I seldom derived much advantage from the use of tonics and stimuli in

yellow fever; except when the powers of life seemed to fail, and

petechiae, vibices, haemorrhages, and other signs of malignancy had

occurred. In general, under such circumstances, the Peruvian bark,

either alone or combined with serpentaria, was administered in

preference to any other remedy of the same class. In cases, however,

unattended with reaction, tonics and diffusible stimuli internally, and

revulsives of all sorts externally, were had recourse to from the

commencement of the attack, and sometimes with the desired effect of

arousing the powers of the system. _Opium_ was never found beneficial,

on account of its tendency to aggravate or produce coma, as well as from

its effect in suppressing intestinal evacuations.

Whilst making use of the above remedies, the plentiful exhibition of

diluent drinks was not neglected,--care being taken, however, not to

load unduly the stomach, and to select such drinks as would suit the

taste of the patient. In almost every case, acids did not answer so well

as the bland mucilaginous infusions. The drinks were almost universally

allowed cold, except when there existed a tendency to perspiration;

under which circumstances they were administered slightly warm and a

little aromatic.

During the course of the yellow fever, some of the symptoms demanded

particular attention. Influenced by the idea of prostration and

dissolution, many practitioners, and myself for some time among the

rest, resorted to the bark and other tonics for the purpose of arresting

the black vomit, and of correcting that condition of the organs, which

gave rise to this effusion; but after many unsuccessful trials, I was

led to abandon this practice and to resort to other means. Of all the

remedies employed to attain this effect, calcined magnesia mixed in a

thick solution of gum arabic seemed to me to answer best; for whilst it

succeeded, in many cases, in arresting the vomiting, it tended to keep

the bowels open. Together with this, revulsive remedies were applied to

the skin, and sometimes succeeded very well,--a sufficient proof, I

think, that this haemorrhage is the effect of an increased action of the

mucous membrane of the digestive tube, and not of a passive condition of

the capillaries of the parts. For the purpose of controlling the great

irritability of the stomach, and arresting the vomiting occurring in the

early stage of the disease, besides the usual remedies used in such

cases, I found advantage in the use of small and frequently repeated

injections with a solution of salts, an infusion of senna, or the like

substances. Such a practice, however, did not seem to succeed so well in

the latter stage of the disease.

With the intention of promoting the secretion of urine, in cases in

which it was suppressed, all the diuretics, as well as every external

stimuli, were in vain employed;--this symptom, as I have already

mentioned, being, in all instances which fell under my immediate

observation, the forerunner of death.

ARTICLE V.--_Remarks on the Prophylactic Treatment of Cholera Infantum._

By JOSEPH PARRISH, M. D., one of the Surgeons to the Pennsylvania

Hospital.

The great mortality of cholera infantum renders it one of the most

interesting diseases, which come under the notice of the physician. Its

ravages among the infant population of our large cities, are too well

known, and too strongly felt, to require any comment. No disease

contributes so largely to swell our bills of mortality during its

prevalence; and were it not restricted to the summer season, it would

prove a greater scourge to the community than consumption itself.

This mortality is owing less to our ignorance of the nature of the

complaint, and the proper mode of treatment, than to the continued

operation of the causes by which it is produced. I have often compared

our endeavours to cure cholera infantum, while these causes remain, to

an attempt to relieve inflammation in a part, while a thorn is sticking

in the flesh. We may resort to bleeding and leeching; we may restrict

our patient to the lowest diet, and the most perfect rest; we may employ

all those remedies, which are ordinarily best calculated to reduce

inflammation: but so long as the thorn continues in the wound, our

efforts will be fruitless. Thus it is with cholera. We may obviate the

more violent symptoms; we may procure temporary relief; we may even

flatter ourselves that a cure has been effected: but the original causes

have not lost their power; an increased susceptibility to their

operation remains; relapse upon relapse is experienced; and at last the

little sufferer, worn out by the successive attacks, sinks beyond the

reach of medicine, and expires. Unhappily, the nature of the causes is

such, that, in very many instances, their removal is exceedingly

difficult, if not altogether impossible; and, under such circumstances,

the patient who has once been severely affected, seldom recovers in the

end. Hence it becomes of the greatest importance to prevent the

occurrence of the disease; and attention to the prophylactic treatment

is no less essential than the adoption of curative measures. It is with

the view of calling the attention of the profession to this subject,

that I have been induced to offer the following observations.

It is obvious, that, in the preventive treatment, two objects demand

attention; first, to remove, as far as possible, the causes of the

disease; and secondly, where their entire removal is not attainable, to

fortify the system against their influence. On each of these, I shall

offer a few observations.

