4. Excessive obesity with tendency to weakness and anaemia.

5. Melancholia functional insanity, where improvement has taken place up

to a certain point and then remains so.

6. Defective secretion of milk during lactation when connected with

reappearance of menses. _Thyroid_ will suppress the latter and increase

and enrich the milk.

7. In fractures of the bones in which consolidation does not promptly

occur.

8. Hypertrophy of cicatricial tissue resembling keloid, possibly true

keloid.

_Doses:_ Either the fresh gland of the sheep prepared like food or the

extract, or in the dessicated state, of the latter may be given from 2-3

grs., or more or less, once a day (at night) or oftener.

The _Thyroid_ is _contra-indicated_ in tuberculous persons, as they are

apt to lose quickly in weight, over two pounds in twenty-four hours.

Rheumatic and anaemic symptoms are more frequently aggravated than

improved.

As the _Thyroid_ is a powerful remedy, the following should be always

remembered:

There is a decided difference with regard to individual toleration, some

are very susceptible.

The pulse should be watched regarding frequency and quality. The least

effort or exertion will increase it even to 160, hence some cases should

be kept in bed or at least very quiet and tranquil even for a time after

the remedy has been discontinued. Deaths have taken place after a few

days' treatment.

If _Thyroid_ is not taken for myxoedema the patient should be weighed

at least every two weeks, and if pathogenetic symptoms, called

thyroidism, appear the remedy should be discontinued or reduced.

If softening of the bones has been caused it may be necessary to

restrict the use of the legs or to use splints.

_Thyroid_ seems to have a cumulative effect.

In many cases a liberal diet should be prescribed to avoid injurious

consequences.

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