Largely secondary, from stomach, intestine, lymph glands, spleen,
pancreas; the hepatic tumor may be disproportionately large. In
_horse_: sarcoma rapidly growing soft, succulent, slow-growing,
fibrous, tough, stroma with round or spindle shaped cells and nuclei.
Symptoms: emaciation, icterus, enlarged liver, rounded tumors on
rectal examination. Melanoma, in old gray or white horses, with
similar formations elsewhere; not always malignant. Lymphadenoma.
Angioma. Carcinoma. Epithelioma, lesions, nodular masses, white or
grayish on section, and having firm stroma with alveoli filled with
varied cells with refrangent, deeply staining, large, multiple nuclei,
cancerous cachexia and variable hepatic disorder. In _cattle_:
sarcoma, adenoma, angioma, cystoma, carcinoma, epithelioma. In
_sheep_: adenoma, carcinoma. In _dog_: lipoma, sarcoma, encephaloid,
carcinoma, epithelioma. Wasting and emaciation, yellowish pallor,
temporal atrophy, ascites, liver enlargement, tender right
hypochondrium, dyspepsia, symptoms of primary deposits elsewhere.
The great quantity of blood which passes through the liver lays it open,
in a very decided way, to the implantation of germs and biological
morbid products. Hence tumors of the liver are largely secondary, the
primary ones being found mostly in the stomach, intestine, abdominal
lymph glands, spleen and pancreas. The primary neoplasm is often
comparatively small, while the hepatic one supplied with a great excess
of blood may be by far the most striking morbid lesion. The hepatic
tumors are mostly of the nature of angioma, sarcoma, melanoma, adenoma,
lipoma, cystoma, carcinoma, and epithelioma.