I. Excessive and continued heat is, perhaps, the most fruitful source of

cholera. Thus we find, that the disease makes its first appearance in

the commencement of the hot weather, increases and becomes more fatal

with the rise of the thermometer, and declines with the return of cool

weather in autumn. During its continuance, it may be observed to vary

with every permanent change of temperature. A few very hot days in

succession, in the 6th month, are sufficient to call it into action; and

during the height of its prevalence, a spell of cold weather will

diminish, if not suppress it. In the summer of 1806, which was

remarkably cool and pleasant, there was very little of the disease; and

generally in moderate summers, it is much less prevalent than in those

of a contrary character.

I believe that it is by a direct operation on the system, and not by the

generation of miasmata, that heat proves so deleterious to the infant.

In the country, where miasmata are most abundant, there is comparatively

little cholera; for the heat of the sun is there moderated by the free

circulation of the air; and the debilitating operation of the high

temperature of the day is counteracted by the refreshing coolness of the

morning and evening. It is in the close air of cities, that the

complaint flourishes with greatest vigour; and the most confined

situations are the most favourable to its production. Let any one take

a walk, in a summer's morning, through the thickly built lanes and

alleys of Philadelphia. He will be struck with the appearance of the

children, reclining their heads, as if exhausted, upon the breast of

their mothers, with a pale and languid countenance, a cool and clammy

skin, a shrunk neck, and other signs of debility, arising from their

confinement, during the night, to close and hot apartments. It will

readily be believed, that such places are the very hot beds of cholera.

Heat, therefore, connected with confined air, being among the most

frequent causes of the complaint, it is necessary, as far as possible,

to counteract them. Should a strong predisposition to cholera be

suspected, the best plan will be to send the child into the country

during the summer. Both as a preventive and a remedy, country air is

decidedly the most effectual, to which we can resort. But in most

instances, it would be exceedingly inconvenient, sometimes impossible

for mothers to leave their homes and occupations in the city; and, under

such circumstances, it becomes necessary to substitute measures, which

may produce, as nearly as possible, the same effects. To keep the child

cool, and expose him to the fresh air, are the ends to be obtained. For

this purpose, he should be carried frequently into the open squares, or

beyond the suburbs of the city. I am in the habit of recommending to

parents, whose circumstances will not allow of a removal from the city

during the summer season, to make frequent excursions across the

Delaware, and into the neighbouring woods of New Jersey. The refreshing

effects of the air on the river are truly surprising. The brightened eye

and animated countenance of the infant, give speedy proof of their

favourable influence; and when labouring under the disease, even in its

lowest stage, the little patient will often exhibit immediate signs of

amendment.

In the prevention of cholera, much may also be expected from a proper

attention to the lodging of children. Many parents have a great dread of

the night air; and exclude it from their chambers, as sedulously as if

it were infected with poison. But, in guarding their children from

taking cold, they expose them to a much greater danger. Observe their

mode of treatment. The doors and windows are carefully closed; the child

is placed in a feather bed, with his parents on each side, and almost

smothered with the bed-clothes. Perhaps other children are lodged in the

same apartment; and thus the delicate system of the infant is exposed to

the debilitating influence of great heat and stagnant air, combined with

the effluvia, which, in such a situation, must be abundantly generated.

Simply to enter such a room in the morning, is almost sufficient to

sicken a healthy individual; how much more injurious must be its effects

upon the lodgers themselves. Examine in the morning a child, who has

passed the night thus confined. You will find him limber as a rag,

exhausted by perspiration, wholly destitute of animation, without

appetite, and on the very verge of cholera. I should recommend an

entirely different plan of management. Instead of a feather bed, the

child should be placed on a hard mattress, or on blankets folded and

laid upon the floor. The covering should be light, but comfortable. The

doors and windows should be open; so that fresh air, that _pabulum

vitae_, without which health cannot be sustained, may be freely admitted.

Thus treated, instead of the feeble and sickly appearance before

mentioned, he will present a lively countenance, with all that activity

of motion, and enjoyment of existence, which are natural to his age, and

afford the surest criterion of vigorous health. Experience has fully

convinced me of the great importance of attention to the lodging of

children, as a prophylactic measure; and this renders me desirous of

impressing upon the profession generally, the truth of my own

convictions on the subject.

With the same design of obviating the injurious effects of a high

temperature upon the infantile system, I advise frequent ablutions with

cool water, and its free employment as a beverage. Infants, unable to

make their wants known, often suffer exceedingly from the inability of

their attendants to understand them. During the heat of summer, the

increased evaporation from their surface is necessarily productive of

increased thirst, which, if unsatisfied, renders them uneasy and

restless. To quiet them, the breast or bottle is offered. Aliment is

thus given, where drink only was required; and the stomach, overloaded

and oppressed, is apt to become irritable, and is thus brought into a

condition most favourable to the occurrence of cholera. By attention to

the peculiar language of infants, expressed not by words, but by signs,

I have often been able to detect their wants; and, in many instances,

have afforded the most decided relief, by simply giving them a little

cool water for drink. From the dread which some individuals have for

cool air and cold water, it would seem that they were considered rather

as destructive poisons than as absolute necessaries. I have no fear of

either, when judiciously employed; and as prophylactics in cholera, I do

not think their place can be supplied.

