient may do much better with exercise. In skin congestions which are

aggravated by work and increased cutaneous circulation, rest is

imperative.

=Cleanliness= is no less imperative. Many cases are started and

maintained by filth on the skin and in the air of the stable and hence

sponging, currying, brushing, rubbing, are directly therapeutic. Yet

care must be taken to avoid irritation where the skin is tender. In the

sensitive heels of the horse congestion, chaps, and _stocking_ are often

determined by washing in ice cold water and leaving to dry uncovered, in

a draught of air, or by washing with common laundry soap having alkali

in excess. Even tar soap will sometimes keep up the trouble in a

specially sensitive skin. Apart from such exceptional conditions,

thorough grooming is commendable, not only in cleaning the skin, but in

improving its circulation and nutrition.

=Diuretics= are often beneficial in eliminating from the system the

irritant products generated from disorders in sanguification, digestion,

urinary secretion and hepatic function, as well as those that are

derived from the cutaneous disorder. They tend further to reduce any

existing fever, and to cool and relieve the burning integument. The

alkaline diuretics are often very useful.

=Purgatives= act in a similar way and are especially indicated in cases

due to ingested irritants, and in such as depend on morbid products of

gastro-intestinal or hepatic disorder. In many acute attacks these may

be said to be almost specific in their action as in urticaria, and in

the eruptions due to distillery products or green food.

=Tonics= are often called for to correct dyspepsias, to improve the

general health and vigor, the sanguification and nutrition in weak and

debilitated conditions. Iron, cod liver oil, bitters, quinia, quassia,

calumba, gentian, nux, are often of value in such cases.

=Alteratives.= =Arsenic= may be said to act as a tonic with a special

tendency toward the skin where it affects the epidermis and epidermic

products and is applicable to many subacute and chronic disorders, as

psoriasis, acne, dry eczema, and pemphigus. It has been further supposed

to be most useful in superficial lesions, and in those due to a neurotic

origin, from the known operation of arsenic on the nerves. It is little

suited to acute skin diseases, and though often valuable is not to be

trusted as universally applicable.

=Sulphur= is often useful as a laxative, but also as a stimulant to the

cutaneous secretions when these are impaired.

=Antimony= is similarly a cutaneous stimulant and is sometimes useful in

chronic inactive conditions.

=Phosphorus= has been found useful in obstinate cases and probably acts

on the nerve centres in improving nutrition of the integument.

=Calcium sulphide= is sometimes useful with free secretion from the

diseased surface, but its action is somewhat uncertain.

=Pilocarpin= operates by securing free secretion from the skin as well

as from the various mucosæ, and seems to benefit by elimination, as well

as by modifying the cutaneous functions and nutrition.

=Local Applications.= =Baths= may be placed foremost among these.

Cleanliness is a prime necessity in treating skin disease. Tepid or warm

water is especially required in acute disease in sensitive skins. In

chronic cases with accumulation of scabs a soap wash following a 24

hours inunction with oil or lard may be demanded, but as a rule castile

or other non-caustic soap should be used. In certain cases the baths may

be advantageously medicated, as with calcium sulphide, potassium

sulphide, salt, alum, tannic acid, tar, creolin, lysol, cresol,

chloro-naphtholeum, arsenic, mercury, etc. The water alone is, however,

of great value in soothing and moderating inflammation, softening and

dissolving scabs and epidermis, and relieving the dryness and rigidity.

=Emollients= are used for the same end as calmatives, and relaxing and

protective agents. Fatty bodies occupy a front rank, the bland vegetable

and animal oils being not only soothing but nutritive (cod, lard, olive,

cotton, almond, linseed, rape, pea nut, lanolin, neats foot and goose

oil). Care should be taken that these are pure and in no sense rancid.

Vaseline or petrolatum are free from the risk of rancidity, yet it

should be free from contamination unless a stimulating action is wanted.

Glycerine often used as an emollient has the disadvantage of drawing

water from the surface and of actually irritating some sensitive skins.

Glycerol made with glycerine and starch is more soothing. Glycogelatine

made with glycerine 5, gelatine 3, and water 9, is very emollient and

protective. This can be made the basis of astringent, sedative and

antiseptic preparations by adding zinc oxide, lead acetate, chrysarobin,

salicyclic acid, tannin, sulphur, oil of birch or of tar, etc. An

excellent emollient paste is compounded of zinc oxide and vaseline

one-half ounce of each, salicylic acid, ten grains. Oleate of lead is an

excellent sedative application in irritation or pruritus.

=Drying powders= are found in starch, talc, magnesia, zinc oxide,

lycopodium, bismuth oxide, boric acid, iodoform, aristol, salicylic

acid, tannin, and, above all, magnesia carbonate. A slight addition of

morphia sulphate will render them analgesic. Tar in zinc oxide or

bismuth will secure antiseptic and stimulating qualities.

=Protective films= for irritable surfaces may be had from collodion, or

from a solution of gutta percha in chloroform 1 ∶ 10 (traumaticin).

=Stimulating and antiseptic applications= are found in tar or oil of tar

in suitable excipient and of a strength suited to the case, oil of white

birch, oil of lavender, oil of cade, oil of cashew nut, oil of juniper,

oil of hemlock, Canada balsam, balsam of Tolu or Peru, creolin, lysol,

cresyl, creosote, carbolic acid, chloro-naphtholeum, etc. Ichthyol, of

great value in chronic affections, may be used in oil or vaseline (5 ∶

100), or in the form of Nuna’s varnish: Ichthyol 40, starch 40,

concentrated albumen solution 1 to 1½, and water 20. Add the water to

the starch, then rub in the ichthyol and finally the albumen. Resorcin

is a useful stimulant, alterative, and antipruritic (1 ∶ 30 alcohol and

oil).

As =antiseptics= and =parasiticides=, in addition to the above, are

alpha- and beta-naphthol, iodized phenol, chloral camphor (rub together

till they form a clear fluid), phenol camphor (add camphor gradually to

the melted phenol crystals), mercuric chloride, cupric sulphate and

silver nitrate. Potash (green) soap, medicated or not with tar or other

agent, is of great use in many chronic affections. The phenol

combinations are all more or less anæsthetic, and therefore sedatives

and antipruritic. Quassia, Stavesacre, tobacco, etc., are of great use

in parasitisms though not antiseptic. Sulphur fills both indications,

and is a bland generally applicable agent.

=Caustics= (silver nitrate, antimony chloride, electric or

thermocautery) are useful in luxuriant granulations, hyperplasias, and

often in excessive secretion, or on infected surfaces.

=Counter-irritation= over the vaso-motor centres, is often of value,

when the distribution of the eruption coincides with that of particular

nerves, and indicates a nervous element in the causation.

=Bandages= of various kinds may be demanded to afford support in

threatened dropsical effusion or excessive granulation or hyperplasia,

to protect the surface against outside infection, to confine volatile

applications to the affected part, and to prevent injury from biting,

licking, scratching, or rubbing.

For the same reason it may be desirable to employ a muzzle, beads on the

neck, tying to two opposite rings by short halters, hobbles, or other

means of restraint.

Text book of veterinary medicine, Volume 3 (of 5) · 第 234 / 294 题