_Amyloid_: horse: with exhausting diseases. Waxy secretion staining
mahogany brown with iodine. _Gangrene_: Swine. _Tubercle and glander
nodules._
This has been occasionally detected in the spleen of the horse. It is
usually connected with longstanding suppuration especially of bones,
with advanced tuberculosis or other exhausting disease. The organ is
usually greatly enlarged and the affected parts are firm, resistant and
swollen. On section it has not the soft friable or pulpy appearance of
the spleen, but an uniform waxy looking consistency, grayish or
sometimes stained with blood. On the application of a solution of iodine
and iodide of potassium the healthy splenic tissue is colored yellow,
while the amyloid portion becomes of a deep mahogany brown.