LOCAL ANÆSTHESIA BY THE HYDROCHLORATE OF COCAINE.

By R. J. LEVIS, M.D., Surgeon to the Pennsylvania Hospital and to the

Jefferson Medical College Hospital.

The notes of a few cases of the use of the hydrochlorate of cocaine

will illustrate its perfect efficiency in some and its apparent

inertness in others, and may help toward its proper application and

general appreciation.

In a double extraction of hard cataract there was no pain produced by

the graspings of the conjunctiva in the fixation of the eyes, in the

corneal incisions, and in the iridectomies.

A 4 per centum solution was freely brushed over the entire conjunctival

surface three times, at intervals of ten minutes, and the operations

were commenced in forty minutes after the first application. No

irritation was produced, and the only sensation described was that

of "numbness and hardness." The entire conjunctival surface seemed

insensible to repeated pinching with the fixation forceps.

In a single extraction of hard cataract a 4 per centum solution was

brushed over the ocular and palpebral conjunctiva, with the eyelids

freely everted. Three applications were made at intervals of ten

minutes, and the operation was performed at the lapse of twenty-five

minutes. The patient asserted decidedly that she felt no pain whatever.

Preparatory to the operation for uterine procidentia and rectocele, the

vaginal and labial mucous surface was wiped dry, and a 4 per centum

solution of the hydrochlorate of cocaine was thoroughly brushed over

it. The sensitiveness was tested at three intervals of ten minutes

each, and the application was repeated three times. There appeared

to be at no time any decided loss of painful sensibility, and the

operation was finally performed under the anæsthesia of sulphuric ether.

For the removal of a rather large tarsal tumor, the ocular and

palpebral conjunctiva and the exterior of the eyelids were brushed with

the solution as previously used, at intervals of ten minutes, and the

excision was performed at the lapse of forty minutes. The operation

seemed to be as painful to the patient as if performed without an

attempt at anæsthesia.

For the operation for lachrymal obstruction the application was made in

the same manner and at the same intervals. The slitting of the punctum

and caniculus gave no pain, but the passage of the dilating probe down

the lachrymal canal seemed to produce some uneasiness.

Prior to applying nitric acid as a caustic to a syphilitic ulcer on the

tongue, the same manner and number of applications were repeated, the

tongue having been wiped dry and held protruding between the teeth. No

pain was produced on the thoroughly benumbed tongue.--_Med. News._

Scientific American Supplement, No. 467, December 13, 1884 · 第 39 / 76 题