_Treatment._--The means recommended to bring the acute abscess "to a

head" are but rarely effectual with this variety; or, if successful, too

much time has been occupied in the cure. We must look for other and more

rapid methods of treatment. These consist, first of all, in carefully

exploring the tumor for the presence of pus. The incisions must be made

over the softest part and carried deep into the tumor--to its very

bottom, if necessary--and the matter allowed to escape. After this, and

whether we have found matter or not, we must induce an active

inflammation of the tumor, in order to promote solution of the thick

walls of the abscess. This may be done by inserting well into the

incision a piece of oakum or cotton saturated with turpentine, carbolic

acid, tincture of iodin, etc., or we may pack the incision with powdered

sulphate of zinc and keep the orifice plugged for 24 hours. These agents

set up a destructive inflammation of the walls. Suppuration follows, and

this should now be encouraged by hot fomentations and poultices. The

orifice must be kept open, and should it be disposed to heal we must

again introduce some of the agents above described. A favored treatment

with many, and it is probably the best, is to plunge a red-hot iron to

the bottom of the incision and thoroughly sear all parts of the walls of

the abscess. This is to be repeated after the first slough has taken

place if the walls remain thickened and indurated.

It is useless to waste time with fomentations, poultices, or blisters in

the treatment of cold abscesses, since though apparently removed by such

methods, they almost invariably return when the horse is put to work.

Extirpation by the knife is not practicable, as the walls of the tumor

are not sufficiently defined. If treated as above directed, and properly

fitted with a good collar after healing, there will not remain any track

or trace of the large, unsightly mass.

FISTULAS.

_Definition._--The word fistula is applied to any ulcerous lesion upon

the external surface of the body which is connected by ducts, or

passages, with some internal cavity. Because of this particular

formation the term fistulous tract is often used synonymously with the

word fistula. Fistulas may exist in any part of the body, but the name

has come to be commonly accepted as applicable only to such lesions when

found upon the withers. Poll evil is a fistula upon the poll, and in no

sense differs from fistulous withers except in location. The description

of fistula will apply, then, in the main, to poll evil equally well.

Quittor presents the characteristic tubular passages of a fistula and

may, therefore, be considered and treated as fistula of the foot.

Fistulous passages may also be developed upon the sides of the face,

through which saliva is discharged instead of flowing into the mouth,

and are called salivary fistulas. A dental fistula may arise from the

necrosis of the root of a tooth. Again, a fistula is sometimes noted at

the umbilicus associated with hernia, and recto-vaginal fistulas have

been developed in mares, following difficult parturition. Fistulas may

arise from wounds of glandular organs or their ducts, and thus we have

the so-called mammary or lacrimal fistulas.

Fistulous tracts are lined with a false, or adventitious, membrane and

show no disposition to heal. They constantly afford means of exit to the

pus or ichorous material discharged by the unhealthy parts below. They

are particularly liable to develop at the withers or poll because of the

exposed positions which these parts occupy, and, having once become

located there, they usually assert a tendency to further extension,

because the vertical and laminated formation of the muscles and tendons

of these parts allows the forces of gravitation to assist the pus in

gaining the deeper-lying structures and also favors its retention among

them.

_Causes._--Fistulas follow as a result of abscesses, bruises, wounds, or

long-continued irritation by the harness. Among the more common causes

of fistula of the poll (poll evil) are chafing by the halter or heavy

bridle; blows from the butt end of the whip; the horse striking his head

against the hayrack, beams of the ceiling, low doors, etc. Fistulous

withers are seen mostly in those horses that have thick necks as well as

those that are very high in the withers; or, among saddle horses, those

that are very low in the withers, the saddle here riding forward and

bruising the parts. In either of these locations ulcers of the skin, or

simple abscesses, if not properly and punctually treated, may become

fistulas. They are often caused by bad-fitting collars or saddles, by

direct injuries from blows, and from the horse rolling upon rough or

sharp stones. The pus burrows and finds lodgment deep down between the

muscles, and escapes only when the sinus becomes surcharged or when,

during motion of the parts, the matter is forced to the surface.

