PARANGI--A NEWLY DESCRIBED DISEASE.

A peculiar contagious disease, called framboesia, or the yaws, has

long been known to exist in Africa, the West Indies, and the northern

parts of the British Islands. It is chronic in character, and is

distinguished by the development of raspberry-like tumors of

granulation tissue on different parts of the body.

A disease of a somewhat similar, but severer type, has for many years

prevailed in Ceylon. Even less was known of this affection than of its

supposed congener, until a recent careful report upon the subject by

Mr. W.R. Kinsey, principal civil medical officer of Ceylon.

The disease in question is called "parangi," and is defined by Mr.

Kinsey (_British Medical Journal_) as a specific disease, produced by

such causes as lead to debilitation of the system; propagated by

contagion, generally through an abrasion or sore, but sometimes by

simple contact with a sound surface; marked by an ill-defined period

of incubation, followed by certain premonitory symptoms referable to

the general system, then by the evolution of successive crops of a

characteristic eruption, which pass on in weakly subjects into

unhealthy and spreading ulcers whose cicatrices are very prone to

contraction; running a definite course; attacking all ages, and

amenable to appropriate treatment.

The disease seems to develop especially in places where the water

supply, which in Ceylon is kept in tanks, is insufficient or poor. The

bad food, dirty habits, and generally unhygienic mode of life of the

people, help on the action of the disease.

Parangi, when once developed, spreads generally by contagion from the

discharges of the eruptions and ulcers. The natural secretions do not

convey the poison. The disease may be inherited also.

In the clinical history of the disease there are, according to Mr.

Kinsey, four stages. The first is that of incubation. It lasts from

two weeks to two months. A sore will be found somewhere upon the body

at this time, generally over some bony prominence. The second is the

stage of invasion, and is characterized by the development of slight

fever, malaise, dull pains in the joints. As this stage comes on the

initial sore heals. This second stage lasts only from two to seven

days, and ends with an eruption which ushers in the third stage. The

eruption appears in successive crops, the first often showing itself

on the face, the next on the body, and the last on the extremities.

This eruptive stage of the disease continues for several weeks or

months, and it ends either in convalescence or the onset of a train of

sequelæ, which may prolong the disease for years.

Parangi may attack any one, though the poorly fed and housed are more

susceptible. One attack seems to confer immunity from another.

Although some of the sequelæ of the disease are most painful, yet

death does not often directly result from them, nor is parangi itself

a fatal disease. Persons who have had parangi and passed safely

through it, are not left in impaired health at all, but often live to

an old age.

The similarity of the disease, in its clinical history, to syphilis,

is striking. Mr. Kinsey, however, considers it, as we have stated,

allied to, if not identical with framboesia.--_Medical Record._

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Scientific American Supplement, No. 315, January 14, 1882 · 第 85 / 122 题