But heat is not the only cause of this complaint. Dentition is well

known both to predispose the system to its attack, and, after it has

occurred, to increase its violence, and diminish the chances of

recovery. In the employment, therefore, of preventive measures, it is

highly necessary to attend to the state of the gums, and to remove or

counteract this source of irritation. If at all swelled or painful, they

should be lanced freely, and the operation should be repeated as often

as their inflammatory condition may demand. In severe cases, much good

may be expected from the application of blisters behind the ears. The

irritation thus receives an external direction, and the stomach and

bowels are in less danger of an attack. I was led to this practice, by

observing that the eruption, which, during dentition, is apt to make its

appearance behind the ears, often proves a most salutary effort of

nature; and that, while it continues, the infant generally enjoys an

exemption from those dangerous disorders, incident to this critical

period of life. To imitate nature as closely as possible, the discharge

from the blistered surface should be maintained for some time by

stimulating dressings. I have witnessed the most beneficial effects from

the practice, and can strongly recommend it to the attention of the

profession.

II. At the same time that we endeavour to remove or diminish the causes

of cholera, we should not neglect to put the system of the child in such

a condition, as may enable it most effectually to resist their

operation. As cholera is a disease of irritation, originating generally

in a debilitated state of the alimentary canal, I believe this end may

be most easily attained, by preserving the natural tone of the digestive

organs. For this purpose, all flatulent and indigestible food should be

carefully avoided. During the first year, the mother's milk is, in

general, the most appropriate nutriment. When the stomach of the infant

is very delicate, the diet of the mother should be strictly regulated;

and, in all cases, it would be adviseable for her to avoid articles of a

flatulent nature. While the child is still at the breast, if a

predisposition to cholera be suspected, I would recommend the occasional

use of nutritious animal juices. The sucking of small pieces of salt

meat, as ham or dried beef for example, will sometimes be found

productive of advantage. After weaning, animal food should always enter

into the diet of the child. Many parents, fearing to render their

children gross and unhealthy, restrict them altogether to vegetable

aliments; and thus, by weakening the powers of digestion, prepare the

way for that very result which they are most anxious to avoid.

With the same view of giving tone to the stomach, aromatics should be

used habitually during the summer, in those cases, in which there is

strong reason to apprehend the occurrence of cholera. While they produce

a cordial impression on the stomach, and invigorate generally the

digestive powers, they are liable to none of those objections which may

be urged against the employment of the narcotic stimulants. Indeed,

nature herself seems to have pointed them out as prophylactics against

the diseases of hot weather. Our most powerful and valuable spices are

the products of warm countries. Cinnamon, ginger, pepper, the clove, the

nutmeg, are to be found only in tropical climates. In this arrangement,

we see the hand of a beneficent Creator, who has provided, that, by the

same high temperature, which renders the equatorial regions so fruitful

of cholera, and other disorders of the bowels, the growth of those

plants should be promoted, which are best calculated to invigorate the

alimentary canal, and to fortify it against the inroads of disease.

Facts are not wanting to prove the efficacy of spices in preventing

intestinal complaints. We are informed by DEWAR, in his treatise on the

Diarrhoea and Dysentery, by which the British army in Egypt was

attacked, that among the Mamalukes of that country, it was a universal

practice, when they apprehended the approach of these disorders, to make

use of cinnamon or ginger, with the almost uniform effect of averting

them; and where the same practice was followed by the British soldiers,

equal advantages were experienced. In the French army, so highly was the

prophylactic power of the aromatics estimated, that every soldier was

provided with a box of spices, which he was directed to use freely with

his diet of fruit and melons.

When attending surgeon of the Alms-house hospital in this city, I had

occasion frequently to prescribe in a syphilitic ward, which being

situated directly under the roof, in a large garret, was liable, in the

summer season, to become very much heated. As the patients were

numerous, and the windows insufficient to admit of proper ventilation,

the air became much contaminated; and the consequence was, that bowel

complaints were very frequent and troublesome. I have often entered the

ward on a summer's morning, and found almost every patient affected more

or less with diarrhoea or cholera. It occurred to me, that the free

use of some of the aromatics might be found serviceable in preventing

the occurrence of these complaints. I accordingly directed, that every

individual in the ward should drink a portion of strong ginger tea

daily. I also ordered, that salt meat should be used twice in the week.