_Symptoms._--These, of course, will vary according to the progress made

by the fistula. Following an injury we may often notice soreness or

stiffness of the front legs, and upon careful examination of the withers

we see small tortuous lines running from the point of irritation

downward and backward over the region of the shoulder. These are

superficial lymphatics, and are swollen and painful to the touch. In a

day or two a swelling is noticed on one or both sides of the dorsal

vertebrae, which is hot, painful, and rapidly enlarging. The stiffness of

the limbs may disappear at this time, and the heat and soreness of the

parts may become less noticeable, but the swelling remains and continues

to enlarge.

A fistulous ulcer of the poll may be first indicated by the opposition

which the animal offers to the application of stable brush or bridle. At

this time the parts are so sore and sensitive that there is some danger

that unless handled with the greatest care the patient will acquire

disagreeable stable habits. The disease in its early stages may be

recognized as a soft, fluctuating tumor surrounded by inflammatory

swelling, with the presence of enlarged lymphatic vessels and stiffness

of the neck. Later the inflammation of the surrounding tissues may

disappear, leaving a prominent tumor. The swelling, whether situated

upon the head or the withers, may open and form a running ulcer, or its

contents may dry up and leave a tumor which gradually develops the

common characteristics of a fibrous tumor. When the enlargement has

opened we should carefully examine its cavity, as upon its condition

will wholly depend our treatment.

_Treatment._--In the earliest stage, when there is soreness, enlarged

lymphatics, but no well-marked swelling, the trouble may frequently be

aborted. To do this requires both general and local treatment. A physic

should be given, and the horse receive 1 ounce of powdered saltpeter

three times a day in his water or feed. If the fever runs high, 20-drop

doses of tincture of aconite root every two hours may be administered.

The local application of cold water to the inflamed spot for an hour at

a time three or four times a day has often proved very beneficial, and

has afforded great relief.

Cooling lotions, muriate of ammonia, or saltpeter and water; sedative

washes, such as tincture of opium and aconite, chloroform liniment, or

camphorated oil, are also to be frequently applied. Should this

treatment fail to check the progress of the trouble, the formation of

pus should be hastened as rapidly as possible. Hot fomentations and

poultices are to be constantly used, and as soon as the presence of pus

can be detected, the abscess wall is to be opened at its lowest point.

In this procedure lies our hope of a speedy cure. As with any simple

abscess, if drainage can be so provided that the pus will run off as

fast as formed without remaining within the interstices of the tissues,

the healing will be rapid and satisfactory.

Attention is again called to the directions given above as to the

necessity of probing the cavity when opened. If upon a careful

examination with the probe we find that there are no pockets, no

sinuses, but a simple, regular abscess wall, the indication for

treatment is to make an opening from below so that all the matter must

escape. Rarely is anything more needed than to keep the orifice open and

to bathe or inject the parts with some simple antiseptic wash that is

not irritant or caustic. A low opening and cleanliness constitute the

essential and rational treatment.

If the abscess has already opened, giving vent to a quantity of purulent

matter, and the pipes and tubes leading from the opening are found to be

extensive and surrounded with thick fungoid membranes, there is

considerable danger that the internal ligaments or even some of the

bones have become affected, in which case the condition has assumed a

serious aspect. Or, on the other hand, if the abscess has existed for

some time without a rupture, its contents will frequently be found to

consist of dried purulent matter, firm and dense, and the walls

surrounding the mass will be found greatly thickened. In such a case we

must generally have recourse to the application of caustics which will

cause a sloughing of all of the unhealthy tissue, and will also

stimulate a rapid increase of healthy organized material to replace that

destroyed in the course of the development and treatment of the disease.

Threads or cords soaked in gum-arabic solution and rolled in powdered

corrosive sublimate may be introduced into the canal and allowed to

remain. The skin on all parts of the shoulder and leg beneath the

fistula should be carefully greased with lard or oil, as this will

prevent the discharge that comes from the opening after the caustic is

introduced from irritating or blistering the skin over which it flows.

