CAUSES OF INSANITY.

When patients are admitted into Bethlem Hospital, an enquiry is always

made of the friends who accompany them, respecting the cause supposed to

have occasioned their insanity.

It will be readily conceived, that there must be great uncertainty

attending the information we are able to procure upon this head: and even

from the most accurate accounts, it would be difficult to pronounce, that

the circumstances which are related to us, have actually produced the

effect. The friends and relatives of patients are, upon many occasions,

very delicate concerning this point, and cautious of exposing their

frailties or immoral habits: and when the disease is connected with the

family, they are oftentimes still more reserved in disclosing the truth.

Fully aware of the incorrect statement, frequently made concerning these

causes, I have been at no inconsiderable pains to correct or confirm the

first information, by subsequent enquiries.

The causes which I have been enabled most certainly to ascertain, may be

divided into PHYSICAL and MORAL.[14]

Under the first, are comprehended repeated intoxication: blows received

upon the head; fever, particularly when attended with delirium; mercury,

largely and injudiciously administered; cutaneous eruptions repelled, and

the suppression of periodical or occasional discharges and secretions;

hereditary disposition, and paralytic affections.

By the second class of causes, which have been termed _moral_, are meant

those which are supposed to originate in the mind, or which are more

immediately applied to it. Such are, the long endurance of grief; ardent

and ungratified desires; religious terror; the disappointment of pride;

sudden fright; fits of anger; prosperity humbled by misfortunes:[15] in

short, the frequent and uncurbed indulgence of any passion or emotion, and

any sudden or violent affection of the mind.

There are, doubtless, many other causes of both classes, which may tend to

produce this disease. Those which have been stated, are such as I am most

familiar with; or, to speak more accurately, such are the circumstances

most generally found to have preceded this affection.

It is an old opinion, and continues still to prevail, that maniacs are

influenced by the changes of the moon. In the fourth chapter of St.

Matthew's Gospel, verse 24, we find the word "[Greek: Seleniaxomenous]"

which is rendered in the English version, "those which were lunatic."

Notwithstanding the notion of being moon-struck might prevail among the

ignorant people of Galilee, yet Hippocrates, a philosopher, and correct

observer of natural phaenomena, does not appear to have placed any faith in

this planetary influence. Although the Romans were infected with this

popular tradition, as may be seen in the following passage of the Art of

Poetry,

"Ut mala quem scabies aut morbus regius urget,

Aut fanaticus error, et IRACUNDA DIANA

Vesanum tetigisse timent fugiuntque poetam,

Qui sapiunt:"--

yet Celsus did not consider the operation of the moon on the human

intellect sufficiently well founded to admit it into his medical work.

Not a word on this subject is mentioned in the eighteenth chapter of his

third book, which particularly treats of Insanity, "_De tribus insaniae

generibus_;" it is true that, in the fourth chapter of the first book,

which speaks "_De his quibus caput infirmum est_," he says "Cui caput

infirmum est, is si bene concoxit, leniter perfricare id mane manibus suis

debet; nunquam id, si fieri potest, veste velare; aut ad cutem tondere:

utileque lunam vitare, maximeque ante ipsum lunae solisque concursum." By

the _infirmum caput_, Celsus does not mean madness, as may be clearly seen

by perusing the chapter: the weakness of intellect, which frequently

continues after fever, or other violent diseases, is evidently his

meaning; but Dr. Cox has quoted the above passage, to prove that Celsus

was impressed with the truth of this vulgar opinion. He says, "This idea

of lunar influence, in _maniacal complaints_, was handed down to us by

our medical forefathers, and is still very generally adopted."

It is most probable that this idea of planetary regency, however it might

have arisen, or to whatever extent it may have been credited, received in

the Arabian school, the stamp by which its currency has been subsequently

maintained. For the revival and dispersion of ancient medical knowledge,

we are confessedly under considerable obligations to the Arabians;[16] and

more especially for the incorporation of astrology, magic and alchymy,

with medicine.

Popular superstitions and national proverbs, are seldom without some

foundation; and with respect to the present, it may be observed, that if

it were not in some degree rooted in fact, and trained up by observation,

it would become difficult to ascertain how such an opinion came to be

adopted; and this investigation is rendered still more important from the

consideration, that the existing law in this country, respecting insane

persons, has been established on the supposed prevalence of this lunar

regulation. A commission is issued, de _lunatico_ inquirendo, and the

commissioners sitting for that purpose, are particular in their enquiries,

whether the patient enjoys lucid intervals. The term _lucid interval_ has

been properly connected with the word _lunacy_; for, if the patient, as

they supposed, became insane at particular changes of the moon, the

inference was natural, that in the intervening spaces of time he would

become rational.

