III. OF MEDICINES WHICH OPERATE _mechanically_.

_a._ _By imparting vigour to the respiratory muscles, engaged in the act

of expectorating._

It must be admitted that, to a certain extent, expectoration is a

voluntary operation, connected with the action of a variety of muscles,

which in a state of extreme debility are not easily excited into action:

every practitioner must have noticed this fact during the treatment of

the coughs of exhausted patients, and have witnessed the distress

necessarily arising from it; in this condition, the exhibition of a

stimulant may so far renew the exhausted excitability of these organs,

as to enable them to undergo the necessary exertions.

_b._ _By compressing the thoracic viscera, through the operation of an

emetic._

The beneficial results which frequently attend the concussion of an

emetic, in cases of mucous accumulations in the lungs, are too well

known and understood to require much elucidation: in the act of vomiting

the thoracic viscera are violently compressed, the neighbouring muscles

are also called into strong action, and both expiration and inspiration

are thus rendered more forcible, and the expulsion of mucus from the

cavity of the lungs necessarily accomplished.

The safety and expediency of such a resource must, however, in each

particular case be left to the discretion of the medical practitioner.

Besides the remedies above enumerated, there are some others which

afford relief in certain coughs, and have therefore in popular medicine,

been considered as _Expectorants_; but their operation, if they exert

any, is to be explained upon principles altogether different from that

of facilitating expectoration, and will more properly fall under the

head of _Demulcents_.

Atmospheric changes, in relation to moisture and dryness, deserve some

notice before we conclude the history of expectorant agents: the subject

teems with curious and important facts, and the advantages which the

asthmatic patient derives from such changes merit farther investigation.

That the lungs are constantly giving off aqueous vapour is made evident

by condensing the expired air on a cold surface of glass or metal; and

it is easy to imagine that when the atmosphere is saturated with

moisture, its power of conducting off this vapour will be proportionably

diminished, and that an accumulation of fluid may thus take place in the

lungs; on the other hand, we may suppose the air to be so dry as to have

an increased capacity for moisture, and to carry off the expired vapour

with preternatural avidity; in either of these cases, the excretions

from the lungs will be materially influenced, whether to the benefit or

disadvantage of the patient will depend, in each particular instance,

upon the nature of the disease under which he suffers. I have known a

person who could breathe with more freedom in the thick fogs of the

metropolis than in the pure air of a mountainous region, and it would

not be difficult to adduce many examples in illustration of a

diametrically opposite constitution of the pulmonary organs.

From the same cause we may frequently observe remarkable changes occur

in the character of a cough, at the breaking up of a frost; in some

cases the expectoration will be checked, and in others promoted by a

sudden change from a dry to a moist atmosphere. Can a more instructive

illustration be offered of that important fact, which I have been

labouring in every page to impress upon the mind of the young

practitioner, that, _remedies are only relative agents_?

In the course of considerable experience in the treatment of pulmonary

complaints, and in the influence of climate and seasons upon them, I

have repeatedly observed the rapid transition from moisture to dryness

to occasion very remarkable effects upon the disease; and I much

question whether an attention to such a condition of the atmosphere does

not deserve as much consideration in the election of a suitable place of

residence for such invalids, as the more obvious circumstance of

temperature. I have been long in the habit of recommending to persons

confined in artificially warmed apartments, to evaporate a certain

portion of water, whenever the external air has become excessively dry

by the prevalence of the north-east winds, which so frequently infest

this island during the months of Spring; and the most marked advantage

has attended the practice. But in such cases the practitioner must ever

be guided by the symptoms of each particular case; it would be worse

than useless to lay down any general precept for his guidance. We cannot

then be surprised that such a difference of opinion should exist amongst

practitioners of equal eminence, respecting the influence of a marine

atmosphere; some advocating its advantages to the pulmonary invalid, and

others maintaining with equal confidence the injurious tendency of such

localities; each party appeals to _experience_ in justification of his

opinion, and with equal candour and justice; but the cases from the

results of which the medical inference has been drawn, however parallel

they may have appeared, differed in those essential points to which we

have alluded, and upon which the question of climate would seem to turn.

There is another circumstance connected with the subject of atmospheric

moisture which it is also essential to remember,—that the air gains a

considerable increase in its power of conducting caloric, by becoming

saturated with aqueous vapour; thus, when a thaw takes place, and the

thermometer rises a few degrees above 32°, the air, instead of

impressing us with the sensation of increased temperature, actually

appears much colder.

Pharmacologia Fourth American, from the Seventh London Edition · 第 95 / 782 题