In obstinate cases a piece of caustic potash (fused) 1 to 2 inches in

length may be introduced into the opening and should be covered with

oakum or cotton. The horse should then be secured so that he can not

reach the part with his teeth. After the caustic plug has been in place

for 24 hours, it may be removed and hot fomentations applied. As soon as

the discharge has become again established the abscess should be opened

from its lowest extremity, and the passage thus formed may be kept open

by the introduction of a seton. If the pipes become established in the

deep tissues beneath the shoulder blade or among the spines of the

vertebral column, it will often be found impossible to provide proper

drainage for the abscess from below, and treatment must consist of

caustic solutions carefully injected into all parts of the suppurating

sinuses. A very effective remedy for this purpose consists of 1 ounce of

chlorid of zinc in half a pint of water, injected three times during a

week, after which a weak solution of the same may be occasionally

injected. Injections of Villate's solution or alcoholic solution of

corrosive sublimate, strong carbolic acid, or possibly oil of turpentine

will also prove beneficial. Pressure should be applied from below, and

endeavors made to heal the various pipes from the bottom.

Should the swelling become general, without forming a well-defined

tumor, the placing of 20 to 30 grains of arsenious acid, wrapped in a

single layer of tissue paper, in a shallow incision beneath the skin,

will often produce a sloughing of the affected parts in a week or 10

days, after which the formation of healthy tissue follows. The

surrounding parts of the skin should be protected from any damage from

escaping caustics by the application of lard or oil, as previously

suggested.

Although the successful treatment of fistulas requires time and

patience, the majority of cases are curable. The sinuses must be opened

at their lowest extremity and kept open. Caustic applications must be

thoroughly used once or twice, after which mild astringent antiseptic

washes should be persistently used until a cure is reached.

It sometimes happens that the erosions have burrowed so deeply or in

such a direction that the opening of a drainage passage becomes

impracticable. In other cases the bones may be attacked in some

inaccessible location, or the joints may be affected, and in these cases

it is often best to destroy the horse at once.

The reappearance of the fistula after it has apparently healed is not

uncommon. The secondary attack in these cases is seldom serious. The

lesion should be carefully cleaned and afterwards injected with a

solution of zinc sulphate, 20 grains to the ounce of water, every second

or third day until a cure is effected.

In fistula of the foot we see the same tendency toward the burrowing of

pus downward to lower structures, or in some cases upward toward the

coronet. Prior to the development of a quittor there is always swelling

at the coronet, accompanied with heat and pain. Every effort should now

be made to prevent the formation of an abscess at the point of injury.

Wounds caused by nails, gravel, or any other foreign body which may have

lodged in the sole of the foot should be opened at once from below, so

as to allow free exit to all purulent discharges. Should the injury have

occurred directly to the coronet the application of cold fomentations

may prove efficient in preventing the formation of an abscess.

When a quittor becomes fully established it should be treated precisely

as a fistula situated in any other part of the body; that is, the

sinuses should all be opened from their lowest extremities, so as to

afford constant drainage. All fragments of diseased tissue should be

trimmed away, antiseptic solutions injected, and, after covering the

wound with a pad of oakum saturated with some good antiseptic wash, the

whole foot may be carefully covered with clean bandages, which will

afford valuable assistance to the healing process by excluding all dirt

from the affected part.

Another form of treatment for this class of infections consists in the

use of bacterial vaccines. Such treatment appears to be well adapted for

the purpose, and according to current veterinary literature has met with

success. These vaccines are composed of several strains of the organisms

usually found in these pustular infections of the horse. Two kinds of

vaccines are used: First, autogenic vaccines, which consist of heated

(killed) cultures of the organism or organisms which are causing the

trouble and which have been isolated from the lesions; second, stock

vaccines, consisting of dead organisms of certain species generally

found in these lesions and which are used in diseased conditions caused

by one or the other of these germs. The vaccine is administered

subcutaneously by means of a syringe, but the quantity of the vaccine to

be injected and the number of doses to be used should be left to the

judgment of a competent veterinarian.

INFECTIOUS DISEASES.

By RUSH SHIPPEN HUIDEKOPER, M. D., Vet.

[Revised by A. Eichhorn, D. V. S.]

GENERAL DISCUSSION.

