NICOTIANÆ FOLIA. D.

_Tobacco._

QUALITIES. _Odour_, strong, narcotic, and fœtid; _Taste_, bitter, and

extremely acrid; _Colour_, yellowish green, (its brown appearance is

artificial, being produced by the action of _sulphate of iron_.)

CHEMICAL COMPOSITION. Mucilage, albumen, gluten, extractive, a bitter

principle, _an essential oil_, nitrate of potass, which occasions its

deflagration, muriate of potass, and a peculiar proximate principle upon

which the properties of the plant are supposed to depend, and which has

therefore been named _Nicotin_.[658] Vauquelin considers it as

approaching the volatile oils in its properties; it is colourless, has

an acrid taste, and the peculiar smell of tobacco, and occasions violent

sneezing; with alcohol and water, it produces colourless solutions, from

which it is thrown down by tincture of galls. SOLUBILITY. Tobacco yields

its active matter both to water and spirit, but more perfectly to the

latter; long coction weakens its powers. An oil of tobacco of a most

powerful nature, may be obtained by distilling the leaves and separating

it from the water, on the top of which it will be found to float.[659]

MED. USES. Tobacco is endued with energetic poisonous properties,

producing generally a universal tremor which is rarely the result of

other poisons; the experiments of M. Orfila moreover demonstrate, that

the action of Tobacco is much more energetic when the soluble portion is

injected into the anus, than when it is applied to the cellular texture,

and for a still stronger reason, than when introduced into the stomach.

Mr. Brodie, from the result of a well devised experiment, has deduced

the conclusion that the infusion of Tobacco acts upon the heart,

occasioning syncope, through the medium of the nervous system. USES. As

a powerful sedative, it is sometimes valuable in medical practice; the

leaves, when applied in the form of a cataplasm to the pit of the

stomach, produce an emetic operation; (_Form. 67._) In cases of

obstinate constipation, depending upon violent spasmodic constriction,

or in _ileus_, or _incarcerated hernia_, clysters of the smoke of

Tobacco, or of an infusion made according to the London College, produce

almost immediate relief, (_Form. 26._); the practice is not unfrequently

attended with severe vomiting, extreme debility, and cold sweats,

circumstances which render its administration highly dangerous in cases

wherein the patient has been already exhausted by previous suffering. I

remember witnessing a lamentable instance of this truth some years ago;

a medical practitioner, after repeated trials to reduce a strangulated

hernia, injected an infusion of Tobacco, and shortly afterwards sent the

patient in a carriage to the Westminster Hospital, for the purpose of

undergoing the operation; but the unfortunate man arrived only a few

minutes before he expired. Clysters of Tobacco were some years ago

recommended in America, for the purpose of forwarding difficult

parturition, by inducing relaxation and consequent dilatation of the _os

uteri_, but the alarming symptoms which followed the single case in

which Tobacco was thus employed, ought, says _Dr. Merriman_, to prevent

a repetition of the experiment.[660] It was also formerly proposed to

inject infusions of Tobacco, for the purpose of recovering persons in a

state of _asphyxia_ from drowning; it is difficult to explain how such

an idea could have entered into the mind of the rational physiologist.

Smoking or chewing Tobacco has been also advised in cases of spasmodic

asthma, and as a general sedative to relieve suffering; in the process

of _smoking_, the oil is separated, and being rendered empyreumatic by

heat, it is thus applied to the fauces in its most active state. As a

diuretic it was successfully exhibited by Dr. Fowler, but as its

operation is uncertain and violent, and appears to be very analogous to

that of Digitalis, which is far more safe and manageable, it has been

very judiciously discarded from practice. The external application of

Tobacco in the form of cataplasm or infusion, has been applied to

several species of cutaneous disease, but even in this state it is

liable to exert its virulent effects. A woman applied to the heads of

three children afflicted with _tinea capitis_, a liniment consisting of

powdered tobacco and butter, soon after which they experienced vertigo,

violent vomiting, and fainting. (_Ephemerides des Curieux de la Nature_,

Dec. ii. An: i. p. 46.) A case has just occurred in this country of a

child whose death was occasioned by her having swallowed a portion of

half-smoked tobacco, which was taken from the pipe of her father, and in

which there no doubt existed a quantity of essential oil, which had been

separated by the act of smoking. It is a curious fact, that the juice of

the green leaves instantly cures the stinging of nettles.

ADULTERATIONS. When it exhales a fetid odour, we may infer that it has

been badly prepared, and not deprived of all its mucus; when pungent,

the presence of some deleterious drug is indicated: Cascarilla is very

usually added to impart a peculiar flavour; Nitre is also employed for

the sake of making it kindle more rapidly, and to impress a lively

sensation on the tongue; its vapour is of course very injurious to the

lungs: its presence may be detected by treating a suspected sample with

hot water, and after filtering the solution through charcoal, setting it

aside in order that it may yield its crystals by evaporation. Traces of

_Lead_, _Copper_, or _Antimony_, may be discovered by boiling the

Tobacco in strong vinegar, and, after filtering it as before, by

assaying it with appropriate tests. _Black Hellebore_, _Alum_, _Sugar_,

and _Corrosive sublimate_ are amongst the more usual sophistications.

_Dried Dock_ leaves are also sometimes substituted. OFFICINAL PREP:

_Infus: Tabacci_. L. _Vinum Nicotian: Tabac:_ E.

SNUFF. This well known errhine is prepared from the dried leaves of

Tobacco; in its manufacture however, numerous additions are made which

are kept secret. _Salt_ is added for the purpose of increasing its

weight; _Urine_, Muriate of ammonia, and powdered Glass, to heighten its

acrimony. The varied flavour of different _Snuffs_ is owing to the leaf

being in greater or less perfection; or to its having undergone some

degree of fermentation; thus, for instance, the _Macouba Snuff_ of

Martinique is principally indebted for its acknowledged superiority to

the fermentation which the Tobacco undergoes, from being moistened with

the best cane juice; other kinds are excited into fermentation by

moistening them with melasses and water.

Snuff possesses all the powers of Tobacco; the celebrated Santeuil

experienced vomiting and horrible pains, amidst which he expired, in

consequence of having drank a glass of wine, into which had been put

some Spanish snuff.[661]

Pharmacologia Fourth American, from the Seventh London Edition · 第 540 / 782 题