It is more than probable, that the origin of this supposition of the lunar

influence may be traced to the following circumstances. The period of the

return of the moon, and of regular menstruation in women, is four weeks;

and the terms which designate them, have been imposed from the period of

time in which both are compleated. Insanity and epilepsy are often

connected with menstruation, and suffer an exacerbation of their paroxysms

at the period when this discharge happens, or ought to take place. If,

therefore, the period of menstruation in an insane woman should occur at

the full of the moon, and her mind should then be more violently

disturbed, the recurrence of the same state may be naturally expected at

the next full moon. This is a necessary coincidence, and should be

discriminated from effect. But such has been the prevalence of this

opinion, that when patients have been brought to Bethlem hospital,

especially those from the country, their friends have generally stated

them to be worse at some particular change of the moon, and of the

necessity they were under, at those times, to have recourse to a severer

coercion. Indeed, I have understood from some of these _lunatics_, who

have recovered, that the overseer or master of the work-house himself has

frequently been so much under the dominion of this planet, and keeping

steadily in mind the old maxim, _venienti occurrite morbo_, that, without

waiting for any display of increased turbulence on the part of the

patient, he has bound, chained, flogged, and deprived these miserable

people of food, according as he discovered the moon's age by the almanack.

To ascertain how far this opinion was founded in fact, I kept, during more

than two years, an exact register, but without finding, in any instance,

that the aberrations of the human intellect corresponded with, or were

influenced by, the vicissitudes of this luminary.

As insane persons, especially those in a furious state, are but little

disposed to sleep, even under the most favourable circumstances, they will

be still less so, when the moon shines brightly into their apartments.

It has also been considered, that intellectual labour frequently becomes a

cause of insanity; that those, who are in the habit of exercising the

faculty of thought, for the perfection and preservation of the reason of

others, are thereby in danger of losing their own. We hear much of this,

from those who have copiously treated of this disease, without the toil of

practical remark; whose heads become bewildered by the gentlest exercise,

and to whom the recreation of thinking becomes the exciting cause of

stupidity or delirium. These persons enumerate, among the exciting causes

of delirium, "Too great, or too long continued exertion of the mental

faculties, as in the delirium which often succeeds long continued and

abstract calculation; and the deliria to which men of genius are

peculiarly subject."

The mind of every man is capable of a definite quantity of exertion to

good effect; all endeavours, beyond that point, are impotent and

perplexing. The attention is capable of being fixed to a certain extent,

and, when that begins to deviate, all continuance is time lost. It is

certain that, by habit, this power may be much increased; and, by frequent

exercise, that, which at first excited fatigue, may be continued with

facility and pleasure. What species of delirium is that, which succeeds

long continued and abstract calculation? Newton lived to the age of 85

years, Leibnitz to 70, and Euler to a more advanced period, yet their

several biographers have neglected to inform us, that their studies were

checquered with delirious fermentations. The mathematicians of the present

day (and there are many of distinguished eminence) would conceive it no

compliment to suppose that they retired from their labours with addled

brains, and that writers of books on insanity should impute to them

miseries which they never experienced.

It is curious to remark, in looking over a biographical chart, that

mathematicians and natural philosophers have in general attained a

considerable age; so that long continued and abstract calculation, or

correct thinking upon any subject does not appear, with all these

delirious visitations, to shorten the duration of human life. What is

meant by the deliria, to which men of genius are peculiarly subject, I am

unable, from a want of sufficient genius and delirium, to comprehend.

It is well understood, that a want of rational employment is a very

successful mode of courting delirium; that an indulgence in those reveries

which keep the imagination on the wing, and imprison the understanding, is

likely to promote it: and it must be owned, that the same effect has often

been produced, where vanity or ambition has urged minds, puny by nature,

and undrilled in intellectual exercises, to attempt to grasp that which

they were unable to embrace. This may be illustrated by the following

case.

