PURULENT NEPHRITIS.

Causes: general, traumatic, metastatic, infective, wounds, shocks,

strains, blows, falls, crowding, heavy loads, calculi, infective

embolism. Lesions: miliary or large abscesses, diffuse suppuration,

softening, disintegration, fistula. Symptoms: obscure, nephritic

symptoms following distant abscess, chill, hyperthermia, general

symptoms of nephritis, pus in urine, anæmia, emaciation. Treatment: to

external wound, antiseptics, evacuate abscess, extirpate kidney with

pyonephrosis, in dog or pig, calcium sulphide, sulphites, copiaba.

_Causes._ Aside from the main causes of nephritis, the suppurative form

may be determined by traumatic or metastatic infective conditions. Under

_traumatic_ factors may be named punctured or gunshot wounds, shocks and

strains connected with falls, blows, crowding, compression, too heavy

weights on the back (pack, rider, two wheeled cart loaded too heavily

forward and going down hill), and finally calculi in the uriniferous

tubules. Under _metastatic_ factors come all infections, pyæmia,

omphalitis, any suppurative affection of the lungs, (abscess, pneumonia,

broncho-pneumonia), pharyngitis, etc. Embolic renal abscess may start

from endocarditis, arteritis, or pulmonary phlebitis.

_Lesions._ There may be a circumscribed renal abscess like a good large

orange, or many small gray spots like millet seeds, peas or hazel nuts,

having purulent centres and containing pus cocci or bacilli. In other

cases a diffuse inflammation suppurates throughout till the whole gland

becomes a pulpy mass of pus, blood and broken down kidney tissue

(pyonephrosis). In traumatic cases the pus centres around the wound or

injury, perhaps invading adjacent parts, and even communicating through

the skin externally along the line of the original wound. The pus may

burrow in different directions in the cortex or under the capsule with

abscess at intervals (perinephritis), or along the vessels to the

medullary structure.

_Symptoms._ These are often obscure. The sudden appearance of kidney

disease in the course of a suppurative affection elsewhere, the

extension being ushered in by a chill or rigor or attended by a

succession of these, and the course marked by a variable hyperthermia is

very suggestive. Stiffness and weakness of the hind parts and tenderness

of the loins are significant; also, in carnivora and omnivora, nausea

and vomiting. When the kidney can be felt by the hand in the rectum or

in the small animals, through the flaccid abdominal walls, the manifest

enlargement, the tenderness, and in some cases even fluctuation will

assist in diagnosis. In such cases, puncture by a large hypodermic

needle, or a small trochar may betray the presence of pus and complete

the diagnosis. If the pus escapes into the pelvis of the kidney it may

be recognized in the urine. The case is very liable to become chronic,

and is then marked by anæmia and emaciation.

_Treatment._ When an external wound exists it must be treated,

antiseptically, with boric acid, potassium permanganate, or other

antiseptic lotion. If a single large abscess exists, puncture evacuation

through needle or trochar, and washing out with an antiseptic solution

is the obvious resort. Any foreign body must of course be removed. If

the suppuration is diffused through the whole mass of softened kidney,

the resort of extirpation may be considered. This is always dangerous as

provocative of infectious peritonitis, but it is less so in dogs and

swine than in other animals owing to their natural antagonism to pus

microbes. The operation should be attempted extraperitoneally, the

incision being made beneath the anterior lumbar transverse processes and

carried inward through the sublumbar connective tissue. The renal artery

will require ligature with antiseptic catgut and all manipulations

should be aseptic or antiseptic. Even if successful, this operation

leaves the subject in a dangerous state, as in case of kidney disease at

any future time, there is no second kidney to compensate for the

temporary loss of function and uræmic poisoning is to be dreaded.

Apart from surgical measures the general treatment would be largely the

same as for acute infectious nephritis. As antiseptics calcium sulphide,

the different sulphites, copiaba, etc., will be indicated.

Text book of veterinary medicine, Volume 3 (of 5) · 第 78 / 294 题