An infectious disease may be defined as any malady caused by the

introduction into the body of minute organisms of the vegetable or

animal kingdom which have the power to multiply indefinitely and set

free certain peculiar poisons which are chiefly responsible for morbid

changes. Nearly all diseases of animals for which a definite cause may

be attributed are caused by bacteria; such are tuberculosis, anthrax,

blackleg, lockjaw, and others. There are some diseases, as, for

instance, Texas fever and rabies, which are caused by a minute animal

parasite known as protozoa, while others again, like lumpy jaw and

aspergillosis, are caused by fungi. Besides there are infectious

diseases in which the causative agents have never been successfully

isolated, as they are so small that they can not be detected by the aid

of the most powerful microscope, and accordingly they are termed as

ultravisible viruses. Hog cholera, foot-and-mouth disease, smallpox, and

others belong to this group.

Bacteria may be defined as very minute unicellular organisms of

plantlike character. They multiply either by simple division or by spore

formation, the latter usually taking place when the conditions

pertaining to the growth of the bacteria become unfavorable. The spores

are much more resistant to destruction than the bacteria which produce

them.

Another group of parasites producing disease is known as protozoa. These

are more complex than bacteria, and their artificial cultivation is also

much more difficult than is the case with the bacterial parasites. Of

the representatives of this group, causing disease in animals, are the

trypanosomes, which are the causative factors of dourine and surra, and

the piroplasma, which induce Texas fever in cattle and malaria or

biliary fever of horses. There are also disease-producing fungi which

are responsible for certain affections in horses; among these the most

important are mycotic lymphangitis, or sporotrichosis, and

streptotrichosis.

The introduction of the infection may take place in various ways. The

most frequent method is by ingestion. Further, the entrance of the

germs may occur by inhalation, skin abrasions, wounds of any kind,

through the genital organs, and at times also through the milk ducts of

the teats. As a general rule infectious diseases have a period of

incubation which comprises the time elapsing between the exposure to the

infection and the actual appearance of the disease. This period varies

in the different diseases.

The treatment of infectious diseases is, as a rule, unsatisfactory. When

the symptoms have once appeared a disease is liable to run its course in

spite of treatment, and if it is one from which animals usually recover,

all that can be done is to put them into the most favorable

surroundings. Many infectious diseases lead sooner or later to death;

treatment is useless so far as the sick animals are concerned, and it

may be worse than useless for those not yet affected. All animals

suffering with infectious diseases are more or less directly a menace to

all others. They represent for the time being manufactories of disease

germs, and they are giving them off more or less abundantly during the

period of disease. They may infect others directly or they may scatter

the virus about and the surroundings may become the future source of

infection.

Therefore, in the control of infectious diseases prevention is the most

important procedure. The isolation or segregation of healthy animals

from infected ones should be primarily considered, and if at any time an

animal manifests the symptoms of an infectious disease it is essential

to protect the others from such a source of danger. In some of the

infectious diseases it may become advisable to kill the infected animals

in order to avoid the spread of the disease. This is especially

important in diseases which are slow in their course, such as

tuberculosis. At times when diseases appear in a country where they have

not been prevalent it becomes advisable and necessary to protect the

healthy herds by the slaughter of all the infected animals. Pursuance of

this policy has resulted in control of the foot-and-mouth disease, and

has proved to be a very satisfactory method of eradication.

DISINFECTION.

Disinfection is a very important phase in the control of infectious

disease. This consists in the use of certain substances which possess

the power to destroy bacteria or their spores, or both. The cheapest and

most available for animal diseases are ordinary freshly slaked lime, or

unslaked lime in powder form, chlorid of lime, crude carbolic acid,

corrosive sublimate, formalin, formaldehyde, gas, cresol, etc.

In the disinfection of stables and premises it is essential to execute

the work in a most thorough manner. This may be satisfactorily

accomplished by carrying out the following directions:

1. Sweep ceilings, side walls, stall partitions, floors, and other

surfaces until free from cobwebs and dust.

2. Scrape away all accumulation of filth, and if woodwork has become

decayed, porous, or absorbent, it should be removed, burned, and

replaced with new material.

