8. Menses profuse, prolonged or more frequent, rarely amenorrhoea.

9. Increased activity of the mucous membrane, kidneys and skin, which

becomes moist and oily, sometimes exfoliation of the epidermis.

10. Rapid growth of the skeleton in the young with softening and bending

of those bones which have to bear weight.

11. A disease closely resembling exophthalmic goitre. A cataleptic

improved under large doses of _Thyroid_, but when the dose of 75 grs. a

day was reached symptoms like those of exophthalmic goitre developed

with a pulse of 160, but no glandular swelling. When the _Thyroid_ was

discontinued the catalepsy grew worse, the exophthalmic goitre better;

when resumed the catalepsy better, the exophthalmic goitre worse.

A patient, while under _Thyroid_ treatment for myxoedema, took,

through a misunderstanding, in eleven days nearly 3 ounces of the

dessicated _Thyroid_, whereupon tachycardia, pyrexia, insomnia, tremor

of the limbs, polyuria, albuminuria, and glucosuria, in short, a disease

similar to exophthalmic goitre developed.

_Thyroid_ has been _used_ with benefit in the following _diseases_:

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