A young gentleman of slender capacity, and very moderate education, at the

age of nineteen, was placed in a merchant's counting house, where he

continued for two years diligently, though slowly, to perform the duties

of the office. Coming at this time into the possession of considerable

property, and perhaps, aware of the uncultivated state of his own mind, he

very laudably determined to improve it. He frequented the society of

persons esteemed learned and eminent in their different professions, and

became much delighted with their conversation; but at the same time

sensible that he was unable to contribute to the discourse. He resolved to

become a severe student, and for this purpose purchased an immense

quantity of books on most subjects of literature and science. History

commenced the career of his enquiries: Rollin, Gibbon, Hume and Robertson

were anxiously and rapidly perused; but he never paused to consider, or to

connect dates and circumstances, so that these excellent authors, after he

had waded through them, left scarcely an impression on his mind. Chemistry

next engaged his attention, and on this subject, he pored over many

volumes with little advantage: the terms proved a source of embarrassment,

and he made no experiments. In a hasty succession, the ancient languages,

antiquities, etymology, agriculture, and moral philosophy, occupied his

mind. About eight hours were daily devoted to reading. Somewhat more than

two years were consumed in this employment, which had distracted his mind,

without conferring any positive knowledge.

His friends and acquaintances now began to perceive a considerable

alteration in his temper; though naturally diffident, he had assumed a

high degree of literary importance, and plumed himself on the extent of

his learning. Before this excessive, but ill-directed application, he was

a strict relator of the truth, but he now found a convenience in supplying

by fancy, that, which the indigence of his memory was unable to afford.

Shortly he began to complain that he could not sleep, and that the long

night was passed in shifting from side to side.

"Lasso, ch'n van te chiamo, et queste oscure,

Et gelide ombre in van lusingo: o piume

D'asprezza colme: o notti acerbe, et dure."

_Gio: Della Casa._

Fever succeeded, accompanied with delirium in the evening. By quietness,

and the ordinary remedies, these symptoms were removed; but he was left in

a state of extreme weakness. As he recovered from this, his habits became

materially altered: he would continue to lie in bed for several days,

after which, he would suddenly rise and walk a number of miles. Personal

cleanliness, and dress were entirely neglected: sometimes he would fast

for two or three days, and then eat voraciously. Afterwards he became

suspicious that poison had been mixed with his food. It was found

necessary to confine him, from having attempted to castrate himself: this

he afterwards effected in a very complete manner, and continues a maniac

to the present time.

Few persons, I believe, will be disposed to consider the above case, as an

instance of insanity succeeding to a laborious exercise of the

intellectual faculties. It is true, he was busied with books: but this

occupation could not have strained his mind, for he appears neither to

have comprehended, nor retained any of the objects of his pursuit.

_Hereditary Disposition._

"Ut male posuimus initia sic cetera sequuntur."--_Cicero._

"Whatever was in the womb imperfect, as to her proper work, comes very

rarely, or never at all, to perfection afterwards."--_Harrington's

Works, p. 177._

Considerable diversity of opinion has prevailed, whether insanity be

hereditary or not; and much has been said on both sides of this question.

Great ingenuity has been exerted to prove that this disease is accidental,

or that there are sufficient causes to account for its occurrence, without

supposing it one of those calamities that "_flesh is heir to_." It has

been argued, that, if the disease were hereditary, it ought uniformly to

be so, and that the offspring of a mad parent should necessarily become

insane.

All theories and reasonings appear to be good for as much as they prove;

and if the term _hereditary_ be employed with a degree of strictness, so

as to denote certain and infallible transmission, such inevitable descent

cannot be defended. Several instances have come under my observation where

the children of an insane parent have not hitherto been affected with

madness, and some have died early in life, without having experienced any

derangement of mind. More time is therefore required.

All observations concur in acknowledging that there are many circumstances

in which children resemble their parents. It is very common to see them

resemble one of their parents in countenance, and when there are several

children, some shall bear the likeness of the father and others of the

mother. Children often possess the make and fashion of the body, peculiar

to one or other of their parents, together with their gait and voice; but

that which has surprized me most is the resemblance of the hand-writing.

If a parent had taught his son to write, it might be expected that a

considerable similarity would be detected; but in general the fact appears

to be otherwise, for it seldom happens that the scholars, though

constantly imitating the copy of the master, write at all like him, or

like each other. In a few instances I have noticed a correct resemblance

between the hand-writing of the father and son, where the former died

before the latter had been taught the use of the pen, and who probably

never saw the hand-writing of his father. The transmission of personal

deformities is equally curious. I am acquainted with a person in this

town, whose middle and ring finger are united, and act as one; all the

children of this man carry the same defect. A toenail, particularly

twisted, has been traced through three generations, on the same foot and

toe. Abundant instances might be adduced on this subject; there is

scarcely a family which cannot produce something in confirmation; and if

to these circumstances in the human species, were to be added the

experiments which have been made on the breeding of cattle, perhaps

little doubt would remain.

