INFECTIOUS CONJUNCTIVITIS IN HERBIVORA. ENZOOTIC OPHTHALMIA.

Causes: infection, pollen, soil emanation, winter or summer; cases of

extension by infection. Cattle, sheep, goats, ponies. Accessory

irritants. Symptoms: severe purulent conjunctivitis. Papillary and

follicular hypertrophy, uniform redness, protruding head, opacities,

erosions, ulcers, photophobia, staphyloma. Treatment: rest, darkness,

coolness, elevated head, purgative, diuretics, sedatives; locally

solutions of pyoktannin, sublimate, silver nitrate, boric or salicylic

acid, atropia, puncture.

_Causes._ This affection which attacks at once or in rapid succession a

large portion or the whole of a herd or flock, is by many held to be

infectious while others attribute it to irritant pollen or soil

emanation. Its origin from vegetation in flower is held to be supported

by its greater frequency in summer than in winter, and the few outbreaks

seen in winter are attributed to pollen preserved in the hay. But other

things being equal, organized germs are preserved, multiplied and

diffused to a greater extent in the hot season so that the origin of the

disease from a purely microbian source is at least equally plausible.

Certain outbreaks indeed show the transmission of the infection in a

most unequivocal manner. A cow suffering from the affection was brought

into a stable occupied by a herd previously sound, and in a few days the

cow standing next her was attacked, and thereafter a number of others in

rapid succession. A small number of cattle from the Buffalo Stock Yards,

but which had sore eyes on their arrival in Tompkins Co., N. Y., were

placed in a sound herd and the disease spread rapidly to the other

members of the herd. Similarly in both sheep and cattle the writer has

seen the disease prevail in one herd or flock, while the adjacent herd

or flock, separated only by a good stone wall and subject to exactly the

same condition of soil, water, exposure, vegetation and pollen has

entirely escaped. Kaiser has seen it introduced into a herd by a bull;

Fünfstück saw a herd of 300 head attacked in a few days, and Klink 20

out of a herd of 40 head in 14 days. Trumbower has never seen an animal

suffer a second time. This is the common experience and would suggest an

acquired immunity, yet the comparative rarity of the disease forbids a

positive conclusion, without further experience. Menard saw an outbreak

among the ponies in the Jardin d’Acclimatation, and as many as fourteen

weeks later in the same gardens it attacked the bovine animals.

In sustaining the doctrine of infection, however, we must not altogether

ignore accessory causes. Like other affections of the eye, this has

seemed to appear especially in low, damp lands, bottom lands, deltas,

marshy borders of lakes and level prairies, so that a general lack of

tone or a lymphatic constitution may be held to predispose. Nor is it

necessary to ignore the influence of pollen, dust and other irritants,

which though they may not cause the specific disease, yet prepare the

way for its attack by reducing the resisting power of the tissues.

_Symptoms._ These are the phenomena of severe purulent conjunctivitis.

Closed eyes; profuse secretion of tears, sometimes mixed with blood,

changing in a few days to a thick, purulent, white or yellow secretion,

which collects in masses inside the lids, along their margins, in the

inner canthus and on the cheeks, gluing together the cilia, lids and

hairs. When separated the lids show a mucosa of an uniform deep red,

covered with pus, and irregularly swollen according to the amount of

infiltration. Papillary and follicular hypertrophy are marked features,

and the nictitans projects excessively over the eyeball. In many cases

the cornea becomes opaque and in some instances erosions occur which may

cause perforation or loss of the eye. In other instances the ulcers heal

with the formation of cicatrices, or the weakened portion of the

membrane yields under the internal tension and staphyloma supervenes. In

such cases the pupils are contracted.

The disease is usually attended by marked hyperthermia, the secretions,

including the lacteal, are materially decreased, appetite and rumination

are impaired and the animal leaves the flock or herd. The disease

affects cattle and sheep, and Menard and Hoffmann add horses and goats.

_Treatment._ This must be primarily antiseptic, but without neglecting

constitutional disorder. Rest in a dark, cool stall, with the head

elevated by tying to a high point. Give at once an active purgative 1½

lb. Glauber salts in 4 quarts warm water, and follow up with cooling

diuretics and sedatives (saltpeter ½ oz. and tincture of aconite 20

drops, thrice a day). If the temperature runs very high a few doses of

acetanilid or phenacetin may be given. Locally use silver or other

antiseptic collyrium.

_Locally_ use pyoktannin solution (1 ∶ 1000) or mercuric chloride (1 ∶

5000) injecting under the lids so as to bring it in contact with the

whole diseased surface. A cloth wet with the same solution may be hung

over the eye. Boric acid (1 ∶ 100), salicylic acid (1 ∶ 1000), or silver

nitrate (1 ∶ 100) may be substituted for the above when they seem to be

losing their efficacy.

Ulcers are treated by pyoktannin or silver nitrate solution applied

daily with a soft brush. Keratitis will demand atropia. Abnormal tension

or staphyloma will demand puncture of the cornea. Improvement may be

expected in a few days and recovery in a week or ten days.

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