Three drachms of recent pus, derived from the same patient as in the
last experiments, were injected into the jugular vein of a small
emaciated unhealthy dog. After the expiration of three minutes, there
was an abundant evacuation of urine, followed by continued vomiting,
and repeated ineffectual efforts to pass fæces. For nearly a quarter
of an hour, there was a kind of emprosthotonos, rigidity of the limbs,
and a death-like condition. Subsequently, fresh vomiting ensued, with
very fetid liquid evacuations, which were followed by apparent relief;
soon after, however, long continued tenesmus made its appearance, and
terminated in death, five hours after the injection of the pus. On
opening the body, the mucous membrane of the intestines was found red,
swollen, and inflamed, especially in the colon and rectum.