J. M. H. M.

DERMATITIS FRAMBŒSIFORMIS. F. SAUERBERGER (_Archiv f. Derm. u.

Syph._, October, 1904, lxxii, p. 3).

In this contribution the writer describes an unusual case which occurred

in Professor Janovsky’s clinic at Prague. The patient was a coal-miner,

aged 18 years. At the age of 14 he began work in a mine and soon

afterwards he suffered from a severe attack of furunculosis, which

persisted for a year. As it got steadily worse he had to leave his work

for a time. When he was able to work again he got employment in another

mine. After some time he went to the original mine and the furunculosis

returned rapidly and he was again compelled to leave work. He blamed bad

drinking-water as the cause of it. Several other miners in the same pit

were similarly affected and among them was the patient’s father. Soon

after leaving work for the second time the pustular lesions began to be

replaced by raised papillomatous masses which were especially

well-marked about the face and neck. The eyelids, forehead, tip of the

nose, nasal orifice, lips, chin, and left side of the cheek became

covered with crusted papillomatous lesions. A few similar lesions

developed on the body in the inguinal regions, and both the cervical and

inguinal glands were enlarged. A microscopical examination of one of the

lesions showed a proliferation of the interpapillary processes, and a

dense cellular infiltration in the papillary and sub-papillary layers,

consisting chiefly of leucocytes and mast-cells and dilatation of the

capillaries. The lesions did not react well to local treatment, but

eventually with tonics and by persevering with local remedies a cure

resulted. There was no history or evidence of syphilis. The disease was

similar in many respects to tropical frambœsia or yaws, and corresponded

closely to a case which Lewin described as sporadic frambœsia.

The British Journal of Dermatology, April 1905 · 第 9 / 20 题