The reasoners against the transmission of madness urge, that, if the

contrary were true, we should by this time have detected the rule or law

by which nature acts, and that we should have been able to

determine,--First, whether the disorder descended to the male or female

children accordingly as the father or mother was affected.--Secondly,

which of the parents is most capable of transmitting the

disease?--Thirdly, what alternations in the succession take place, does it

shift from the male to the female line, and, does it miss a generation,

and afterwards return?

These, and a multitude of other queries, might be proposed; I believe much

faster than they could be answered. Nature appears to delight in producing

new varieties, perhaps less in man than in other animals, and still less

in the animal than in the vegetable kingdom. Before these subtile

reasoners expect, from those who maintain that madness generally descends

from the parent to the offspring, a developement of the laws by which

Nature acts, it would be convenient first to settle whether in this matter

she be under the dominion of any law whatever.

The investigation of the hereditary tendency of madness is an object of

the utmost importance, both in a legal and moral point of view. Parents

and guardians, in the disposal, or direction of the choice of their

children in marriage, should be informed, that an alliance with a family,

where insanity has prevailed, ought to be prohibited.

Having directed some attention to enquiries of this nature, I am enabled

truly to state, that, where one of the parents have been insane, it is

more than probable that the offsprings will be similarly affected.

Madness has many colours, and colours have many hues; actual madness is a

severe calamity, yet experience has pointed out the treatment, and the law

has permitted the imposition of the necessary restraint: but it very

frequently occurs that the descendants from an insane stock, although they

do not exhibit the broad features of madness, shall yet discover

propensities, equally disqualifying for the purposes of life, and

destructive of social happiness.

The slighter shades of this disease include eccentricity, low spirits, and

oftentimes a fatal tendency to immoral habits, notwithstanding the

inculcation of the most correct precepts, and the force of virtuous

example.

In illustration of the fact, that the offsprings of insane persons are,

_ceteris paribus_, more liable to be affected with madness than those

whose parents have been of sound minds; it was my intention to have

constructed a table, whereon might be seen the probably direct course of

this disease, and also its collateral bearings: but difficulties have

arisen. It appeared, on consideration, improper to attempt precision with

that which was variable, and as yet unsettled; I have therefore been

content to select a few histories from my book of notes, and to exhibit

them in the rude state in which they were set down.

_1st._--R. G. His grandfather was mad, but there was no insanity in his

grandmother's family. His father was occasionally melancholic, and once

had a raving paroxysm. His mother's family was sane. His father's brother

died insane. R. G. has a brother and five sisters; his brother has been

confined in St. Luke's, and is occasionally in a low spirited state. All

his sisters have been insane; with the three youngest the disease came on

after delivery.

_2d._--M. M. Her grandmother was insane and destroyed herself. Her father

was mad for many years, but after the birth of all his children. M. M. has

two brothers and a sister; both her brothers have been insane; the sister

has never been so affected, but was a person of loose character. The

insanity of M. M. was connected with her menstruation; after its cessation

she recovered, although she had been confined more than sixteen years.

_3d._--M. H. Her father had been several times insane; her mother was

likewise so affected a few months before her death. Afterwards her father

married a woman perfectly sane, by whom he had three children, two female

and a male; both the females are melancholic, the male was a vicious

character, and has been transported. M. H. has had ten children, three

have died with convulsions, the eldest, a girl, is epileptic.

_4th._--T. B. His mother became insane soon after being delivered of him,

and at intervals has continued so ever since. He has a brother who became

furiously mad at the age of twenty, and afterwards recovered. T. B.'s

disorder came on at the age of twenty-six.

_5th._--S. F. Her father's mother was insane, and confined in the

hospital. Her father never discovered any symptoms of insanity, and her

mother was perfectly sane. Her only sister (she had no brothers) was mad

about five years ago, and recovered. S. F. has been twice in the hospital.

_6th._--P. W. After the best enquiries it does not appear that her father

or mother ever experienced any attack of madness or melancholy. P. W.'s

disorder commenced shortly after the delivery of a child. She has three

sisters, the eldest has never been married, and has hitherto continued of

sound mind. The two younger have been mothers, and in both insanity has

supervened on childbearing.

_7th._--J. A. H. His father's father was insane, and his father was also

disordered, and destroyed himself. His mother was of sound mind. J. A. H.

became insane at the age of twenty-three. He has two sisters, the elder

has once been confined for insanity, the younger is of weak intellects,

nearly approaching to ideotism.

_8th._--M. D. Her mother was insane and died so. M. D. continued of sane

mind until she had attained the age of fifty-seven, when she became

furiously maniacal; her only daughter, eighteen years of age, was attacked

with mania during the time her mother was confined.

