CHRONIC ARSENICAL POISONING.

This comes from continuous injudicious dosing with arsenic, or from the

condensing on the grass of the vapors from the smelting of ores

containing arsenic.

_Symptoms._ There is chronic indigestion, emaciation, hide-bound,

depilation, red or weeping eyes, chronic diarrhœa, suppression of milk

in cows, muscular weakness, paraplegia, soreness of the gums,

salivation.

The _lesions_ are essentially the same only less intense than in the

acute form. Hugo found in the intestines of poisoned animals a slimy,

serous, grayish white fluid, and a false membrane like a frog spawn

streaking the intestine. Later this may be dense like a diphtheritic

membrane. There was fatty degeneration of the liver and of the gall

bladder epithelium. Injection of the capillary vessels of the brain and

pia, and effusion into the ventricles and on the surface of the brain

were found in dogs.

_Elimination._ Arsenic is eliminated mainly in the urine, but also in

part in the bile and perspiration.

_Tests for Arsenic._ When taken in the solid form it may be found

undissolved on the gastric mucosa.

If burned on red hot charcoal or iron it gives out the odor of garlic.

Marsh’s test consists in evolving arseniureted hydrogen from zinc and

sulphuric acid to which a little of the suspected liquid has been added.

A flask is taken having a cork conveying two tubes, one a funnel

reaching nearly the bottom of the flask, and the other a delivery tube

of some length and provided with a chloride of calcium bulb, and at its

end turned up at right angles and drawn out to form a narrow orifice.

Pieces of zinc are placed in the bottom of the flask, and sulphuric acid

is poured upon these through the funnel. This causes the evolution of

hydrogen. The suspected liquid is now added, and the gas issuing from

the delivery tube having been lighted, a piece of cold white porcelain

is held above and a short distance from the flame. A dark metallic spot

of arsenic is obtained. The stain obtained by antimony differs in being

formed more closely to the flame, in volatilizing less rapidly under

heat, and in forming a black or orange instead of the canary yellow

sulphide when subjected to a stream of H_{2}S. with gentle heat.

Chloride of lime dissolves the arsenic stain but has no effect on the

antimonial one.

_Treatment._ Avoid the causes. Employ the antidotes in small doses once

or twice daily. Check the diarrhœa by mucilaginous agents, and nourish

the animals well.

Text book of veterinary medicine, Volume 2 (of 5) · 第 128 / 308 题