HELLEBORI NIGRI RADIX. L.E.D.

_The Root of Black Hellebore._ _Melampodium._[518]

_Christmas Rose._

QUALITIES. The fibres of the root are the parts employed; they are about

the thickness of a straw, corrugated, externally of a deep dark colour,

hence the epithet _black_; internally white, or of a yellowish hue.

_Odour_, unpleasant; _Taste_, bitter and acrid. CHEMICAL COMPOSITION. An

analysis of this root has lately been effected by M. M. Feneulle and

Capron, from which it appears that its active principle, unlike that of

the White Hellebore (_Veratrum_) is not an alkali; the following

substances enter into its composition, viz. 1. A Volatile Oil.—2. A

Fatty matter.—3. A Resin.—4. Wax.—5. A Volatile Acid.—6. A bitter

principle.—7. Mucus.—8. Alumina.—9. Gallate of Potass.—10. Acidulous

Gallate of Lime.—11. A Salt, with an Ammoniacal base. SOLUBILITY. Both

water and alcohol extract its virtues, but the spirituous solution is

the most active; long coction diminishes its powers, hence the watery

extract acts more mildly than the root. MEDICINAL USES. This is one of

the most ancient articles of the materia medica. Ctesias, who lived in

the time of Plato, and anterior to Hippocrates, speaks of it as a

medicine of important virtues. By the Greek and Roman physicians it was

highly esteemed as a remedy in Mania (_see p. 8._) The extraordinary

cures performed at the island of Anticyrus, famous for its Hellebore,

are celebrated by the poets and historians of antiquity. It is a drastic

cathartic, and may prove therefore emmenagogue, and hydragogue, but in

this country, its reputation has been destroyed by the decided manner in

which Dr. Cullen reprobated its use. FORMS OF EXHIBITION. It is seldom

given in substance, but in the form of tincture or extract; or in that

of decoction, made with two drachms of the root to a pint of water. DOSE

of the powdered root, grs. x to ℈j; of the decoction, f℥j. OFFICINAL

PREPARATIONS. _Tinct. Hellebori Nigri._ L.E.D. _Extractum Hellebori

Nigri._ E.D. ADULTERATIONS. The roots of the poisonous aconites are

often fraudulently substituted; this is easily discovered, for the

aconite is lighter coloured than the palest specimens of black

hellebore; it is safe therefore to choose the darkest.

Pharmacologia Fourth American, from the Seventh London Edition · 第 349 / 782 题