3. If floor is of earth, remove 4 inches from the surface, and in places

stained with urine a sufficient depth should be replaced to expose fresh

earth. All earth removed should be replaced with earth from an

uncontaminated source; it would be better still to lay a new floor of

concrete, which is very durable and easily cleaned.

4. All refuse and material from stable and barnyard should be removed to

a place not accessible to cattle or hogs. The manure should be spread on

fields and turned under, while the wood should be burned.

5. The entire interior of the stable, especially the feeding troughs and

drains, should be saturated with a disinfectant, as liquor cresolis

compositus (U. S. P.), or carbolic acid, 6 ounces to every gallon of

water, to which 4 ounces of chlorid of lime should be added. The best

method of applying the disinfectant and the lime wash is by means of a

strong spray pump, such as those used by orchardists. This method is

efficient in disinfection against most of the contagious and infectious

diseases of animals, and should be applied immediately following any

outbreak, and, as a matter of precaution, it may be used once or twice

yearly.

6. It is important that arrangements be made to admit a plentiful supply

of sunlight and fresh air by providing an ample number of windows,

thereby eliminating dampness, bad odor, and other insanitary conditions.

Good drainage is also very necessary.

If the use of liquor cresolis compositus, carbolic acid, or other

coal-tar products is inadmissible because of the readiness with which

their odor is imparted to milk and other dairy products, bichlorid of

mercury may be used in proportion of 1 to 800, or 1 pound of bichlorid

to 100 gallons of water. All portions of the stable soiled with manure,

however, should first be thoroughly scraped and cleaned, as the albumin

contained in manure would otherwise greatly diminish the disinfecting

power of the bichlorid. Disinfection with this material should be

supervised by a veterinarian or other person trained in the handling of

poisonous drugs and chemicals, as the bichlorid is a powerful, corrosive

poison. The mangers and the feed boxes, after drying, following spraying

with this material, should be washed out with hot water, as cattle are

especially susceptible to mercurial poisoning. The bichlorid solution

should be applied by means of a spray pump, as recommended for the

liquor cresolis compositus.

VACCINATION.

In recent years vaccination for the prevention of certain infectious

diseases has been successfully developed, and without a doubt the future

has a great deal in store for this phase of prevention. At the present

time vaccination has been found effective against blackleg, hog cholera,

anthrax, lockjaw, strangles, rabies, hemorrhagic septicemia, white

scours, etc. It is always essential, of course, that the products used

for the vaccination be pure and potent; also they should be employed

only with the advice of competent authorities and with proper care. The

biological products prepared for the cure and prevention of infections

are prepared by manufacturers who, in order to conduct an interstate

business, are required to obtain a license from the United States

Department of Agriculture for the manufacture of such preparations.

Since July 1, 1913, the Department of Agriculture, by an act of Congress

of March 4, 1913, has had control of the manufacture of biological

products for the treatment of domestic animals. The numerous complaints

which were received from time to time relative to the impotency of some

of the preparations, and also the fact that in some instances the use of

the products were directly responsible in causing outbreaks of disease,

made the necessity for such control obvious. This supervision is no

doubt of far-reaching importance, as it assures the users that the

preparations are reliable.

INFLUENZA.

_Synonyms._--Pinkeye, typhoid fever, epizooty, epihippic fever,

hepatic fever, bilious fever, etc.; flevre typhoide, grippe

(French); Pferdestaupe (German); gastro-enteritis of Vatel and

d'Arboval; febris erysipelatodes, Zundel; typhus of Delafond.

_Definition._--The term influenza is applied to a febrile, contagious,

infectious disease of horses, which is characterized by a blood

infection, with inflammation of the mucous membranes, which frequently

involves the lungs. Inflammatory complications also occur in the form of

swellings of the subcutis, tendons, and tendinous sheaths and laminae of

the feet. The causative agent has not been satisfactorily established.

One attack usually protects the animal from future ones of the same

disease, but not always. An apparently complete recovery is sometimes

followed by serious sequelae of the nervous and blood-vessel systems.

Under certain conditions of the atmosphere or from unknown causes, the

disease is very liable to assume an epizootic form, with tendency to

complications of especial organs, as, at one period, the lungs, at

another the intestines, etc.

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