_9th._--G. F. His mother was melancholic during the time she was pregnant

with him, and never afterwards completely recovered. She had five children

previously to this melancholic attack, who have hitherto continued of

sound mind. She bore another son after G. F. who is extremely flighty and

unmanageable. G. F. was attacked with madness at the age of nineteen, and

died apoplectic, from the violence and continued fury of his disorder.

_10th._--M. T. Her mother was of sound mind. Her father was in a

melancholic state for two years, before she was born, but this was

afterwards dissipated by active employment. M. T. has two brothers,

younger than herself, who have been attacked with insanity, neither of

whom have recovered. She has two sisters, some years older than herself,

these have never been deranged. M. T. has had nine children. The three

first have been melancholic. The youngest, at the age of five years, used

to imagine she saw persons in the room covered with blood, and other

horrible objects, she afterwards became epileptic and died. The youngest

of her three first children has been married and had three children, one

of whom is afflicted with chorea Sancti Viti, and another is nearly an

ideot.

Of the causes termed moral, the greatest number may, perhaps, be traced to

the errors of education, which often plant in the youthful mind those

seeds of madness which the slightest circumstances readily awaken into

growth.

It should be as much the object of the teachers of youth, to subjugate the

passions, as to discipline the intellect. The tender mind should be

prepared to expect the natural and certain effects of causes: its

propensity to indulge an avaricious thirst for that which is unattainable,

should be quenched: nor should it be suffered to acquire a fixed and

invincible attachment to that which is fleeting and perishable.

Of the more immediate, or, as it is generally termed, the proximate cause

of this disease, I profess to know nothing. Whenever the functions of the

brain shall be fully understood, and the use of its different parts

ascertained, we may then be enabled to judge, how far disease, attacking

any of these parts, may increase, diminish, or otherwise alter its

functions. But this is a degree of knowledge, which we are not likely soon

to attain. It seems, however, not improbable, that the only source, from

whence the most copious and certain information can be drawn, is a strict

attention to the particular appearances which morbid states of this organ

may present.

From the preceding dissections of insane persons, it may be inferred, that

madness has always been connected with disease of the brain and of its

membranes. Having no particular theory to build up, they have been related

purely for the advancement of science and of truth.

It may be a matter, affording much diversity of opinion, whether these

morbid appearances of the brain be the cause or the effect of madness: it

may be observed that they have been found in all states of the disease.

When the brain has been injured from external violence, its functions have

been generally impaired, if inflammation of its substance, or more

delicate membranes has ensued. The same appearances have for the most part

been detected, when patients have died of phrenitis, or in the delirium of

fever: in these instances, the derangement of the intellectual functions

appears evidently to have been caused by the inflammation. If in mania the

same appearances be found, there will be no necessity of calling in the

aid of other causes, to account for the effect: indeed, it would be

difficult to discover them.

Those who entertain an opposite opinion are obliged to suppose, _a disease

of the mind_. Such a morbid affection, from the limited nature of my

powers, perhaps I have never been able to conceive. Possessing, however,

little knowledge of metaphysical controversy, I shall only offer a few

remarks upon this part of the subject, and beg pardon for having at all

touched it.

Perhaps it is not more difficult to suppose, that matter, peculiarly

arranged, may _think_,[17] than to conceive the union of an immaterial

being with a corporeal substance. It is questioning the infinite wisdom

and power of the Deity to say, that he does not, or cannot, arrange matter

so that it shall think. When we find insanity, as far as has been hitherto

observed, uniformly accompanied with disease of the brain, is it not more

just to conclude, that such organic affection has produced this incorrect

association of ideas, than that a being, which is immaterial,

incorruptible, and immortal, should be subject to the gross and

subordinate changes which matter necessarily undergoes?

But let us imagine _a disease of ideas_. In what manner are we to effect a

cure? To this subtle spirit the doctor can apply no medicines. Though so

refined as to elude the force of material remedies, some may however think

that it may be reasoned with. The good effects which have resulted from

exhibiting logic as a remedy for madness, must be sufficiently known to

every one who has conversed with insane persons, and must be considered as

time very judiciously employed: speaking more gravely, it will readily be

acknowledged, by persons acquainted with this disease, that, if insanity

be a disease of ideas, we can possess no corporeal remedies for it: and

that an endeavour to convince madmen of their errors, by reasoning, is

folly in those who attempt it, since there is always in madness the

firmest conviction of the truth of what is false, and which the clearest

and most circumstantial evidence cannot remove.

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