By the steady pursuit of this plan, a very considerable change for the

better was effected.

The employment of aromatics as prophylactics is not less beneficial in

children than in adults. I would not, however, advise, that they should

be given indiscriminately to all children, during the summer. It is only

to those cases, in which a predisposition to cholera infantum exists,

that I consider them peculiarly applicable; and here I believe they are

capable of producing much good.

Before dismissing the subject of the paper, I will simply remark, in

addition to what has been already said, that the occasional use of the

cold bath, by the vigour it imparts to the system generally, and through

it to the digestive organs, will often be found an excellent

preservative against the summer complaint of children.

In this short account of the preventive treatment of cholera infantum, I

have been less anxious to give a dissertation, embracing all that might

be said on the subject, than to communicate those particular measures,

which, according to my own experience, I have found most effectual. I

will conclude the paper by the relation of a case, in which a strong

predisposition to the disease was successfully counteracted. It will be

proper, however, to premise, that the treatment of this case is by no

means held out as an example to be generally followed with every

infant, which may possibly become the subject of cholera. It is

applicable in all its details only to those, in which, as in the present

instance, there is every reason to apprehend, that the only alternative

is between almost certain death, and the most careful prophylactic

treatment.

CASE.--A gentleman of this city, whose wife had arrived at a period of

life, when she could not expect to be the mother of many more children,

consulted me respecting an infant daughter, their only surviving child.

I was informed, that they had already lost eight children, all of whom,

with one exception, had died of cholera. It may readily be imagined,

that every feeling of parental anxiety was awakened for their babe; and

that no degree of attention on their part was considered too great,

which might contribute to its preservation. It was placed under my care,

not to be cured, but that I might, if possible, devise some plan of

management which would avert the disease they had so much reason to

apprehend. I felt the responsibility of the trust, and endeavoured to

find it to the best of my ability. Every opportunity which I could

desire was afforded me; for the infant, from its birth was submitted to

my direction; and both the disposition and ability existed, on the part

of the parents, to carry implicitly into effect every measure which I

might recommend.

As the mother was unable to furnish sufficient nourishment, the first

step was to provide a healthy wet-nurse, who might be willing to submit

to the necessary regulations in respect to diet.

I believed the children of these parents to possess a constitutional

weakness in the alimentary canal; and, on inquiry, I was told, that they

had been kept upon a vapid diet, under the impression that it would

contribute to their health. In the present case, therefore, the

principal object was to communicate strength to the stomach and bowels.

With this view, the child was accustomed, from an early period of

infancy, to a generous diet. When very young, portions of ginger tea

were given to it daily; and as soon as it was old enough to suck the

juice of meat, it was encouraged to do so. The nurse, during the warm

season, was kept upon a nutritious diet, consisting principally of

animal food, with the occasional use of ginger tea; and every

description of recent fruit and fresh vegetable food was forbidden.

Under this management, the first summer was passed without any symptom

of the disease; but I looked forward to the second with no little

anxiety, when the child would have to struggle with the irritation

arising from dentition.

The same plan was continued during the second summer, and still more

rigidly enforced. The child was now old enough to take animal food

freely in addition to the breast. It was allowed as much salt fish, ham,

beef-steak, essence of beef, &c. as it desired; ginger tea was given

daily; a little sound old port wine was occasionally directed; and both

the child and the nurse were restricted from every species of flatulent

and indigestible aliment. So anxious, indeed, were the parents, and so

careful to carry my directions into full effect, that they allowed no

forbidden article of food to enter the house, and denied themselves

their wonted comforts, lest possibly their child might be injured.

The gums were carefully attended to, and lanced whenever the operation

appeared to be requisite. All those measures, which I have before

mentioned as serviceable in obviating the effects of great heat, so far

as they were applicable to the case, were adopted. The second summer was

spent wholly in the country.

Very little medicine was required, and none was administered, except of

the mildest description. Frequently, when summoned to visit the babe, I

have found the mother trembling with fear, and anxious that something

might be done; and often, under such circumstances, have I begged it off

from a dose of physic, having determined to avoid a resort to every

thing of the kind, unless real necessity should demand it.

By a strict adherence to the plan above detailed, the period of

dentition was passed in safety; and it is with heartfelt pleasure I can

say, that no symptom of cholera afterwards made its appearance.

ARTICLE VI.--_Case of Neuralgia cured by Acupuncturation._ Communicated

by J. HUNTER EWING, M. D.

The attention of the medical public having been of late much excited on

the subject of acupuncturation, I am induced to communicate the

following case.

North American Medical and Surgical Journal, Vol. 2, No. 3, July, 1826 · 第 7 / 23 段